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Recent Start date Enrollment

HER2+ Metastatic Breast Cancer × Trastuzumab × Breast × Clear all

Phase

Status

Not yet recruiting 1

Sponsor Class

Study Type

Interventional 1

Sponsor

Cancer Type

Conditions

Breast Neoplasms 556 Neoplasm Metastasis 33 HER2-positive Breast Cancer 29 Breast Neoplasms, Male 27 Neoplasms 16 Brain Neoplasms 16 Inflammatory Breast Neoplasms 15 Stomach Neoplasms 13 Carcinoma, Non-Small-Cell Lung 12 Triple Negative Breast Neoplasms 11 Pancreatic Neoplasms 7 Ovarian Neoplasms 7 Endometrial Neoplasms 7 Colorectal Neoplasms 7 Esophageal Neoplasms 6 Cardiotoxicity 6 Pathologic Complete Response 5 Breast Diseases 5 Squamous Cell Carcinoma of Head and Neck 4 Sarcoma 4 Prostatic Neoplasms 4 Lung Neoplasms 4 HER2-positive Early Breast Cancer 4 Carcinoma, Ductal, Breast 4 Uterine Cervical Neoplasms 3 Urinary Bladder Neoplasms 3 HER2-positive Metastatic Breast Cancer 3 HER2 Positive Breast Cancer 3 Carcinoma, Ovarian Epithelial 3 Anatomic Stage I Breast Cancer AJCC v8 3

Interventions

asciminib 1 Trastuzumab 1

Date Range

30 days 90 days 1 year All

Options

Has results Has announcements

NCT07136428 2025-12-19

ASCENdANT

Duke University

Phase 1/2 Not yet recruiting

HER2+ Metastatic Breast Cancer

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