Combination of Letrozole, Everolimus and TRC105 in Postmenopausal Women With Hormone-Receptor Positive and Her2 Negative Breast Cancer
Phase 1/2 Completed
15 enrolled 18 charts
TACTIVE-E
Phase 1 Completed
32 enrolled
Comparison of Single-Agent Carboplatin vs the Combination of Carboplatin and Everolimus for the Treatment of Advanced Triple-Negative Breast Cancer
Phase 2 Completed
64 enrolled
MANTA
Phase 2 Completed
333 enrolled
Evaluation of the Safety and Tolerability of Niraparib With Everolimus in Advanced Gynecologic Malignancies and Breast
Phase 1 Completed
14 enrolled 12 charts
Liposomal Doxorubicin, Bevacizumab, and Everolimus in Patients With Locally Advanced TNBC With Tumors Predicted Insensitive to Standard Chemotherapy; A Moonshot Initiative
Phase 2 Completed
17 enrolled 8 charts
BOLERO-5
Phase 2 Completed
159 enrolled 25 charts
Study of Radium-223 Dichloride in Combination With Exemestane and Everolimus Versus Placebo in Combination With Exemestane and Everolimus in Subjects With Bone Predominant HER2 Negative Hormone Receptor Positive Metastatic Breast Cancer
Phase 2 Completed
283 enrolled 22 charts
Tamoxifen-RAD001 Versus Tamoxifen Alone in Patients With Anti-aromatase Resistant Breast Metastatic Cancer
Phase 2 Completed
111 enrolled
PEARL
Phase 2 Completed
55 enrolled
Everolimus in Treating Patients WIth Recurrent or Metastatic Breast Cancer
Phase 2 Completed
49 enrolled
BOLERO-4
Phase 2 Completed
202 enrolled 19 charts
A Study of PDR001 in Combination With LCL161, Everolimus or Panobinostat
Phase 1 Completed
298 enrolled
Palbociclib With Everolimus + Exemestane In BC
Phase 1/2 Completed
41 enrolled 12 charts
Study of the Glutaminase Inhibitor CB-839 in Solid Tumors
Phase 1 Completed
210 enrolled
Eribulin Mesylate and Everolimus in Treating Patients With Triple-Negative Metastatic Breast Cancer
Phase 1 Completed
27 enrolled 16 charts
A Trial of Neoadjuvant Everolimus Plus Letrozole Versus FEC in Women With ER-positive, HER2-negative Breast Cancer
Phase 2 Completed
40 enrolled
NECTAR
Phase 2 Completed
24 enrolled 7 charts
Phase Ib Trial of LEE011 With Everolimus (RAD001) and Exemestane in the Treatment of Hormone Receptor Positive HER2 Negative Advanced Breast Cancer
Phase 1 Completed
132 enrolled
Safety and Efficacy of RAD001 (Everolimus) in Combination With Letrozole in the Treatment of Postmenopausal Women With Locally Advanced or Metastatic Breast Cancer
Phase 2 Completed
72 enrolled 11 charts
BOLERO-6
Phase 2 Completed
309 enrolled 19 charts
Safety of Everolimus in Combination Therapy, in Patients With HER2-overexpressing Metastatic Breast Cancer
Phase 1 Completed
50 enrolled
Dose Finding Study of RAD001 (Everolimus, Afinitor®) in Combination With BEZ235 in Patients With Advanced Solid Tumors
Phase 1 Completed
46 enrolled
Everolimus, Letrozole and Trastuzumab in HR- and HER2/Neu-positive Patients
Phase 1 Completed
37 enrolled
Study of Safety and Efficacy of Alpelisib With Everolimus or Alpelisib With Everolimus and Exemestane in Advanced Breast Cancer Patients, Renal Cell Cancer and Pancreatic Tumors
Phase 1 Completed
79 enrolled
MAIN-A
Phase 3 Completed
110 enrolled
LEO
Phase 2 Completed
137 enrolled
EVEREXES
Phase 3 Completed
235 enrolled 11 charts
Everolimus Combined With Anti-estrogen Therapy in Hormone-Receptor-Positive HER-2 Negative Advanced Breast Cancer
Phase 2 Completed
48 enrolled 13 charts
Evaluation of Oral Care to Prevent Oral Mucositis in ER Positive MBC Patients Treated With Everolimus: Phase 3 RCT
Phase 3 Completed
174 enrolled
4EVERUK
Phase 4 Completed
52 enrolled 16 charts
BOLERO-1
Phase 3 Completed
719 enrolled 25 charts
Phase II Trial of EVEROLIMUS ± Trastuzumab in Hormone-Refractory Metastatic Breast Cancer
Phase 2 Completed
70 enrolled 12 charts
Cisplatin, Paclitaxel, and Everolimus in Treating Patients With Metastatic Breast Cancer
Phase 1/2 Completed
55 enrolled 12 charts
PrE0102
Phase 2 Completed
131 enrolled 12 charts
IMPROVE
Phase 4 Completed
85 enrolled
VicTORia
Phase 2 Completed
139 enrolled
BOLERO-2
Phase 3 Completed
724 enrolled 20 charts
BOLERO-3
Phase 3 Completed
569 enrolled 16 charts
BRE-43
Phase 2 Completed
33 enrolled 25 charts
MACS2096
Phase 3 Completed
301 enrolled
Open-label, Phase II Study of Stomatitis Prevention With a Steroid-based Mouthwash in Post-menopausal Women With Estrogen-receptor-positive (ER+), Human Epidermal Growth Factor Receptor 2 (HER2)- Metastatic or Locally Advanced Breast Cancer
Phase 2 Completed
92 enrolled 9 charts
Dose Escalation Followed by Study of RAD001 in Combination With Trastuzumab in HER2-Positive Metastatic Breast Cancer
Phase 1/2 Completed
11 enrolled 8 charts
Erlotinib and Everolimus in Treating Patients With Metastatic Breast Cancer
Phase 1 Completed
14 enrolled
GeparQuinto
Phase 3 Completed
2,600 enrolled
Danish Observational Study of Everolimus Plus Exemestane in Hormone Receptor (HR) Positive, Human Epidermal Growth Factor 2 (HER2) - Metastatic Breast Cancer
Completed
7 enrolled
Efficacy and Safety of Everolimus in Combination Therapy, in Patients With HER2-overexpressing Metastatic Breast Cancer
Phase 1 Completed
88 enrolled 10 charts
Cisplatin and Paclitaxel With or Without Everolimus in Treating Patients With Stage II or Stage III Breast Cancer
Phase 2 Completed
145 enrolled 10 charts
Trial of Paclitaxel/Bevacizumab +/- Everolimus for Patients With HER2-Negative Metastatic Breast Cancer
Phase 2 Completed
113 enrolled 9 charts
RAD001 Plus Carboplatin in Breast Cancer Patients
Phase 2 Completed
25 enrolled 9 charts