Clinical Trials Browser

OTHER × Metformin × Breast × Clear all

NCT06763328 2026-01-22

Metformin for the Treatment of Insulin Resistance in Women With Stage I-III Breast Cancer Completing Chemotherapy

Phase 3 Recruiting

Anatomic Stage I Breast Cancer AJCC v8

NCT05023967 2026-01-05

Metformin and Nightly Fasting in Women With Early Breast Cancer

Phase 2 Active not recruiting

Carcinoma, Intraductal, Noninfiltrating

NCT04300790 2025-07-29

METALLICA

Phase 2 Completed

BreastEndocrine

Breast Neoplasms, Hyperglycemia, Neoplasm Metastasis, Multiple Endocrine Neoplasia Type 1

NCT01905046 2025-04-13

Metformin Hydrochloride in Preventing Breast Cancer in Patients With Atypical Hyperplasia or In Situ Breast Cancer

Phase 3 Active not recruiting

86 enrolled 10 charts

Breast Carcinoma In Situ, Carcinoma, Intraductal, Noninfiltrating

NCT02488564 2025-02-03

met-HEReMYTA

Phase 2 Completed

HER-2 Positive Breast Cancer

NCT02431676 2024-08-28

SPIRIT

Phase 2 Completed

121 enrolled 12 charts

BreastDermatologicGastrointestinalGenitourinaryGynecologicThoracic

Breast Neoplasms, Colonic Neoplasms, Kidney Neoplasms, Liver Neoplasms, Lung Neoplasms, Melanoma, Pancreatic Neoplasms, Prostatic Neoplasms, Rectal Neoplasms, Endometrial Neoplasms

NCT00984490 2024-02-01

Metformin Hydrochloride in Treating Women With Stage I or Stage II Breast Cancer That Can Be Removed By Surgery

Phase NA Terminated

5 enrolled 4 charts

Breast Neoplasms

NCT01980823 2023-08-30

Pre-Surgical Trial of the Combination of Metformin and Atorvastatin in Newly Diagnosed Operable Breast Cancer

Phase EARLY_PHASE1 Completed

Breast Neoplasms

NCT04741204 2023-07-06

METBC

Phase 4 Withdrawn

Breast Neoplasms, Insulin Resistance, Racism

NCT02028221 2023-06-27

Phase II Study of Metformin for Reduction of Obesity-Associated Breast Cancer Risk

Phase 2 Completed

151 enrolled 15 charts

Breast Cancer Prevention

NCT05840068 2023-05-03

IGF Level in Breast Cancer Patients Treated With Metformin

Phase 4 Completed

Breast Neoplasms

NCT05351021 2023-03-09

Efficacy of Metformin as Preventive Treatment in Paclitaxel Induced Peripheral Neuropathy in Breast Cancer Patients

Phase 2 Completed

Breast Neoplasms, Peripheral Nervous System Diseases

NCT04248998 2023-01-18

BREAKFAST

Phase 2 Unknown

Triple Negative Breast Neoplasms

NCT02874430 2022-12-15

Metformin Hydrochloride and Doxycycline in Treating Patients With Localized Breast or Uterine Cancer

Phase 2 Unknown

Breast Neoplasms

NCT05507398 2022-10-31

The Anti-tumor Effect of Metformin And Atorvastatin in Breast Cancer

Phase 4 Unknown

Breast Cancer Female

NCT00930579 2022-10-20

Pre-Surgical Study: Effect of Metformin on Breast Cancer Proliferation

Phase 2 Completed

35 enrolled 5 charts

Breast Neoplasms

NCT04170465 2022-09-10

METNEO

Phase 2 Completed

Breast Cancer Female

NCT02278965 2022-08-17

Metformin and Omega-3 Fatty Acids in Woman With a History of Early Stage Breast Cancer

Phase 1 Completed

Breast Carcinoma In Situ, Breast Neoplasms

NCT03238495 2021-12-07

HERMET

Phase 2 Unknown

HER2-positive Breast Cancer

NCT04143282 2021-12-07

Evaluation of the Effect of Metformin on Metastatic Breast Cancer as Adjuvant Treatment

Phase 2 Completed

Breast Neoplasms

NCT05053841 2021-09-23

Implication of Metformin Plus Aromatase Inhibitor in Obese Postmenopausal Breast Cancer Women

Phase 2 Completed

Breast Neoplasms

NCT04559308 2020-09-22

The Effect of Metformin on Breast Cancer Patients

Phase 2 Unknown

Breast Neoplasms

NCT01627067 2020-06-19

Exemestane-RAD001-Metformin

Phase 2 Terminated

23 enrolled 7 charts

Breast Neoplasms

NCT04387630 2020-06-11

Neoadjuvant Chemotherapy With or Without Metformin in Early Breast Cancer.

Phase 2/3 Unknown

Breast Neoplasms

NCT01302379 2020-06-05

Reach for Health Study: Obesity-related Mechanisms and Mortality in Breast Cancer Survivors

Phase NA Completed

333 enrolled 17 charts

Breast Neoplasms, Obesity, Weight Loss

NCT04001725 2019-11-13

OPTIMAL

Phase 2 Unknown

BreastCNSDermatologicThoracic

Brain Neoplasms, Breast Neoplasms, Diabetes Mellitus, Lung Neoplasms, Melanoma, Neoplasms

NCT02506777 2019-09-04

MBC1

Phase 2 Unknown

Breast Neoplasms

NCT02506790 2019-09-04

Neoadjuvant Toremifene With Melatonin or Metformin in Locally Advanced Breast Cancer

Phase 2 Unknown

Breast Neoplasms

NCT01793948 2018-03-30

Metformin Hydrochloride vs. Placebo in Overweight or Obese Patients at Elevated Risk for Breast Cancer

Phase EARLY_PHASE1 Completed

Breast Neoplasms, Obesity

NCT01650506 2017-08-30

Study of Erlotinib and Metformin in Triple Negative Breast Cancer

Phase 1 Completed

Breast Neoplasms

NCT02360059 2017-08-17

Metformin for Reduction of Paclitaxel-Related Neuropathy in Patients With Breast Cancer

Phase 2 Terminated

1 enrolled 3 charts

Breast Neoplasms

NCT00933309 2016-02-19

The Impact of Obesity and Obesity Treatments on Breast Cancer

Phase 1 Completed

Breast Neoplasms, Obesity

NCT01885013 2016-01-01

MYME

Phase 2 Completed

Breast Neoplasms

NCT00909506 2015-07-29

Efficacy and Safety of Adjuvant Metformin for Operable Breast Cancer Patients

Phase 2 Completed

Breast Neoplasms

NCT01266486 2014-07-02

Effect of Metformin on Breast Cancer Metabolism

Phase 2 Completed

Breast Neoplasms

NCT01477060 2014-02-20

Modulation of Response to Hormonal Therapy With Lapatinib and/or Metformin in Patients With Metastatic Breast Cancer

Phase 2 Terminated

Breast Neoplasms

NCT00897884 2012-01-19

Clinical and Biologic Effects of Metformin in Early Stage Breast Cancer

Phase NA Completed

Breast Neoplasms