Clinical Trials

Breast Neoplasms, Neoplasm Metastasis, Recurrence

NCT00838929 2025-05-04

Study of the Combination of Vorinostat and Radiation Therapy for the Treatment of Patients With Brain Metastases

BreastClassical hematologyGastrointestinalGenitourinaryLymphoidMyeloidOther hematologic neoplasmPlasma cell

17 enrolled 8 charts

BreastCNSThoracic

Brain Neoplasms, Breast Neoplasms, Lung Neoplasms

NCT03878524 2024-03-04

Serial Measurements of Molecular and Architectural Responses to Therapy (SMMART) PRIME Trial

Phase 1 Terminated

2 enrolled

Anemia, Blast Crisis, Breast Neoplasms, Hodgkin Disease, Lymphoma, Non-Hodgkin, Multiple Myeloma, Myelodysplastic Syndromes, Myeloproliferative Disorders, Neoplasm Metastasis, Pancreatic Neoplasms, Prostatic Neoplasms, Thrombocytosis, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Accelerated Phase, Leukemia, Myeloid, Chronic-Phase, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Hematologic Neoplasms, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Myelodysplastic-Myeloproliferative Diseases, Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative, Primary Myelofibrosis

NCT04190056 2023-08-31

Pembrolizumab and Tamoxifen With or Without Vorinostat for the Treatment of Estrogen Receptor Positive Breast Cancer

1 enrolled 4 charts

Anatomic Stage IV Breast Cancer AJCC v8

NCT00574587 2020-10-14

Trial for Locally Advanced Breast Cancer Using Vorinostat Plus Chemotherapy

Phase 1/2 Completed

55 enrolled 10 charts

BreastGastrointestinalGynecologicHead & NeckThoracic

Breast Neoplasms

NCT01249443 2020-07-29

Paclitaxel and Carboplatin in Treating Patients With Metastatic or Recurrent Solid Tumors and HIV Infection

Phase 1 Terminated

17 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Ovarian Epithelial, Anus Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Esophageal Neoplasms, Salivary Gland Neoplasms, Stomach Neoplasms, HIV Infections

NCT02395627 2020-07-07

Reversing Therapy Resistance With Epigenetic-Immune Modification

38 enrolled 18 charts

Breast Neoplasms

NCT00262834 2020-02-19

Vorinostat in Treating Women Who Are Undergoing Surgery For Newly Diagnosed Stage I -III Breast Cancer

Phase 2 Completed

54 enrolled 7 charts

Breast Neoplasms

NCT01720602 2020-01-07

Vorinostat in Treating Patients With Stage IV Breast Cancer Receiving Hormone Therapy

Phase NA Completed

15 enrolled 10 charts

Breast Neoplasms, Breast Neoplasms, Male

NCT01118975 2019-11-13

GCC 0845:Vorinostat and Lapatinib in Advanced Solid Tumors and Advanced Breast Cancer to Evaluate Response and Biomarkers

Phase 1/2 Terminated

12 enrolled 6 charts

Breast Neoplasms, Neoplasm Metastasis

NCT01084057 2019-11-05

Ixabepilone and Vorinostat in Treating Patients With Metastatic Breast Cancer

56 enrolled

Breast Neoplasms, Breast Neoplasms, Male

NCT01153672 2019-09-06

Vorinostat in Treating Patients With Stage IV Breast Cancer Receiving Aromatase Inhibitor Therapy

Phase NA Completed

8 enrolled 10 charts

Breast Neoplasms, Breast Neoplasms, Male

NCT00788112 2017-08-07

Vorinostat in Treating Women With Ductal Carcinoma in Situ of the Breast

17 enrolled

Breast Neoplasms, Carcinoma, Intraductal, Noninfiltrating

NCT00126451 2017-04-10

A Clinical Trial of Oral Suberoylanilide Hydroxamic Acid (SAHA) in Patients With Relapsed or Refractory Breast, Colorectal and Non-Small Cell Lung Cancer (0683-011)(TERMINATED)

BreastGastrointestinalThoracic

16 enrolled

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Colorectal Neoplasms

NCT00719875 2017-03-03

HDAC Inhibitor Vorinostat (SAHA) With Capecitabine (Xeloda) Using a New Weekly Dose Regimen for Advanced Breast Cancer

24 enrolled

Advanced Breast Cancer

NCT00368875 2015-11-05

Phase I-II Study of Vorinostat, Paclitaxel, and Bevacizumab in Metastatic Breast Cancer

Phase 1/2 Completed

54 enrolled 9 charts

Breast Neoplasms, Breast Neoplasms, Male

NCT00132002 2015-03-19

Suberoylanilide Hydroxamic Acid in Treating Patients With Progressive Stage IV Breast Cancer

14 enrolled 6 charts

Breast Neoplasms, Breast Neoplasms, Male

NCT00365599 2014-11-21

Phase II Trial of SAHA & Tamoxifen for Patients With Breast Cancer

Phase 2 Completed

43 enrolled 8 charts

Breast Neoplasms, Neoplasm Metastasis, Bulbo-Spinal Atrophy, X-Linked

NCT01695057 2014-01-28

Vorinostat Before Surgery in Treating Patients With Triple-Negative Breast Cancer

Phase NA Withdrawn

Breast Neoplasms, Triple Negative Breast Neoplasms

NCT00416130 2013-12-10

Clinical Trial of SAHA in Patients With Breast Cancer

Phase 1/2 Unknown

49 enrolled

Breast Neoplasms

NCT00045006 2013-05-30

Suberoylanilide Hydroxamic Acid in Treating Patients With Advanced Cancer

BreastCNSDermatologicGenitourinaryGynecologicHead & NeckLymphoidMyeloidOther hematologic neoplasmPlasma cellThoracic

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Ovarian Epithelial, Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Hodgkin Disease, Leukemia, Hairy Cell, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Multiple Myeloma, Mycosis Fungoides, Myeloproliferative Disorders, Neoplasms, Oropharyngeal Neoplasms, Prostatic Neoplasms, Salivary Gland Neoplasms, Sezary Syndrome, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Biphenotypic, Acute, Leukemia, Prolymphocytic, Leukemia, Myeloid, Acute, Lymphoma, Large B-Cell, Diffuse, Lymphoma, T-Cell, Cutaneous, Esthesioneuroblastoma, Olfactory, Breast Neoplasms, Male, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative

NCT01194427 2013-05-17

A Study of Vorinostat and Tamoxifen in Newly Diagnosed Breast Cancer

2 enrolled 3 charts