Clinical Trials

Phase NA Active not recruiting

Breast Neoplasms

NCT06876636 2025-07-29

Zoledronic Acid Combined With EC-T for Triple-Negative Breast Cancer

99 enrolled

Breast Cancer Metastatic

NCT00295646 2024-03-15

Tamoxifen Versus Anastrozole, Alone or in Combination With Zoledronic Acid

1,803 enrolled 20 charts

Breast Neoplasms

NCT00556374 2023-07-27

Study to Determine Treatment Effects of Denosumab in Patients With Breast Cancer Receiving Aromatase Inhibitor Therapy

3,420 enrolled 19 charts

Breast Neoplasms

NCT00412022 2023-03-24

HOBOE

1,294 enrolled

Breast Neoplasms

NCT00321464 2022-11-08

A Study Comparing Denosumab vs. Zoledronic Acid for the Treatment of Bone Metastases in Breast Cancer Subjects.

2,049 enrolled 16 charts

Breast Neoplasms, Fractures, Bone

NCT00458796 2022-05-27

Comparison of Two Schedules of Zoledronic Acid in Treating Patients With Breast Cancer That Has Spread to the Bone

Phase NA Terminated

1,500 enrolled

Humoral Hypercalcemia Of Malignancy, Breast Neoplasms, Neoplasm Metastasis, Pain, Breast Neoplasms, Male

NCT00566618 2022-02-25

Dasatinib in Combination With Zoledronic Acid for the Treatment of Breast Cancer With Bone Metastasis

Phase 1/2 Completed

31 enrolled 8 charts

Breast Neoplasms

NCT05164952 2021-12-21

Delayed Versus Immediate Use Of Zoledronic Acid For Postmenopausal Patients With Early Breast Cancer Who Are Using Adjuvant Letrozole

50 enrolled

Breast Neoplasms

NCT00127205 2021-07-02

S0307 Phase III Trial of Bisphosphonates as Adjuvant Therapy for Primary Breast Cancer.

6,097 enrolled 20 charts

Breast Neoplasms

NCT01623908 2021-06-22

BLAZE

Phase NA Terminated

200 enrolled

Bone Diseases, Metabolic, Breast Neoplasms

NCT00424983 2020-12-21

Study of Zoledronic Acid Administered Monthly Versus Every 3 Months in Multiple Myeloma and Breast Cancer Patients Who Were Treated With Zoledronic Acid the Prior Year

Phase 1 Completed

18 enrolled

BreastPlasma cell

Breast Neoplasms, Multiple Myeloma

NCT00295867 2020-05-12

Zoledronate in Treating Bone Marrow Micrometastases in Women With Stage I, Stage II, or Stage III Breast Cancer

45 enrolled 9 charts

Breast Neoplasms

NCT01409811 2020-05-08

Biomarkers in Tissue Samples From Patients With Newly Diagnosed Breast Cancer Treated With Zoledronic Acid

Phase NA Terminated

9 enrolled 3 charts

Breast Neoplasms, Carcinoma, Ductal, Breast

NCT00305695 2020-03-24

Zoledronate or Observation in Maintaining Bone Mineral Density in Patients Who Are Undergoing Surgery to Remove Both Ovaries

160 enrolled 10 charts

BreastGynecologic

Osteoporosis, Ovarian Neoplasms, Hereditary Breast and Ovarian Cancer Syndrome

NCT01099436 2020-01-21

NEO-ZOTAC

250 enrolled

Breast Neoplasms

NCT00213980 2019-11-27

Bone Mineral Density Effects of Zoledronate in Postmenopausal Women With Breast Cancer

68 enrolled 11 charts

Breast Neoplasms

NCT01367288 2019-05-28

NEOZOL

53 enrolled

Breast Neoplasms, Neovascularization, Pathologic

NCT00130494 2019-04-16

Zoledronic Acid Administration to Metastatic Breast Cancer Patients With Non-symptomatic Bone Lesions

Phase 3 Terminated

97 enrolled

Breast Neoplasms, Neoplasm Metastasis

NCT00869206 2018-11-07

Zoledronic Acid in Treating Patients With Metastatic Breast Cancer, Metastatic Prostate Cancer, or Multiple Myeloma With Bone Involvement

BreastGenitourinaryPlasma cell

1,822 enrolled 19 charts

Breast Neoplasms, Multiple Myeloma, Pain, Prostatic Neoplasms

NCT01194440 2018-09-12

Zoledronic Acid in Aromatase Inhibitor Induced Musculoskeletal Symptoms

63 enrolled 7 charts

Breast Neoplasms, Carcinoma, Intraductal, Noninfiltrating

NCT00399802 2018-08-16

A Study to Examine the Effects of an Experimental Drug on Women With Breast Cancer and Metastatic Bone Disease (MBD)(0822-016)(COMPLETED)

43 enrolled 10 charts

Bone Diseases, Breast Neoplasms

NCT01907880 2017-07-07

ER11-03

74 enrolled

Breast Neoplasms, Pain

NCT01472146 2017-05-09

ZoNantax - Zolendronic Acid as Neoadjuvant Therapy Plus Anthracycline and Taxane in Locally Advanced Breast Cancer

58 enrolled

Breast Diseases, Breast Neoplasms, Neoplasms, Neoplasms by Site

NCT00434317 2017-02-23

Assessment of Pain and Quality of Life in Breast and Prostate Cancer Patients With Bone Metastases

80 enrolled

BreastGenitourinary

Breast Neoplasms, Neoplasm Metastasis, Neoplasms, Pain, Prostatic Neoplasms

NCT00334139 2017-02-07

Effect of Zoledronic Acid on Bone Metabolism in Patients With Bone Metastasis and Prostate or Breast Cancer

411 enrolled

BreastGenitourinary

Breast Neoplasms, Prostatic Neoplasms

NCT00107263 2016-12-06

Zoledronate in Preventing Bone Loss in Postmenopausal Women Who Are Receiving Letrozole for Stage I, Stage II, or Stage IIIA Breast Cancer

558 enrolled

Breast Neoplasms, Osteoporosis

NCT00022087 2016-07-19

Zoledronate, Calcium, and Vitamin D in Preventing Bone Loss in Women Receiving Adjuvant Chemotherapy for Breast Cancer

439 enrolled

Breast Neoplasms, Osteoporosis

NCT00903162 2016-04-18

Extended Endocrine Therapy for Premenopausal Women With Breast Cancer

17 enrolled 5 charts

Breast Neoplasms

NCT00582920 2015-12-24

Investigation of Changes in Bone Scan Imaging Before and After Intravenous Bisphosphonate Therapy for Osseous Metastases From Breast Cancer

Phase 1 Completed

10 enrolled

Breast Neoplasms

NCT02595138 2015-11-03

Zoledronic Acid as Adjuvant Treatment of Triple-negative Breast Cancer

430 enrolled

Triple Negative Breast Neoplasms

NCT01067989 2015-07-08

Low-Dose/Metronomic(LDM)Chemotherapy for Metastatic Breast Cancer

Phase 2 Terminated

22 enrolled

Breast Neoplasms, Neoplasm Metastasis

NCT01344967 2015-06-23

SuBDuE

Phase 2/3 Completed

21 enrolled

Metastatic Breast Cancer With Bone Involvement

NCT00512993 2015-03-05

NATAN

654 enrolled

Breast Neoplasms

NCT00333229 2014-11-25

A Study of Zoledronic Acid in the Prevention of Cancer Therapy-induced Bone Loss

Phase 4 Terminated

11 enrolled 6 charts

Breast Neoplasms

NCT00320710 2014-08-22

Continued Efficacy and Safety of Zoledronic Acid (q 4 Wks vs. q 12 Wks) in the 2nd Year of Treatment in Patients With Bone Metastases From Breast Cancer

416 enrolled 10 charts

Breast Neoplasms

NCT00712985 2014-04-24

CTIBL

18 enrolled 5 charts

Breast Neoplasms

NCT00049452 2014-01-06

Zoledronate in Preventing Bone Loss in Premenopausal Women Receiving Chemotherapy After Surgery For Early Stage Breast Cancer

120 enrolled

Breast Neoplasms, Osteoporosis

NCT00301886 2013-11-13

S0308 Zoledronate or Ibandronate in Preventing Bone Problems in Women With Stage IV Breast Cancer That Has Spread to the Bone

Phase 3 Withdrawn

Humoral Hypercalcemia Of Malignancy, Breast Neoplasms, Neoplasm Metastasis, Pain

NCT00242203 2013-08-13

Evaluation of Chemotherapy Prior to Surgery With or Without Zometa for Women With Locally Advanced Breast Cancer

120 enrolled

Breast Neoplasms, Neoplasm Micrometastasis

NCT00072020 2013-08-02

Chemotherapy and/or Hormone Therapy With or Without Zoledronate in Treating Women With Stage II or Stage III Breast Cancer

Breast Neoplasms, Neoplasm Metastasis

NCT00060138 2013-05-15

Monoclonal Antibody Compared With Zoledronate in Treating Women With Breast Cancer and Bone Metastases

Phase 1/2 Completed

Humoral Hypercalcemia Of Malignancy, Breast Neoplasms, Neoplasm Metastasis, Pain

NCT00114270 2013-03-26

Letrozole With or Without Zoledronate in Treating Healthy Postmenopausal Women With High Breast Density

Phase NA Completed

Breast Neoplasms, Osteoporosis

NCT00326820 2013-03-13

Ibandronate or Zoledronate in Treating Patients With Newly Diagnosed Bone Metastases From Breast Cancer

1,404 enrolled

Humoral Hypercalcemia Of Malignancy, Breast Neoplasms, Neoplasm Metastasis, Breast Neoplasms, Male

NCT00171340 2012-04-16

Zoledronic Acid in the Prevention of Cancer Treatment Related Bone Loss in Postmenopausal Women Receiving Letrozole for Breast Cancer.

1,065 enrolled 10 charts

Bone Diseases, Metabolic, Breast Neoplasms

NCT00171314 2012-04-11

The Use of Zoledronic Acid to Prevent Cancer-treatment Bone Loss in Post-menopausal Women Receiving Adjuvant Letrozole for Breast Cancer

527 enrolled 11 charts

Breast Neoplasms

NCT00375427 2012-04-11

Safety and Efficacy of Zoledronic Acid in Patients With Breast Cancer With Metastatic Bone Lesions

430 enrolled 12 charts

Breast Neoplasms

NCT00029224 2012-02-01

Treatment With Zoledronic Acid in Patients With Breast Cancer, Multiple Myeloma, and Prostate Cancer With Cancer Related Bone Lesions

BreastGenitourinaryPlasma cell

500 enrolled

Breast Neoplasms, Multiple Myeloma, Pain, Prostatic Neoplasms

NCT00332709 2011-11-16

Safety/Efficacy of Letrozole Monotherapy or in Combination With Zoledronic Acid as Extended Adjuvant Treatment of Postmenopausal Patients With Primary Breast Cancer

83 enrolled 14 charts