NCT01482156 2020-12-21Dose Finding Study of RAD001 (Everolimus, Afinitor®) in Combination With BEZ235 in Patients With Advanced Solid TumorsNovartisPhase 1 Completed46 enrolled
NCT00620594 2020-12-09A Phase I/II Study of BEZ235 in Patients With Advanced Solid Malignancies Enriched by Patients With Advanced Breast CancerNovartisPhase 1 Completed183 enrolled
NCT01495247 2020-12-08Phase Ib/II Trial of BEZ235 With Paclitaxel in Patients With HER2 Negative, Locally Advanced or Metastatic Breast CancerNovartisPhase 1/2 Terminated18 enrolled
NCT01337765 2020-10-09Safety, Pharmacokinetics and Pharmacodynamics of BEZ235 Plus MEK162 in Selected Advanced Solid Tumor PatientsPfizerPhase 1 Completed29 enrolled
NCT01248494 2016-07-25PhIb BKM120 or BEZ235+Endocrine Treatment in Post-Menopausal Patients With Hormone Receptor + Metastatic Breast CancerVanderbilt-Ingram Cancer CenterPhase 1 Completed72 enrolled
NCT01288092 2012-06-07BEZ235 Trial in Patients With HER2-(Human Epidermal Growth Factor Receptor 2 Negative) /HR+ (Hormonal Receptor Positive) Metastatic Breast CancerNovartisPhase 2 Withdrawn