NCT07405801 2026-03-09A Phase II Study Evaluating the Efficacy and Safety of Inavolisib Plus Ribociclib Plus Fulvestrant Versus Placebo Plus Ribociclib Plus Fulvestrant in Participants With Advanced Breast CancerHoffmann-La RochePhase 2 Recruiting80 enrolled
NCT07441512 2026-03-02A Phase II, Single-arm Study to Evaluate the Efficacy and Safety of Inavolisib in Combination With Eribulin in Pretreated Advanced Triple-negative Breast Cancer Harboring a PIK3CA MutationZhejiang Cancer HospitalPhase 2 Not yet recruiting26 enrolled
NCT07245797 2025-11-24A Phase II, Multicenter, Open-label Study to Evaluate the Efficacy and Safety of Neoadjuvant Therapy With Inavolisib Plus Pertuzumab and Trastuzumab as Subcutaneous (PH-FDC SC) and 3-week Cycle Nab-paclitaxel for PIK3CA-mutated, HER2+, eBCFudan UniversityPhase 2 Not yet recruiting164 enrolled
NCT04849364 2025-05-31PERSEVEREHoosier Cancer Research NetworkPhase 2 Terminated52 enrolled 16 charts
NCT05332561 2025-03-20Genomics Guided Targeted Post-neoadjuvant Therapy in Patients With Early Breast Cancer (COGNITION-GUIDE)German Cancer Research CenterPhase 2 Recruiting240 enrolled