Clinical Trials

99 enrolled

HER2/Neu Negative

NCT05941520 2026-03-18

Acolbifene Versus Low Dose Tamoxifen for the Prevention of Breast Cancer in Premenopausal Women at High Risk for Development of Breast Cancer

80 enrolled

Breast Carcinoma In Situ, Breast Neoplasms, Carcinoma, Intraductal, Noninfiltrating

NCT06184750 2026-03-18

Finding the Best Tamoxifen Dose for Breast Cancer Risk Reduction in Premenopausal Women, RENAISSANCE Trial

200 enrolled

Breast Carcinoma In Situ, Breast Neoplasms, Carcinoma, Intraductal, Noninfiltrating

NCT03412877 2026-03-17

Administration of Autologous T-Cells Genetically Engineered to Express T-Cell Receptors Reactive Against Neoantigens in People With Metastatic Cancer

BreastEndocrineGynecologicNETPlasma cellThoracic

285 enrolled

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Multiple Myeloma, Ovarian Neoplasms, Urogenital Neoplasms, Neuroendocrine Tumors

NCT03598257 2026-03-17

Radiation Therapy With or Without Olaparib in Treating Patients With Inflammatory Breast Cancer

300 enrolled

Inflammatory Breast Neoplasms

NCT01174121 2026-03-04

Immunotherapy Using Tumor Infiltrating Lymphocytes for Patients With Metastatic Cancer

BreastGastrointestinalGynecologic

332 enrolled

Breast Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Urogenital Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms

NCT05554354 2026-03-03

Testing the Use of Fulvestrant and Binimetinib Targeted Treatment for NF1 Mutation in Hormone Receptor-Positive Metastatic Breast Cancer (A ComboMATCH Treatment Trial)

1 enrolled

Anatomic Stage IV Breast Cancer AJCC v8

NCT02849496 2025-11-24

Testing Olaparib Either Alone or in Combination With Atezolizumab in BRCA Mutant Non-HER2-positive Breast Cancer

81 enrolled

Breast Neoplasms

NCT02883062 2025-10-16

Carboplatin and Paclitaxel With or Without Atezolizumab Before Surgery in Treating Patients With Newly Diagnosed, Stage II-III Triple-Negative Breast Cancer

67 enrolled 16 charts

Breast Neoplasms, Triple Negative Breast Neoplasms

NCT00861705 2025-09-30

Paclitaxel With or Without Carboplatin and/or Bevacizumab Followed by Doxorubicin and Cyclophosphamide in Treating Patients With Breast Cancer That Can Be Removed by Surgery

454 enrolled 23 charts

Breast Neoplasms, Breast Neoplasms, Male, Triple Negative Breast Neoplasms

NCT02498613 2025-09-25

A Phase 2 Study of Cediranib in Combination With Olaparib in Advanced Solid Tumors

122 enrolled 16 charts

BreastThoracic

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Small Cell Lung Carcinoma, Triple Negative Breast Neoplasms

NCT01149083 2025-08-15

Veliparib With or Without Carboplatin in Treating Patients With Stage III or IV Breast Cancer

77 enrolled 17 charts

Breast Neoplasms

NCT02595905 2025-05-16

Cisplatin With or Without Veliparib in Treating Patients With Recurrent or Metastatic Triple-Negative and/or BRCA Mutation-Associated Breast Cancer With or Without Brain Metastases

344 enrolled

BreastCNS

Brain Neoplasms, Breast Neoplasms, Triple Negative Breast Neoplasms

NCT01349959 2025-04-27

Azacitidine and Entinostat in Treating Patients With Advanced Breast Cancer

58 enrolled 16 charts

Breast Neoplasms, Breast Neoplasms, Male, Triple Negative Breast Neoplasms

NCT05967286 2024-03-20

Olaparib and Alpelisib for Treatment of Metastatic Breast Cancer, A ComboMATCH Treatment Trial

Phase 2 Withdrawn

BreastGynecologicThoracic

Anatomic Stage III Breast Cancer AJCC v8

NCT04102436 2024-03-12

Non-Viral TCR Gene Therapy

Phase 2 Withdrawn

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Ovarian Neoplasms, Urogenital Neoplasms

NCT00096434 2024-03-07

Sorafenib in Treating Patients With Metastatic Breast Cancer

23 enrolled

Breast Neoplasms, Breast Neoplasms, Male

NCT02636582 2023-12-05

Nelipepimut-S Plus GM-CSF Vaccine Therapy in Treating Patients With Breast Cancer

43 enrolled 10 charts

Carcinoma, Intraductal, Noninfiltrating

NCT01142401 2023-11-27

Fulvestrant With or Without Bortezomib in Patients With Inoperable Locally Advanced or Metastatic Estrogen Receptor Positive Breast Cancer

118 enrolled 11 charts

Breast Neoplasms

NCT01622868 2023-10-17

Whole-Brain Radiation Therapy or Stereotactic Radiosurgery With or Without Lapatinib Ditosylate in Treating Patients With Brain Metastasis From HER2-Positive Breast Cancer

143 enrolled 24 charts

BreastCNS

Brain Neoplasms, Breast Neoplasms

NCT02598557 2023-08-22

Alternative Dosing of Exemestane Before Surgery in Treating Postmenopausal Patients With Stage 0-II Estrogen Positive Breast Cancer

180 enrolled 46 charts

Breast Carcinoma In Situ, Breast Neoplasms

NCT02203513 2022-09-10

A Phase II Single Arm Pilot Study of the Chk1/2 Inhibitor (LY2606368) in BRCA1/2 Mutation Associated Breast or Ovarian Cancer, Triple Negative Breast Cancer, High Grade Serous Ovarian Cancer, and Metastatic Castrate-Resistant Prostate Cancer

BreastGenitourinaryGynecologic

111 enrolled 15 charts

Breast Neoplasms, Ovarian Neoplasms, Prostatic Neoplasms, Hereditary Breast and Ovarian Cancer Syndrome

NCT03394027 2022-08-23

ONC201 in Recurrent/Refractory Metastatic Breast Cancer and Advanced Endometrial Carcinoma

30 enrolled 15 charts

BreastGynecologic

Neoplasm Metastasis, Endometrial Neoplasms, Breast Neoplasms, Male, Triple Negative Breast Neoplasms

NCT01849250 2021-12-28

Study of Docosahexaenoic Acid (DHA) in Triple Negative Breast Cancer Survivors

65 enrolled 11 charts

Breast Carcinoma In Situ, Breast Neoplasms, Carcinoma, Intraductal, Noninfiltrating, Paget's Disease, Mammary

NCT01967823 2021-03-24

T Cell Receptor Immunotherapy Targeting NY-ESO-1 for Patients With NY-ESO-1 Expressing Cancer

BreastCNSDermatologicGastrointestinalThoracic

11 enrolled 12 charts

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Liver Neoplasms, Melanoma, Meningioma, Neoplasm Metastasis

NCT00684983 2020-03-24

Capecitabine and Lapatinib Ditosylate With or Without Cixutumumab in Treating Patients With Previously Treated HER2-Positive Stage IIIB-IV Breast Cancer

64 enrolled 13 charts

Insulin-Like Growth Factor I, Resistance To, Breast Neoplasms

NCT00602043 2020-02-19

F-18 16 Alpha-Fluoroestradiol-Labeled Positron Emission Tomography in Predicting Response to First-Line Hormone Therapy in Patients With Stage IV Breast Cancer

20 enrolled 6 charts

Breast Neoplasms

NCT01624090 2019-12-30

Mithramycin for Lung, Esophagus, and Other Chest Cancers

BreastGastrointestinalOther solid neoplasmThoracic

16 enrolled 13 charts

Breast Neoplasms, Esophageal Neoplasms, Gastrointestinal Neoplasms, Lung Neoplasms, Mesothelioma

NCT03300843 2019-12-13

Ability of a Dendritic Cell Vaccine to Immunize Melanoma or Epithelial Cancer Patients Against Defined Mutated Neoantigens Expressed by the Autologous Cancer

BreastDermatologicGastrointestinalGynecologic

1 enrolled 7 charts

Breast Neoplasms, Gastrointestinal Neoplasms, Melanoma, Ovarian Neoplasms, Pancreatic Neoplasms

NCT01964924 2019-09-20

Trametinib and Akt Inhibitor GSK2141795 in Treating Patients With Metastatic Triple-Negative Breast Cancer

37 enrolled 17 charts

Breast Neoplasms, Triple Negative Breast Neoplasms

NCT01277757 2018-12-19

Akt Inhibitor MK2206 in Treating Patients With Advanced Breast Cancer

30 enrolled 7 charts

Breast Neoplasms

NCT00082810 2018-11-01

Tipifarnib and Fulvestrant in Hormone Receptor-Positive Metastatic Breast Cancer

33 enrolled 10 charts

Breast Neoplasms

NCT03377101 2018-08-14

Fulvestrant and Palbociclib With or Without Copanlisib in Treating Patients With Hormone Receptor Positive, HER2 Negative, Stage IV Breast Cancer

Phase 2 Withdrawn

Estrogen Receptor Positive

NCT00509587 2018-08-08

Pazopanib in Treating Patients With Recurrent or Metastatic Breast Cancer

21 enrolled 10 charts

Breast Neoplasms

NCT01776008 2018-05-08

Akt Inhibitor MK-2206 and Anastrozole With or Without Goserelin Acetate in Treating Patients With Stage II-III Breast Cancer

16 enrolled 5 charts

Breast Neoplasms

NCT00118157 2017-12-04

Lapatinib and Tamoxifen in Treating Patients With Locally Advanced or Metastatic Breast Cancer That Did Not Respond to Previous Tamoxifen

19 enrolled 6 charts

Breast Neoplasms, Breast Neoplasms, Male

NCT01688609 2017-09-11

Lapatinib Ditosylate, Trastuzumab, Paclitaxel, and Surgery in Treating Patients With Breast Cancer

18 enrolled 7 charts

Breast Neoplasms

NCT01319539 2017-08-30

MK2206 in Treating Patients With Stage I, Stage II, or Stage III Breast Cancer

12 enrolled 9 charts

Breast Neoplasms, Triple Negative Breast Neoplasms

NCT00054132 2017-07-24

Erlotinib Hydrochloride and Bevacizumab in Treating Patients With Stage IV Breast Cancer

38 enrolled 10 charts

Breast Neoplasms

NCT00016549 2017-07-02

Bevacizumab to Treat Inflammatory Breast Cancer or Locally Advanced Breast Cancer

21 enrolled

Breast Neoplasms, Inflammatory Breast Neoplasms

NCT00092950 2017-07-02

Exercise in Women at Risk for Breast Cancer

88 enrolled

Breast Neoplasms, Motor Activity, Patient Compliance

NCT01151449 2017-04-11

Gamma-secretase/Notch Signalling Pathway Inhibitor RO4929097 in Treating Patients With Advanced, Metastatic, or Recurrent Triple Negative Invasive Breast Cancer

6 enrolled 8 charts

Breast Neoplasms, Breast Neoplasms, Male, Triple Negative Breast Neoplasms

NCT00290758 2017-02-08

Genistein in Preventing Breast Cancer in Women at High Risk for Breast Cancer

126 enrolled 16 charts

Breast Neoplasms

NCT00096109 2017-01-16

Tanespimycin in Treating Women With Refractory Locally Advanced or Metastatic Breast Cancer

11 enrolled 6 charts

Breast Neoplasms

NCT00572728 2016-12-30

Phase II Study of Fluorine-18 3'-Deoxy-3'-Fluorothymidine (F-18-FLT) in Invasive Breast Cancer

90 enrolled 17 charts

Breast Neoplasms

NCT01339000 2016-06-22

Improving the Immune System With Human IL-7 Vaccine in Older Subjects Who Have Had Chemotherapy

BreastGastrointestinalGenitourinary

1 enrolled 5 charts

Urinary Bladder Neoplasms, Breast Neoplasms, Colonic Neoplasms, Colorectal Neoplasms

NCT01575522 2016-03-21

Tivantinib in Treating Patients With Recurrent or Metastatic Breast Cancer

22 enrolled 10 charts

Breast Neoplasms, Triple Negative Breast Neoplasms

NCT00244881 2015-12-07

A Phase II Study of AZD2171 in Breast Cancer Stage IV (10006202)

26 enrolled 9 charts

Breast Neoplasms, Breast Neoplasms, Male

NCT00132002 2015-03-19

Suberoylanilide Hydroxamic Acid in Treating Patients With Progressive Stage IV Breast Cancer

14 enrolled 6 charts

Breast Neoplasms, Breast Neoplasms, Male

NCT00068588 2014-10-31

GTI-2040 and Capecitabine in Treating Patients With Metastatic Breast Cancer

24 enrolled 4 charts