Adding an Immunotherapy Drug, MEDI4736 (Durvalumab), to the Usual Chemotherapy Treatment (Paclitaxel, Cyclophosphamide, and Doxorubicin) for Stage II-III Breast Cancer
Phase 3 Recruiting
3,680 enrolled
The CDK4/6 Inhibitor Dosing Knowledge (CDK) Study
Phase 3 Recruiting
500 enrolled
TB06
Phase 3 Recruiting
100 enrolled
AK112 or Placebo Plus Nab-Paclitaxel as First-line Treatment in Inoperable Locally Advanced/ Metastatic Triple-negative Breast Cancer
Phase 3 Recruiting
416 enrolled
A Clinical Study of Patritumab Deruxtecan to Treat Breast Cancer (MK-1022-016)
Phase 3 Recruiting
1,000 enrolled
OPERA-02
Phase 3 Recruiting
1,000 enrolled
NoLEEta
Phase 3 Recruiting
3,902 enrolled
OPERA-01
Phase 3 Recruiting
510 enrolled
MK-2870-010
Phase 3 Recruiting
1,200 enrolled
Sacituzumab Tirumotecan (MK-2870) Plus Pembrolizumab Versus TPC in TNBC Who Did Not Achieve pCR (MK-2870-012)
Phase 3 Recruiting
1,530 enrolled
TroFuse-011
Phase 3 Recruiting
1,000 enrolled
Dalpiciclib Combined With Endocrine Therapy and Metronomic Capecitabine vs Dalpiciclib Combined With Endocrine Therapy for First-line Treatment
Phase 3 Recruiting
258 enrolled
A Study to Evaluate Efficacy and Safety of Giredestrant Compared With Fulvestrant (Plus a CDK4/6 Inhibitor), in Participants With ER-Positive, HER2-Negative Advanced Breast Cancer Resistant to Adjuvant Endocrine Therapy (pionERA Breast Cancer)
Phase 3 Recruiting
1,050 enrolled
INAVO123
Phase 3 Recruiting
450 enrolled
A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)
Phase 3 Recruiting
920 enrolled
Pembrolizumab vs. Observation in People With Triple-negative Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Pembrolizumab
Phase 3 Recruiting
1,295 enrolled
DEBRA
Phase 3 Recruiting
1,670 enrolled
OFSET
Phase 3 Recruiting
3,960 enrolled
HEAL-ABC
Phase 3 Recruiting
402 enrolled
ReDiscover-2
Phase 3 Recruiting
540 enrolled
Adjuvant WIDER
Phase 3 Recruiting
1,400 enrolled
FourLight-3
Phase 3 Recruiting
1,020 enrolled
A Randomized Trial of Five Fraction Partial Breast Irradiation (RAPID2)
Phase 3 Recruiting
910 enrolled
CAPIcorn
Phase 3 Recruiting
250 enrolled
IBI354 With or Without Pertuzumab Versus Taxane, Trastuzumab and Pertuzumab in HER2-positive Metastatic Breast Cancer
Phase 3 Recruiting
540 enrolled
POWER II
Phase 3 Recruiting
354 enrolled
OLIGAMI
Phase 3 Recruiting
340 enrolled
Trastuzumab Deruxtecan (T-DXd) in Patients Who Have Hormone Receptor-negative and Hormone Receptor-positive HER2-low or HER2 IHC 0 Metastatic Breast Cancer
Phase 3 Recruiting
250 enrolled
ShortStop-HER2: 12 Months vs. 6 Months of HER2-targeted Medications for People With HER2+ Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Trastuzumab
Phase 3 Recruiting
1,524 enrolled
TQB2930 Injection for the Treatment of HER2-positive Advanced Breast Cancer
Phase 3 Recruiting
416 enrolled
OFOBA
Phase 3 Recruiting
158 enrolled
SBRT Combined With PD-1 Inhibitor and Chemotherapy in Early-stage TNBC
Phase 3 Recruiting
318 enrolled
A Trial of SHR-A1811 Compared to Other Antitumor Therapies as Neoadjuvant Treatments in Early-stage or Locally Advanced HER2-positive Breast Cancer
Phase 3 Recruiting
740 enrolled
A Study of SKB264 Versus Investigator's Choice Chemotherapy in Patients With Unresectable Recurrent or Metastatic Triple-Negative Breast Cancer
Phase 3 Recruiting
524 enrolled
ELAINEIII
Phase 3 Recruiting
500 enrolled
CHORD
Phase 3 Recruiting
182 enrolled
Metformin for the Treatment of Insulin Resistance in Women With Stage I-III Breast Cancer Completing Chemotherapy
Phase 3 Recruiting
200 enrolled
A Study of BL-M07D1 Versus T-DM1 in the Adjuvant Treatment of HER2-positive Breast Cancer With Residual Invasive Cancer After Neoadjuvant Therapy
Phase 3 Recruiting
1,450 enrolled
A Study of BL-M07D1 Versus Investigator's Choice of Chemotherapy in Patients With HER2-low Recurrent/Metastatic Breast Cancer
Phase 3 Recruiting
566 enrolled
CDK4/6 Inhibitors Combined With Standard Adjuvant Endocrine Therapy in High-Risk, HR+/HER2+ Early Breast Cancer Patients(CHESS)
Phase 3 Recruiting
1,903 enrolled
Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)
Phase 3 Recruiting
1,514 enrolled
Testing Longer Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With Cancer That Has Spread to the Brain
Phase 3 Recruiting
269 enrolled
Testing Proton Craniospinal Radiation Therapy Versus the Usual Radiation Therapy for Leptomeningeal Metastasis, RADIATE-LM Trial
Phase 3 Recruiting
115 enrolled
TAILOR RT
Phase 3 Recruiting
2,140 enrolled
CAPItrue
Phase 3 Recruiting
300 enrolled
BRIA-ABC
Phase 3 Recruiting
404 enrolled
A Randomised, Open-label, Multicentre Phase III Clinical Study to Evaluate the Efficacy and Safety of JS105 Combined With Dalpiciclib and Fulvestrant Compared With Dalpiciclib and Fulvestrant in Patients With PIK3CA-mutated, HR-positive, HER2-negative Recurrent or Metastatic Breast Cancer.
Phase 3 Recruiting
312 enrolled
Trial Of PreoperAtive Radiation (TOPAz): A Randomized Trial Comparing Hypofractionated Versus Conventionally Fractionated Preoperative Radiation Followed by Mastectomy With Immediate Autologous Breast Reconstruction With Integrated Nanomechanical Biomarker Evaluation
Phase 3 Recruiting
126 enrolled
ECLECTIC
Phase 3 Recruiting
300 enrolled
A Clinical Trial of SHR-A1811 in the Treatment of Triple-negative Breast Cancer
Phase 3 Recruiting
400 enrolled