Clinical Trials Browser

Terminated × NIH × Breast × Clear all

NCT05554354 2026-03-03

Testing the Use of Fulvestrant and Binimetinib Targeted Treatment for NF1 Mutation in Hormone Receptor-Positive Metastatic Breast Cancer (A ComboMATCH Treatment Trial)

Phase 2 Terminated

Anatomic Stage IV Breast Cancer AJCC v8

NCT05035407 2025-12-02

T Cell Receptor Gene Therapy Targeting KK-LC-1 for Gastric, Breast, Cervical, Lung and Other KK-LC-1 Positive Epithelial Cancers

Phase 1 Terminated

36 enrolled 7 charts

Carcinoma, Neoplasm Metastasis, Triple Negative Breast Neoplasms

NCT05198843 2025-10-03

Testing an Omega-3 Fatty Acid-Based Anti-Cancer Therapy for Patients With Triple-Negative Inflammatory Breast Cancer That Has Spread to Other Parts of the Body

Phase 1/2 Terminated

1 enrolled 5 charts

Anatomic Stage IV Breast Cancer AJCC v8

NCT01231932 2025-06-19

Characterizing Fatigue Experienced by Cancer Patients Receiving Primary Treatment and Cancer Survivors

BreastGenitourinary

Breast Neoplasms, Fatigue, Neoplasms, Prostatic Neoplasms

NCT00520975 2025-03-28

Bevacizumab in Treating Patients With Metastatic Breast Cancer That Overexpresses HER-2/NEU

Phase 3 Terminated

96 enrolled 16 charts

Breast Neoplasms

NCT01217411 2024-11-19

RO4929097 and Whole-Brain Radiation Therapy or Stereotactic Radiosurgery in Treating Patients With Brain Metastases From Breast Cancer

Phase 1/2 Terminated

5 enrolled 6 charts

BreastCNSDermatologicThoracic

Brain Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Melanoma, Breast Neoplasms, Male, Small Cell Lung Carcinoma

NCT02876640 2024-06-18

Retinoid 9cUAB30 in Producing a Biologic Effect in Patients With Early Stage Breast Cancer

Phase 1 Terminated

27 enrolled 21 charts

Carcinoma, Intraductal, Noninfiltrating

NCT00019643 2023-10-31

Factors Affecting Weight Gain in Women Receiving Adjuvant Chemotherapy for Breast Cancer

Breast Neoplasms, Depression, Neoplasms, Recurrence, Suicide

NCT03190967 2023-10-11

T-DM1 Alone Versus T-DM1 and Metronomic Temozolomide in Secondary Prevention of HER2-Positive Breast Cancer Brain Metastases Following Stereotactic Radiosurgery

Phase 1/2 Terminated

12 enrolled 16 charts

Brain Neoplasms, Breast Neoplasms

NCT02474173 2022-11-04

Onalespib and Paclitaxel in Treating Patients With Advanced Triple Negative Breast Cancer

Phase 1 Terminated

Breast Neoplasms, Triple Negative Breast Neoplasms

NCT02203513 2022-09-10

A Phase II Single Arm Pilot Study of the Chk1/2 Inhibitor (LY2606368) in BRCA1/2 Mutation Associated Breast or Ovarian Cancer, Triple Negative Breast Cancer, High Grade Serous Ovarian Cancer, and Metastatic Castrate-Resistant Prostate Cancer

Phase 2 Terminated

111 enrolled 15 charts

BreastGenitourinaryGynecologic

Breast Neoplasms, Ovarian Neoplasms, Prostatic Neoplasms, Hereditary Breast and Ovarian Cancer Syndrome

NCT04296942 2022-01-11

BN-Brachyury, Entinostat, Adotrastuzumab Emtansine and M7824 in Advanced Stage Breast Cancer (BrEAsT)

Phase 1 Terminated

1 enrolled 10 charts

Breast Neoplasms, Triple Negative Breast Neoplasms

NCT03407040 2021-11-10

Generation of Cancer Antigen-Specific T-cells From Human Induced Pluripotent Stem Cells (iPSC) for Research and Potential FutureTherapy

BreastDermatologicGastrointestinalThoracic

Breast Neoplasms, Gastrointestinal Neoplasms, Lung Neoplasms, Melanoma, Neoplasms, Pancreatic Neoplasms

NCT01479348 2020-06-02

Imaging Study for FdCyd and THU Cancer Treatment

Phase EARLY_PHASE1 Terminated

5 enrolled 12 charts

BreastGenitourinaryHead & NeckThoracic

Urinary Bladder Neoplasms, Breast Neoplasms, Head and Neck Neoplasms, Lung Neoplasms, Neoplasms

NCT01624090 2019-12-30

Mithramycin for Lung, Esophagus, and Other Chest Cancers

Phase 2 Terminated

16 enrolled 13 charts

BreastGastrointestinalOther solid neoplasmThoracic

Breast Neoplasms, Esophageal Neoplasms, Gastrointestinal Neoplasms, Lung Neoplasms, Mesothelioma

NCT00005655 2019-12-17

Combination Therapy of Interleukin-12 and Interleukin-2 to Treat Advanced Cancer

Phase 1 Terminated

BreastGenitourinarySarcomaThoracic

Breast Neoplasms, Kidney Neoplasms, Lung Neoplasms, Neoplasms, Neovascularization, Pathologic, Sarcoma

NCT01086696 2019-12-17

A Pilot Study of F-18 Paclitaxel (FPAC) PET for Evaluating Drug Delivery of Solid Tumors in Breast, Lung, Renal, and Adrenal Cancers

Phase EARLY_PHASE1 Terminated

BreastEndocrineGenitourinaryThoracic

Adrenal Gland Neoplasms, Breast Neoplasms, Kidney Neoplasms, Lung Neoplasms

NCT00923052 2019-12-16

The Natural History of Solid Organ Cancer Stem Cells (SOCSC)

BreastGastrointestinal

Breast Neoplasms, Liver Neoplasms, Neoplasms, Stomach Neoplasms, Colorectal Neoplasms

NCT03300843 2019-12-13

Ability of a Dendritic Cell Vaccine to Immunize Melanoma or Epithelial Cancer Patients Against Defined Mutated Neoantigens Expressed by the Autologous Cancer

Phase 2 Terminated

1 enrolled 7 charts

BreastDermatologicGastrointestinalGynecologic

Breast Neoplasms, Gastrointestinal Neoplasms, Melanoma, Ovarian Neoplasms, Pancreatic Neoplasms

NCT01374685 2019-12-03

Family Communication of Hereditary Breast and Ovarian Cancer Risk Among African Americans

BreastGynecologic

Breast Neoplasms, Ovarian Neoplasms

NCT02153905 2019-06-17

T Cell Receptor Immunotherapy Targeting MAGE-A3 for Patients With Metastatic Cancer Who Are HLA-A*01 Positive

Phase 1/2 Terminated

3 enrolled 14 charts

BreastDermatologicGenitourinaryGynecologic

Urinary Bladder Neoplasms, Breast Neoplasms, Uterine Cervical Neoplasms, Kidney Neoplasms, Melanoma, Neoplasm Metastasis

NCT01445054 2019-03-11

111 Indium CHX-A DTPA Trastuzumab (Indium-Herceptin) for Imaging Breast Cancer

Phase EARLY_PHASE1 Terminated

BreastGastrointestinalGenitourinaryThoracic

Breast Neoplasms, Colonic Neoplasms, Lung Neoplasms, Prostatic Neoplasms

NCT00063934 2019-03-05

Oblimersen Plus Doxorubicin and Docetaxel in Treating Patients With Metastatic or Locally Advanced Breast Cancer

Phase 1/2 Terminated

31 enrolled 8 charts

Breast Neoplasms, Breast Neoplasms, Male

NCT01776008 2018-05-08

Akt Inhibitor MK-2206 and Anastrozole With or Without Goserelin Acetate in Treating Patients With Stage II-III Breast Cancer

Phase 2 Terminated

16 enrolled 5 charts

Breast Neoplasms

NCT01319539 2017-08-30

MK2206 in Treating Patients With Stage I, Stage II, or Stage III Breast Cancer

Phase 2 Terminated

12 enrolled 9 charts

Breast Neoplasms, Triple Negative Breast Neoplasms

NCT01151449 2017-04-11

Gamma-secretase/Notch Signalling Pathway Inhibitor RO4929097 in Treating Patients With Advanced, Metastatic, or Recurrent Triple Negative Invasive Breast Cancer

Phase 2 Terminated

6 enrolled 8 charts

Breast Neoplasms, Breast Neoplasms, Male, Triple Negative Breast Neoplasms

NCT00096109 2017-01-16

Tanespimycin in Treating Women With Refractory Locally Advanced or Metastatic Breast Cancer

Phase 2 Terminated

11 enrolled 6 charts

Breast Neoplasms

NCT01339000 2016-06-22

Improving the Immune System With Human IL-7 Vaccine in Older Subjects Who Have Had Chemotherapy

Phase 2 Terminated

1 enrolled 5 charts

BreastGastrointestinalGenitourinary

Urinary Bladder Neoplasms, Breast Neoplasms, Colonic Neoplasms, Colorectal Neoplasms

NCT01238133 2015-09-04

Gamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097, Paclitaxel, and Carboplatin Before Surgery in Treating Patients With Stage II or Stage III Triple-Negative Breast Cancer

Phase 1 Terminated

Breast Neoplasms, Triple Negative Breast Neoplasms

NCT01149356 2015-05-25

RO4929097 And Exemestane in Treating Pre- and Postmenopausal Patients With Advanced or Metastatic Breast Cancer

Phase 1 Terminated

Breast Neoplasms, Breast Neoplasms, Male

NCT01071564 2015-04-15

RO4929097 and Vismodegib in Treating Patients With Breast Cancer That is Metastatic or Cannot Be Removed By Surgery

Phase 1 Terminated

Breast Neoplasms, Triple Negative Breast Neoplasms

NCT00450879 2015-03-25

Pazopanib in Treating Patients With Newly Diagnosed or Locally and/or Regionally Recurrent Breast Cancer That Can Be Removed By Surgery

Phase 1 Terminated

Breast Neoplasms, Breast Neoplasms, Male

NCT00132002 2015-03-19

Suberoylanilide Hydroxamic Acid in Treating Patients With Progressive Stage IV Breast Cancer

Phase 2 Terminated

14 enrolled 6 charts

Breast Neoplasms, Breast Neoplasms, Male

NCT00079326 2014-06-02

Trastuzumab and Ixabepilone in Treating Women With HER2-Positive Metastatic Breast Cancer

Phase 2 Terminated

39 enrolled 8 charts

Breast Neoplasms

NCT01233505 2014-04-02

Veliparib, Oxaliplatin, and Capecitabine in Treating Patients With Advanced Solid Tumors

Phase 1 Terminated

BreastGastrointestinalGynecologic

Carcinoma, Ovarian Epithelial, Breast Neoplasms, Colonic Neoplasms, Pancreatic Neoplasms, Rectal Neoplasms, Stomach Neoplasms

NCT00071942 2013-12-11

Vaccine Therapy in Treating Patients With Metastatic Breast Cancer

Phase 1 Terminated

Breast Neoplasms, Breast Neoplasms, Male

NCT01705340 2013-09-30

Akt Inhibitor MK2206, Lapatinib Ditosylate, and Trastuzumab in Treating Patients With Locally Advanced or Metastatic HER2-Positive Breast , Gastric, or Gastroesophageal Cancer That Cannot Be Removed By Surgery

Phase 1 Terminated

BreastGastrointestinal

Breast Neoplasms, Esophageal Neoplasms, Stomach Neoplasms, Breast Neoplasms, Male

NCT00674557 2013-07-10

Exemestane With or Without ATN-224 in Treating Postmenopausal Women With Recurrent or Advanced Breast Cancer

Phase 2 Terminated

Breast Neoplasms

NCT00896467 2013-07-10

Psychological and Emotional Impact in Patients Undergoing Treatment For Metastatic Cancer Either in a Clinical Trial or as Standard Off-Trial Therapy

BreastGastrointestinalGenitourinaryThoracic

Anus Neoplasms, Anxiety Disorders, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Depression, Esophageal Neoplasms, Gallbladder Neoplasms, Kidney Neoplasms, Liver Neoplasms, Lung Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms

NCT00937482 2013-03-08

Cediranib Maleate and Whole Brain Radiation Therapy in Patients With Brain Metastases From Non-Small Cell Lung Cancer

Phase 1 Terminated

BreastCNSDermatologicGastrointestinalGenitourinaryThoracic

Brain Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Colonic Neoplasms, Melanoma, Rectal Neoplasms, Breast Neoplasms, Male

NCT00039455 2013-02-01

Trastuzumab and Flavopiridol in Treating Patients With Metastatic Breast Cancer

Phase 1 Terminated

Breast Neoplasms, Breast Neoplasms, Male

NCT00095888 2013-01-16

3-AP and Gemcitabine in Treating Patients With Refractory Metastatic Breast Cancer

Phase 2 Terminated

Breast Neoplasms, Breast Neoplasms, Male

NCT00048893 2012-04-13

Vaccine and Chemotherapy for Previously Untreated Metastatic Breast Cancer

Phase 1/2 Terminated

37 enrolled 9 charts

Breast Neoplasms, Neoplasm Metastasis