Clinical Trials

56 enrolled

Breast Neoplasms

NCT04789668 2026-03-18

Bintrafusp Alfa and Pimasertib for the Treatment of Patients With Brain Metastases

BreastCNSDermatologicOther hematologic neoplasmThoracic

8 enrolled 13 charts

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Hematologic Neoplasms, Triple Negative Breast Neoplasms

NCT06038539 2026-03-13

Efficacy and Safety of the Proposed Biosimilar Pertuzumab (PERT-IJS) Versus EU-Perjeta® Along With Trastuzumab and Chemotherapy (Carboplatin and Docetaxel) as Neoadjuvant Treatment in Chemotherapy naïve Patients With Early Stage or Locally Advanced HR Negative and HER2 Positive Breast Cancer

Phase 3 Terminated

55 enrolled

HR Negative HER2 Positive Early Breast Cancer or Locally Advanced Breast Cancer Patients

NCT04796324 2026-03-12

Anti-tumor Effect of Ixabepilone in Metastatic Breast Cancer (mBC) Selected by the Ixabepilone DRP.

13 enrolled 8 charts

Breast Neoplasms

NCT05744375 2026-03-12

TRANSCENDER

2 enrolled 10 charts

Breast Neoplasms

NCT05554354 2026-03-03

Testing the Use of Fulvestrant and Binimetinib Targeted Treatment for NF1 Mutation in Hormone Receptor-Positive Metastatic Breast Cancer (A ComboMATCH Treatment Trial)

1 enrolled

Anatomic Stage IV Breast Cancer AJCC v8

NCT06315296 2026-03-03

An Interactive Time-Restricted Diet Intervention (txt4fasting) for Reducing Neurocognitive Decline and Improving Survival in Patients With Brain Metastases From Breast or Lung Cancer

1 enrolled

BreastCNSThoracic

Brain Neoplasms, Breast Neoplasms, Lung Neoplasms

NCT06617455 2026-03-02

VEnT

9 enrolled

Carcinoma, Intraductal, Noninfiltrating

NCT06162663 2026-02-27

Double-blind Randomized Controlled Trial Comparing Suvorexant 20 mg to Placebo for Treatment of Insomnia in Cancer Survivors

Phase 4 Terminated

5 enrolled

Breast Neoplasms, Sleep Initiation and Maintenance Disorders

NCT03801369 2026-02-25

AMTEC IIT: Phase 2 Multiarm Study in TNBC

24 enrolled 16 charts

Triple Negative Breast Neoplasms

NCT06171789 2026-02-25

PRO1107 in Patients With Advanced Solid Tumors

BreastGenitourinaryGynecologicThoracic

33 enrolled

Carcinoma, Non-Small-Cell Lung, Carcinoma, Transitional Cell, Ovarian Neoplasms, Endometrial Neoplasms, Triple Negative Breast Neoplasms

NCT03428581 2026-02-24

Preventing Lymphedema in Axillary Lymph Node Dissection

264 enrolled

BreastDermatologic

Breast Neoplasms, Lymphedema, Melanoma

NCT04059484 2026-02-24

AMEERA-3

367 enrolled 30 charts

Breast Cancer Metastatic

NCT05269160 2026-02-17

Topical Dermaprazole for Radiation Dermatitis in Breast Cancer Patients (TOPAZ)

3 enrolled 8 charts

Breast Neoplasms, Radiodermatitis

NCT03101748 2026-02-12

Neratinib and Paclitaxel With or Without Pertuzumab and Trastuzumab Before Combination Chemotherapy in Treating Patients With Metastatic or Locally Advanced Breast Cancer

34 enrolled 15 charts

Breast Neoplasms, Inflammatory Breast Neoplasms

NCT03237572 2026-02-09

Breast-48

13 enrolled 10 charts

Breast Neoplasms

NCT04990895 2026-02-05

A Research Study to Collect Patient Reported Outcomes Using Electronic Surveys

Phase EARLY_PHASE1 Terminated

8 enrolled

BreastGastrointestinal

Breast Neoplasms, Colorectal Neoplasms

NCT04044872 2026-02-02

Hyperpolarized Carbon 13-Based Metabolic Imaging to Detect Radiation-Induced Cardiotoxicity

3 enrolled

Unilateral Breast Neoplasms, Cardiotoxicity

NCT04095689 2026-01-23

INTEGRAL

8 enrolled 10 charts

Triple Negative Breast Neoplasms

NCT04570956 2026-01-23

Oral Tamoxifen vs. TamGel vs. Control in Women With Atypical Hyperplasia, Lobular Carcinoma In Situ, or Increased Breast Cancer Risk

65 enrolled

Breast Carcinoma In Situ, Breast Neoplasms

NCT03289039 2026-01-22

Neratinib +/- Fulvestrant in HER2+, ER+ Metastatic Breast Cancer

21 enrolled 15 charts

Breast Neoplasms

NCT03765983 2026-01-22

GDC-0084 in Combination With Trastuzumab for Patients With HER2-Positive Breast Cancer Brain Metastases

17 enrolled

Breast Neoplasms

NCT05070247 2026-01-22

A Study of TAK-500 With or Without Pembrolizumab in Adults With Select Locally Advanced or Metastatic Solid Tumors

BreastGastrointestinalGenitourinaryHead & NeckOther solid neoplasmThoracic

61 enrolled 29 charts

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Esophageal Neoplasms, Kidney Neoplasms, Liver Neoplasms, Mesothelioma, Nasopharyngeal Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms

NCT04260802 2026-01-12

A Study to Evaluate the Safety and Pharmacokinetics of OC-001 in Patients With Locally Advanced or Metastatic Cancers

BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckSarcomaThoracic

73 enrolled

Squamous Cell Carcinoma of Head and Neck, Urinary Bladder Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Squamous Cell, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Carcinoma, Hepatocellular, Neoplasm Metastasis, Neoplasms, Ovarian Neoplasms, Sarcoma, Stomach Neoplasms, Carcinoma, Merkel Cell, Triple Negative Breast Neoplasms

NCT05194072 2026-01-09

A Study of Felmetatug Vedotin/SGN-B7H4V in Advanced Solid Tumors

BreastGastrointestinalGynecologicThoracic

250 enrolled

Carcinoma, Non-Small-Cell Lung, Carcinoma, Adenoid Cystic, Fallopian Tube Neoplasms, Gallbladder Neoplasms, Ovarian Neoplasms, Peritoneal Neoplasms, Endometrial Neoplasms, Cholangiocarcinoma, Triple Negative Breast Neoplasms

NCT03746431 2026-01-07

A Phase 1 Study of [225Ac]-FPI-1434 Injection

BreastDermatologicEndocrineGynecologicHead & Neck

78 enrolled

Squamous Cell Carcinoma of Head and Neck, Uveal Melanoma, Breast Neoplasms, Uterine Cervical Neoplasms, Ovarian Neoplasms, Endometrial Neoplasms, Adrenocortical Carcinoma, Triple Negative Breast Neoplasms

NCT04578106 2026-01-06

ELPIS

5 enrolled 7 charts

Breast Neoplasms

NCT04986852 2025-12-30

Olinvacimab With Pembrolizumab in Patients With mTNBC

19 enrolled

Triple Negative Breast Neoplasms

NCT03225547 2025-12-23

Study of Pembrolizumab and Mifepristone in Patients With Advanced HER2-negative Breast Cancer

24 enrolled

Breast Neoplasms, Triple Negative Breast Neoplasms

NCT03955640 2025-12-22

Hyperthermia and Olaparib in Treating Breast Cancer Patients With Chest Wall Recurrences

3 enrolled

Breast Neoplasms

NCT04113863 2025-12-18

ATRA

76 enrolled

Breast Neoplasm Female

NCT04534010 2025-12-17

Decellularized, Whole Donor Nipple-Areola Complex Reconstruction Grafts

6 enrolled 9 charts

Breast Neoplasms

NCT05583110 2025-12-10

TrasTUCAN

13 enrolled

Breast Neoplasms

NCT02688803 2025-12-04

OTT15-04

Phase 4 Terminated

2 enrolled 4 charts

Breast Neoplasms

NCT05035407 2025-12-02

T Cell Receptor Gene Therapy Targeting KK-LC-1 for Gastric, Breast, Cervical, Lung and Other KK-LC-1 Positive Epithelial Cancers

36 enrolled 7 charts

Carcinoma, Neoplasm Metastasis, Triple Negative Breast Neoplasms

NCT05180006 2025-12-01

BIS-Program

33 enrolled

Breast Neoplasms, Triple Negative Breast Neoplasms

NCT03284957 2025-11-24

AMEERA-1

136 enrolled 60 charts

Breast Neoplasms

NCT04725331 2025-11-21

A Clinical Trial Assessing BT-001 Alone and in Combination With Pembrolizumab in Metastatic or Advanced Solid Tumors

BreastDermatologicSarcomaThoracic

31 enrolled

Carcinoma, Non-Small-Cell Lung, Melanoma, Neoplasm Metastasis, Sarcoma, Vaccinia, Carcinoma, Merkel Cell, Triple Negative Breast Neoplasms

NCT05954143 2025-11-20

Trial of BDC-1001 +/- Pertuzumab in Subjects With HER2-Positive Metastatic Breast Cancer

11 enrolled 13 charts

Breast Neoplasms

NCT06052852 2025-11-17

Study of BDC-3042 as Single Agent and in Combination With Cemiplimab in Patients With Advanced Malignancies

BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

17 enrolled

Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Head and Neck Neoplasms, Melanoma, Ovarian Neoplasms, Colorectal Neoplasms, Triple Negative Breast Neoplasms

NCT02936102 2025-11-14

A Study of FAZ053 Single Agent and in Combination With PDR001 in Patients With Advanced Malignancies.

154 enrolled

BreastSarcoma

Chordoma, Sarcoma, Alveolar Soft Part, Triple Negative Breast Neoplasms

NCT03519178 2025-11-14

A Study of PF-06873600 in People With Cancer

155 enrolled 44 charts

BreastGynecologic

Carcinoma, Ovarian Epithelial, Breast Neoplasms, Fallopian Tube Neoplasms, Ovarian Neoplasms, Breast Neoplasms, Male, Triple Negative Breast Neoplasms

NCT04024436 2025-11-13

A Study of TAS-120 in Patients With Metastatic Breast Cancer

64 enrolled 21 charts

Breast Neoplasms

NCT03979508 2025-11-12

Abemaciclib in Treating Patients With Surgically Resectable, Chemotherapy Resistant, Triple Negative Breast Cancer

26 enrolled

Breast Carcinoma In Situ, Carcinoma, Intraductal, Noninfiltrating, Fibrocystic Breast Disease, Triple Negative Breast Neoplasms

NCT04504916 2025-11-10

MK-2140-002

102 enrolled 36 charts

BreastGastrointestinal

Pancreatic Neoplasms, Stomach Neoplasms, Triple Negative Breast Neoplasms

NCT00556907 2025-11-06

Targeted Intra-Operative Radiotherapy for the Management of Ductal Carcinoma In-Situ of the Breast

36 enrolled 6 charts

Breast Neoplasms, Carcinoma, Intraductal, Noninfiltrating

NCT04958785 2025-11-04

ELEVATE TNBC

92 enrolled 27 charts

Triple Negative Breast Neoplasms

NCT05169437 2025-10-29

PAVO

BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

22 enrolled 17 charts

Breast Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Head and Neck Neoplasms, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Pancreatic Neoplasms, Urologic Neoplasms, Endometrial Neoplasms

NCT02711137 2025-10-21

Open-Label Safety and Tolerability Study of INCB057643 in Subjects With Advanced Malignancies