Clinical Trials

CNSGastrointestinalThoracic

134 enrolled

Colonic Neoplasms, Glioblastoma, Lung Neoplasms, Neoplasms, Pancreatic Neoplasms, Disease Progression

NCT07480941 2026-03-18

DUAL-CAR-NK-GB

36 enrolled

Glioblastoma, Glioma

NCT06926075 2026-03-17

ADVICE

BreastCNSDermatologicGastrointestinalGenitourinaryGynecologicThoracic

80 enrolled

Breast Neoplasms, Glioblastoma, Lung Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Skin Neoplasms

NCT05109728 2026-03-16

A Dose Finding Study of [177Lu]Lu-DOTA-TATE in Newly Diagnosed Glioblastoma in Combination With Standard of Care and in Recurrent Glioblastoma as a Single Agent.

Phase 1 Active not recruiting

65 enrolled

Glioblastoma

NCT06556563 2026-03-13

EF-41

741 enrolled

Glioblastoma

NCT07100730 2026-03-12

IPAX BrIGHT

50 enrolled

Brain Neoplasms, Glioblastoma, Neoplasm Recurrence, Local, Neoplasms, Central Nervous System Neoplasms

NCT07297212 2026-03-12

A Clinical Trial Testing the Safety of the Investigational Drug Pumitamig (BNT327) and How Well it Works in Patients With Recurrent Glioblastoma

Phase 2 Recruiting

75 enrolled

Phase 1 Not yet recruiting

Brain Neoplasms, Glioblastoma

NCT07464925 2026-03-11

A Phase 1 Safety and Dose Finding Study of GLIX1 in Adults With Recurrent or Progressive High-grade Glioma

30 enrolled

Phase 1 Not yet recruiting

Glioblastoma, Glioma

NCT07455045 2026-03-06

A Phase I Study of FZ-AD005 in Patients With High-Grade Glioma (HGG)

40 enrolled

Glioblastoma, Glioma

NCT05303519 2026-03-05

SIGMA

365 enrolled

CNSLymphoid

Astrocytoma, Glioblastoma, Glioma, Lymphoma, Follicular, Oligodendroglioma

NCT07195591 2026-03-04

BRIDGES

766 enrolled

Phase 1/2 Not yet recruiting

Glioblastoma, Neoplasms

NCT07346144 2026-03-04

ADePT

68 enrolled

Glioblastoma

NCT04238819 2026-03-02

A Study of Abemaciclib (LY2835219) in Combination With Other Anti-Cancer Treatments in Children and Young Adult Participants With Solid Tumors, Including Neuroblastoma

Phase 1/2 Completed

47 enrolled 36 charts

CNSSarcoma

Diffuse Intrinsic Pontine Glioma, Brain Neoplasms, Ependymoma, Glioblastoma, Glioma, Medulloblastoma, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Ewing, Osteosarcoma, Rhabdoid Tumor

NCT05303467 2026-03-02

FRONTIER

36 enrolled

Glioblastoma

NCT06047379 2026-03-02

Safety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain Metastasis

CNSDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

134 enrolled

Squamous Cell Carcinoma of Head and Neck, Esophageal Squamous Cell Carcinoma, Astrocytoma, Brain Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Squamous Cell, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Esophageal Neoplasms, Glioblastoma, Melanoma, Stomach Neoplasms, Colorectal Neoplasms, Carcinoma, Merkel Cell, Central Nervous System Neoplasms, Small Cell Lung Carcinoma

NCT05765812 2026-02-27

A Study of Debio 0123 in Combination With Temozolomide in Adult Participants With Recurrent or Progressive Glioblastoma and of Debio 0123 in Combination With Temozolomide and Radiotherapy in Adult Participants With Newly Diagnosed Glioblastoma

116 enrolled

CNSLymphoid

Astrocytoma, Glioblastoma, Lymphoma, Follicular

NCT01068782 2026-02-25

Multiple Doses and Regimens of Cabozantinib in Subjects With Grade IV Astrocytic Tumors in First or Second Relapse

Phase 2 Terminated

19 enrolled 10 charts

Phase 1/2 Not yet recruiting

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma

NCT07431216 2026-02-24

A Phase 1b/2a Study to Evaluate the Safety, Pharmacokinetics, and Objective Response of STAR-001 (LP-184) in Combination With Spironolactone in Supratentorial Glioblastoma at First Progression

68 enrolled

Glioblastoma

NCT06805305 2026-02-23

DOC1021 Dendritic Cell Immunotherapy for Treatment of Newly Diagnosed Adult Glioblastoma (GBM)

Phase 2 Recruiting

180 enrolled

Glioblastoma

NCT06641908 2026-02-18

Anti-GD2 ADC M3554 in Advanced Solid Tumors

52 enrolled

CNSSarcoma

Glioblastoma, Sarcoma

NCT07417774 2026-02-18

RESTORE LB

Enrolling by invitation

40 enrolled

Phase 4 Active not recruiting

Glioblastoma

NCT03975829 2026-02-13

Pediatric Long-Term Follow-up and Rollover Study

163 enrolled

CNSMyeloid

Astrocytoma, Ganglioneuroma, Glioblastoma, Glioma, Histiocytosis, Langerhans-Cell, Neuroblastoma, Neurofibromatosis 1, Oligodendroglioma, Ganglioglioma, Neurocytoma, Neurofibroma, Plexiform

NCT06061809 2026-02-12

N-803 and PD-L1 t-haNK Combined With Bevacizumab for Recurrent or Progressive Glioblastoma

Phase 2 Recruiting

34 enrolled

Phase 2 Active not recruiting

Glioblastoma

NCT04485949 2026-02-10

A Phase 2b Clinical Study With a Combination Immunotherapy in Newly Diagnosed Patients With Glioblastoma

93 enrolled

Glioblastoma

NCT07042620 2026-02-10

A Study to Test a New Fluid to Improve the Quality of Images Obtained by Using Sound Waves (Ultrasound) During Surgery

Phase NA Recruiting

15 enrolled

Glioblastoma, Glioma

NCT03866109 2026-02-09

TEM-GBM

27 enrolled

Glioblastoma

NCT04478279 2026-02-09

A Phase 1-2 Study of ST101 in Patients With Advanced Solid Tumors

BreastCNSDermatologicGenitourinary

125 enrolled

Brain Neoplasms, Breast Neoplasms, Glioblastoma, Melanoma, Prostatic Neoplasms

NCT05635734 2026-02-05

Azeliragon and Chemoradiotherapy in Newly Diagnosed Glioblastoma

18 enrolled

Phase 1 Active not recruiting

Glioblastoma

NCT05739942 2026-02-03

Dose Finding Study of [177Lu]Lu-NeoB in Newly Diagnosed Glioblastoma and in Recurrent Glioblastoma

40 enrolled

Glioblastoma

NCT06810544 2026-02-02

Safety and Tolerability of TNG456 Alone and in Combination With Abemaciclib in Patients With Solid Tumors With MTAP Loss

Phase 1 Active not recruiting

191 enrolled

CNSThoracic

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung, Glioblastoma, Glioma, Lung Neoplasms

NCT05627323 2026-01-29

CAR T Cells in Patients With MMP2+ Recurrent or Progressive Glioblastoma

42 enrolled

CNSDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

Glioblastoma

NCT04566393 2026-01-28

Expanded Access to Ulixertinib (BVD-523) in Patients With Advanced MAPK Pathway-Altered Malignancies

Available

Urinary Bladder Neoplasms, Carcinoma, Non-Small-Cell Lung, Esophageal Neoplasms, Glioblastoma, Head and Neck Neoplasms, Carcinoma, Hepatocellular, Melanoma, Ovarian Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Thyroid Neoplasms, Colorectal Neoplasms, Cholangiocarcinoma

NCT04752813 2026-01-26

A Study of BPM31510 With Vitamin K1 in Subjects With Newly Diagnosed Glioblastoma (GB)

Phase 2 Active not recruiting

50 enrolled

Phase 2 Not yet recruiting

Glioblastoma

NCT07356973 2026-01-26

OPTICAL

147 enrolled

Phase 2 Not yet recruiting

Glioblastoma

NCT07365280 2026-01-26

Neoantigen-Pulsed Autologous Dendritic Cell Vaccine Combined With Temozolomide for Newly Diagnosed Glioblastoma

78 enrolled

Glioblastoma

NCT07366892 2026-01-26

IMED-GLOW400

Not yet recruiting

37 enrolled

Glioblastoma, Glioma

NCT05450744 2026-01-21

IPAX-2

12 enrolled

Glioblastoma, Neoplasms

NCT04417088 2026-01-20

Exablate Blood-Brain Barrier Disruption for the Treatment of rGBM in Subjects Undergoing Carboplatin Monotherapy

Phase 1/2 Completed

28 enrolled

Glioblastoma

NCT04440358 2026-01-20

Exablate Blood-Brain Barrier Disruption With Carboplatin for the Treatment of rGBM

Phase 1/2 Completed

13 enrolled

Phase 2/3 Active not recruiting

Glioblastoma

NCT06105619 2026-01-20

A Study of PLB1001 Enteric Capsules in the Treatment of sGBM/IDH Mutant Glioblastoma Patients With the ZM Fusion Gene (FUGEN).

84 enrolled

Phase 2/3 Not yet recruiting

Glioblastoma

NCT07349693 2026-01-20

Cerebraca-02/3

175 enrolled

Glioblastoma

NCT05283330 2026-01-15

Safety and Tolerability of ²¹²Pb-DOTAM-GRPR1 in Adult Subjects With Recurrent or Metastatic GRPR-expressing Tumors

BreastCNSGastrointestinalGynecologicThoracic

48 enrolled

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Uterine Cervical Neoplasms, Colonic Neoplasms, Glioblastoma

NCT02586857 2026-01-12

A Phase 1b/2, Multicenter, Open-label Study of ACP-196 in Subjects With Recurrent Glioblastoma Multiforme (GBM)

CNSLymphoidOther hematologic neoplasm

24 enrolled 10 charts

Glioblastoma, Leukemia, Lymphocytic, Chronic, B-Cell

NCT06717295 2026-01-02

CCANED-CIPHER

Recruiting

6,000 enrolled

CNSGastrointestinalGenitourinaryGynecologicThoracic

Pancreatic cancer, adult, Carcinoma, Non-Small-Cell Lung, Glioblastoma, Carcinoma, Hepatocellular, Lung Neoplasms, Neoplasms, Ovarian Neoplasms, Prostatic Neoplasms, Colorectal Neoplasms

NCT07093814 2026-01-02

A Study of VRT106 for Injection in Patients With Recurrent/Progressive Glioblastoma

42 enrolled

Glioblastoma

NCT05267106 2025-12-30

FIGHT-209

Phase 2 Terminated

83 enrolled 18 charts