NCT04655404 2026-03-18
A Pilot Study of Larotrectinib for Newly-Diagnosed High-Grade Glioma With NTRK Fusion
Nationwide Children's Hospital
Phase EARLY_PHASE1 Recruiting
Clinical Trials
61 trialsNCT06333899 2026-03-12
Lorlatinib for Newly-Diagnosed High-Grade Glioma With ROS or ALK Fusion
Nationwide Children's Hospital
Phase EARLY_PHASE1 Recruiting
NCT05076513 2026-03-09
Trial of Niraparib in Participants With Newly-diagnosed Glioblastoma and Recurrent Glioma
St. Joseph's Hospital and Medical Center, Phoenix
Phase EARLY_PHASE1 Active not recruiting
NCT05182905 2026-03-09
AZD1390 in Recurrent and Newly Diagnosed WHO Grade 4 Glioma Patients
St. Joseph's Hospital and Medical Center, Phoenix
Phase EARLY_PHASE1 Active not recruiting
NCT04391595 2026-03-06
LY3214996 Plus Abemaciclib in Recurrent Glioblastoma Patients
St. Joseph's Hospital and Medical Center, Phoenix
Phase EARLY_PHASE1 Completed
NCT05804227 2026-02-27
Window-of-Opportunity Trial of Ulixertinib for MAPK-Activated Gliomas
M.D. Anderson Cancer Center
Phase EARLY_PHASE1 Recruiting
NCT07210632 2026-02-27
Window Trial of Fluorescently Labeled Nivolumab-IRDye800 (Nivo800) in High Grade Glioma (HGG)
Vanderbilt-Ingram Cancer Center
Phase EARLY_PHASE1 Not yet recruiting
NCT06636162 2026-02-23
Window of Opportunity Study of DSP-0390 in Gliomas
Washington University School of Medicine
Phase EARLY_PHASE1 Recruiting
NCT05676489 2026-02-20
MeFAMP for Imaging System A Amino Acid Transport in Primary and Metastatic Brain Tumors
University of Alabama at Birmingham
Phase EARLY_PHASE1 Not yet recruiting
NCT05406700 2026-02-09
Niraparib In Recurrent IDH 1/2 Gliomas
Massachusetts General Hospital
Phase EARLY_PHASE1 Active not recruiting
NCT07050836 2026-02-04
Contrast Enhanced Ultrasound in Neurosurgery to Improve Glioma Visualization and Border Demarcation
University of Colorado, Denver
Phase EARLY_PHASE1 Recruiting
NCT07025226 2026-01-26
Senolytics
Mayo Clinic
Phase EARLY_PHASE1 Recruiting
NCT05851378 2026-01-12
Hyperpolarized Carbon-13 Alpha-ketoglutarate Imaging in IDH Mutant Glioma
University of California, San Francisco
Phase EARLY_PHASE1 Recruiting
NCT06829173 2026-01-02
Concurrent XRD-0394 With Radiation Therapy for High Grade Gliomas
NYU Langone Health
Phase EARLY_PHASE1 Recruiting
NCT04943913 2025-12-11
Study of GC101 TIL in Brain Glioma (Soochow2)
Shanghai Juncell Therapeutics
Phase EARLY_PHASE1 Recruiting
NCT05632562 2025-12-11
Multiparametic Metabolic and Hypoxic PET/MRI for Disease Assessment in High Grade Glioma
University of Alabama at Birmingham
Phase EARLY_PHASE1 Recruiting
NCT07077616 2025-12-08
TAMAVAQTM
Biogenea Pharmaceuticals Ltd.
Phase EARLY_PHASE1 Recruiting
NCT05553041 2025-12-04
18F-Fluciclovine PET-MRI in High-grade Glioma
Children's Hospital of Philadelphia
Phase EARLY_PHASE1 Recruiting
NCT05555550 2025-12-04
Evaluation of 18F-Fluciclovine Positron Emission Tomography - Magnetic Resonance Imaging (PET-MRI) in LGG
Children's Hospital of Philadelphia
Phase EARLY_PHASE1 Recruiting
NCT06209567 2025-12-03
A Study of 68Ga-PSMA-11 PET Scans in People With Brain Tumors
Memorial Sloan Kettering Cancer Center
Phase EARLY_PHASE1 Active not recruiting
NCT06072586 2025-11-20
A Phase 0/1 Study of BDTX-1535 in Recurrent High-Grade Glioma (rHGG) and Newly Diagnosed Glioblastoma (nGBM) Participants With EGFR Alterations or Fusions
St. Joseph's Hospital and Medical Center, Phoenix
Phase EARLY_PHASE1 Recruiting
NCT05045027 2025-11-14
Simultaneous Multinuclear Metabolic MRI in Newly Diagnosed or Recurrent Glioma
Jonsson Comprehensive Cancer Center
Phase EARLY_PHASE1 Active not recruiting
NCT05717153 2025-11-04
Intratumoral Extracellular Metabolic Impact of DFMO and AMXT 1501 in Patients With Diffuse or High Grade Glioma
Mayo Clinic
Phase EARLY_PHASE1 Recruiting
NCT04424966 2025-10-24
Infigratinib in Recurrent High-Grade Glioma Patients
St. Joseph's Hospital and Medical Center, Phoenix
Phase EARLY_PHASE1 Terminated
NCT05634707 2025-09-22
Evaluation of Fluoxetine and Cytotoxic Lysosomal Stress in Glioma (FLIRT)
Duke University
Phase EARLY_PHASE1 Active not recruiting
NCT05023551 2025-09-16
Study of DSP-0390 in Patients With Recurrent High-Grade Glioma
Sumitomo Pharma America, Inc.
Phase EARLY_PHASE1 Active not recruiting
NCT01165632 2025-09-02
Fluorine F 18 Fluorodopa-Labeled PET Scan in Planning Surgery and Radiation Therapy in Treating Patients With Newly Diagnosed High- or Low-Grade Malignant Glioma
Mayo Clinic
Phase EARLY_PHASE1 Completed
NCT03893487 2025-07-11
PNOC016
University of California, San Francisco
Phase EARLY_PHASE1 Active not recruiting
NCT03834740 2025-05-30
A Phase 0/I Study of Ribociclib (LEE011) in Combination With Everolimus in Preoperative Recurrent High-Grade Glioma Patients Scheduled for Resection
St. Joseph's Hospital and Medical Center, Phoenix
Phase EARLY_PHASE1 Completed
NCT04559685 2025-03-14
Study of Sonodynamic Therapy in Participants with Recurrent High-Grade Glioma
St. Joseph's Hospital and Medical Center, Phoenix
Phase EARLY_PHASE1 Recruiting
NCT05773326 2025-02-27
Superselective Intra-arterial Cerebral Infusion of Temsirolimus in HGG
St. Joseph's Hospital and Medical Center, Phoenix
Phase EARLY_PHASE1 Recruiting
NCT06828341 2025-02-14
A Single-arm, Open, Exploratory Clinical Study of Allogeneic CAR-T Cells in the Treatment of Relapsed/Refractory Brain Gliomas With Positive CD70 Expression
Jinling Hospital, China
Phase EARLY_PHASE1 Recruiting
NCT05473923 2025-02-11
PTCs-based Precision Treatment Strategy on Recurrent High-grade Gliomas
Beijing Tiantan Hospital
Phase EARLY_PHASE1 Active not recruiting
NCT02020720 2025-01-23
18F-DOPA-PET in Planning Surgery in Patients With Gliomas
Mayo Clinic
Phase EARLY_PHASE1 Completed
NCT02901925 2024-12-13
ABY-029
Dartmouth-Hitchcock Medical Center
Phase EARLY_PHASE1 Completed
NCT03796273 2024-09-19
Ketoconazole Before Surgery in Treating Patients With Recurrent Glioma or Breast Cancer Brain Metastases
Wake Forest University Health Sciences
Phase EARLY_PHASE1 Terminated
NCT05977738 2024-08-07
ReDiReCCT-Pita
Erasmus Medical Center
Phase EARLY_PHASE1 Completed
NCT04937413 2024-06-25
The PCSK9i Inhibitor Evolocumab - a Surgical Trial of Pharamcodynamics and Kinetics Evaluation
Duke University
Phase EARLY_PHASE1 Completed
NCT04752267 2024-05-24
18F-FMAU PET/CT and MRI for the Detection of Brain Tumors in Patients With Brain Cancer or Brain Metastases
University of Southern California
Phase EARLY_PHASE1 Completed
NCT06412952 2024-05-14
68Ga-NOTA-RM26 PET/CT in Glioma Patients
Peking Union Medical College Hospital
Phase EARLY_PHASE1 Recruiting
NCT06396481 2024-05-02
CSAγδTBMG
Beijing Tiantan Hospital
Phase EARLY_PHASE1 Not yet recruiting
NCT03763396 2024-03-08
Azoles Targeting Recurrent High Grade Gliomas
University Health Network, Toronto
Phase EARLY_PHASE1 Not yet recruiting
NCT05054400 2023-09-01
Study of Laser Interstitial Thermal Therapy (LITT) Treatment Response Assessment With Fluciclovine PET MR
M.D. Anderson Cancer Center
Phase EARLY_PHASE1 Withdrawn
NCT03927274 2023-05-25
Intratumorally-Administered Topotecan Using Convection-Enhanced Delivery in Patients With Grade III/ IV Glioma
H. Lee Moffitt Cancer Center and Research Institute
Phase EARLY_PHASE1 Terminated
NCT04114370 2022-12-06
FACBC
University of Pittsburgh
Phase EARLY_PHASE1 Completed
NCT05459441 2022-07-15
Efficacy and Safety Evaluation of Percutaneous Ommaya Capsule Injection of Autologous Bi-dimensional Specific T Cells in the Treatment of Glioma and in Combination With Pemetrexed in the Treatment of Brain/Meningeal Metastases
Shanghai Pudong Hospital
Phase EARLY_PHASE1 Unknown
NCT05333588 2022-04-19
The Safety Study of Autologous TILs Therapy for Patients With Glioblastoma Multiforme.
Hebei Senlang Biotechnology Inc., Ltd.
Phase EARLY_PHASE1 Unknown
NCT05061251 2022-01-11
Surgical Window of Opportunity Study of Orally Administered BAY 2402234 in Recurrent Glioma
University of Texas Southwestern Medical Center
Phase EARLY_PHASE1 Withdrawn
NCT03347097 2021-08-25
Adoptive Cell Therapy of Autologous TIL and PD1-TIL Cells for Patients With Glioblastoma Multiforme
Huashan Hospital
Phase EARLY_PHASE1 Unknown
NCT04220892 2020-07-31
Pilot Study of Pembrolizumab Combined With Pemetrexed or Abemaciclib for High Grade Glioma
Saint John's Cancer Institute
Phase EARLY_PHASE1 Withdrawn