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Clinical Trials

1 trials

Recent Start date Enrollment

Gliosarcoma × binimetinib × CNS × Clear all

Phase

Status

Sponsor Class

Study Type

Interventional 1

Sponsor

Cancer Type

Sarcoma 1 CNS 1

Conditions

Melanoma 8 Brain Neoplasms 8 Carcinoma, Non-Small-Cell Lung 3 Neurofibromatosis 1 2 Glioma 2 Thyroid Neoplasms 1 Soft Tissue Neoplasms 1 Peripheral Nervous System Neoplasms 1 Neurofibromatoses 1 Neurofibroma, Plexiform 1 Neurofibroma 1 Neoplasms 1 Neoplasm Metastasis 1 Hereditary Sensory and Autonomic Neuropathies 1 Gliosarcoma 1 Glioblastoma 1 Craniopharyngioma 1 Colorectal Neoplasms 1 Central Nervous System Neoplasms 1 Brain Diseases 1 Astrocytoma 1

Interventions

Temozolomide 120 Radiotherapy 80 Bevacizumab 41 Radiation 29 Carmustine 26 Irinotecan 21 Erlotinib Hydrochloride 21 Magnetic Resonance Spectroscopy 18 Chemotherapy, Adjuvant 17 Surgical Procedures, Operative 13 O(6)-benzylguanine 13 Carboplatin 13 sargramostim 12 Radiotherapy, Intensity-Modulated 11 Radiotherapy, Conformal 11 Imatinib Mesylate 9 Thalidomide 8 motexafin gadolinium 7 Radiosurgery 7 Procarbazine 7 Gene Expression Profiling 7 Gefitinib 7 Filgrastim 7 Drug Therapy 7 Cyclophosphamide 7 pembrolizumab 6 cediranib 6 Vorinostat 6 Sirolimus 6 Lomustine 6

Date Range

30 days 90 days 1 year All

Options

Has results Has announcements

NCT03973918 2024-10-31

BRAF

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Phase 2 Terminated

5 enrolled 15 charts

Astrocytoma, Glioblastoma, Glioma, Gliosarcoma

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