Clinical Trials

BreastCNSDermatologicGastrointestinalGenitourinaryThoracic

41 enrolled 32 charts

BreastCNS

Brain Neoplasms, Breast Neoplasms, Neoplasm Metastasis, Meningeal Carcinomatosis

NCT04588246 2025-06-06

Comparing Whole Brain Radiotherapy Using a Technique That Avoids the Hippocampus to Stereotactic Radiosurgery in Patients With Cancer That Has Spread to the Brain and Come Back in Other Areas of the Brain After Earlier Stereotactic Radiosurgery

Phase 3 Terminated

19 enrolled 19 charts

Brain Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Gastrointestinal Neoplasms, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Small Cell Lung Carcinoma

NCT03898908 2025-05-21

EBRAIN-MEL

48 enrolled 24 charts

CNSDermatologic

Brain Neoplasms, Melanoma, Neoplasm Metastasis

NCT03087591 2024-10-10

APN401 in Treating Patients With Recurrent or Metastatic Pancreatic Cancer, Colorectal Cancer, or Other Solid Tumors That Cannot Be Removed by Surgery

Phase 1 Completed

11 enrolled 26 charts

CNSGastrointestinal

Brain Neoplasms, Neoplasm Metastasis, Pancreatic Neoplasms, Colorectal Neoplasms

NCT00445965 2024-04-04

Iodine I 131 Monoclonal Antibody 3F8 in Treating Patients With Central Nervous System Cancer or Leptomeningeal Cancer

CNSDermatologicGynecologicOther solid neoplasmSarcomaThoracic

78 enrolled 11 charts

Familial ependymoma, Uveal Melanoma, Astrocytoma, Brain Neoplasms, Chondrosarcoma, Ependymoma, Glioblastoma, Glioma, Lung Neoplasms, Medulloblastoma, Melanoma, Neoplasm Metastasis, Neuroblastoma, Oligodendroglioma, Ovarian Neoplasms, Retinoblastoma, Rhabdomyosarcoma, Sarcoma, Osteosarcoma, Central Nervous System Neoplasms, Neuroectodermal Tumors, Primitive, Peripheral, Neuroectodermal Tumors, Primitive, Neoplasms, Neuroepithelial, Glioma, Subependymal, Gliosarcoma, Rhabdoid Tumor, Optic Nerve Glioma, Small Cell Lung Carcinoma, Desmoplastic Small Round Cell Tumor

NCT00928226 2024-01-30

Study of Fractionated Stereotactic Radiosurgery to Treat Large Brain Metastases

Phase NA Completed

56 enrolled 19 charts

Phase EARLY_PHASE1 Terminated

Brain Neoplasms, Neoplasm Metastasis, Neurologic Manifestations

NCT02774291 2023-08-04

Anti-NY ESO-1 mTCR Peripheral Blood Lymphocytes

3 enrolled 6 charts

Brain Neoplasms, Neoplasm Metastasis

NCT00080938 2023-06-29

Temozolomide and Radiation Therapy in Treating Patients With Brain Metastasis Secondary to Non-Small Cell Lung Cancer

26 enrolled 8 charts

CNSThoracic

Adenocarcinoma of Lung, Brain Neoplasms, Adenocarcinoma, Bronchiolo-Alveolar, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasm Metastasis

NCT02115139 2022-11-08

GRAY-B

58 enrolled 15 charts

CNSDermatologic

Brain Neoplasms, Melanoma, Neoplasm Metastasis

NCT00377156 2022-09-16

Stereotactic Radiation Therapy With or Without Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases

BreastCNSGenitourinaryThoracic

213 enrolled 16 charts

Brain Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasm Metastasis, Prostatic Neoplasms, Breast Neoplasms, Male

NCT01372774 2022-09-16

Stereotactic Radiosurgery or Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases That Have Been Removed By Surgery

194 enrolled 11 charts

Brain Neoplasms, Neoplasm Metastasis, Radiation Injuries, Neurotoxicity Syndromes

NCT00369785 2021-10-20

Donepezil in Treating Patients Who Have Undergone Radiation Therapy for Brain Tumors

198 enrolled 10 charts

CNSSarcoma

Astrocytoma, Brain Neoplasms, Craniopharyngioma, Ependymoma, Fatigue, Glioblastoma, Glioma, Medulloblastoma, Meningioma, Neoplasm Metastasis, Oligodendroglioma, Pinealoma, Radiation Injuries, Choroid Plexus Neoplasms, Neuroectodermal Tumors, Primitive, Glioma, Subependymal, Gliosarcoma

NCT01967823 2021-03-24

T Cell Receptor Immunotherapy Targeting NY-ESO-1 for Patients With NY-ESO-1 Expressing Cancer

BreastCNSDermatologicGastrointestinalThoracic

11 enrolled 12 charts

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Liver Neoplasms, Melanoma, Meningioma, Neoplasm Metastasis

NCT00814463 2019-02-26

Stereotactic Radiosurgery After Surgery in Treating Patients With Brain Metastases

Phase 2 Terminated

1 enrolled 6 charts

Brain Neoplasms, Neoplasm Metastasis

NCT00617539 2018-04-20

Irinotecan and Temozolomide in Treating Patients With Breast Cancer Who Have Received Previous Treatment for Brain Metastases

30 enrolled 10 charts

BreastCNS

Brain Neoplasms, Breast Neoplasms, Neoplasm Metastasis, Breast Neoplasms, Male

NCT01227954 2017-09-27

Avoiding the Hippocampus During Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases

113 enrolled 12 charts

Brain Neoplasms, Neoplasm Metastasis

NCT00566852 2017-08-21

Memantine in Preventing Side Effects in Patients Undergoing Whole-Brain Radiation Therapy for Brain Metastases From Solid Tumors

554 enrolled 12 charts

Brain Neoplasms, Neoplasm Metastasis, Neurotoxicity Syndromes

NCT00280748 2017-06-23

NRR

Phase 2 Terminated

10 enrolled 14 charts

CNSThoracic

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasm Metastasis

NCT00983359 2017-06-06

Stereotactic Radiation Therapy in Treating Patients With Brain Metastases

Phase NA Completed

40 enrolled 11 charts

Brain Neoplasms, Neoplasm Metastasis

NCT02047747 2016-09-22

A Phase II Study of Dacomitinib in Progressive Brain Metastases

Phase 2 Terminated

4 enrolled 4 charts

Brain Neoplasms, Neoplasm Metastasis

NCT00026494 2016-01-18

Temozolomide and Vinorelbine in Treating Patients With Recurrent Brain Metastases

Phase 1/2 Completed

49 enrolled 9 charts

Brain Neoplasms, Neoplasm Metastasis

NCT00450866 2014-02-28

Epothilone B in Treating Patients With CNS Metastases From Breast Cancer