Zotiraciclib (TG02) Plus Dose-Dense or Metronomic Temozolomide Followed by Randomized Phase II Trial of Zotiraciclib (TG02) Plus Temozolomide Versus Temozolomide Alone in Adults With Recurrent Anaplastic Astrocytoma and Glioblastoma
Phase 1/2 Terminated
53 enrolled 22 charts
Nivolumab for Recurrent or Progressive IDH Mutant Gliomas
Phase 2 Completed
35 enrolled 9 charts
Lerapolturev in Recurrent Malignant Glioma
Phase 2 Completed
121 enrolled 15 charts
REGN2810 in Pediatric Patients With Relapsed, Refractory Solid, or Central Nervous System (CNS) Tumors and Safety and Efficacy of REGN2810 in Combination With Radiotherapy in Pediatric Patients With Newly Diagnosed or Recurrent Glioma
Phase 1/2 Terminated
57 enrolled 31 charts
TPI 287 in Patients With Refractory or Recurrent Neuroblastoma or Medulloblastoma
Phase 1 Completed
18 enrolled 12 charts
Safety, Tolerability, Efficacy and Pharmacokinetics of Copanlisib in Pediatric Patients
Phase 1/2 Terminated
31 enrolled 17 charts
Study of Lenvatinib in Combination With Everolimus in Recurrent and Refractory Pediatric Solid Tumors, Including Central Nervous System Tumors
Phase 1/2 Completed
64 enrolled 29 charts
Stereotactic Radiology Versus Chemotherapy for Recurrent/Progressive Glioblastoma After Second-Line Chemotherapy
Phase 3 Completed
35 enrolled 13 charts
Dasatinib, Ifosfamide, Carboplatin, and Etoposide in Treating Young Patients With Metastatic or Recurrent Malignant Solid Tumors
Phase 1/2 Terminated
7 enrolled 9 charts
PIVOT IO 020
Phase 1/2 Terminated
15 enrolled 14 charts
A Phase 1 / 2 Dose Escalation Study of Locally-Administered OncoGelâ„¢ in Subjects With Recurrent Glioma
Phase 1/2 Terminated
4 enrolled 5 charts
A Study of Ramucirumab (LY3009806) in Children With Refractory Solid Tumors
Phase 1 Completed
29 enrolled 12 charts
A Phase I Trial of Anti-GD2 T-cells (1RG-CART)
Phase 1 Completed
17 enrolled 17 charts
Phase 1/2 Study of USL311 +/- Lomustine in Advanced Solid Tumors or Relapsed/Recurrent Glioblastoma Multiforme (GBM)
Phase 1/2 Terminated
26 enrolled 20 charts
Temozolomide,Thiotepa and Carboplatin With Autologous Stem Cell Rescue Followed by 13-cis-retinoic Acid in Patients With Recurrent/Refractory Malignant Brain Tumors
Phase 2 Completed
46 enrolled 5 charts
Safety and Efficacy of PF-299804 (Dacomitinib), a Pan-HER Irreversible Inhibitor, in Patients With Recurrent Glioblastoma With EGFR Amplification or Presence of EGFRvIII Mutation. A Phase II CT.
Phase 2 Completed
49 enrolled 9 charts
Pembrolizumab +/- Bevacizumab for Recurrent GBM
Phase 2 Completed
80 enrolled 13 charts
Study of Fixed vs. Flexible Filgrastim to Accelerate Bone Marrow Recovery After Chemotherapy in Children With Cancer
Phase 3 Terminated
23 enrolled 9 charts
STALLONe
Phase 1 Completed
5 enrolled 11 charts
High-Dose 131I-MIBG Therapy Combined With Vincristine and Five Days of Irinotecan for Resistant/Relapsed Neuroblastoma
Phase 1 Completed
32 enrolled 8 charts
A Phase II Study of 131I- Metaiodobenzylguanidine (MIBG) for Treatment of Metastatic or Unresectable Pheochromocytoma and Related Tumors
Phase 2 Completed
50 enrolled 7 charts
Antineoplaston Therapy in Treating Patients With Low-Grade Astrocytoma
Phase 2 Terminated
7 enrolled 6 charts
Antithymocyte Globulin, Clofarabine, and Rituximab in Treating Patients After an Unsuccessful Stem Cell Transplant
Phase 2 Terminated
12 enrolled 12 charts
Etanercept in Treating Young Patients With Idiopathic Pneumonia Syndrome After Undergoing a Donor Stem Cell Transplant
Phase 2 Completed
39 enrolled 12 charts
A Phase II Study of Oral LDE225 in Patients With Hedge-Hog (Hh)-Pathway Activated Relapsed Medulloblastoma (MB)
Phase 2 Completed
22 enrolled 12 charts
Carboplatin and Temozolomide (Temodar) for Recurrent and Symptomatic Residual Brain Metastases
Phase 1/2 Completed
17 enrolled 7 charts
Ondansetron in Preventing Nausea and Vomiting in Patients Undergoing Stem Cell Transplant
Phase 2 Completed
49 enrolled 4 charts
GVHD
Phase NA Completed
20 enrolled 27 charts
AMG 102 and Avastin for Recurrent Malignant Glioma
Phase 2 Completed
36 enrolled 9 charts
Memantine for Recurrent Glioblastoma
Phase 2 Terminated
4 enrolled 3 charts
BIBF 1120 for Recurrent High-Grade Gliomas
Phase 2 Completed
37 enrolled 11 charts
Bevacizumab for Recurrent Malignant Glioma
Phase 2 Completed
88 enrolled 11 charts
Radiosurgery and Avastin for Recurrent Malignant Gliomas
Phase NA Completed
15 enrolled 23 charts