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1 trials

Recent Start date Enrollment

Recruiting × AZD 6244 × CNS × Clear all

Phase

Status

Active not recruiting 7 Not yet recruiting 6 Withdrawn 2 Completed 2 Terminated 1 Recruiting 1 Approved for marketing 1

Sponsor Class

Study Type

Interventional 1

Sponsor

Cancer Type

Tumor-Agnostic 1 Other hematologic neoplasm 1 Myeloid 1 CNS 1

Conditions

Neurofibromatosis 1 1 Neurofibroma, Plexiform 1

Interventions

Temozolomide 67 Magnetic Resonance Spectroscopy 61 Radiotherapy 41 Specimen Handling 39 Radiosurgery 31 Bevacizumab 23 Cyclophosphamide 22 pembrolizumab 20 Radiation 18 Blood Specimen Collection 14 fludarabine 12 Lomustine 12 Irinotecan 12 Pemetrexed 11 Nivolumab 11 Etoposide 10 Carboplatin 10 Biopsy 10 Vincristine 9 Surgical Procedures, Operative 9 trametinib 8 lutetium Lu 177 dotatate 8 Ipilimumab 8 Fluorodeoxyglucose F18 8 naxitamab 7 fluciclovine F-18 7 Proton Therapy 7 Everolimus 7 Drug Therapy 7 olaparib 6

Date Range

30 days 90 days 1 year All

Options

Has results Has announcements

NCT06188741 2026-03-12

NF114

University of Alabama at Birmingham

Phase 2 Recruiting

Neurofibromatosis 1, Neurofibroma, Plexiform

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