Clinical Trials Browser

NIH × Carboplatin × CNS × Clear all

NCT03871257 2026-03-18

A Study of the Drugs Selumetinib Versus Carboplatin/Vincristine in Patients With Neurofibromatosis and Low-Grade Glioma

Phase 3 Active not recruiting

Neurofibromatosis 1

NCT03786783 2025-10-09

Dinutuximab, Sargramostim, and Combination Chemotherapy in Treating Patients With Newly Diagnosed High-Risk Neuroblastoma

Phase 2 Active not recruiting

42 enrolled 12 charts

Ganglioneuroblastoma

NCT04631029 2025-10-03

Testing the Addition of an Anti-cancer Drug, Entinostat, to the Usual Chemotherapy and Immunotherapy Treatment (Atezolizumab, Carboplatin and Etoposide) for Previously Untreated Aggressive Lung Cancer That Has Spread

Phase 1 Completed

3 enrolled 12 charts

Brain Neoplasms

NCT01295944 2025-08-05

Carboplatin and Bevacizumab for Recurrent Ependymoma

Phase 2 Completed

35 enrolled 17 charts

Brain Neoplasms, Ependymoma, Neoplasms, Neurologic Manifestations, Spinal Cord Neoplasms

NCT00867178 2022-01-13

Vorinostat Combined With Isotretinoin and Chemotherapy in Treating Younger Patients With Embryonal Tumors of the Central Nervous System

Phase 1 Completed

Medulloblastoma, Pinealoma

NCT00995007 2016-03-29

A Randomized Phase II Trial of Vandetanib (ZD6474) in Combination With Carboplatin Versus Carboplatin Alone Followed by Vandetanib Alone in Adults With Recurrent High-Grade Gliomas

Phase 2 Completed

112 enrolled 12 charts

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Gliosarcoma, Disease Progression

NCT00492687 2014-01-10

Radiation Therapy, Temozolomide, Tamoxifen, and Carboplatin in Treating Patients With Malignant Gliomas

Phase 2 Unknown

Astrocytoma, Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00025324 2013-12-18

Chemotherapy, Surgery, Radiation Therapy and Bone Marrow or Peripheral Stem Cell Transplantation in Treating Patients With Primary CNS Germ Cell Tumors

Phase 2 Unknown

Central Nervous System Neoplasms

NCT00392886 2013-12-18

Combination Chemotherapy With or Without Etoposide Followed By an Autologous Stem Cell Transplant in Treating Young Patients With Previously Untreated Malignant Brain Tumors

Phase 3 Unknown

Astrocytoma, Oligodendroglioma, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Rhabdoid Tumor

NCT00003015 2013-12-04

Carboplatin Plus Vincristine in Treating Children and Adolescents With Low Grade Glioma

Phase 3 Unknown

Oligodendroglioma, Central Nervous System Neoplasms

NCT00003859 2013-12-04

Surgery Plus Radiation Therapy With or Without Chemotherapy in Treating Children With Primitive Neuroectodermal Tumors of the CNS

Phase 3 Completed

Central Nervous System Neoplasms

NCT00014105 2013-12-04

Combination Chemotherapy in Treating Patients With Recurrent Glioblastoma Multiforme

Phase 1/2 Unknown

Brain Neoplasms, Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00025597 2013-09-17

Combination Chemotherapy Followed by Surgery in Treating Infants With Newly Diagnosed Neuroblastoma.

Phase 2 Completed

Neuroblastoma

NCT00025610 2013-09-17

Combination Chemotherapy in Treating Infants With Newly Diagnosed Neuroblastoma

Phase 2 Completed

Neuroblastoma

NCT00025623 2013-09-17

Combination Chemotherapy Followed by Surgery in Treating Infants With Newly Diagnosed Neuroblastoma

Phase 2 Completed

Neuroblastoma

NCT00276718 2013-09-17

Etoposide, Carboplatin, and Bleomycin in Treating Young Patients Undergoing Surgery For Malignant Germ Cell Tumors

Phase NA Unknown

CNSGenitourinaryGynecologic

Ovarian Germ Cell Cancer, Ovarian Neoplasms, Teratoma, Testicular Neoplasms, Central Nervous System Neoplasms

NCT00276731 2013-09-17

Combination Chemotherapy Followed By Surgery With or Without Radiation Therapy in Treating Young Patients With Stage II or Stage III Neuroblastoma

Phase 3 Unknown

Neuroblastoma

NCT00287950 2013-09-17

Combination Chemotherapy, Surgery, and Radiation Therapy in Treating Infants With Neuroblastoma

Phase NA Unknown

Neuroblastoma

NCT00293358 2013-09-17

Combination Chemotherapy and Radiation Therapy in Treating Patients With Germ Cell Tumors in the Brain

Phase 3 Completed

Central Nervous System Neoplasms

NCT00019422 2013-08-16

Lobradimil and Carboplatin in Treating Children With Brain Tumors

Phase 2 Completed

Familial ependymoma, Astrocytoma, Medulloblastoma, Central Nervous System Neoplasms, Optic Nerve Glioma

NCT00410631 2013-08-07

Observation, Combination Chemotherapy, Radiation Therapy, and/or Autologous Stem Cell Transplant in Treating Young Patients With Neuroblastoma

Phase 3 Unknown

Neuroblastoma

NCT00025077 2013-08-02

Combination Chemotherapy, Surgery or Radiation Therapy, and Peripheral Stem Cell Transplant in Treating Patients With Recurrent Medulloblastoma or Primitive Neuroectodermal and Pineal Tumors

Phase 2 Completed

Medulloblastoma, Central Nervous System Neoplasms

NCT00365755 2013-08-02

Combination Chemotherapy in Treating Young Patients Who Are Undergoing Surgery and an Autologous Bone Marrow Transplant for Disseminated Neuroblastoma

Phase 3 Completed

Neuroblastoma

NCT00416676 2013-08-02

Combination Chemotherapy and Surgery With or Without Radiation Therapy in Treating Patients With Stage 2 or Stage 3 Neuroblastoma

Phase 3 Unknown

Neuroblastoma

NCT00417053 2013-08-02

Combination Chemotherapy in Treating Infants With Newly Diagnosed Neuroblastoma Who Are Undergoing Surgery With or Without Autologous Bone Marrow or Peripheral Stem Cell Transplant

Phase 3 Unknown

Neuroblastoma

NCT00005976 2013-06-03

Pyrazoloacridine Plus Carboplatin in Treating Patients With Recurrent Glioma

Phase 2 Completed

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms, Gliosarcoma

NCT00352313 2012-05-02

ATN-161 and Carboplatin in Treating Patients With Recurrent Malignant Glioma

Phase 1/2 Completed

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms, Gliosarcoma

NCT00303940 2012-03-15

Talabostat Combined With Temozolomide or Carboplatin in Treating Young Patients With Relapsed or Refractory Brain Tumors or Other Solid Tumors

Phase 1 Completed

CNSGastrointestinalGenitourinaryGynecologicSarcoma

Familial ependymoma, Ovarian Germ Cell Cancer, Astrocytoma, Kidney Neoplasms, Liver Neoplasms, Medulloblastoma, Wilms Tumor, Neuroblastoma, Oligodendroglioma, Ovarian Neoplasms, Sarcoma, Osteosarcoma, Teratoma, Testicular Neoplasms, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Neuroectodermal Tumors, Primitive, Peripheral, Rhabdoid Tumor, Optic Nerve Glioma

NCT00021047 2012-03-08

Epirubicin, Carboplatin, and Capecitabine in Treating Patients With Unresectable Locally Advanced, Metastatic, or Recurrent Solid Tumor

Phase 1/2 Completed

CNSGastrointestinalHead & Neck

Squamous Cell Carcinoma of Head and Neck, Bile Duct Neoplasms, Esophageal Neoplasms, Head and Neck Neoplasms, Carcinoma, Hepatocellular, Liver Neoplasms, Salivary Gland Neoplasms, Stomach Neoplasms, Esthesioneuroblastoma, Olfactory

NCT00001502 2008-03-04

A Pediatric Phase I Trial of RMP-7 and Carboplatin in Brain Tumors

Phase 1 Completed

Brain Neoplasms, Glioma, Medulloblastoma