NCT06528691 2026-02-17
Entrectinib as a Single Agent in Upfront Therapy for Children <3 Years of Age With NTRK1/2/3 or ROS1-FUSED CNS Tumors
St. Jude Children's Research Hospital
Phase 2 Recruiting
Clinical Trials
71 trialsNCT02875314 2026-02-12
HeadStart4: Newly Diagnosed Children (<10 y/o) With Medulloblastoma and Other CNS Embryonal Tumors
Nationwide Children's Hospital
Phase 4 Active not recruiting
NCT05535166 2026-02-12
Molecular and Clinical Risk-Directed Therapy for Infants and Young Children With Newly Diagnosed Medulloblastoma
St. Jude Children's Research Hospital
Phase 2 Recruiting
NCT06528496 2026-02-10
N10: A Study of Reduced Chemotherapy and Monoclonal Antibody (mAb)-Based Therapy in Children With Neuroblastoma
Memorial Sloan Kettering Cancer Center
Phase 2 Recruiting
NCT07365410 2026-01-26
Furmonertinib 160mg vs 80mg + Chemotherapy in EGFR-Mutated NSCLC With Brain Metastases: Efficacy and Safety Study
Tianjin Medical University Cancer Institute and Hospital
Phase 2 Not yet recruiting
NCT05746481 2026-01-22
Tiragolumab and Atezolizumab in Patients With Non-squamous Non-small Cell Lung Cancer (NSCLC) and Untreated Brain Metastases
University of Pittsburgh
Phase 2 Terminated
NCT04711824 2025-12-23
SOLARA
Hoosier Cancer Research Network
Phase 1/2 Recruiting
NCT02066220 2025-12-04
International Society of Paediatric Oncology (SIOP) PNET 5 Medulloblastoma
Universitätsklinikum Hamburg-Eppendorf
Phase 2/3 Active not recruiting
NCT04964960 2025-10-31
Pembro+Chemo in Brain Mets
University of Kentucky
Phase 2 Terminated
NCT02605421 2025-10-21
Myeloablative Consolidation Therapy and Tandem Autologous Stem Cell Rescue in Patients With High-Risk Neuroblastoma
Masonic Cancer Center, University of Minnesota
Phase 2 Recruiting
NCT06822543 2025-09-29
TROPICAL-1
Latin American Cooperative Oncology Group
Phase 2 Recruiting
NCT04528680 2025-07-31
SC9/ABX
Northwestern University
Phase 1/2 Active not recruiting
NCT04740190 2025-06-11
TAC-GReD
The University of Hong Kong
Phase 2 Completed
NCT01386710 2025-04-09
Repeated Super-selective Intraarterial Cerebral Infusion Of Bevacizumab Plus Carboplatin For Treatment Of Relapsed/Refractory GBM And Anaplastic Astrocytoma
Northwell Health
Phase 1/2 Suspended
NCT05012254 2025-04-09
NIVIPI-Brain
Fundación GECP
Phase 2 Active not recruiting
NCT05278715 2024-10-15
Modified CV Regimen in Optic Pathway Glioma
Beijing Sanbo Brain Hospital
Phase 2 Recruiting
NCT01837862 2024-07-05
A Phase I Study of Mebendazole for the Treatment of Pediatric Gliomas
Northwell Health
Phase 1/2 Completed
NCT03206021 2024-04-05
COZMOS
The Hospital for Sick Children
Phase 1 Completed
NCT04610684 2024-03-13
Chemotherapy and Atezolizumab for Patients With Extensive Stage Small Cell Lung Cancer (SCLC) With Untreated, Asymptomatic Brain Metastases
Hoosier Cancer Research Network
Phase 2 Terminated
NCT01505569 2024-02-26
Auto Transplant for High Risk or Relapsed Solid or CNS Tumors
Masonic Cancer Center, University of Minnesota
Phase NA Completed
NCT01526603 2024-02-26
High Dose Chemotherapy and Autologous Transplant for Neuroblastoma
Masonic Cancer Center, University of Minnesota
Phase NA Completed
NCT02073968 2024-01-25
PAINT
Albert Einstein College of Medicine
Phase 2 Completed
NCT05718466 2023-07-17
Stereotactic Radiology Versus Chemotherapy for Recurrent/Progressive Glioblastoma After Second-Line Chemotherapy
Henry Ford Health System
Phase 3 Completed
NCT00788125 2023-07-14
Dasatinib, Ifosfamide, Carboplatin, and Etoposide in Treating Young Patients With Metastatic or Recurrent Malignant Solid Tumors
City of Hope Medical Center
Phase 1/2 Terminated
NCT00074165 2023-07-06
Treating Patients With Recurrent PCNSL With Carboplatin/BBBD and Adding Rituxan To The Treatment Regimen
OHSU Knight Cancer Institute
Phase 2 Terminated
NCT04507217 2023-05-25
Tislelizumab Combined With Pemetrexed/ Carboplatin in Patients With Brain Metastases of Non-squamous NSCLC
Sun Yat-sen University
Phase 2 Completed
NCT00253435 2023-04-10
N2001-02: I-MIBG With Intensive Chemotherapy and Autologous Stem Cell Rescue for High-Risk Neuroblastoma
Children's Hospital Los Angeles
Phase 2 Completed
NCT04211090 2022-11-16
CAP-BRAIN
Sun Yat-sen University
Phase 2 Unknown
NCT00075387 2022-05-03
Combination Chemotherapy With or Without Sodium Thiosulfate in Preventing Low Platelet Count While Treating Patients With Malignant Brain Tumors
OHSU Knight Cancer Institute
Phase 2 Unknown
NCT00303849 2022-03-17
Carboplatin, Melphalan, Etoposide Phosphate, Mannitol, and Sodium Thiosulfate in Treating Patients With Previously Treated Brain Tumors
OHSU Knight Cancer Institute
Phase 1/2 Completed
NCT05207904 2022-01-26
Tislelizumab Plus Chemotherapy as First-Line Treatment for Advanced Squamous NSCLC With Brain Metastases
Sun Yat-sen University
Phase 2 Unknown
NCT01542736 2022-01-11
Concurrent Carboplatin and Reduced Dose Craniospinal Radiation for Medulloblastoma and Primitive Neuroectodermal Tumor (PNET)
University of Colorado, Denver
Phase 2 Completed
NCT00983398 2021-10-26
Melphalan, Carboplatin, Mannitol, and Sodium Thiosulfate in Treating Patients With Recurrent or Progressive CNS Embryonal or Germ Cell Tumors
OHSU Knight Cancer Institute
Phase 1/2 Unknown
NCT00528437 2021-07-08
Temozolomide,Thiotepa and Carboplatin With Autologous Stem Cell Rescue Followed by 13-cis-retinoic Acid in Patients With Recurrent/Refractory Malignant Brain Tumors
NYU Langone Health
Phase 2 Completed
NCT01704716 2020-10-23
High Risk Neuroblastoma Study 1.8 of SIOP-Europe (SIOPEN)
St. Anna Kinderkrebsforschung
Phase 3 Recruiting
NCT00007813 2020-02-17
Peripheral Stem Cell Transplantation Plus Chemotherapy in Treating Patients With Malignant Solid Tumors
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Phase 1 Completed
NCT01014767 2019-08-20
Intercontinental Multidisciplinary Registry and Treatment Optimization Study for Choroid Plexus Tumors
Tufts Medical Center
Phase 3 Terminated
NCT00539500 2019-07-26
Autologous Stem Cell Rescue With CD133+ Selected Cells in High-Risk Neuroblastoma
M.D. Anderson Cancer Center
Phase 2/3 Terminated
NCT02253212 2018-10-12
SONOCLOUD
Assistance Publique - Hôpitaux de Paris
Phase 1/2 Completed
NCT00793845 2018-09-18
Tandem High-dose Chemotherapy and Autologous Stem Cell Rescue in Patients With High-risk Neuroblastoma
Samsung Medical Center
Phase 2 Completed
NCT00749723 2018-07-20
HIT-REZ-2005
University Hospital, Bonn
Phase 2/3 Completed
NCT01857453 2018-07-05
RSMA2010
Central Hospital, Nancy, France
Phase 2 Unknown
NCT01644955 2018-07-02
Carboplatin in Treating Patients With Recurrent High-Grade Gliomas
Ohio State University Comprehensive Cancer Center
Phase 1 Completed
NCT00276640 2018-04-20
SIOP-LGG-2004
Societe Internationale d'Oncologie Pediatrique
Phase NA Completed
NCT02130869 2017-12-22
A Pilot Study of Immunotherapy Including Haploidentical NK Cell Infusion Following CD133+ Positively-Selected Autologous Hematopoietic Stem Cells in Children With High Risk Solid Tumors or Lymphomas
St. Jude Children's Research Hospital
Phase 1 Completed
NCT02279992 2017-09-11
LevitraCarbo
Cedars-Sinai Medical Center
Phase EARLY_PHASE1 Terminated
NCT00362817 2017-06-01
Carboplatin and Temozolomide (Temodar) for Recurrent and Symptomatic Residual Brain Metastases
Ohio State University Comprehensive Cancer Center
Phase 1/2 Completed
NCT00238173 2017-04-21
Acetylcysteine, Mannitol, Combination Chemotherapy, and Sodium Thiosulfate in Treating Children With Malignant Brain Tumors
OHSU Knight Cancer Institute
Phase 1 Terminated
NCT00397501 2017-04-21
BBBD Followed By Methotrexate and Carboplatin With or Without Trastuzumab in Treating Women With Breast Cancer That Has Spread to the Brain
OHSU Knight Cancer Institute
Phase 1/2 Withdrawn
NCT00002931 2017-02-23
Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Relapsed Germ Cell Cancer
City of Hope Medical Center
Phase 2 Completed