Combination Chemotherapy Followed By Peripheral Stem Cell Transplant in Treating Young Patients With Newly Diagnosed Supratentorial Primitive Neuroectodermal Tumors or High-Risk Medulloblastoma
Phase 3 Completed
91 enrolled 24 charts
Induction Therapy Including 131 I-MIBG and Chemotherapy in Treating Patients With Newly Diagnosed High-Risk Neuroblastoma Undergoing Stem Cell Transplant, Radiation Therapy, and Maintenance Therapy With Isotretinoin
Phase 1 Completed
99 enrolled 11 charts
NANT 2015-02: A Phase 1 Study of Lorlatinib (PF-06463922)
Phase 1 Completed
65 enrolled 38 charts
Humanized Anti-GD2 Antibody Hu3F8 and Allogeneic Natural Killer Cells for High-Risk Neuroblastoma
Phase 1 Completed
85 enrolled
DFMO
Phase 1 Completed
30 enrolled
Evaluation of LY2606368 Therapy in Combination With Cyclophosphamide or Gemcitabine for Children and Adolescents With Refractory or Recurrent Group 3/Group 4 or SHH Medulloblastoma Brain Tumors
Phase 1 Completed
21 enrolled
Opsoclonus Myoclonus Syndrome/Dancing Eye Syndrome (OMS/DES) in Children With and Without Neuroblastoma (NBpos and NBneg)Opsoclonus Myoclonus Syndrome/Dancing Eye Syndrome (OMS/DES) in Children With and Without Neuroblastoma (NBpos and NBneg)
Phase 3 Completed
102 enrolled
Comparison of Radiation Therapy Regimens in Combination With Chemotherapy in Treating Young Patients With Newly Diagnosed Standard-Risk Medulloblastoma
Phase 3 Completed
549 enrolled 32 charts
Study of Nifurtimox to Treat Refractory or Relapsed Neuroblastoma or Medulloblastoma
Phase 2 Completed
112 enrolled 10 charts
Busulfan, Melphalan, and Stem Cell Transplant After Chemotherapy in Treating Patients With Newly Diagnosed High-Risk Neuroblastoma
Phase 1 Completed
150 enrolled 9 charts
A Phase I Trial of T Cells Expressing an Anti-GD2 Chimeric Antigen Receptor in Children and Young Adults With GD2+ Solid Tumors
Phase 1 Completed
15 enrolled
METRO-NB2012
Phase 2 Completed
18 enrolled
Treatment of Patients With Newly Diagnosed Medulloblastoma, Supratentorial Primitive Neuroectodermal Tumor, or Atypical Teratoid Rhabdoid Tumor
Phase 3 Completed
416 enrolled 16 charts
ASCR
Phase 1 Completed
14 enrolled
Crizotinib and Combination Chemotherapy in Treating Younger Patients With Relapsed or Refractory Solid Tumors or Anaplastic Large Cell Lymphoma
Phase 1 Completed
46 enrolled 24 charts
Combination Chemotherapy Plus Radiation Therapy in Treating Adult Patients With Brain Cancer
Phase 2 Completed
33 enrolled
Cyclophosphamide and Prednisone With or Without Immunoglobulin in Treating Abnormal Muscle Movement in Children With Neuroblastoma
Phase 3 Completed
53 enrolled 14 charts
N2007-02:Bevacizumab,Cyclophosphamide,& Zoledronic Acid in Patients W/ Recurrent or Refractory High-Risk Neuroblastoma
Phase 1 Completed
29 enrolled
Combination Chemotherapy in Treating Younger Patients With Newly Diagnosed, Non-metastatic Desmoplastic Medulloblastoma
Phase 2 Completed
26 enrolled 14 charts
Comparing Two Different Myeloablation Therapies in Treating Young Patients Who Are Undergoing a Stem Cell Transplant for High-Risk Neuroblastoma
Phase 3 Completed
665 enrolled 26 charts
Vorinostat Combined With Isotretinoin and Chemotherapy in Treating Younger Patients With Embryonal Tumors of the Central Nervous System
Phase 1 Completed
33 enrolled
A Phase I Trial of Anti-GD2 T-cells (1RG-CART)
Phase 1 Completed
17 enrolled 17 charts
Combination Chemotherapy and Surgery With or Without Isotretinoin in Treating Young Patients With Neuroblastoma
Phase 3 Completed
464 enrolled 25 charts
T Cell Receptor Immunotherapy Targeting NY-ESO-1 for Patients With NY-ESO-1 Expressing Cancer
Phase 2 Completed
11 enrolled 12 charts
Study of the IDO Pathway Inhibitor, Indoximod, and Temozolomide for Pediatric Patients With Progressive Primary Malignant Brain Tumors
Phase 1 Completed
81 enrolled
AflacST1402
Phase 1 Completed
13 enrolled
PEPI
Phase 2 Completed
13 enrolled 7 charts
SPRING
Phase NA Completed
13 enrolled 13 charts
Peripheral Stem Cell Transplantation Plus Chemotherapy in Treating Patients With Malignant Solid Tumors
Phase 1 Completed
21 enrolled
Cyclophosphamide, Topotecan, and Bevacizumab (CTB) in Patients With Relapsed/Refractory Ewing's Sarcoma and Neuroblastoma
Phase 2 Completed
9 enrolled 9 charts
CAR T Cell Receptor Immunotherapy Targeting EGFRvIII for Patients With Malignant Gliomas Expressing EGFRvIII
Phase 1/2 Completed
18 enrolled 25 charts
Observation or Radiation Therapy and/or Chemotherapy and Second Surgery in Treating Children Who Have Undergone Surgery for Ependymoma
Phase 2 Completed
378 enrolled 16 charts
Tandem High-dose Chemotherapy and Autologous Stem Cell Rescue in Patients With High-risk Neuroblastoma
Phase 2 Completed
40 enrolled
Radiation Therapy Compared With Chemotherapy and Radiation Therapy in Treating Patients With Newly Diagnosed Primary Central Nervous System (CNS) Germ Cell Tumor
Phase 3 Completed
24 enrolled 9 charts
Thalidomide, Celecoxib, and Combination Chemotherapy in Treating Patients With Relapsed or Refractory Malignant Glioma
Phase 2 Completed
Surgery in Treating Children With Neuroblastoma
Phase 3 Completed
968 enrolled
NB2004-HR
Phase 3 Completed
360 enrolled
Aprepitant, Granisetron, & Dexamethasone in Preventing Nausea & Vomiting in Pts. Receiving Cyclophosphamide Before a Stem Cell Transplant
Phase NA Completed
40 enrolled 9 charts
Etoposide, Cyclophosphamide, Thalidomide, Celecoxib, and Fenofibrate in Relapsed or Progressive Cancer
Phase 2 Completed
101 enrolled 10 charts
Radiation Therapy Plus Combination Chemotherapy in Treating Children With Medulloblastoma
Phase 3 Completed
421 enrolled
Combination Chemotherapy in Treating Children With Neuroblastoma
Phase 3 Completed
573 enrolled
Radiation Therapy, Chemotherapy, and Peripheral Stem Cell Transplantation in Treating Patients With Primitive Neuroectodermal Tumors
Phase 2 Completed
25 enrolled
Etoposide Plus Radiation Therapy Followed by Combination Chemotherapy in Treating Children With Newly Diagnosed Advanced Medulloblastoma
Phase 2 Completed
53 enrolled
Combination Chemotherapy Followed by Bone Marrow and/or Peripheral Stem Cell Transplantation in Treating Patients With Recurrent Medulloblastoma or CNS Germ Cell Tumors
Phase 2 Completed
31 enrolled
Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Infants With Malignant Brain or Spinal Cord Tumors
Phase 1 Completed
94 enrolled
Induction Chemotherapy Using Cyclophosphamide and Topotecan in Treating Patients Who Are Undergoing Autologous Peripheral Stem Cell Transplantation for Newly Diagnosed or Progressive Neuroblastoma
Phase 1 Completed
31 enrolled
Seneca Valley Virus-001 and Cyclophosphamide in Treating Young Patients With Relapsed or Refractory Neuroblastoma, Rhabdomyosarcoma, or Rare Tumors With Neuroendocrine Features
Phase 1 Completed
22 enrolled
Radiation Therapy and Combination Chemotherapy in Treating Young Patients With Medulloblastoma, Supratentorial Primitive Neuroectodermal Tumor, or Ependymoma
Phase NA Completed
567 enrolled
Therapy Based on Stage of Disease and Risk Assessment in Treating Children With Neuroblastoma
Phase 3 Completed
500 enrolled
Combination Chemotherapy or Observation Following Surgery in Treating Infants With Neuroblastoma
Phase 2 Completed
44 enrolled