Clinical Trials Browser

NCT00880061 2018-07-05

An Open Label Dose Escalation Safety Study of Convection-Enhanced Delivery of IL13-PE38QQR in Patients With Progressive Pediatric Diffuse Infiltrating Brainstem Glioma and Supratentorial High-grade Glioma

Phase 1 Terminated

7 enrolled

CNS

Brain Neoplasms, Glioma

NCT00024570 2014-11-14

Interstitial Infusion of IL13-PE38QQR Cytotoxin in Recurrent Malignant Glioma

Phase 1/2 Completed

60 enrolled

CNS

Astrocytoma, Glioblastoma, Glioma, Recurrence

NCT00378235 2014-11-13

Phase I/II Trial of Intracerebral IL13-PE38QQR Infusions in Pediatric Patients With Recurrent Malignant Glioma

Phase 1/2 Withdrawn

CNS

Glioma, Recurrence

NCT00036972 2013-06-26

Immunotoxin Therapy Before and After Surgery in Treating Patients With Recurrent Malignant Glioma

Phase 1 Completed

CNSSarcoma

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Central Nervous System Neoplasms, Gliosarcoma

NCT00006268 2013-06-24

Immunotoxin Therapy in Treating Patients With Malignant Glioma

Phase 1/2 Completed

CNSSarcoma

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Central Nervous System Neoplasms, Gliosarcoma

NCT00089427 2011-07-04

IL13-PE38QQR Infusion After Tumor Resection, Followed by Radiation Therapy With or Without Temozolomide in Patients With Newly Diagnosed Malignant Glioma

Phase 1 Completed

24 enrolled

CNS

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma

NCT00024557 2011-06-06

Histologic Effect/Safety of Pre/Post-Operative IL13-PE38QQR in Recurrent Resectable Supratentorial Malignant Glioma Patients

Phase 1 Completed

40 enrolled

CNS

Astrocytoma, Glioblastoma, Glioma, Recurrence

NCT00041587 2011-06-06

Pre-operative IL13-PE38QQR in Patients With Recurrent or Progressive Malignant Glioma

Phase 1/2 Completed

80 enrolled

CNS

Astrocytoma, Glioblastoma, Glioma, Neoplasms

NCT00076986 2011-06-06

The PRECISE Trial: Study of IL13-PE38QQR Compared to GLIADEL Wafer in Patients With Recurrent Glioblastoma Multiforme

Phase 3 Completed

300 enrolled

CNS

Brain Neoplasms, Glioblastoma, Glioma

NCT00053040 2010-09-24

Immunotoxin Therapy in Treating Children With Recurrent Malignant Gliomas

Phase 1/2 Withdrawn

CNS

Central Nervous System Neoplasms