Clinical Trials Browser

Brain Neoplasms, Carcinoma, Renal Cell, Medulloblastoma, Neoplasms, Germ Cell and Embryonal, Retinoblastoma, Rhabdomyosarcoma, Sarcoma, Central Nervous System Neoplasms, Hepatoblastoma, Rhabdoid Tumor

NCT02530502 2023-11-18

Radiation Therapy With Temozolomide and Pembrolizumab in Treating Patients With Newly Diagnosed Glioblastoma

Phase 1 Terminated

4 enrolled

CNS

Glioblastoma

NCT03406273 2023-09-28

Standardized Protocol of Surgery and Radiation for Patients With Brain Metastases in Relapsed Neuroblastoma

Phase NA Withdrawn

CNS

Neuroblastoma

NCT05832099 2023-04-27

Cognition-preserving Brain Irradiation for Treating Patients With Intracranial Meningioma in the Era of Modern Radiotherapeutic Techniques Including Proton Beam Therapy - a Prospective Study Focusing on Radiological Outcomes and Neurocognitive Endpoints

Not yet recruiting

74 enrolled

CNS

Meningioma

NCT03696355 2023-01-18

Study of GDC-0084 in Pediatric Patients With Newly Diagnosed Diffuse Intrinsic Pontine Glioma or Diffuse Midline Gliomas

Phase 1 Completed

27 enrolled

CNS

Diffuse Intrinsic Pontine Glioma, Astrocytoma, Brain Neoplasms, Glioblastoma, Central Nervous System Neoplasms

NCT05609162 2022-12-15

TBMPPF

Unknown

2,000 enrolled

CNS

Brain Neoplasms

NCT04854044 2021-05-12

ONC201 and Radiation Therapy Before Surgery for the Treatment of Recurrent Glioblastoma

Phase 1 Withdrawn

CNSSarcoma

Glioblastoma, Gliosarcoma

NCT02805179 2021-04-15

A Study of High-Dose Chemoradiation Using Biologically-Based Target Volume Definition in Patients With Glioblastoma

Phase 2 Completed

26 enrolled 14 charts

CNS

Glioma

NCT04583020 2020-11-30

Neoadjuvant PD-1 in Newly Diagnosed Glioblastoma

Phase 2 Unknown

42 enrolled

CNS

Glioblastoma

NCT03903419 2020-10-14

PAraDiGM

Phase NA Unknown

16 enrolled

CNS

Glioblastoma

NCT03506139 2020-09-09

Biologically-based Target Volumes to Treat Newly Diagnosed Glioblastoma

Phase 2 Withdrawn

CNS

Glioblastoma

NCT02431572 2020-04-28

A Pilot Study to Evaluate PBR PET in Brain Tumor Patients Treated With Chemoradiation or Immunotherapy

Phase NA Completed

11 enrolled 8 charts

CNSDermatologic

Brain Neoplasms, Glioblastoma, Melanoma

NCT04105374 2020-03-24

Testing the Addition of an Anti-cancer Viral Gene Therapy, Toca 511/Toca FC, to the Usual Treatment (Temozolomide and Radiation Therapy) for Newly Diagnosed Glioblastoma

Phase 2/3 Withdrawn

CNS

Astrocytoma, Glioblastoma, Oligodendroglioma

NCT00553150 2020-02-13

Everolimus, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma

Phase 1/2 Completed

122 enrolled 11 charts

CNSSarcoma

Astrocytoma, Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

Clinical Trials

PNOC023

Temporally-Modulated Pulsed Radiation Therapy Versus Standard Radiation Therapy for the Treatment of Newly Diagnosed, IDH Wildtype, MGMT-Unmethylated Glioblastoma

Ruxolitinib With Radiation and Temozolomide for Grade III Gliomas and Glioblastoma

PH Weighted Chemical Exchange Saturation Transfer MRI-Based Surgical Resection to Improve Survival in Patients With Glioblastoma

Testing the Addition of the Chemotherapy Drug Lomustine (Gleostine) to the Usual Treatment (Temozolomide and Radiation Therapy) for Newly Diagnosed MGMT Methylated Glioblastoma

Molecular and Clinical Risk-Directed Therapy for Infants and Young Children With Newly Diagnosed Medulloblastoma

Short Course Radiotherapy for the Treatment of Patients With Glioblastoma, SAGA Study

Dose-Escalated Photon IMRT or Proton Beam Radiation Therapy Versus Standard-Dose Radiation Therapy and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma

Chemotherapy and Radiation Therapy for the Treatment of IDH Wildtype Gliomas or Non-histological (Molecular) Glioblastomas

Mycophenolate Mofetil in Combination With Standard of Care for the Treatment of Glioblastoma

Radiation Therapy in Treating Patients With Recurrent Brain Tumors Who Have Undergone Previous Radiation Therapy

WP1066 and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma

OPTIMUM

Preoperative Radiosurgery for the Treatment of High Grade Glioma, NeoGlioma Trial

Peposertib and Radiation Therapy, Followed by Temozolomide for the Treatment of Patients With Newly Diagnosed MGMT Unmethylated Glioblastoma or Gliosarcoma

Ibrutinib With Radiation and Temozolomide in Patients With Newly Diagnosed Glioblastoma

Atezolizumab in Combination With Temozolomide and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma

GBM AGILE

Fluorine F 18 Fluorodopa-Labeled PET Scan in Planning Surgery and Radiation Therapy in Treating Patients With Newly Diagnosed High- or Low-Grade Malignant Glioma

A Pilot Study Investigating Upfront Adaptive Immunotherapy Approach in Children, Adolescent and Young Adult (CAYA) Patients With Replication-Repair Deficient (RRD) High-Grade Gliomas (HGG)

NausiCAA

Nivolumab, BMS-986205, and Radiation Therapy With or Without Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma

Tinostamustine With or Without Radiation Therapy in Treating Patients With Newly Diagnosed MGMT-Unmethylated Glioblastoma

Temozolomide, Radiation Therapy, and Tumor Treating Fields Therapy in Treating Participants With Glioblastoma

Study of the Combination of Vorinostat and Radiation Therapy for the Treatment of Patients With Brain Metastases

Combination of Sorafenib and Radiation for Brain Metastases and Primary Brain Tumors

Disulfiram/Copper With Concurrent Radiation Therapy and Temozolomide in Patients With Newly Diagnosed Glioblastoma

Pembrolizumab and Standard Therapy in Treating Patients With Glioblastoma

Vorinostat and Temsirolimus With or Without Radiation Therapy in Treating Younger Patients With Newly Diagnosed or Progressive Diffuse Intrinsic Pontine Glioma

Trial of Heat Shock Protein Peptide Complex-96 (HSPPC-96) Vaccine

Partial Brain RT, Temozolomide, Chloroquine, and TTF Therapy for the Treatment of Newly Diagnosed Glioblastoma

Comparison of Proton and Photon Radiotherapy of Brain Tumors (ProtoChoice-Hirn)

Hyperpolarized Imaging in Diagnosing Participants With Glioma

Repeated Superselective Intraarterial Cerebral Infusion (SIACI) of Bevacizumab With Temozolomide and Radiation Compared to Temozolomide and Radiation Alone in Newly Diagnosed GBM

Bavituximab With Radiation and Temozolomide for Patients With Newly Diagnosed Glioblastoma

Trotabresib in Combination With Vinorelbine and Radiation Therapy for the Treatment of HER2+ Breast Cancer With Central Nervous System or Leptomeningeal Metastasis

Auto Transplant for High Risk or Relapsed Solid or CNS Tumors

Radiation Therapy With Temozolomide and Pembrolizumab in Treating Patients With Newly Diagnosed Glioblastoma

Standardized Protocol of Surgery and Radiation for Patients With Brain Metastases in Relapsed Neuroblastoma

Cognition-preserving Brain Irradiation for Treating Patients With Intracranial Meningioma in the Era of Modern Radiotherapeutic Techniques Including Proton Beam Therapy - a Prospective Study Focusing on Radiological Outcomes and Neurocognitive Endpoints

Study of GDC-0084 in Pediatric Patients With Newly Diagnosed Diffuse Intrinsic Pontine Glioma or Diffuse Midline Gliomas

TBMPPF

ONC201 and Radiation Therapy Before Surgery for the Treatment of Recurrent Glioblastoma

A Study of High-Dose Chemoradiation Using Biologically-Based Target Volume Definition in Patients With Glioblastoma

Neoadjuvant PD-1 in Newly Diagnosed Glioblastoma

PAraDiGM

Biologically-based Target Volumes to Treat Newly Diagnosed Glioblastoma

A Pilot Study to Evaluate PBR PET in Brain Tumor Patients Treated With Chemoradiation or Immunotherapy

Testing the Addition of an Anti-cancer Viral Gene Therapy, Toca 511/Toca FC, to the Usual Treatment (Temozolomide and Radiation Therapy) for Newly Diagnosed Glioblastoma

Everolimus, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma