NCT06325683 2026-03-18
Anti-Lag-3 (Relatlimab) and Anti-PD-1 Blockade (Nivolumab) Versus Standard of Care (Lomustine) for the Treatment of Patients With Recurrent Glioblastoma
National Cancer Institute (NCI)
Phase 2 Recruiting
Clinical Trials
58 trialsNCT07053033 2026-03-09
Laser Interstitial Thermal Therapy (LITT) or Surgery and Adjuvant Reirradiation for Recurrent Brain Metastases (LaSAR BeaM)
M.D. Anderson Cancer Center
Phase 2 Recruiting
NCT06448286 2026-02-19
PH Weighted Chemical Exchange Saturation Transfer MRI-Based Surgical Resection to Improve Survival in Patients With Glioblastoma
Jonsson Comprehensive Cancer Center
Phase 3 Not yet recruiting
NCT07384884 2026-02-19
SLITT-GBM
King's College Hospital NHS Trust
Phase NA Not yet recruiting
NCT06528691 2026-02-17
Entrectinib as a Single Agent in Upfront Therapy for Children <3 Years of Age With NTRK1/2/3 or ROS1-FUSED CNS Tumors
St. Jude Children's Research Hospital
Phase 2 Recruiting
NCT07301268 2026-02-03
GI-102 Alone or With Pembrolizumab Before Surgery for Treatment of Recurrent or Progressive IDH Wildtype Glioblastoma and IDH Mutated Grade 4 Astrocytoma
Mayo Clinic
Phase 2 Suspended
NCT07089641 2025-11-24
ERAS801-SARG
Jonsson Comprehensive Cancer Center
Phase 1 Recruiting
NCT02792582 2025-11-12
A Phase II Trial of Intensity-Modulated Proton Therapy for Incompletely Resected Craniopharyngioma and Observation for Craniopharyngioma After Radical Resection
St. Jude Children's Research Hospital
Phase 2 Active not recruiting
NCT06831526 2025-11-12
Neoadjuvant Chemoradiotherapy With or Without Concurrent Azeliragon in Patients With Newly Diagnosed Glioblastoma
Washington University School of Medicine
Phase EARLY_PHASE1 Recruiting
NCT06964737 2025-10-29
Anti-GARP Chimeric Antigen Receptor T Cell Therapy for the Treatment of Recurrent Grade III or IV Gliomas
Ohio State University Comprehensive Cancer Center
Phase 1 Recruiting
NCT07197632 2025-09-29
MET-MRI
Technical University of Munich
Phase NA Recruiting
NCT02981940 2025-09-02
A Study of Abemaciclib in Recurrent Glioblastoma
Dana-Farber Cancer Institute
Phase 2 Active not recruiting
NCT03018288 2025-08-08
Radiation Therapy Plus Temozolomide and Pembrolizumab With and Without HSPPC-96 in Newly Diagnosed Glioblastoma (GBM)
National Institutes of Health Clinical Center (CC)
Phase 2 Terminated
NCT02507583 2025-05-07
Antisense102: Pilot Immunotherapy for Newly Diagnosed Malignant Glioma
Thomas Jefferson University
Phase 1 Completed
NCT02715609 2025-04-10
Disulfiram/Copper With Concurrent Radiation Therapy and Temozolomide in Patients With Newly Diagnosed Glioblastoma
Washington University School of Medicine
Phase 1/2 Completed
NCT06328036 2024-12-30
Testing the Combination of Anti-cancer Drugs Tiragolumab and Atezolizumab to Improve Outcomes for Patients With Recurrent Glioblastoma
National Cancer Institute (NCI)
Phase 2 Withdrawn
NCT03267836 2023-06-15
Neoadjuvant Avelumab and Hypofractionated Proton Radiation Therapy Followed by Surgery for Recurrent Radiation-refractory Meningioma
Washington University School of Medicine
Phase 1 Terminated
NCT03179449 2023-04-14
In Vivo Characterization of Macrophages in Pediatric Patients With Malignant Brain Tumors Using Ferumoxytol-enhanced MRI
Stanford University
Phase EARLY_PHASE1 Withdrawn
NCT00470496 2022-07-25
Photodynamic Therapy Using HPPH in Treating Patients Undergoing Surgery for Primary or Recurrent Head and Neck Cancer
Roswell Park Cancer Institute
Phase 1 Completed
NCT02794883 2022-04-18
Tremelimumab and Durvalumab in Combination or Alone in Treating Patients With Recurrent Malignant Glioma
Northwestern University
Phase 2 Completed
NCT00499616 2021-07-06
Combination Chemotherapy and Surgery With or Without Isotretinoin in Treating Young Patients With Neuroblastoma
Children's Oncology Group
Phase 3 Completed
NCT01567202 2020-09-09
Study of DC Vaccination Against Glioblastoma
Huashan Hospital
Phase 2 Unknown
NCT00047073 2020-08-03
Sirolimus in Treating Patients With Glioblastoma Multiforme
Jonsson Comprehensive Cancer Center
Phase 1/2 Completed
NCT04358666 2020-04-24
OPTMETACER
University Hospital, Caen
Phase NA Unknown
NCT02496520 2020-02-21
DEND/TIA
Clinica Universidad de Navarra, Universidad de Navarra
Phase 1/2 Completed
NCT03480867 2019-08-14
PARADIGMA
McGill University Health Centre/Research Institute of the McGill University Health Centre
Phase 1 Withdrawn
NCT01872221 2018-08-27
STEMRI
Institut Claudius Regaud
Phase NA Completed
NCT01644955 2018-07-02
Carboplatin in Treating Patients With Recurrent High-Grade Gliomas
Ohio State University Comprehensive Cancer Center
Phase 1 Completed
NCT00837928 2018-05-17
Bendamustine and Radiation Therapy in Treating Patients With Brain Metastases Caused by Solid Tumors
Ohio State University Comprehensive Cancer Center
Phase 1 Completed
NCT01339039 2017-11-17
Plerixafor (AMD3100) and Bevacizumab for Recurrent High-Grade Glioma
Dana-Farber Cancer Institute
Phase 1 Terminated
NCT02863484 2016-08-11
OCS
Kasr El Aini Hospital
Phase 4 Unknown
NCT00030628 2016-07-07
Radiosurgery With or Without Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases
Alliance for Clinical Trials in Oncology
Phase 3 Completed
NCT01213407 2016-05-19
GBM-Vax
Activartis Biotech
Phase 2 Completed
NCT00003484 2015-04-23
Radiolabeled Monoclonal Antibody Therapy After Radiation Therapy in Treating Patients With Primary Brain Tumors
Duke University
Phase 1 Completed
NCT00024570 2014-11-14
Interstitial Infusion of IL13-PE38QQR Cytotoxin in Recurrent Malignant Glioma
INSYS Therapeutics Inc
Phase 1/2 Completed
NCT00003461 2014-08-21
Radiolabeled Monoclonal Antibody Therapy in Treating Patients With Primary or Metastatic Brain Tumors
Duke University
Phase 1/2 Completed
NCT00238303 2014-05-23
Vorinostat in Treating Patients With Progressive or Recurrent Glioblastoma Multiforme
National Cancer Institute (NCI)
Phase 2 Completed
NCT01169129 2014-02-04
Surgery and Whole Brain Radiotherapy (RT) Versus Whole Brain Radiotherapy (RT) and Radiosurgery for 1-3 Resectable Brain Metastases
Barretos Cancer Hospital
Phase 3 Withdrawn
NCT00003842 2013-12-18
IL-4(38-37)-PE38KDEL Immunotoxin in Treating Patients With Recurrent Malignant Astrocytoma
National Cancer Institute (NCI)
Phase 1 Unknown
NCT00003859 2013-12-04
Surgery Plus Radiation Therapy With or Without Chemotherapy in Treating Children With Primitive Neuroectodermal Tumors of the CNS
National Cancer Institute (NCI)
Phase 3 Completed
NCT00002708 2013-11-19
Radiation Therapy With or Without Radiosurgery in Treating Patients With Brain Metastases
Radiation Therapy Oncology Group
Phase 3 Completed
NCT00003788 2013-11-06
Surgery, Radiation Therapy, and Chemotherapy With or Without Photodynamic Therapy in Treating Patients With Newly Diagnosed or Recurrent Malignant Supratentorial Gliomas
National Cancer Institute (NCI)
Phase 3 Unknown
NCT00003122 2013-08-26
Surgery in Treating Patients With Neuroblastoma
National Cancer Institute (NCI)
Phase 2 Unknown
NCT00003410 2013-06-26
Motexafin Gadolinium With MRI-Guided Surgery in Treating Patients With High-Grade Gliomas
National Cancer Institute (NCI)
Phase 1 Completed
NCT00003876 2013-06-26
Internal Radiation Therapy Plus Carmustine Implants in Treating Patients With Recurrent or Refractory Malignant Glioma
National Cancer Institute (NCI)
Phase 1 Completed
NCT00003574 2013-06-21
Radiation Therapy in Treating Patients With Progressive or Recurrent Malignant Brain Tumors
National Cancer Institute (NCI)
Phase 2 Completed
NCT00003467 2013-06-20
Carmustine in Treating Adults With Recurrent Supratentorial Low-Grade Glioma
Duke University
Phase 2 Completed
NCT00004262 2013-06-04
Radiation Therapy and Gadolinium Texaphyrin in Treating Patients With Supratentorial Glioblastoma Multiforme
National Cancer Institute (NCI)
Phase 1 Completed
NCT00004024 2013-04-05
Biological Therapy Following Surgery and Radiation Therapy in Treating Patients With Primary or Recurrent Astrocytoma or Oligodendroglioma
Barbara Ann Karmanos Cancer Institute
Phase 2 Completed
NCT00430079 2013-01-16
Use of EF5 to Measure the Oxygen Level in Tumor Cells of Patients Undergoing Surgery or Biopsy for Newly Diagnosed Supratentorial Malignant Glioma
National Cancer Institute (NCI)
Phase NA Terminated