Clinical Trials

Phase 2 Active not recruiting

Neuroblastoma

NCT04743661 2026-02-05

131I-Omburtamab, in Recurrent Medulloblastoma and Ependymoma

62 enrolled

Ependymoma, Medulloblastoma

NCT03224104 2025-11-26

STEAM

71 enrolled 18 charts

Phase 3 Active not recruiting

Astrocytoma, Glioblastoma

NCT00978458 2025-09-08

Radiation Therapy With or Without Temozolomide in Treating Patients With Low-Grade Glioma

540 enrolled

Astrocytoma, Brain Neoplasms, Glioma, Oligodendroglioma, Central Nervous System Neoplasms, Neurotoxicity Syndromes

NCT03345095 2025-07-01

MIRAGE

749 enrolled 15 charts

Glioblastoma

NCT02975882 2025-01-14

Nanoparticle Albumin-Bound Rapamycin, Temozolomide, and Irinotecan Hydrochloride in Treating Pediatric Patients With Recurrent or Refractory Solid Tumors

33 enrolled 15 charts

Central Nervous System Neoplasms

NCT00114140 2024-07-08

Temozolomide and Radiation Therapy in Treating Patients With Gliomas

136 enrolled 9 charts

Phase 3 Active not recruiting

Astrocytoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms

NCT00626990 2023-09-11

CATNON

751 enrolled 18 charts

Astrocytoma, Oligodendroglioma, Central Nervous System Neoplasms

NCT00482677 2023-08-22

Radiation Therapy With or Without Temozolomide in Treating Older Patients With Newly Diagnosed Glioblastoma Multiforme

562 enrolled 11 charts

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00387400 2023-08-04

Temozolomide + Everolimus in Newly Diagnosed, Recurrent, or Progressive Malignant Glioblastoma Multiforme

32 enrolled

Brain Neoplasms, Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00080938 2023-06-29

Temozolomide and Radiation Therapy in Treating Patients With Brain Metastasis Secondary to Non-Small Cell Lung Cancer

26 enrolled 8 charts

CNSThoracic

Adenocarcinoma of Lung, Brain Neoplasms, Adenocarcinoma, Bronchiolo-Alveolar, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasm Metastasis

NCT04091503 2023-04-25

Evaluate the Safety and Effectiveness of Intranasal Administration of Temozolomide in Patients With Glioblastoma

30 enrolled

Glioma, Gliosarcoma

NCT00100802 2023-02-15

Radiation Therapy, Temozolomide, and Lomustine in Treating Young Patients With Newly Diagnosed Gliomas

118 enrolled 8 charts

Astrocytoma, Glioblastoma, Spinal Cord Neoplasms, Central Nervous System Neoplasms, Gliosarcoma

NCT00004259 2019-09-12

Radiation Therapy Combined With Chemotherapy in Treating Patients With Anaplastic Astrocytoma or Mixed Gliomas

230 enrolled 14 charts

Astrocytoma, Glioma, Central Nervous System Neoplasms

NCT01164189 2019-02-28

TAVAREC

155 enrolled

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms, Gliosarcoma

NCT01019434 2018-07-09

Radiation Therapy and Temsirolimus or Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma

111 enrolled

Glioblastoma, Central Nervous System Neoplasms

NCT00077207 2018-05-16

Carboplatin, Vincristine, and Temozolomide in Treating Children With Progressive and/or Symptomatic Low-Grade Glioma

Phase NA Completed

66 enrolled 13 charts

Brain Neoplasms, Oligodendroglioma, Spinal Cord Neoplasms, Central Nervous System Neoplasms

NCT00068250 2018-02-07

Combination Chemotherapy, Monoclonal Antibody, and Radiation Therapy in Treating Patients With Primary Central Nervous System Lymphoma

Phase 1/2 Completed

60 enrolled 10 charts

CNSLymphoid

Lymphoma, Central Nervous System Neoplasms

NCT00086879 2017-07-27

Erlotinib Compared With Temozolomide or Carmustine in Treating Patients With Recurrent Glioblastoma Multiforme

110 enrolled

Brain Neoplasms, Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT01026493 2017-07-02

Veliparib and Temozolomide in Treating Patients With Recurrent Glioblastoma

Phase 1/2 Completed

257 enrolled 16 charts

Astrocytoma, Brain Neoplasms, Ependymoma, Glioblastoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms, Gliosarcoma

NCT00182819 2016-10-12

Radiation Therapy or Temozolomide in Treating Patients With Gliomas

709 enrolled

Astrocytoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms

NCT00516607 2015-02-10

Enzastaurin and Temozolomide in Treating Patients With Primary Gliomas

Phase 1 Unknown

28 enrolled

Astrocytoma, Brain Neoplasms, Ependymoma, Glioblastoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms, Gliosarcoma

NCT00311584 2014-09-30

Irinotecan and Temozolomide in Treating Young Patients With Recurrent Neuroblastoma

59 enrolled 10 charts

Neuroblastoma

NCT00006024 2014-02-13

Temozolomide Plus Lomustine Followed by Radiation Therapy in Treating Patients With High-Grade Malignant Glioma

32 enrolled

Astrocytoma, Brain Neoplasms, Central Nervous System Neoplasms

NCT00099125 2014-01-24

Radiation Therapy, Temozolomide, and Irinotecan in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

170 enrolled

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00003731 2012-09-24

Temozolomide in Treating Patients With Recurrent Oligodendroglial Tumors

39 enrolled

Glioma, Oligodendroglioma, Central Nervous System Neoplasms

NCT00006353 2012-09-24

Radiation Therapy With or Without Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

575 enrolled

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00020839 2012-09-24

Temozolomide With or Without Radiation Therapy to the Brain in Treating Patients With Stage IV Melanoma That Is Metastatic to the Brain

Phase 3 Terminated

23 enrolled

CNSDermatologic

Brain Neoplasms, Melanoma, Neoplasm Metastasis

NCT00128700 2012-09-24

Temozolomide and Radiation Therapy With or Without Vatalanib in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

Phase 1/2 Completed

20 enrolled

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00003304 2012-03-06

Temozolomide in Treating Patients With Recurrent Oligodendroglial Tumors

29 enrolled

Oligodendroglioma, Central Nervous System Neoplasms

NCT00717210 2008-07-17

NOA-04

318 enrolled