Clinical Trials Browser

Phase 1 × Valproic Acid × CNS × Clear all

NCT01552434 2025-10-14

Bevacizumab and Temsirolimus Alone or in Combination With Valproic Acid or Cetuximab in Treating Patients With Advanced or Metastatic Malignancy or Other Benign Disease

Phase 1 Active not recruiting

BreastCNSGenitourinaryHead & NeckLymphoidMyeloidSarcoma

Breast Neoplasms, Carcinoma, Transitional Cell, Endocrine Gland Neoplasms, Castleman Disease, Mouth Neoplasms, Neoplasm Metastasis, Neoplasms, Pharyngeal Neoplasms, Recurrence, Sarcoma, Soft Tissue Neoplasms, Thyroid Neoplasms, Urologic Neoplasms, Neurofibromatosis 2, Lymphangioleiomyomatosis, Neoplasms, Mesothelial, Erdheim-Chester Disease

NCT02648633 2017-05-31

Stereotactic Radiosurgery With Nivolumab and Valproate in Patients With Recurrent Glioblastoma

Phase 1 Terminated

Brain Neoplasms, Glioblastoma

NCT00437957 2017-02-23

Phase I Study of Temozolomide, Valproic Acid and Radiation Therapy in Patients With Brain Metastases

Phase 1 Terminated

Brain Neoplasms

NCT01204450 2016-12-23

Temsirolimus and Valproic Acid in Treating Young Patients With Relapsed Neuroblastoma, Bone Sarcoma, or Soft Tissue Sarcoma

Phase 1 Terminated

Neuroblastoma, Sarcoma, Osteosarcoma, Central Nervous System Neoplasms, Neuroectodermal Tumors, Primitive, Peripheral

NCT01861990 2015-05-22

Valproic Acid in Childhood Progressive Brain Tumors

Phase 1 Withdrawn

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Medulloblastoma, Neuroectodermal Tumors, Primitive

NCT00107458 2014-08-07

Valproic Acid in Treating Young Patients With Recurrent or Refractory Solid Tumors or CNS Tumors

Phase 1 Completed

Familial ependymoma, Astrocytoma, Medulloblastoma, Spinal Cord Neoplasms, Central Nervous System Neoplasms, Optic Nerve Glioma

NCT00513162 2012-09-19

Valproate and Etoposide for Patients With Neuronal Tumors and Brain Metastases

Phase 1 Completed

Brain Neoplasms, Neuroectodermal Tumors