Clinical Trials Browser

Completed × Vincristine × CNS × Clear all

NCT00336024 2026-01-23

Combination Chemotherapy Followed By Peripheral Stem Cell Transplant in Treating Young Patients With Newly Diagnosed Supratentorial Primitive Neuroectodermal Tumors or High-Risk Medulloblastoma

Phase 3 Completed

91 enrolled 24 charts

Medulloblastoma

NCT01175356 2026-01-23

Induction Therapy Including 131 I-MIBG and Chemotherapy in Treating Patients With Newly Diagnosed High-Risk Neuroblastoma Undergoing Stem Cell Transplant, Radiation Therapy, and Maintenance Therapy With Isotretinoin

Phase 1 Completed

99 enrolled 11 charts

Neuroblastoma, Ganglioneuroblastoma

NCT00085735 2025-01-14

Comparison of Radiation Therapy Regimens in Combination With Chemotherapy in Treating Young Patients With Newly Diagnosed Standard-Risk Medulloblastoma

Phase 3 Completed

549 enrolled 32 charts

Medulloblastoma

NCT01798004 2024-07-15

Busulfan, Melphalan, and Stem Cell Transplant After Chemotherapy in Treating Patients With Newly Diagnosed High-Risk Neuroblastoma

Phase 1 Completed

150 enrolled 9 charts

Neuroblastoma, Ganglioneuroblastoma

NCT00003375 2024-07-09

Observation or Radiation Therapy With or Without Combination Chemotherapy in Treating Patients With Low-Grade Glioma

Phase 2/3 Completed

Astrocytoma, Oligodendroglioma, Central Nervous System Neoplasms

NCT01837862 2024-07-05

A Phase I Study of Mebendazole for the Treatment of Pediatric Gliomas

Phase 1/2 Completed

Diffuse Intrinsic Pontine Glioma, Astrocytoma, Glioblastoma, Glioma, Gliosarcoma, Optic Nerve Glioma

NCT02085148 2024-04-22

A Phase I Dose Finding Study in Children With Solid Tumors Recurrent or Refractory to Standard Therapy

Phase 1 Completed

CNSGastrointestinalGenitourinarySarcoma

Neoplasms, Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Ewing, Hepatoblastoma

NCT00085202 2024-02-08

Treatment of Patients With Newly Diagnosed Medulloblastoma, Supratentorial Primitive Neuroectodermal Tumor, or Atypical Teratoid Rhabdoid Tumor

Phase 3 Completed

416 enrolled 16 charts

Central Nervous System Neoplasms, Rhabdoid Tumor

NCT01606878 2024-01-05

Crizotinib and Combination Chemotherapy in Treating Younger Patients With Relapsed or Refractory Solid Tumors or Anaplastic Large Cell Lymphoma

Phase 1 Completed

46 enrolled 24 charts

Neuroblastoma, Lymphoma, Large-Cell, Anaplastic

NCT02684058 2023-12-13

Study of Efficacy and Safety of Dabrafenib in Combination With Trametinib in Pediatric Patients With BRAF V600 Mutation Positive LGG or Relapsed or Refractory HGG Tumors

Phase 2 Completed

151 enrolled 45 charts 1 FDA

Astrocytoma, Ganglioneuroma, Glioblastoma, Glioma, Oligodendroglioma, Ganglioglioma, Neurocytoma

NCT00509353 2023-11-09

N2004-06: Irinotecan and Vincristine With 131I-MIBG Therapy for Resistant/Relapsed High-Risk Neuroblastoma

Phase 1 Completed

Neuroblastoma

NCT00846430 2023-08-30

Medical Treatment of "High-Risk" Neurofibromas

Phase 2 Completed

9 enrolled 9 charts

Neurofibroma, Neurofibromatosis 1

NCT00003309 2023-06-22

Combination Chemotherapy Plus Radiation Therapy in Treating Adult Patients With Brain Cancer

Phase 2 Completed

Ependymoma, Medulloblastoma, Central Nervous System Neoplasms

NCT01528046 2023-01-13

Metformin in Children With Relapsed or Refractory Solid Tumors

Phase 1 Completed

Brain Neoplasms, Neoplasms, Recurrence

NCT02017964 2023-01-09

Combination Chemotherapy in Treating Younger Patients With Newly Diagnosed, Non-metastatic Desmoplastic Medulloblastoma

Phase 2 Completed

26 enrolled 14 charts

CNSDermatologic

Basal Cell Nevus Syndrome, Medulloblastoma

NCT02035137 2022-06-08

N2011-01

Phase 2 Completed

114 enrolled 13 charts

Neuroblastoma

NCT00567567 2022-04-28

Comparing Two Different Myeloablation Therapies in Treating Young Patients Who Are Undergoing a Stem Cell Transplant for High-Risk Neuroblastoma

Phase 3 Completed

665 enrolled 26 charts

Neuroblastoma

NCT00867178 2022-01-13

Vorinostat Combined With Isotretinoin and Chemotherapy in Treating Younger Patients With Embryonal Tumors of the Central Nervous System

Phase 1 Completed

Medulloblastoma, Pinealoma

NCT01542736 2022-01-11

Concurrent Carboplatin and Reduced Dose Craniospinal Radiation for Medulloblastoma and Primitive Neuroectodermal Tumor (PNET)

Phase 2 Completed

8 enrolled 14 charts

Medulloblastoma

NCT00058370 2020-05-11

Intrathecal Radioimmunotherapy, Radiation Therapy, and Chemotherapy After Surgery in Treating Patients With Medulloblastoma

Phase NA Completed

6 enrolled 8 charts

Medulloblastoma, Central Nervous System Neoplasms

NCT01614132 2020-03-31

NOA-07

Phase 1/2 Completed

Medulloblastoma, Neoplasms, Neuroectodermal Tumors

NCT02786719 2020-03-12

SPRING

Phase NA Completed

13 enrolled 13 charts

Neuroblastoma

NCT01222780 2020-01-18

To Evaluate the Safety, Activity and Pharmacokinetics of Marqibo in Children and Adolescents With Refractory Cancer

Phase 1 Completed

CNSGenitourinaryLymphoidOther hematologic neoplasmSarcoma

Brain Neoplasms, Leukemia, Lymphoma, Neoplasms, Wilms Tumor, Neuroblastoma, Sarcoma, Hematologic Neoplasms

NCT00027846 2019-08-07

Observation or Radiation Therapy and/or Chemotherapy and Second Surgery in Treating Children Who Have Undergone Surgery for Ependymoma

Phase 2 Completed

378 enrolled 16 charts

Brain Neoplasms, Central Nervous System Neoplasms

NCT00002569 2018-06-18

Radiation Therapy With or Without Chemotherapy in Treating Patients With Anaplastic Oligodendroglioma

Phase 3 Completed

Glioma, Oligodendroglioma, Central Nervous System Neoplasms

NCT00077207 2018-05-16

Carboplatin, Vincristine, and Temozolomide in Treating Children With Progressive and/or Symptomatic Low-Grade Glioma

Phase NA Completed

66 enrolled 13 charts

Brain Neoplasms, Oligodendroglioma, Spinal Cord Neoplasms, Central Nervous System Neoplasms

NCT00276640 2018-04-20

SIOP-LGG-2004

Phase NA Completed

Astrocytoma, Oligodendroglioma, Spinal Cord Neoplasms, Central Nervous System Neoplasms, Optic Nerve Glioma

NCT00002806 2016-07-13

Chemotherapy Followed by Radiation Therapy in Treating Adults With Supratentorial Glioma

Phase 2 Completed

Astrocytoma, Central Nervous System Neoplasms

NCT00005796 2015-03-25

Combination Chemotherapy Plus Gene Therapy in Treating Patients With CNS Tumors

Phase 1 Completed

Familial ependymoma, Astrocytoma, Brain Neoplasms, Ependymoma, Glioblastoma, Glioma, Medulloblastoma, Oligodendroglioma, Central Nervous System Neoplasms, Gliosarcoma, Drug-Related Side Effects and Adverse Reactions

NCT00002875 2014-08-01

Radiation Therapy Plus Combination Chemotherapy in Treating Children With Medulloblastoma

Phase 3 Completed

Brain Neoplasms, Central Nervous System Neoplasms

NCT00003625 2014-07-28

Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Newly Diagnosed Brain Stem Glioma

Phase 1 Completed

Brain Neoplasms, Central Nervous System Neoplasms

NCT00003846 2014-07-28

Radiation Therapy, Chemotherapy, and Peripheral Stem Cell Transplantation in Treating Patients With Primitive Neuroectodermal Tumors

Phase 2 Completed

Neuroblastoma, Central Nervous System Neoplasms

NCT00003935 2014-07-28

Combination Chemotherapy Plus Radiation Therapy in Treating Children With Newly Diagnosed Brain Stem Glioma

Phase 1 Completed

Brain Neoplasms, Central Nervous System Neoplasms

NCT00003573 2014-07-25

Etoposide Plus Radiation Therapy Followed by Combination Chemotherapy in Treating Children With Newly Diagnosed Advanced Medulloblastoma

Phase 2 Completed

Brain Neoplasms, Central Nervous System Neoplasms

NCT00003141 2014-03-28

Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Infants With Malignant Brain or Spinal Cord Tumors

Phase 1 Completed

Astrocytoma, Brain Neoplasms, Neuroblastoma, Sarcoma, Spinal Cord Neoplasms, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Rhabdoid Tumor

NCT00070200 2014-02-13

Induction Chemotherapy Using Cyclophosphamide and Topotecan in Treating Patients Who Are Undergoing Autologous Peripheral Stem Cell Transplantation for Newly Diagnosed or Progressive Neuroblastoma

Phase 1 Completed

Neuroblastoma

NCT00303810 2014-01-28

Radiation Therapy and Combination Chemotherapy in Treating Young Patients With Medulloblastoma, Supratentorial Primitive Neuroectodermal Tumor, or Ependymoma

Phase NA Completed

Central Nervous System Neoplasms

NCT00002802 2013-12-19

Therapy Based on Stage of Disease and Risk Assessment in Treating Children With Neuroblastoma

Phase 3 Completed

Neuroblastoma

NCT00002803 2013-12-19

Combination Chemotherapy or Observation Following Surgery in Treating Infants With Neuroblastoma

Phase 2 Completed

Neuroblastoma

NCT00052455 2013-12-18

Temozolomide Compared to Procarbazine, Lomustine, and Vincristine in Treating Patients With Recurrent Malignant Glioma

Phase 3 Completed

Astrocytoma, Brain Neoplasms, Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00003859 2013-12-04

Surgery Plus Radiation Therapy With or Without Chemotherapy in Treating Children With Primitive Neuroectodermal Tumors of the CNS

Phase 3 Completed

Central Nervous System Neoplasms

NCT00025428 2013-12-04

Combination Chemotherapy Before Surgery in Treating Children With Localized Neuroblastoma

Phase 3 Completed

Neuroblastoma

NCT00025597 2013-09-17

Combination Chemotherapy Followed by Surgery in Treating Infants With Newly Diagnosed Neuroblastoma.

Phase 2 Completed

Neuroblastoma

NCT00025610 2013-09-17

Combination Chemotherapy in Treating Infants With Newly Diagnosed Neuroblastoma

Phase 2 Completed

Neuroblastoma

NCT00025623 2013-09-17

Combination Chemotherapy Followed by Surgery in Treating Infants With Newly Diagnosed Neuroblastoma

Phase 2 Completed

Neuroblastoma

NCT00002944 2013-09-09

Combination Chemotherapy in Treating Children With Progressive Brain Tumors

Phase 3 Completed

Astrocytoma, Brain Neoplasms, Central Nervous System Neoplasms, Optic Nerve Glioma

NCT00004224 2013-08-26

Combination Chemotherapy Followed by Radiation Therapy in Treating Children With Localized Ependymoma

Phase 2 Completed

Central Nervous System Neoplasms

NCT00006461 2013-08-09

Combination Chemotherapy Followed by Second-Look Surgery and Radiation Therapy in Treating Children With Nonmetastatic Medulloblastoma or Primitive Neuroectodermal Tumor

Phase 3 Completed

Untreated Childhood Medulloblastoma

NCT00365755 2013-08-02

Combination Chemotherapy in Treating Young Patients Who Are Undergoing Surgery and an Autologous Bone Marrow Transplant for Disseminated Neuroblastoma

Phase 3 Completed

Neuroblastoma

NCT00006258 2013-07-18

Combination Chemotherapy Followed by Radiation Therapy in Treating Patients With Medulloblastoma, Supratentorial Primitive Neuroectodermal Tumor, or Ependymoma

Phase 2 Completed

Ependymoma, Medulloblastoma, Central Nervous System Neoplasms, Neuroectodermal Tumors, Primitive