Bintrafusp Alfa and Pimasertib for the Treatment of Patients With Brain Metastases
Phase 1/2 Terminated
8 enrolled 13 charts
Zotiraciclib (TG02) Plus Dose-Dense or Metronomic Temozolomide Followed by Randomized Phase II Trial of Zotiraciclib (TG02) Plus Temozolomide Versus Temozolomide Alone in Adults With Recurrent Anaplastic Astrocytoma and Glioblastoma
Phase 1/2 Terminated
53 enrolled 22 charts
Spencer
Phase 1/2 Terminated
70 enrolled 20 charts
Testing the Safety and Tolerability of CX-4945 in Patients With Recurrent Medulloblastoma Who May or May Not Have Surgery
Phase 1/2 Terminated
21 enrolled
Open-Label Safety and Tolerability Study of INCB057643 in Subjects With Advanced Malignancies
Phase 1/2 Terminated
137 enrolled 31 charts
67Cu-SARTATE⢠Peptide Receptor Radionuclide Therapy Administered to Pediatric Patients With High-Risk, Relapsed, Refractory Neuroblastoma
Phase 1/2 Terminated
21 enrolled
A Study of Ad-RTS-hIL-12 + Veledimex in Pediatric Subjects With Brain Tumors Including DIPG
Phase 1/2 Terminated
6 enrolled 14 charts
Safety, Tolerability, PK/PD & Preliminary Efficacy of SKL27969 in Advanced Solid Tumors Patients
Phase 1/2 Terminated
15 enrolled
REGN2810 in Pediatric Patients With Relapsed, Refractory Solid, or Central Nervous System (CNS) Tumors and Safety and Efficacy of REGN2810 in Combination With Radiotherapy in Pediatric Patients With Newly Diagnosed or Recurrent Glioma
Phase 1/2 Terminated
57 enrolled 31 charts
Studying the Safety, Efficacy, and Pharmacokinetic Characteristics of BNCT in Patients With Recurrent High-grade Gliomas
Phase 1/2 Terminated
7 enrolled
[18F]Fluciclovine and [18F]FLT PET/CT Assessment of Primary High-Grade Brain Tumors
Phase 1/2 Terminated
10 enrolled 7 charts
Oral AMXT 1501 Dicaprate in Combination With IV DFMO
Phase 1/2 Terminated
15 enrolled
A Study Evaluating the Safety, Tolerability, Pharmacokinetics and Preliminary Activity of Idasanutlin in Combination With Either Chemotherapy or Venetoclax in Treatment of Pediatric and Young Adult Participants With Relapsed/Refractory Acute Leukemias or Solid Tumors
Phase 1/2 Terminated
38 enrolled 34 charts
A Study of Selinexor in Combination With Standard of Care Therapy for Newly Diagnosed or Recurrent Glioblastoma
Phase 1/2 Terminated
74 enrolled 23 charts
RO4929097 and Whole-Brain Radiation Therapy or Stereotactic Radiosurgery in Treating Patients With Brain Metastases From Breast Cancer
Phase 1/2 Terminated
5 enrolled 6 charts
Randomized Efficacy Study of TPI 287 to Treat Primary Refractory or Early Relapsed Neuroblastoma
Phase 1/2 Terminated
14 enrolled 11 charts
Berubicin in Adult Patients With Recurrent Glioblastoma Multiforme (WHO Grade IV)
Phase 1/2 Terminated
5 enrolled
CamBMT1
Phase 1/2 Terminated
26 enrolled
AsiDNA
Phase 1/2 Terminated
8 enrolled
Safety, Tolerability, Efficacy and Pharmacokinetics of Copanlisib in Pediatric Patients
Phase 1/2 Terminated
31 enrolled 17 charts
T-DM1 Alone Versus T-DM1 and Metronomic Temozolomide in Secondary Prevention of HER2-Positive Breast Cancer Brain Metastases Following Stereotactic Radiosurgery
Phase 1/2 Terminated
12 enrolled 16 charts
177Lu-DTPA-Omburtamab Radioimmunotherapy for Recurrent or Refractory Medulloblastoma
Phase 1/2 Terminated
2 enrolled 9 charts
Study of the Safety and Efficacy of Humanized 3F8 Bispecific Antibody (Hu3F8-BsAb) in Patients With Relapsed/Refractory Neuroblastoma, Osteosarcoma and Other Solid Tumor Cancers
Phase 1/2 Terminated
12 enrolled 15 charts
AXL1717
Phase 1/2 Terminated
10 enrolled 8 charts
PIVOT IO 020
Phase 1/2 Terminated
15 enrolled 14 charts
NTX-301 Monotherapy in Advanced Solid Tumours and in Combination With Platinum-based Chemotherapy in Advanced Ovarian & Bladder Cancer and in Combination With Temozolomide in High-grade Glioma
Phase 1/2 Terminated
12 enrolled
329
Phase 1/2 Terminated
12 enrolled 13 charts
Glyburide vs Placebo as Prophylaxis Against Cerebral Edema in Patients Receiving Radiosurgery for Brain Metastases (RAD 1502/UAB 1593)
Phase 1/2 Terminated
1 enrolled 6 charts
Intraarterial Infusion Of Erbitux and Bevacizumab For Relapsed/Refractory Intracranial Glioma In Patients Under 22
Phase 1/2 Terminated
13 enrolled 6 charts
A Phase 1 / 2 Dose Escalation Study of Locally-Administered OncoGel⢠in Subjects With Recurrent Glioma
Phase 1/2 Terminated
4 enrolled 5 charts
Study of the Combination of KD019 and Trastuzumab in Subjects With HER2-Positive Metastatic Breast Cancer
Phase 1/2 Terminated
17 enrolled 19 charts
Study of EZN-2208 Pediatric Patients With Solid Tumors
Phase 1/2 Terminated
32 enrolled
Phase I / II Vorinostat, Erlotinib and Temozolomide for Recurrent Glioblastoma Multiforme (GBM)
Phase 1/2 Terminated
21 enrolled 8 charts
Phase 1/2 Study of USL311 +/- Lomustine in Advanced Solid Tumors or Relapsed/Recurrent Glioblastoma Multiforme (GBM)
Phase 1/2 Terminated
26 enrolled 20 charts
Ketogenic Diet With Radiation and Chemotherapy for Newly Diagnosed Glioblastoma
Phase 1/2 Terminated
14 enrolled
IDEB-glioma
Phase 1/2 Terminated
5 enrolled
A Phase I/II Study of Ribociclib,a CDK4/6 Inhibitor, Following Radiation Therapy
Phase 1/2 Terminated
11 enrolled 10 charts
Cetuximab-IRDye 800CW in Detecting Tumors in Patients With Malignant Glioma Undergoing Surgery
Phase 1/2 Terminated
3 enrolled 7 charts
DOTA-TOC
Phase 1/2 Terminated
300 enrolled 5 charts
A Study to Demonstrate the Safety and Preliminary Efficacy of 18F-FLT in Patients With Solid Tumours or Lymphoma
Phase 1/2 Terminated
94 enrolled
Phase I/II Bevacizumab Versus Bevacizumab Plus TPI 287 for Recurrent Glioblastoma
Phase 1/2 Terminated
12 enrolled 7 charts
Study of Vismodegib in Combination With Temozolomide Versus Temozolomide Alone in Patients With Medulloblastomas With an Activation of the Sonic Hedgehog Pathway
Phase 1/2 Terminated
24 enrolled
Double Cord Blood Transplant for Patients With Malignant and Non-malignant Disorders
Phase 1/2 Terminated
1 enrolled 8 charts
A Study of Intraventricular Liposomal Encapsulated Ara-C (DepoCyt) in Patients With Recurrent Glioblastoma
Phase 1/2 Terminated
12 enrolled 12 charts
Safety and Efficacy of INC280 and Buparlisib (BKM120) in Patients With Recurrent Glioblastoma
Phase 1/2 Terminated
43 enrolled 22 charts
Intrathecal Rituximab in Lymphoid Malignancies Involving Central Nervous System
Phase 1/2 Terminated
4 enrolled 7 charts
Phase I/II: Decitabine/Vaccine Therapy in Relapsed/Refractory Pediatric High Grade Gliomas/Medulloblastomas/CNS PNETs
Phase 1/2 Terminated
1 enrolled 6 charts
Radiosurgery for Glioblastoma Multiforme
Phase 1/2 Terminated
4 enrolled 3 charts
Image Guided Reirradiation of High-grade Glioma
Phase 1/2 Terminated
31 enrolled
Phase 1b/2 Study of BKM120 Plus Trastuzumab in Patients With HER2-positive Breast Cancer
Phase 1/2 Terminated
72 enrolled 15 charts