Clinical Trials Browser

Phase 3 × NETWORK × CNS × Clear all

NCT03126916 2026-02-27

Testing the Addition of 131I-MIBG or Lorlatinib to Intensive Therapy in People With High-Risk Neuroblastoma (NBL)

Phase 3 Recruiting

Neuroblastoma, Ganglioneuroblastoma

NCT05382338 2026-02-24

A Study of Treatment for Medulloblastoma Using Sodium Thiosulfate to Reduce Hearing Loss

Phase 3 Recruiting

Medulloblastoma

NCT05904119 2026-02-17

LEGATO

Phase 3 Recruiting

Glioblastoma

NCT06809322 2026-02-17

VIGOR

Phase 3 Recruiting

Astrocytoma

NCT00336024 2026-01-23

Combination Chemotherapy Followed By Peripheral Stem Cell Transplant in Treating Young Patients With Newly Diagnosed Supratentorial Primitive Neuroectodermal Tumors or High-Risk Medulloblastoma

Phase 3 Completed

91 enrolled 24 charts

Medulloblastoma

NCT03550391 2026-01-13

Stereotactic Radiosurgery Compared With Hippocampal-Avoidant Whole Brain Radiotherapy (HA-WBRT) Plus Memantine for 5 or More Brain Metastases

Phase 3 Recruiting

Brain Neoplasms

NCT02176967 2025-12-22

Response and Biology-Based Risk Factor-Guided Therapy in Treating Younger Patients With Non-high Risk Neuroblastoma

Phase 3 Active not recruiting

Neuroblastoma, Ganglioneuroblastoma

NCT03418961 2025-10-08

S1501 Dual Observational and Randomized Cohort Study of Patients With Metastatic HER-2+ Breast Cancer at Risk of Cardiac Toxicity

Phase 3 Recruiting

Brain Neoplasms, Breast Neoplasms, Cardiotoxicity

NCT00978458 2025-09-08

Radiation Therapy With or Without Temozolomide in Treating Patients With Low-Grade Glioma

Phase 3 Active not recruiting

Astrocytoma, Brain Neoplasms, Glioma, Oligodendroglioma, Central Nervous System Neoplasms, Neurotoxicity Syndromes

NCT03345095 2025-07-01

MIRAGE

Phase 3 Completed

749 enrolled 15 charts

Glioblastoma

NCT00392327 2025-06-13

Chemotherapy and Radiation Therapy in Treating Young Patients With Newly Diagnosed, Previously Untreated, High-Risk Medulloblastoma/PNET

Phase 3 Active not recruiting

379 enrolled 29 charts

Medulloblastoma

NCT00085735 2025-01-14

Comparison of Radiation Therapy Regimens in Combination With Chemotherapy in Treating Young Patients With Newly Diagnosed Standard-Risk Medulloblastoma

Phase 3 Completed

549 enrolled 32 charts

Medulloblastoma

NCT00626990 2023-09-11

CATNON

Phase 3 Active not recruiting

751 enrolled 18 charts

Astrocytoma, Oligodendroglioma, Central Nervous System Neoplasms

NCT00482677 2023-08-22

Radiation Therapy With or Without Temozolomide in Treating Older Patients With Newly Diagnosed Glioblastoma Multiforme

Phase 3 Completed

562 enrolled 11 charts

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00033293 2023-04-18

Cyclophosphamide and Prednisone With or Without Immunoglobulin in Treating Abnormal Muscle Movement in Children With Neuroblastoma

Phase 3 Completed

53 enrolled 14 charts

Neuroblastoma

NCT00567567 2022-04-28

Comparing Two Different Myeloablation Therapies in Treating Young Patients Who Are Undergoing a Stem Cell Transplant for High-Risk Neuroblastoma

Phase 3 Completed

665 enrolled 26 charts

Neuroblastoma

NCT00499616 2021-07-06

Combination Chemotherapy and Surgery With or Without Isotretinoin in Treating Young Patients With Neuroblastoma

Phase 3 Completed

464 enrolled 25 charts

Neuroblastoma

NCT01290939 2021-02-15

Bevacizumab and Lomustine for Recurrent GBM

Phase 3 Completed

Brain Neoplasms, Cognition Disorders, Glioblastoma

NCT03015701 2019-12-23

S9005 Mifepristone in Meningioma

Phase 3 Completed

Meningioma

NCT03722355 2019-11-12

Hyperfractionated RT With BCNU Versus Conventional RT With BCNU for Supratentorial Malignant Glioma

Phase 3 Completed

Astrocytoma, Glioblastoma, Glioma

NCT00004259 2019-09-12

Radiation Therapy Combined With Chemotherapy in Treating Patients With Anaplastic Astrocytoma or Mixed Gliomas

Phase 3 Completed

230 enrolled 14 charts

Astrocytoma, Glioma, Central Nervous System Neoplasms

NCT00085098 2018-09-07

Radiation Therapy Compared With Chemotherapy and Radiation Therapy in Treating Patients With Newly Diagnosed Primary Central Nervous System (CNS) Germ Cell Tumor

Phase 3 Completed

24 enrolled 9 charts

Brain Neoplasms, Central Nervous System Neoplasms

NCT00002569 2018-06-18

Radiation Therapy With or Without Chemotherapy in Treating Patients With Anaplastic Oligodendroglioma

Phase 3 Completed

Glioma, Oligodendroglioma, Central Nervous System Neoplasms

NCT00566852 2017-08-21

Memantine in Preventing Side Effects in Patients Undergoing Whole-Brain Radiation Therapy for Brain Metastases From Solid Tumors

Phase 3 Completed

554 enrolled 12 charts

Brain Neoplasms, Neoplasm Metastasis, Neurotoxicity Syndromes

NCT00003119 2017-03-13

Surgery in Treating Children With Neuroblastoma

Phase 3 Completed

Neuroblastoma

NCT00182819 2016-10-12

Radiation Therapy or Temozolomide in Treating Patients With Gliomas

Phase 3 Completed

Astrocytoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms

NCT00078988 2015-05-07

High-Dose Chemotherapy Plus Autologous Stem Cell Transplantation Compared With Intermediate-Dose Chemotherapy Plus Autologous Stem Cell Transplantation With or Without Isotretinoin in Treating Young Patients With Recurrent High-Grade Gliomas

Phase 3 Completed

Astrocytoma, Brain Neoplasms, Central Nervous System Neoplasms

NCT00002875 2014-08-01

Radiation Therapy Plus Combination Chemotherapy in Treating Children With Medulloblastoma

Phase 3 Completed

Brain Neoplasms, Central Nervous System Neoplasms

NCT00003093 2014-08-01

Combination Chemotherapy in Treating Children With Neuroblastoma

Phase 3 Completed

Neuroblastoma

NCT00002708 2013-11-19

Radiation Therapy With or Without Radiosurgery in Treating Patients With Brain Metastases

Phase 3 Completed

Brain Neoplasms, Neoplasm Metastasis

NCT00002944 2013-09-09

Combination Chemotherapy in Treating Children With Progressive Brain Tumors

Phase 3 Completed

Astrocytoma, Brain Neoplasms, Central Nervous System Neoplasms, Optic Nerve Glioma

NCT00002545 2013-08-13

Radiation Therapy Plus Chemotherapy in Treating Patients With Supratentorial Glioblastoma Multiforme

Phase 3 Completed

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00006461 2013-08-09

Combination Chemotherapy Followed by Second-Look Surgery and Radiation Therapy in Treating Children With Nonmetastatic Medulloblastoma or Primitive Neuroectodermal Tumor

Phase 3 Completed

Untreated Childhood Medulloblastoma

NCT00004188 2013-05-17

Combination Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Neuroblastoma

Phase 3 Completed

Neuroblastoma

NCT00017147 2013-01-30

S0001 RT and Carmustine With or Without O6BG in Patients With New Glioblastoma Multiforme or Gliosarcoma

Phase 3 Completed

Glioblastoma, Gliosarcoma

NCT00003916 2012-09-24

Standard Radiation Therapy With or Without Stereotactic Radiation Therapy in Treating Patients With Glioma

Phase 3 Completed

Astrocytoma, Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00003938 2012-09-24

Liposomal Amphotericin B in Treating Granulocytopenia and Persistent Unexplained Fever in Cancer Patients

Phase 3 Completed

BreastCNSDermatologicGenitourinaryGynecologicLymphoidMyeloidOther hematologic neoplasmPlasma cellSarcoma

Teratoma, Testicular, Pdgfra-Associated Chronic Eosinophilic Leukemia, Immunoglobulin Light-chain Amyloidosis, Carcinoma, Ovarian Epithelial, Blast Crisis, Breast Neoplasms, Burkitt Lymphoma, Fever, Hodgkin Disease, Immunoblastic Lymphadenopathy, Infections, Leukemia, Hairy Cell, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Waldenstrom Macroglobulinemia, Monoclonal Gammopathy of Undetermined Significance, Multiple Myeloma, Mycosis Fungoides, Neoplasms, Wilms Tumor, Neuroblastoma, Neutropenia, Polycythemia Vera, Recurrence, Sezary Syndrome, Teratoma, Testicular Neoplasms, Thrombocythemia, Essential, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Biphenotypic, Acute, Leukemia, Prolymphocytic, Leukemia, Myeloid, Accelerated Phase, Leukemia, Myeloid, Chronic-Phase, Leukemia, Neutrophilic, Chronic, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, Large B-Cell, Diffuse, Lymphoma, T-Cell, Cutaneous, Lymphoma, Large-Cell, Anaplastic, Carcinoma, Embryonal, Seminoma, Endodermal Sinus Tumor, Lymphoma, B-Cell, Marginal Zone, Hot Flashes, Lymphoma, Mantle-Cell, Leukemia, Large Granular Lymphocytic, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, Dendritic Cell Sarcoma, Interdigitating, Primary Myelofibrosis, Intraocular Lymphoma

NCT00003941 2012-09-24

Combination Chemotherapy With or Without Peripheral Stem Cell Transplant in Treating Men With Previously Untreated Germ Cell Cancer

Phase 3 Completed

CNSGenitourinary

Teratoma, Testicular, Testicular Germ Cell Tumor, Brain Neoplasms, Mediastinal Neoplasms, Neoplasm Metastasis, Teratoma, Testicular Neoplasms, Carcinoma, Embryonal, Seminoma, Endodermal Sinus Tumor

NCT00006353 2012-09-24

Radiation Therapy With or Without Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

Phase 3 Completed

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00020839 2012-09-24

Temozolomide With or Without Radiation Therapy to the Brain in Treating Patients With Stage IV Melanoma That Is Metastatic to the Brain

Phase 3 Terminated

CNSDermatologic

Brain Neoplasms, Melanoma, Neoplasm Metastasis

NCT00104936 2012-09-24

Radiotherapy or Radiosurgery Compared With Observation Alone in Treating Patients With Newly Diagnosed, Benign Meningioma That Has Been Partially Removed by Surgery

Phase 3 Terminated

Central Nervous System Neoplasms

NCT00002840 2012-07-10

Radiation Therapy With and Without Combination Chemotherapy in Patients With Resected Anaplastic Oligodendroglioma

Phase 3 Completed

Brain Neoplasms, Glioma, Oligodendroglioma, Central Nervous System Neoplasms

NCT00002620 2012-07-02

Radiation Therapy in Treating Patients With Brain Cancer

Phase 3 Completed

Astrocytoma, Central Nervous System Neoplasms

NCT00002899 2012-07-02

Adjuvant Radiation Therapy in Treating Patients With Brain Metastases

Phase 3 Terminated

Brain Neoplasms, Neoplasm Metastasis

NCT00717210 2008-07-17

NOA-04

Phase 3 Completed

Astrocytoma, Oligodendroglioma