Clinical Trials Browser

Bone Neoplasms, Breast Neoplasms, Uterine Cervical Neoplasms, Colonic Neoplasms, Leukemia, Lymphoma, Melanoma, Sarcoma, Thyroid Neoplasms, Central Nervous System Neoplasms, Pyloric Stenosis, Hypertrophic

NCT06319027 2026-03-02

GABLE

Phase 2 Recruiting

100 enrolled

CNS

Glioblastoma

NCT02402244 2026-02-27

Project: Every Child for Younger Patients With Cancer

Recruiting

75,000 enrolled

CNSDermatologicEndocrineLymphoidMyeloidNETSarcoma

Carcinoma in Situ, Ganglioneuroma, Lymphoproliferative Disorders, Melanoma, Myeloproliferative Disorders, Neoplasms, Pheochromocytoma, Central Nervous System Neoplasms, Nephroma, Mesoblastic, Desmoid Tumors, Neuroendocrine Tumors

NCT03126916 2026-02-27

Testing the Addition of 131I-MIBG or Lorlatinib to Intensive Therapy in People With High-Risk Neuroblastoma (NBL)

Phase 3 Recruiting

750 enrolled

CNS

Neuroblastoma, Ganglioneuroblastoma

NCT04851119 2026-02-24

Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors

Phase 1/2 Recruiting

147 enrolled

CNSDermatologicGastrointestinalGenitourinaryGynecologicLymphoidSarcoma

Carcinoma, Hepatocellular, Lymphoma, Non-Hodgkin, Melanoma, Wilms Tumor, Neuroblastoma, Ovarian Neoplasms, Sarcoma, Ewing, Osteosarcoma, Colorectal Neoplasms, Endometrial Neoplasms, Hepatoblastoma, Desmoid Tumors

NCT04870944 2026-02-24

CBL0137 for the Treatment of Relapsed or Refractory Solid Tumors, Including CNS Tumors and Lymphoma

Phase 1/2 Recruiting

63 enrolled

CNSLymphoid

Diffuse Intrinsic Pontine Glioma, Lymphoma

NCT05382338 2026-02-24

A Study of Treatment for Medulloblastoma Using Sodium Thiosulfate to Reduce Hearing Loss

Phase 3 Recruiting

225 enrolled

CNS

Medulloblastoma

NCT03794349 2026-02-18

Irinotecan Hydrochloride, Temozolomide, and Dinutuximab With or Without Eflornithine in Treating Patients With Relapsed or Refractory Neuroblastoma

Phase 2 Active not recruiting

94 enrolled 14 charts

CNS

Neuroblastoma

NCT05904119 2026-02-17

LEGATO

Phase 3 Recruiting

411 enrolled

CNS

Glioblastoma

NCT06809322 2026-02-17

VIGOR

Phase 3 Recruiting

468 enrolled

CNS

Astrocytoma

NCT04743661 2026-02-05

131I-Omburtamab, in Recurrent Medulloblastoma and Ependymoma

Phase 2 Active not recruiting

62 enrolled

CNS

Ependymoma, Medulloblastoma

NCT04201457 2026-02-03

A Trial of Dabrafenib, Trametinib and Hydroxychloroquine for Patients With Recurrent LGG or HGG With a BRAF Aberration

Phase 1/2 Active not recruiting

57 enrolled

CNS

Glioma

NCT00336024 2026-01-23

Combination Chemotherapy Followed By Peripheral Stem Cell Transplant in Treating Young Patients With Newly Diagnosed Supratentorial Primitive Neuroectodermal Tumors or High-Risk Medulloblastoma

Phase 3 Completed

91 enrolled 24 charts

CNS

Medulloblastoma

NCT01175356 2026-01-23

Induction Therapy Including 131 I-MIBG and Chemotherapy in Treating Patients With Newly Diagnosed High-Risk Neuroblastoma Undergoing Stem Cell Transplant, Radiation Therapy, and Maintenance Therapy With Isotretinoin

Phase 1 Completed

99 enrolled 11 charts

CNS

Neuroblastoma, Ganglioneuroblastoma

NCT03550391 2026-01-13

Stereotactic Radiosurgery Compared With Hippocampal-Avoidant Whole Brain Radiotherapy (HA-WBRT) Plus Memantine for 5 or More Brain Metastases

Phase 3 Recruiting

206 enrolled

CNS

Brain Neoplasms

NCT03057626 2026-01-09

Late Effects After Treatment in Patients With Previously Diagnosed High-Risk Neuroblastoma

Active not recruiting

376 enrolled

CNS

Neuroblastoma

NCT04113408 2026-01-06

MENTHE

Terminated

315 enrolled

CNS

Meningioma

NCT04113395 2026-01-05

CAMOMILLE

Completed

514 enrolled

CNS

Meningioma

NCT05049148 2026-01-05

Platon

Phase NA Recruiting

50 enrolled

CNS

Brain Neoplasms, Glioma, Inflammation

NCT06858501 2025-12-31

Comparing 123I-MIBG and 18F-MFBG Imaging in Patients With Newly Diagnosed, High Risk Neuroblastoma

Phase 2 Not yet recruiting

84 enrolled

CNS

Ganglioneuroblastoma

NCT02176967 2025-12-22

Response and Biology-Based Risk Factor-Guided Therapy in Treating Younger Patients With Non-high Risk Neuroblastoma

Phase 3 Active not recruiting

621 enrolled

CNS

Neuroblastoma, Ganglioneuroblastoma

NCT06054295 2025-12-16

Somatic Mosaicism in Twins Discordant for Childhood Cancer

Recruiting

50 enrolled

CNS

Central Nervous System Neoplasms

NCT01503086 2025-12-05

Computer Training Program for Younger Patients With a Brain Tumor Who Underwent Radiation Therapy

Phase NA Active not recruiting

45 enrolled 10 charts

CNS

Brain Neoplasms

NCT03834961 2025-12-02

Larotrectinib in Treating Patients With Previously Untreated TRK Fusion Solid Tumors and TRK Fusion Relapsed Acute Leukemia

Phase 2 Active not recruiting

33 enrolled 18 charts

CNS

Central Nervous System Neoplasms

NCT03224104 2025-11-26

STEAM

Phase 1 Completed

71 enrolled 18 charts

CNS

Astrocytoma, Glioblastoma

NCT01602666 2025-11-20

Chemotherapy Followed by Radiation Therapy in Treating Younger Patients With Newly Diagnosed Localized Central Nervous System Germ Cell Tumors

Phase 2 Completed

262 enrolled 17 charts

CNS

Central Nervous System Nongerminomatous Germ Cell Tumor

NCT00904241 2025-11-13

Biomarkers in Tumor Tissue Samples From Patients With Newly Diagnosed Neuroblastoma or Ganglioneuroblastoma

Active not recruiting

10,000 enrolled

CNS

Neuroblastoma, Ganglioneuroblastoma

NCT03904862 2025-10-30

Testing the Safety and Tolerability of CX-4945 in Patients With Recurrent Medulloblastoma Who May or May Not Have Surgery

Phase 1/2 Terminated

21 enrolled

CNS

Microphthalmia, Isolated, with Coloboma 5, Medulloblastoma

NCT04402073 2025-10-23

PersoMed-I

Phase 2 Terminated

20 enrolled

CNS

Medulloblastoma

NCT03418961 2025-10-08

S1501 Dual Observational and Randomized Cohort Study of Patients With Metastatic HER-2+ Breast Cancer at Risk of Cardiac Toxicity

Phase 3 Recruiting

491 enrolled

BreastCNS

Brain Neoplasms, Breast Neoplasms, Cardiotoxicity

NCT06326190 2025-09-16

LUMEN-1

Phase 2 Recruiting

136 enrolled

CNS

Meningioma

NCT00978458 2025-09-08

Radiation Therapy With or Without Temozolomide in Treating Patients With Low-Grade Glioma

Phase 3 Active not recruiting

540 enrolled

CNS

Astrocytoma, Brain Neoplasms, Glioma, Oligodendroglioma, Central Nervous System Neoplasms, Neurotoxicity Syndromes

NCT06390579 2025-09-08

BRAIN

Completed

693 enrolled

CNS

Brain Neoplasms, Optic Atrophy, Optic Nerve Diseases, Optic Neuritis, Papilledema, Optic Neuropathy, Ischemic

NCT05934630 2025-08-11

Testing Cerebrospinal Fluid for Cell-free Tumor DNA in Children, Adolescents, and Young Adults With Brain Tumors

Suspended

300 enrolled

CNS

Choroid Plexus Carcinoma, Astrocytoma, Brain Neoplasms, Ependymoma, Glioblastoma, Medulloblastoma, Oligodendroglioma, Pinealoma, Central Nervous System Neoplasms, Rhabdoid Tumor

NCT02234050 2025-07-10