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NCT00336024 2026-01-23

Combination Chemotherapy Followed By Peripheral Stem Cell Transplant in Treating Young Patients With Newly Diagnosed Supratentorial Primitive Neuroectodermal Tumors or High-Risk Medulloblastoma

Phase 3 Completed

91 enrolled 24 charts

Medulloblastoma

NCT01175356 2026-01-23

Induction Therapy Including 131 I-MIBG and Chemotherapy in Treating Patients With Newly Diagnosed High-Risk Neuroblastoma Undergoing Stem Cell Transplant, Radiation Therapy, and Maintenance Therapy With Isotretinoin

Phase 1 Completed

99 enrolled 11 charts

Neuroblastoma, Ganglioneuroblastoma

NCT04113395 2026-01-05

CAMOMILLE

Meningioma

NCT03224104 2025-11-26

STEAM

Phase 1 Completed

71 enrolled 18 charts

Astrocytoma, Glioblastoma

NCT01602666 2025-11-20

Chemotherapy Followed by Radiation Therapy in Treating Younger Patients With Newly Diagnosed Localized Central Nervous System Germ Cell Tumors

Phase 2 Completed

262 enrolled 17 charts

Central Nervous System Nongerminomatous Germ Cell Tumor

NCT06390579 2025-09-08

BRAIN

Brain Neoplasms, Optic Atrophy, Optic Nerve Diseases, Optic Neuritis, Papilledema, Optic Neuropathy, Ischemic

NCT02234050 2025-07-10

Trabectedin for Recurrent Grade II/III Meningioma

Phase 2 Completed

90 enrolled 18 charts

Recurrent High Grade Meningioma

NCT03345095 2025-07-01

MIRAGE

Phase 3 Completed

749 enrolled 15 charts

Glioblastoma

NCT00085735 2025-01-14

Comparison of Radiation Therapy Regimens in Combination With Chemotherapy in Treating Young Patients With Newly Diagnosed Standard-Risk Medulloblastoma

Phase 3 Completed

549 enrolled 32 charts

Medulloblastoma

NCT02323880 2025-01-14

Selinexor in Treating Younger Patients With Recurrent or Refractory Solid Tumors or High-Grade Gliomas

Phase 1 Completed

59 enrolled 20 charts

Astrocytoma, Brain Neoplasms, Glioma, Lymphoma, Central Nervous System Neoplasms

NCT02975882 2025-01-14

Nanoparticle Albumin-Bound Rapamycin, Temozolomide, and Irinotecan Hydrochloride in Treating Pediatric Patients With Recurrent or Refractory Solid Tumors

Phase 1 Completed

33 enrolled 15 charts

Central Nervous System Neoplasms

NCT04737785 2024-08-27

Central Nervous System Disorders Following Hematopoietic Stem Cell Transplantation

CNSOther hematologic neoplasm

Central Nervous System Infections, Hematologic Diseases, Infections, Hematologic Neoplasms

NCT01798004 2024-07-15

Busulfan, Melphalan, and Stem Cell Transplant After Chemotherapy in Treating Patients With Newly Diagnosed High-Risk Neuroblastoma

Phase 1 Completed

150 enrolled 9 charts

Neuroblastoma, Ganglioneuroblastoma

NCT00003375 2024-07-09

Observation or Radiation Therapy With or Without Combination Chemotherapy in Treating Patients With Low-Grade Glioma

Phase 2/3 Completed

Astrocytoma, Oligodendroglioma, Central Nervous System Neoplasms

NCT00114140 2024-07-08

Temozolomide and Radiation Therapy in Treating Patients With Gliomas

Phase 2 Completed

136 enrolled 9 charts

Astrocytoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms

NCT03770468 2024-03-08

Molecular Genetic, Host-derived and Clinical Determinants of Long-term Survival in Glioblastoma

Glioblastoma

NCT01606878 2024-01-05

Crizotinib and Combination Chemotherapy in Treating Younger Patients With Relapsed or Refractory Solid Tumors or Anaplastic Large Cell Lymphoma

Phase 1 Completed

46 enrolled 24 charts

Neuroblastoma, Lymphoma, Large-Cell, Anaplastic

NCT02808650 2023-12-20

Prexasertib in Treating Pediatric Patients With Recurrent or Refractory Solid Tumors

Phase 1 Completed

30 enrolled 16 charts

Central Nervous System Neoplasms

NCT00895622 2023-09-08

Observation or Radiation Therapy in Treating Patients With Grade I, Grade II, or Grade III Meningioma

Phase 2 Completed

244 enrolled 15 charts

Brain Neoplasms, Meningioma, Central Nervous System Neoplasms

NCT00482677 2023-08-22

Radiation Therapy With or Without Temozolomide in Treating Older Patients With Newly Diagnosed Glioblastoma Multiforme

Phase 3 Completed

562 enrolled 11 charts

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT01259869 2023-08-22

A Study of PX-866 in Patients With Glioblastoma Multiforme at Time of First Relapse or Progression

Phase 2 Completed

34 enrolled 7 charts

Glioblastoma

NCT00387400 2023-08-04

Temozolomide + Everolimus in Newly Diagnosed, Recurrent, or Progressive Malignant Glioblastoma Multiforme

Phase 1 Completed

Brain Neoplasms, Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT02619864 2023-08-04

mTORC1/mTORC2 Kinase Inhibitor AZD2014 in Previously Treated Glioblastoma Multiforme

Phase 1 Completed

Glioblastoma

NCT00080938 2023-06-29

Temozolomide and Radiation Therapy in Treating Patients With Brain Metastasis Secondary to Non-Small Cell Lung Cancer

Phase 2 Completed

26 enrolled 8 charts

Adenocarcinoma of Lung, Brain Neoplasms, Adenocarcinoma, Bronchiolo-Alveolar, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasm Metastasis

NCT00003308 2023-06-22

Radiation Therapy in Treating Patients With Newly Diagnosed Brain Metastases From Kidney Cancer, Melanoma, or Sarcoma

Phase 2 Completed

CNSDermatologicGenitourinaryGynecologicSarcoma

Brain Neoplasms, Carcinoma, Renal Cell, Chondrosarcoma, Kidney Neoplasms, Melanoma, Neoplasm Metastasis, Ovarian Neoplasms, Sarcoma, Osteosarcoma, Neuroectodermal Tumors, Primitive, Peripheral

NCT00003309 2023-06-22

Combination Chemotherapy Plus Radiation Therapy in Treating Adult Patients With Brain Cancer

Phase 2 Completed

Ependymoma, Medulloblastoma, Central Nervous System Neoplasms

NCT00028678 2023-06-18

Dalteparin and Radiation Therapy in Treating Patients With Newly Diagnosed Supratentorial Glioblastoma Multiforme

Phase 2 Completed

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00002520 2023-06-15

Physician-Initiated Stop-Smoking Program for Patients Receiving Treatment for Early-Stage Cancer

Phase NA Completed

BreastCNSDermatologicGastrointestinalGenitourinaryHead & NeckLymphoidOther hematologic neoplasmThoracic

Testicular Germ Cell Tumor, Squamous Cell Carcinoma of Head and Neck, Urinary Bladder Neoplasms, Breast Neoplasms, Burkitt Lymphoma, Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Head and Neck Neoplasms, Hodgkin Disease, Immunoblastic Lymphadenopathy, Lung Neoplasms, Lymphoma, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Mycosis Fungoides, Prostatic Neoplasms, Rectal Neoplasms, Sezary Syndrome, Testicular Neoplasms, Tobacco Use Disorder, Colorectal Neoplasms, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, Large B-Cell, Diffuse, Lymphoma, T-Cell, Cutaneous, Lymphoma, Large-Cell, Anaplastic, Esthesioneuroblastoma, Olfactory, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, Intraocular Lymphoma

NCT00082797 2023-06-15

High-Dose Methotrexate and Leucovorin in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

Phase 2 Completed

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT04091503 2023-04-25

Evaluate the Safety and Effectiveness of Intranasal Administration of Temozolomide in Patients With Glioblastoma

Phase 1 Completed

Glioma, Gliosarcoma

NCT00033293 2023-04-18

Cyclophosphamide and Prednisone With or Without Immunoglobulin in Treating Abnormal Muscle Movement in Children With Neuroblastoma

Phase 3 Completed

53 enrolled 14 charts

Neuroblastoma

NCT00100802 2023-02-15

Radiation Therapy, Temozolomide, and Lomustine in Treating Young Patients With Newly Diagnosed Gliomas

Phase 2 Completed

118 enrolled 8 charts

Astrocytoma, Glioblastoma, Spinal Cord Neoplasms, Central Nervous System Neoplasms, Gliosarcoma

NCT02017964 2023-01-09

Combination Chemotherapy in Treating Younger Patients With Newly Diagnosed, Non-metastatic Desmoplastic Medulloblastoma

Phase 2 Completed

26 enrolled 14 charts

CNSDermatologic

Basal Cell Nevus Syndrome, Medulloblastoma

NCT01730950 2022-12-29

Bevacizumab With or Without Radiation Therapy in Treating Patients With Recurrent Glioblastoma

Phase 2 Completed

182 enrolled 19 charts

Brain Neoplasms, Glioblastoma, Gliosarcoma

NCT01062399 2022-06-09

RTOG 0913

Phase 1/2 Completed

279 enrolled 14 charts

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00567567 2022-04-28

Comparing Two Different Myeloablation Therapies in Treating Young Patients Who Are Undergoing a Stem Cell Transplant for High-Risk Neuroblastoma

Phase 3 Completed

665 enrolled 26 charts

Neuroblastoma

NCT02452554 2022-01-13

Lorvotuzumab Mertansine in Treating Younger Patients With Relapsed or Refractory Wilms Tumor, Rhabdomyosarcoma, Neuroblastoma, Pleuropulmonary Blastoma, Malignant Peripheral Nerve Sheath Tumor, or Synovial Sarcoma

Phase 2 Completed

62 enrolled 15 charts

CNSGenitourinarySarcoma

Pleuropulmonary blastoma, Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Synovial, Neurofibrosarcoma

NCT03387020 2021-08-27

Ribociclib and Everolimus in Treating Children With Recurrent or Refractory Malignant Brain Tumors

Phase 1 Completed

22 enrolled 16 charts

Familial ependymoma, Diffuse Intrinsic Pontine Glioma, Glioma, Medulloblastoma, Rhabdoid Tumor

NCT00499616 2021-07-06

Combination Chemotherapy and Surgery With or Without Isotretinoin in Treating Young Patients With Neuroblastoma

Phase 3 Completed

464 enrolled 25 charts

Neuroblastoma

NCT01290939 2021-02-15

Bevacizumab and Lomustine for Recurrent GBM

Phase 3 Completed

Brain Neoplasms, Cognition Disorders, Glioblastoma

NCT00006386 2020-10-22

Radiation Therapy Followed by Carmustine in Treating Patients Who Have Supratentorial Glioblastoma Multiforme

Phase 2 Completed

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00006388 2020-10-22

Radiation Therapy and Tamoxifen in Treating Adults With Newly Diagnosed Supratentorial Glioblastoma Multiforme

Phase 2 Completed

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00007007 2020-10-22

Evaluation of Memory Skills in Patients Receiving Radiation Therapy for Brain Metastases

Phase NA Completed

Brain Neoplasms, Neoplasm Metastasis, Radiation Injuries

NCT00031967 2020-10-22

Melatonin and Radiation Therapy in Treating Patients With Brain Metastases

Phase 2 Completed

Brain Neoplasms, Neoplasm Metastasis, Radiation Injuries

NCT00939770 2020-06-09

Crizotinib in Treating Younger Patients With Relapsed or Refractory Solid Tumors or Anaplastic Large Cell Lymphoma

Phase 1/2 Completed

122 enrolled 24 charts 2 FDA

Neuroblastoma, Lymphoma, Large-Cell, Anaplastic

NCT01154816 2020-05-13

Alisertib in Treating Young Patients With Recurrent or Refractory Solid Tumors or Leukemia

Phase 2 Completed

118 enrolled 24 charts

CNSGastrointestinalLymphoidOther hematologic neoplasmSarcoma

Neuroblastoma, Osteosarcoma, Hepatoblastoma, Neuroectodermal Tumors, Primitive, Peripheral, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT00003372 2020-04-08

Topotecan in Treating Patients With Recurrent Brain Tumors

Phase 2 Completed

Brain Neoplasms, Glioma, Oligodendroglioma, Central Nervous System Neoplasms

NCT00036660 2020-04-06

SarCNU in Treating Patients With Recurrent Malignant Glioma

Phase 2 Completed

Astrocytoma, Brain Neoplasms, Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT03015701 2019-12-23

S9005 Mifepristone in Meningioma

Phase 3 Completed

Meningioma

NCT03722355 2019-11-12

Hyperfractionated RT With BCNU Versus Conventional RT With BCNU for Supratentorial Malignant Glioma

Phase 3 Completed

Astrocytoma, Glioblastoma, Glioma