Clinical Trials

313 enrolled

Legius syndrome, Neurofibroma, Neurofibromatosis 1

NCT04755205 2026-01-29

A Natural History Study of Children and Adults With Olfactory Neuroblastoma

525 enrolled

Esthesioneuroblastoma, Olfactory

NCT02544022 2026-01-08

Development and Validation of Patient Reported Outcome (PRO) Measures for Individuals With Neurofibromatosis 1 (NF1) and Plexiform Neurofibromas (pNFs)

476 enrolled

Neurofibromatosis 1, Neurofibroma, Plexiform

NCT03251989 2026-01-08

Rare CNS Tumors Outcomes &Risk

326 enrolled

Brain Neoplasms, Ependymoma, Glioma, Medulloblastoma, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Neuroectodermal Tumors, Primitive, Rhabdoid Tumor

NCT00083512 2025-12-31

Collection of Blood and Urine Samples in Patients Receiving Radiation Therapy for Glioblastoma Multiforme

200 enrolled

Glioblastoma

NCT06880991 2025-10-06

Development of Patient-Reported Outcome Measures Assessing Tumor Visibility and Appearance Concerns in Neurofibromatosis Type 1: A Qualitative Study

110 enrolled

Neurofibroma, Neurofibromatosis 1

NCT06222203 2025-09-26

Surveillance for Malignant Transformation of Neurofibromatosis Type 1 (NF1) Related Peripheral Nerve Sheath Tumors (PNST)

225 enrolled

CNSSarcoma

Neurofibroma, Neurofibromatosis 1, Nerve Sheath Neoplasms, Neurofibroma, Plexiform, Neurofibrosarcoma

NCT04774289 2024-09-19

Incidence of Malignant Peripheral Nerve Sheath Tumor (MPNST) Development in Participants With Neurofibromatosis Type 1 (NF1) Receiving and Not Receiving Medical Therapies Directed at Plexiform Neurofibromas (PN)

296 enrolled

Neurofibromatosis 1, Peripheral Nervous System Neoplasms

NCT01445314 2024-08-16

Analysis of Data Collected From Individuals Administered Neurobehavioral Assessments

598 enrolled

Behavior, Brain Neoplasms, Neurofibromatosis 1

NCT01702922 2024-07-31

Relationship Stressors in Parents of Children With Cancer or Neurofibromatosis Type 1 (NF1)

262 enrolled

Parents of Children With Cancer

NCT01639950 2024-06-21

Validating Pain Scales in Children and Young Adults

CNSClassical hematologyOther hematologic neoplasm

252 enrolled

Anemia, Sickle Cell, Leukemia, Pain, Neurofibromatoses

NCT04879160 2024-03-22

Systematically Assessing Changes in Plexiform Neurofibroma Related Disfigurement From Photographs of Subjects With Neurofibromatosis Type 1 on a Phase 2 Clinical Trial

52 enrolled

Neurofibromatosis 1

NCT00067821 2023-06-13

Comparison of PET and Proton MRS Imaging to Evaluate Pediatric Brain Tumor Activity

79 enrolled

Brain Neoplasms

NCT00339352 2020-12-04

A Family Study of Adults With Glioma

1,871 enrolled

Glioma

NCT00026780 2020-10-08

Eligibility Screening for a NCI Pediatric Oncology Branch Research Study

CNSLymphoidOther hematologic neoplasmSarcoma

1,720 enrolled

Neoplasms, Neuroblastoma, Neurofibromatosis 1, Sarcoma, Ewing, Osteosarcoma, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT00001686 2020-09-10

Evaluation, Treatment, and Natural History of Children and Young Adults With Cancer or Rare Diseases

CNSLymphoidOther hematologic neoplasmSarcoma

482 enrolled

Brain Neoplasms, Leukemia, Lymphoma, Neoplasms, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Neuroectodermal Tumors

NCT02911155 2020-05-05

Cancer and Other Disease Risks in U.S. Nuclear Medicine Technologists

229 enrolled

BreastCNSHead & Neck

Brain Neoplasms, Breast Neoplasms, Thyroid Neoplasms

NCT00006435 2020-05-04

Study of Plexiform Neurofibromas in Neurofibromatosis Type 1

24 enrolled

Neurofibroma, Plexiform

NCT02743481 2020-04-20

Early Life Exposures in Agriculture

CNSGenitourinaryLymphoidOther hematologic neoplasm

60,000 enrolled

Brain Neoplasms, Leukemia, Lymphoma, Neoplasms, Testicular Neoplasms

NCT00824278 2019-12-17

The Use of a Distress Thermometer in a Pediatric Research Setting: An Exploratory Pilot Study

289 enrolled

Neoplasms, HIV Infections, Neurofibromatoses

NCT01222728 2019-12-17

Using Positron Emission Tomography to Predict Intracranial Tumor Growth in Neurofibromatosis Type II Patients

5 enrolled

Neoplasms, Nervous System Diseases, Neuroma, Acoustic, Vestibular Diseases, Neurofibromatosis 2, Neurofibromatoses

NCT00340522 2019-12-16

Childhood Cancer and Plexiform Neurofibroma Tissue Microarray for Molecular Target Screening and Clinical Drug Development

20 enrolled

CNSSarcoma

Brain Neoplasms, Neoplasms, Neoplasms, Germ Cell and Embryonal, Sarcoma, Neurofibroma, Plexiform

NCT00684398 2019-12-16

Adaptation and Quality of Life Among Adults With Neurofibromatosis Type I

645 enrolled

Neurofibromatosis 1

NCT00009035 2019-12-12

Natural History of Patients With Brain and Spinal Cord Tumors

3,050 enrolled

Astrocytoma, Glioblastoma, Glioma, Medulloblastoma, Neoplasms, Oligodendroglioma, Central Nervous System Neoplasms

NCT01117155 2019-12-12

A Pilot Study Evaluating 18F-L-Thymidine (FLT) PET Imaging in Children With Gliomas

Withdrawn

Astrocytoma, Brain Neoplasms, Ependymoma, Glioblastoma, Glioma, Neuroectodermal Tumors, Primitive

NCT00031538 2019-12-09

Genetic Analysis of Brain Tumors

674 enrolled

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma

NCT01251913 2019-12-03

A Pilot Study of Inpatient Hospice With Procurement of Brain Tumor Tissue on Expiration for Research Purposes

7 enrolled

Astrocytoma, Brain Neoplasms, Ependymoma, Glioma, Pinealoma, Neuroectodermal Tumors, Primitive

NCT02692898 2019-11-19

Biomarker Analysis of Central Nervous System Tumors

12 enrolled

Brain Neoplasms, Central Nervous System Neoplasms

NCT00035373 2019-11-07

Eligibility Screening of Patients With Central Nervous System Tumors for the National Cancer Institute s (NCI) Clinical Research Protocols

767 enrolled

CNSSarcoma

Astrocytoma, Neoplasms, Oligodendroglioma, Central Nervous System Neoplasms, Gliosarcoma

NCT00001574 2019-05-08

A Pilot Study of 1H-Nuclear Magnetic Resonance Spectroscopic Imaging in Pediatric Patients With Primary and Metastatic Brain Tumors

40 enrolled

Brain Neoplasms

NCT00001807 2019-04-24

(1)H-Nuclear Magnetic Resonance Spectroscopic Imaging of the Brain in Patients Who Receive Neurotoxic Therapy

50 enrolled

Brain Neoplasms, Neurotoxicity Syndromes

NCT02153931 2019-01-31

Internet Support Group for Parents of a Child With Neurofibromatosis Type 1

33 enrolled

Anxiety Disorders, Depression, Neurofibromatosis 1

NCT01281982 2018-07-05

(11C)dLop as a Marker of P-Glycoprotein Function in Patients With Gliomas

2 enrolled

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma

NCT00339300 2018-04-05

A Case-Referent Study of Brain Tumors in Adults

1,581 enrolled

Brain Neoplasms, Glioma

NCT00923468 2017-07-02

Pharmacokinetic Studies Participation Survey

CNSOther hematologic neoplasm

25 enrolled

Brain Neoplasms, Leukemia

NCT00923650 2017-07-02

Informed Consent in Pediatric Cancer Trials

CNSOther hematologic neoplasmSarcoma

1 enrolled

Brain Neoplasms, Leukemia, Neuroblastoma, Sarcoma, Ewing, Osteosarcoma

NCT00278239 2013-09-20

Quality of Life in Patients Who Have Undergone Previous Treatment for Primitive Neuroectodermal Tumors

Unknown

CNSDermatologicGastrointestinalGenitourinaryLymphoidOther hematologic neoplasm

Central Nervous System Neoplasms

NCT00757614 2013-08-26

Study of Genes and Environment in Patients With Cancer in East Anglia, Trent, or West Midlands Regions of the United Kingdom

Unknown

14,000 enrolled

Uveal Melanoma, Astrocytoma, Urinary Bladder Neoplasms, Brain Neoplasms, Carcinoma, Renal Cell, Craniopharyngioma, Esophageal Neoplasms, Hodgkin Disease, Kidney Neoplasms, Lymphoma, Lymphoma, Non-Hodgkin, Melanoma, Meningeal Neoplasms, Neoplasms, Germ Cell and Embryonal, Pancreatic Neoplasms, Pinealoma, Lymphoma, T-Cell, Cutaneous, Lymphoma, AIDS-Related, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Nephroma, Mesoblastic, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, Intraocular Lymphoma

NCT00891722 2013-08-26

Tumor Tissue, Blood Samples, and Family History in Predicting Tumor Development and Response to Treatment in Young Patients With Low-Grade Glioma

Unknown

900 enrolled

Astrocytoma, Oligodendroglioma, Central Nervous System Neoplasms, Optic Nerve Glioma

NCT00340054 2012-03-08

Developing Interview Questions to Estimate Workplace Exposure to Electric and Magnetic Fields

108 enrolled

Brain Neoplasms, Central Nervous System Neoplasms

NCT00001148 2008-03-04

Detecting Malignant Brain Tumor Cells in the Bloodstream During Surgery to Remove the Tumor

25 enrolled

Astrocytoma, Glioblastoma, Glioma, Neoplastic Cells, Circulating, Neoplasm Metastasis

NCT00001171 2008-03-04

Evaluation of Factors in Human Brain Tumors