Clinical Trials Browser

Thyroid Cancer, Papillary, Carcinoma, Non-Small-Cell Lung, Gastrointestinal Neoplasms, Glioma, Histiocytosis, Langerhans-Cell, Laryngeal Neoplasms, Lymphoproliferative Disorders, Multiple Myeloma, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Ovarian Neoplasms, Colorectal Neoplasms, Hematologic Neoplasms, Erdheim-Chester Disease, Thyroid Carcinoma, Anaplastic

NCT07076498 2026-02-25

Engineered HSV-1 M032 for the Treatment of Children and Adults With Newly Diagnosed Diffuse Midline Glioma After Standard of Care Radiation

Phase 1 Not yet recruiting

20 enrolled

CNS

Diffuse Intrinsic Pontine Glioma, Glioma

NCT07428616 2026-02-24

A Study of Zanzalintinib in Participants With Recurrent or Progressive Meningioma

Phase 2 Not yet recruiting

100 enrolled

CNS

Brain Neoplasms, Meningioma

NCT07431216 2026-02-24

A Phase 1b/2a Study to Evaluate the Safety, Pharmacokinetics, and Objective Response of STAR-001 (LP-184) in Combination With Spironolactone in Supratentorial Glioblastoma at First Progression

Phase 1/2 Not yet recruiting

68 enrolled

CNS

Glioblastoma

NCT07428213 2026-02-23

PIVIM

Phase NA Not yet recruiting

40 enrolled

CNS

Meningioma

NCT05676489 2026-02-20

MeFAMP for Imaging System A Amino Acid Transport in Primary and Metastatic Brain Tumors

Phase EARLY_PHASE1 Not yet recruiting

28 enrolled

CNS

Glioma

NCT07271966 2026-02-20

BALANCE

Phase NA Not yet recruiting

50 enrolled

CNS

Brain Neoplasms

NCT07422896 2026-02-20

Bvax

Phase 1 Not yet recruiting

25 enrolled

CNS

Glioblastoma

NCT07424092 2026-02-20

PED-DNX2401

Phase 2 Not yet recruiting

39 enrolled

CNS

Ependymoma, Glioma, Recurrence

NCT06448286 2026-02-19

PH Weighted Chemical Exchange Saturation Transfer MRI-Based Surgical Resection to Improve Survival in Patients With Glioblastoma

Phase 3 Not yet recruiting

60 enrolled

CNS

Glioblastoma

NCT07384884 2026-02-19

SLITT-GBM

Phase NA Not yet recruiting

12 enrolled

CNS

Brain Neoplasms

NCT07375992 2026-02-18

MELODY

Phase NA Not yet recruiting

35 enrolled

CNS

Glioblastoma

NCT07415668 2026-02-17

MENTOR

Phase NA Not yet recruiting

30 enrolled

CNS

Brain Neoplasms, Neoplasm Metastasis

NCT07218367 2026-02-13

Phase I Trial of pH Resections of GBM at VA

Phase 1 Not yet recruiting

12 enrolled

CNS

Glioblastoma, Glioma

NCT07278440 2026-02-13

An Exercise Intervention for Improving Mental and Physical Health in Patients With Primary Brain Tumors and Their Caregivers, ET-NEURO Trial

Phase NA Not yet recruiting

36 enrolled

CNS

Brain Neoplasms

NCT07407803 2026-02-12

Evaluation of TQ-B3234 Capsules in Patients With Symptomatic, Non-Surgical Type 1 Neurofibromatosis-Associated Plexiform Neurofibromas

Phase 3 Not yet recruiting

177 enrolled

CNS

Neurofibroma, Plexiform

NCT05253131 2026-02-11

Trial of Selumetinib and Bromodomain Inhibitor With Durvalumab for Sarcomas

Phase 2 Not yet recruiting

41 enrolled

CNSSarcoma

Neurofibromatosis 1, Sarcoma, Neurofibrosarcoma

NCT07398170 2026-02-09

BIOLIMEN-1

Phase NA Not yet recruiting

15 enrolled

CNS

Meningioma, Neoplastic Cells, Circulating, Neoplasm Recurrence, Local

NCT07211737 2026-02-06

NKG2D.Zeta-NK Cell Conditioning With C7R.GD2.CAR-T Cells for Patients With Relapsed or Refractory Osteosarcoma or Neuroblastoma

Phase 1 Not yet recruiting

27 enrolled

CNSSarcoma

Neuroblastoma, Osteosarcoma

NCT07387666 2026-02-06

Imaging Acetadote Metabolism in Glioblastoma

Phase EARLY_PHASE1 Not yet recruiting

10 enrolled

CNS

Glioblastoma

NCT07392957 2026-02-06

Safety and Efficacy of CTX-009 With or Without CTX-471 for Recurrent Glioblastoma

Phase 1/2 Not yet recruiting

54 enrolled

CNS

Glioblastoma

NCT07390539 2026-02-05

B7-H3.CD28Z.CART in CNS Neoplasms

Phase 1 Not yet recruiting

70 enrolled

CNS

Brain Neoplasms, Ependymoma, Medulloblastoma, Meningeal Neoplasms, Pinealoma, Central Nervous System Neoplasms, Neuroectodermal Tumors, Primitive, Rhabdoid Tumor

Clinical Trials

Novel Indenoisoquinolone CMYC/TOPOISOMERASE 1 Inhibitor (LMP744) in Recurrent Glioblastoma

Testing the Combination of Anti-cancer Drugs Actimab-A and Cemiplimab (REGN2810) to Improve Outcomes for Patients With Recurrent Glioblastoma

Testing the Addition of Iberdomide to Therapy in People With Neuroblastoma That Has Come Back, Not Responded to Treatment, or Gotten Worse

Oliceridine Versus Sufentanil for Postoperative Nausea in Cerebellopontine Angle Surgery

Andro-iGlio

A Study on the Novel Oncolytic Virus Combined With PD-1 Inhibitor in the Treatment of Recurrent High-grade Glioma

VANGUARD

Neuromodulation-Induced Cortical Prehabilitation in High Grade Glioma Near the Motor Pathway: Cortical Plasticity Assessed by Navigated Transcranial Magnetic Stimulation (nTMS)

NF113

CIPHER

Asciminib With or Without Sildenafil for Brain Tumors

A Phase 1 Safety and Dose Finding Study of GLIX1 in Adults With Recurrent or Progressive High-grade Glioma

PRiME II

Inflammation in Primary and Secondary Malignancies of the Central Nervous System Using [C-11]-CS1P1

INSIGHT MRL

BERLIN

Trastuzumab Deruxtecan + Stereotactic Radiosurgery (SRS) in HER2+ Breast Cancer Brain Metastases

A Phase I Study of FZ-AD005 in Patients With High-Grade Glioma (HGG)

Temporally-Modulated Pulsed Radiation Therapy Versus Standard Radiation Therapy for the Treatment of Newly Diagnosed, IDH Wildtype, MGMT-Unmethylated Glioblastoma

ADePT

T-BRAIN

A Single-Arm, Open-Label, Phase II Clinical Study of Utidelone and Bevacizumab With or Without Etoposide in Patients With Brain Metastases From Malignant Solid Tumors

A Study to Assess a Medicine Called Tovorafenib in Japanese Children and Young Adults With Brain Tumours

Direct Comparison of Ga-68-DOTATATE and Ga-68-DOTATOC

Window Trial of Fluorescently Labeled Nivolumab-IRDye800 (Nivo800) in High Grade Glioma (HGG)

Fluorescence-Guided Imaging of Brain Tumors: A Safety Study Using SBK2-ICG

PRC

NEURO-PRO-GLIO

DETERMINE

Engineered HSV-1 M032 for the Treatment of Children and Adults With Newly Diagnosed Diffuse Midline Glioma After Standard of Care Radiation

A Study of Zanzalintinib in Participants With Recurrent or Progressive Meningioma

A Phase 1b/2a Study to Evaluate the Safety, Pharmacokinetics, and Objective Response of STAR-001 (LP-184) in Combination With Spironolactone in Supratentorial Glioblastoma at First Progression

PIVIM

MeFAMP for Imaging System A Amino Acid Transport in Primary and Metastatic Brain Tumors

BALANCE

Bvax

PED-DNX2401

PH Weighted Chemical Exchange Saturation Transfer MRI-Based Surgical Resection to Improve Survival in Patients With Glioblastoma

SLITT-GBM

MELODY

MENTOR

Phase I Trial of pH Resections of GBM at VA

An Exercise Intervention for Improving Mental and Physical Health in Patients With Primary Brain Tumors and Their Caregivers, ET-NEURO Trial

Evaluation of TQ-B3234 Capsules in Patients With Symptomatic, Non-Surgical Type 1 Neurofibromatosis-Associated Plexiform Neurofibromas

Trial of Selumetinib and Bromodomain Inhibitor With Durvalumab for Sarcomas

BIOLIMEN-1

NKG2D.Zeta-NK Cell Conditioning With C7R.GD2.CAR-T Cells for Patients With Relapsed or Refractory Osteosarcoma or Neuroblastoma

Imaging Acetadote Metabolism in Glioblastoma

Safety and Efficacy of CTX-009 With or Without CTX-471 for Recurrent Glioblastoma

B7-H3.CD28Z.CART in CNS Neoplasms