Clinical Trials

Anemia, Neoplasm Metastasis, Neoplasms

NCT03194542 2023-08-24

A Safety and Efficacy Study to Evaluate Luspatercept in Subjects With Myeloproliferative Neoplasm-associated Myelofibrosis Who Have Anemia With and Without Red Blood Cell-transfusion Dependence

Classical hematologyMyeloid

95 enrolled 32 charts

Anemia, Primary Myelofibrosis

NCT01583218 2023-08-07

APEX

7,513 enrolled 18 charts 1 FDA

Venous Thromboembolism

NCT03036813 2023-07-27

GBT_HOPE

449 enrolled 17 charts 1 FDA

Anemia, Sickle Cell

NCT03020160 2023-01-11

HAVEN 4

48 enrolled 44 charts 1 FDA

Classical hematologyMyeloidOther hematologic neoplasm

Hemophilia A

NCT01957176 2022-12-30

A Rollover Study to Provide Continued Treatment With Eltrombopag

Phase 4 Completed

22 enrolled 9 charts

Myelodysplastic Syndromes, Thrombocytopenia, Leukemia, Myeloid, Acute, Purpura, Thrombocytopenic, Idiopathic

NCT02847637 2022-11-16

HAVEN 3

152 enrolled 46 charts 1 FDA

Hemophilia A

NCT01736683 2022-10-24

Study of Sotatercept for the Treatment of Anemia in low-or Intermediate-1 Risk Myelodysplastic Syndromes (MDS) or Non-proliferative Chronic Myelomonocytic Leukemia (CMML)

Classical hematologyMyeloidOther hematologic neoplasm

74 enrolled 33 charts

Anemia, Myelodysplastic Syndromes, Leukemia, Myelomonocytic, Chronic

NCT04076943 2022-06-03

Evaluation of Efficacy and Safety of Roxadustat for the Treatment of Chemotherapy Induced Anemia

92 enrolled 18 charts

Anemia

NCT02631070 2021-12-17

MEDALIST

229 enrolled 36 charts 2 FDA

Classical hematologyMyeloid

Anemia, Myelodysplastic Syndromes

NCT02964325 2021-08-19

MIPLATE

Phase NA Terminated

422 enrolled 24 charts

Classical hematologyOther hematologic neoplasm

Thrombocytopenia, Hematologic Neoplasms

NCT02622321 2021-06-24

HAVEN 1

113 enrolled 45 charts 1 FDA

Hemophilia A

NCT02795767 2021-06-02

HAVEN 2

88 enrolled 65 charts 1 FDA

Classical hematologyMyeloid

Hemophilia A

NCT01773187 2020-09-29

Pacritinib Versus Best Available Therapy to Treat Myelofibrosis

Phase 3 Terminated

327 enrolled 11 charts

Anemia, Bone Marrow Diseases, Hematologic Diseases, Myeloproliferative Disorders, Polycythemia Vera, Splenomegaly, Thrombocythemia, Essential, Thrombocytopenia, Primary Myelofibrosis

NCT01179217 2020-08-19

A Phase III Safety and Efficacy Study of L-Glutamine to Treat Sickle Cell Disease or Sickle βo-thalassemia

230 enrolled 19 charts 1 FDA

Vaso-Occlusive Crises, Anemia, Sickle Cell

NCT02516579 2020-03-19

ESCORT-HU

1,906 enrolled 9 charts 1 FDA

Anemia, Sickle Cell

NCT01895361 2020-01-31

SUSTAIN

198 enrolled 18 charts 1 FDA

Anemia, Sickle Cell, Priapism

NCT00628251 2019-12-05

ICEBERG 3

Classical hematologyGynecologic

97 enrolled 22 charts

Fanconi Anemia, Complementation Group D1, Ovarian Neoplasms

NCT02555878 2019-09-12

A Study to Evaluate the Efficacy and Safety of Rivaroxaban Venous Thromboembolism (VTE) Prophylaxis in Ambulatory Cancer Participants

841 enrolled 24 charts

Neoplasms, Venous Thromboembolism

NCT01890746 2019-09-11

A Safety and Efficacy Study of Eltrombopag in Subjects With AML

Classical hematologyOther hematologic neoplasm

148 enrolled 42 charts

Leukemia, Thrombocytopenia, Leukemia, Myeloid, Acute

NCT00952380 2019-04-16

Fragmin for the Treatment of Acute VTE in Pediatric Cancer Patients

38 enrolled 30 charts

Venous Thromboembolism

NCT01295710 2019-04-09

Study of US-ATG-F to Prevent Chronic Graft Versus Host Disease (GVHD)

Classical hematologyLymphoidMyeloidOther hematologic neoplasm

260 enrolled 26 charts

Anemia, Refractory, with Excess of Blasts, Myelodysplastic Syndromes, Leukemia, Myeloid, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT02073682 2019-03-06

Cancer Venous Thromboembolism (VTE)

1,046 enrolled 24 charts

BreastClassical hematologyGastrointestinalGenitourinaryGynecologicSarcomaThoracic

Neoplasms, Pulmonary Embolism, Venous Thrombosis, Venous Thromboembolism

NCT01286987 2019-01-10

Study of Talazoparib, a PARP Inhibitor, in Patients With Advanced or Recurrent Solid Tumors

Phase 1 Completed

113 enrolled 39 charts

Fanconi Anemia, Complementation Group D1, Carcinoma, Ovarian Epithelial, Breast Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Sarcoma, Ewing, Small Cell Lung Carcinoma

NCT02389621 2018-10-30

L-PLUS 2

215 enrolled 24 charts 1 FDA

Thrombocytopenia

NCT01340976 2018-10-03

A Phase 1 Study of LY2787106 in Cancer and Anemia

Phase 1 Completed

33 enrolled 18 charts

Anemia

NCT02761642 2018-08-24

A Study to Evaluate Efficacy and Safety of Epoetin Beta (NeoRecormon®) in Anemic Participants With Breast Cancer Undergoing Chemotherapy

200 enrolled 13 charts

Anemia

NCT02178475 2018-07-23

Prospective Observational Study of Febrile Neutropenia (FN) and Pegfilgrastim Primary Prophylaxis in Breast Cancer and Non-Hodgkin's Lymphoma Patients Receiving High (>20%) FN-risk Chemotherapy

943 enrolled 28 charts

Breast Neoplasms, Chemotherapy-Induced Febrile Neutropenia

NCT00338286 2018-03-19

A Study of Epoetin Alfa Plus Standard Supportive Care Versus Standard Supportive Care Only in Anemic Patients With Metastatic Breast Cancer Receiving Standard Chemotherapy

2,098 enrolled 12 charts

Anemia, Breast Neoplasms, Neoplasm Metastasis

NCT00236951 2018-02-20

Intravenous (IV) Iron vs. No Iron as the Treatment of Anemia in Cancer Patients Undergoing Chemotherapy and Erythropoietin Therapy

224 enrolled 9 charts

Anemia, Neoplasms

NCT00911170 2017-12-29

PAVES: Pegfilgrastim Anti-vascular Endothelial Growth Factor (VEGF) Evaluation Study

Classical hematologyGastrointestinal

847 enrolled 21 charts

Colonic Neoplasms, Fever, Neoplasms, Neutropenia, Rectal Neoplasms, Colorectal Neoplasms, Febrile Neutropenia

NCT00717366 2017-09-08

Study to Determine Optimum Intravenous Starting Dose of MIRCERA for Treatment of Pediatric Participants With Anemia and Chronic Kidney Disease on Hemodialysis

64 enrolled 15 charts 1 FDA

Renal Anemia

NCT00711958 2017-09-05

Study to Assess the Efficacy and Safety of HX575 in the Treatment of Chemotherapy Associated Anemia in Cancer Patients

114 enrolled 10 charts

Anemia

NCT02732327 2017-07-21

Comparative Study of Ceftazidime-Avibactam Versus Standard of Care as Therapy in Febrile Neutropenic Adults With Cancer

Phase 2 Terminated

2 enrolled 2 charts

Neoplasms, Febrile Neutropenia

NCT01440374 2017-06-05

ASPIRE

Classical hematologyMyeloidOther hematologic neoplasm

162 enrolled 24 charts

Myelodysplastic Syndromes, Myeloproliferative Disorders, Thrombocytopenia, Leukemia, Myeloid, Acute

NCT02767765 2017-04-04

A Study of Recombinant Human Erythropoietin Beta (NeoRecormon) in Anemic Cancer Participants Treated With Chemotherapy

61 enrolled 11 charts

Anemia

NCT01444456 2017-03-20

Assessment of Quality of Life in Patients With Symptomatic Chemotherapy-induced Anaemia

BreastClassical hematologyGastrointestinalGenitourinaryGynecologicThoracic

1,262 enrolled 14 charts

Anemia, Urinary Bladder Neoplasms, Breast Neoplasms, Esophageal Neoplasms, Kidney Neoplasms, Lung Neoplasms, Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms

NCT01444417 2017-02-09

Safety and Efficacy Study of Romiplostim to Treat Immune Thrombocytopenia (ITP) in Pediatric Patients

62 enrolled 16 charts 1 FDA

Purpura, Thrombocytopenic, Thrombocytopenia, Purpura, Thrombocytopenic, Idiopathic

NCT01569087 2016-12-05

Dose-finding Study of Empegfilgrastim for Neutropenia Prophylaxis in Patients With Breast Cancer

60 enrolled 17 charts

Breast Neoplasms, Neutropenia, Febrile Neutropenia

NCT02104830 2016-10-24

Study of the Efficacy and Safety of Empegfilgrastim for Neutropenia Prophylaxis in Breast Cancer Patients

135 enrolled 18 charts

Breast Neoplasms, Neutropenia, Febrile Neutropenia

NCT01809314 2016-08-19

An Observational Study of Epoetin Beta (NeoRecormon) in Participants With Cancer Receiving Chemotherapy

1,167 enrolled 8 charts

Anemia

NCT01716559 2016-08-18

An Observational Study of NeoRecormon (Epoetin Beta) in Anemic Patients With Non-myeloid Malignancy

160 enrolled 10 charts

Anemia

NCT01147809 2016-04-18

Safety and Efficacy Study for Solid Tumor Patients Treated With Eltrombopag

130 enrolled 37 charts