Clinical Trials

Anemia, Myelodysplastic Syndromes

NCT05320198 2026-03-09

Study of DISC-0974 (RALLY-MF) in Participants With Myelofibrosis or Myelodysplastic Syndrome and Anemia

Phase 1/2 Recruiting

150 enrolled

Anemia, Myelodysplastic Syndromes, Myeloproliferative Disorders, Primary Myelofibrosis

NCT06521931 2026-03-02

A Study of PN20 for the Prevention of Chemotherapy-induced Thrombocytopenia in Lymphoma or Solid Tumor Patients

Phase 1 Completed

24 enrolled

Phase 2 Not yet recruiting

Thrombocytopenia

NCT06075030 2026-02-27

A Study of AND017 in Cancer Related Anemic Patients Receiving Chemotherapy

36 enrolled

Phase 2 Not yet recruiting

Chemotherapy Induced Anemia

NCT06075043 2026-02-27

A Study of AND017 to Treat Cancer Related Anemia in Patients Not Receiving Chemotherapy

36 enrolled

Classical hematologyDermatologicLymphoidMyeloidOther hematologic neoplasm

Cancer-Related Anemia

NCT05589896 2026-02-24

A First-in-Human Study of HLA-Partially to Fully Matched Allogenic Cryopreserved Deceased Donor Bone Marrow Transplantation for Patients With Hematologic Malignancies

Phase 1/2 Recruiting

12 enrolled

Anemia, Refractory, with Excess of Blasts, Hematologic Diseases, Hodgkin Disease, Leukemia, Lymphoma, Leukemia, B-Cell, Leukemia, Biphenotypic, Acute, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Acute, Lymphoma, T-Cell, Cutaneous, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT05171049 2026-02-23

ASTER

Phase 3 Terminated

1,150 enrolled

Pulmonary Embolism, Venous Thrombosis, Venous Thromboembolism

NCT06372717 2026-02-04

A Study to Investigate APL-4098 Alone and in Combination in Adults With AML or MDS

Phase 1 Recruiting

100 enrolled

GATA2 Deficiency, Anemia, Refractory, with Excess of Blasts, Leukemia, Myeloid, Acute

NCT06456528 2026-01-12

QL0911 for the Treatment of Cancer Treatment-Induced Thrombocytopenia

Phase 2/3 Recruiting

235 enrolled

Phase EARLY_PHASE1 Recruiting

Cancer Treatment-Induced Thrombocytopenia

NCT07205315 2025-12-26

A Clinical Study Evaluating the Safety and Efficacy of GT801 Injection in Adult Patients With Relapsed/Refractory CD19-positive B-cell Hematologic Malignancies and Autoimmune Hemolytic Anemia

28 enrolled

Classical hematologyLymphoidOther hematologic neoplasm

Anemia, Hemolytic, Autoimmune, Burkitt Lymphoma, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, B-Cell

NCT05171075 2025-12-19

MAGNOLIA

Phase 3 Active not recruiting

417 enrolled

Classical hematologyGastrointestinal

Gastrointestinal Neoplasms, Pulmonary Embolism, Venous Thrombosis, Venous Thromboembolism

NCT06752850 2025-12-19

A Study to Investigate the Course of Synovial Hypertrophy in Patients With Haemophilia A on Efanesoctocog Alfa Prophylaxis

Phase 4 Active not recruiting

37 enrolled

Classical hematologyLymphoid

Hemophilia A, Lymphoma, Follicular, Synovitis

NCT06680752 2025-12-10

Clinical Study of ARD103 CAR-T Therapy for Patients With R/R AML or MDS

Phase 1/2 Recruiting

49 enrolled

Phase 3 Active not recruiting

Anemia, Refractory, with Excess of Blasts, Leukemia, Myeloid, Acute

NCT06711523 2025-11-25

Study Evaluating PEG-G-CSF Injectionin Preventing Neutropenia After Chemotherapy

250 enrolled

Classical hematologyMyeloidPlasma cell

Chemotherapy-Induced Febrile Neutropenia

NCT04582539 2025-10-22

LIMBER

Phase 1/2 Terminated

22 enrolled 28 charts

Anemia, Multiple Myeloma, Myelodysplastic Syndromes

NCT03320642 2025-10-21

GRAVITAS-119: Itacitinib in Combination With Calcineurin Inhibitor-Based Interventions for the Prophylaxis of Graft-Versus Host Disease

Phase 1 Terminated

84 enrolled

Classical hematologyLymphoidMyeloidOther hematologic neoplasm

Anemia, Refractory, with Excess of Blasts, Graft vs Host Disease, Hodgkin Disease, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Hematologic Neoplasms, Lymphoma, Mantle-Cell

NCT06220123 2025-07-22

A Study to Evaluate the Efficacy and Safety of SHR-2004 Injection in Preventing Postoperative Venous Thromboembolism in Patients Undergoing Ovarian Cancer Surgery

Classical hematologyGynecologic

225 enrolled

Preventing Postoperative Venous Thromboembolism in Patients Undergoing Ovarian Cancer Surgery

NCT04717414 2025-07-10

INDEPENDENCE

Phase 3 Active not recruiting

313 enrolled

Phase 2 Not yet recruiting

Anemia, Myeloproliferative Disorders, Primary Myelofibrosis

NCT06854276 2025-03-03

Study of SSS06 for Chemotherapy-Induced Anemia in Non-Myeloid Malignancies

80 enrolled

Chemotherapy-induced Anemia

NCT01130025 2025-02-24

Long-Term Innohep® Treatment Versus a Vitamin K Antagonist (Warfarin) for the Treatment of Venous Thromboembolism (VTE) in Cancer

900 enrolled

Venous Thromboembolism

NCT00753545 2025-02-03

Assessment of Efficacy of AZD2281 in Platinum Sensitive Relapsed Serous Ovarian Cancer

265 enrolled 25 charts 1 FDA

Classical hematologyGynecologic

Fanconi Anemia, Complementation Group D1, Ovarian Neoplasms

NCT06737081 2024-12-17

SAL-0951 in the Treatment of Chemotherapy-induced Anemia in Patients With Non-myeloid Malignancies

Phase 2 Recruiting

60 enrolled

Classical hematologyLymphoidMyeloidOther hematologic neoplasmPlasma cell

Anemia

NCT05260203 2024-11-06

MargheRITA

Phase NA Completed

124 enrolled

Treatment Adherence and Compliance, Amyloidosis, Anemia, Refractory, with Excess of Blasts, Hodgkin Disease, Multiple Myeloma, Myeloproliferative Disorders, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Acute, Lymphoma, B-Cell, Lymphoma, T-Cell, Neoplasms, Plasma Cell

NCT06616571 2024-09-27

Compare the Efficacy and Safety of QL0605 Injections at Different Timepoints

Phase 4 Recruiting

336 enrolled

BreastClassical hematology

Breast Neoplasms, Chemotherapy-Induced Febrile Neutropenia, Febrile Neutropenia

NCT01284348 2024-08-29

To Determine Safe and Effective Dose of Sotatercept for the Treatment of Chemotherapy Induced Anemia in Participants With Advanced Non-small Cell Lung Cancer

Phase 2 Terminated

26 enrolled 18 charts

Classical hematologyGenitourinaryGynecologicHead & NeckThoracic

Anemia, Urinary Bladder Neoplasms, Carcinoma, Non-Small-Cell Lung, Uterine Cervical Neoplasms, Head and Neck Neoplasms, Small Cell Lung Carcinoma

NCT03175978 2024-05-21

IGF-MTX Conjugate in the Treatment of Myelodysplastic Syndrome

Phase 1/2 Terminated

2 enrolled 14 charts

Classical hematologyMyeloidOther hematologic neoplasm

Anemia, Refractory, with Excess of Blasts, Myelodysplastic Syndromes, Leukemia, Myelomonocytic, Chronic

NCT00516373 2024-02-22

A Study to Assess the Safety and Pharmacokinetics of an Inhibitor of Poly ADP-Ribose Polymerase-1 (PARP)

Phase 1 Completed

98 enrolled

Classical hematologyGynecologic

Fanconi Anemia, Complementation Group D1, Ovarian Neoplasms

NCT00494234 2024-01-19

ICEBERG 1

BreastClassical hematology

54 enrolled 17 charts

Fanconi Anemia, Complementation Group D1, Breast Neoplasms

NCT03471078 2023-09-28

Avatrombopag for the Treatment of Chemotherapy-Induced Thrombocytopenia in Adults With Active Non-Hematological Cancers

122 enrolled 19 charts

Thrombocytopenia

NCT05261646 2023-09-28

A Clinical Study of Hetrombopag Olamine Tablets in Adults Receiving 21-day Cycles of Chemotherapy for Solid Tumours, Who Are Delayed for at Least 1 Week From Their Scheduled Cycle Because of Chemotherapy-induced Thrombocytopenia

Phase 3 Withdrawn

Classical hematologyLymphoidMyeloidOther hematologic neoplasm

Chemotherapy-Induced Thrombocytopenia

NCT03733249 2023-09-26

Long Term Follow-up Study for Patients Enrolled on the BP-004 Clinical Study

Phase 1/2 Terminated

187 enrolled 8 charts

Primary Immunodeficiency Diseases, Cytopenia, Anemia, Anemia, Aplastic, Anemia, Sickle Cell, Fanconi Anemia, Hemoglobinopathies, Leukemia, Lymphoma, Non-Hodgkin, Myelodysplastic Syndromes, Thalassemia, Leukemia, Myeloid, Acute, Hematologic Neoplasms, Anemia, Diamond-Blackfan, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT00931606 2023-09-13

MK-7962-012

Phase 2 Terminated

30 enrolled 32 charts

Anemia, Neoplasm Metastasis, Neoplasms

NCT03194542 2023-08-24

A Safety and Efficacy Study to Evaluate Luspatercept in Subjects With Myeloproliferative Neoplasm-associated Myelofibrosis Who Have Anemia With and Without Red Blood Cell-transfusion Dependence

95 enrolled 32 charts

BreastClassical hematology

Anemia, Primary Myelofibrosis

NCT03104595 2023-08-15

Management of Severe Chemotherapy-induced Neutropenia in Advanced Breast Cancer

Phase 1/2 Completed

28 enrolled

Breast Neoplasms, Febrile Neutropenia

NCT05061654 2023-08-14

CEF-10

Phase 4 Withdrawn

Hematologic Neoplasms, Febrile Neutropenia

NCT01583218 2023-08-07

APEX

7,513 enrolled 18 charts 1 FDA

Venous Thromboembolism

NCT03036813 2023-07-27

GBT_HOPE

449 enrolled 17 charts 1 FDA

Classical hematologySarcomaThoracic

Anemia, Sickle Cell

NCT02797977 2023-06-22

A Phase 1/2 Trial SRA737 in Combination With Gemcitabine and Cisplatin or Gemcitabine Alone in Advanced Cancer Subjects

Phase 1/2 Completed

153 enrolled

Fanconi Anemia, Sarcoma, Small Cell Lung Carcinoma

NCT05301517 2023-06-06

A Study to Evaluate the Efficacy and Safety of Roxadustat for the Treatment of Anemia in Participants Receiving Chemotherapy Treatment for Non-Myeloid Malignancies

159 enrolled

Classical hematologyMyeloidOther hematologic neoplasm

Chemotherapy Induced Anemia

NCT04631211 2023-05-25

Thrombosomes® in Bleeding Thrombocytopenic Patients Study

Phase 2 Terminated

21 enrolled

Anemia, Aplastic, Myelodysplastic Syndromes, Myeloproliferative Disorders, Thrombocytopenia, Hematologic Neoplasms

NCT03886831 2023-03-28

A Study of PRT543 in Participants With Advanced Solid Tumors and Hematologic Malignancies

Phase 1 Completed

232 enrolled

Classical hematologyLymphoidMyeloidOther hematologic neoplasm

Anemia, Refractory, with Excess of Blasts, Carcinoma, Adenoid Cystic, Recurrence, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Lymphoma, Large B-Cell, Diffuse, Lymphoma, Mantle-Cell, Primary Myelofibrosis

NCT05223699 2023-02-09

Study of MGTA-117 in Patients With Adult Acute Myeloid Leukemia (AML) and Myelodysplasia-Excess Blasts (MDS-EB)

Phase 1 Terminated

22 enrolled

Anemia, Refractory, with Excess of Blasts, Leukemia, Myeloid, Acute

NCT05704894 2023-01-30

Asses the Impact of Early Starting Erythropoetin in the Reduction of Transfusions Blood in Childrens

Phase 3 Unknown

320 enrolled

Anemia, Neoplasms

NCT03020160 2023-01-11

HAVEN 4

48 enrolled 44 charts 1 FDA

Classical hematologyMyeloidOther hematologic neoplasm

Hemophilia A

NCT01957176 2022-12-30

A Rollover Study to Provide Continued Treatment With Eltrombopag

Phase 4 Completed

22 enrolled 9 charts

Myelodysplastic Syndromes, Thrombocytopenia, Leukemia, Myeloid, Acute, Purpura, Thrombocytopenic, Idiopathic

NCT02847637 2022-11-16

HAVEN 3

152 enrolled 46 charts 1 FDA

Hemophilia A

NCT01736683 2022-10-24

Study of Sotatercept for the Treatment of Anemia in low-or Intermediate-1 Risk Myelodysplastic Syndromes (MDS) or Non-proliferative Chronic Myelomonocytic Leukemia (CMML)