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NCT05199584 2026-03-05

A Study Evaluating the Safety and Efficacy of ENV-101 (Taladegib) in Patients With Advanced Solid Tumors Harboring PTCH1 Loss of Function Mutations

CNSDermatologicEndocrineHead & NeckOther solid neoplasmSarcomaThoracic

Uveal Melanoma, Glioma, Adenoma, Islet Cell, Laryngeal Diseases, Medulloblastoma, Melanoma, Mesothelioma, Neuroblastoma, Pituitary Diseases, Retinoblastoma, Rhabdomyosarcoma, Sarcoma, Osteosarcoma

NCT00743353 2009-02-02

K5

Phase EARLY_PHASE1 Completed

16 enrolled

BreastCNSDermatologicHead & NeckSarcomaThoracic

Astrocytoma, Breast Neoplasms, Glioblastoma, Laryngeal Diseases, Lung Neoplasms, Melanoma, Oligodendroglioma, Sarcoma