Clinical Trials

266 enrolled 15 charts

Keratosis, Actinic

NCT02361216 2025-03-10

Efficacy and Safety of Ingenol Mebutate Gel for Actinic Keratosis Applied on Large Area on Face, Scalp or Chest

729 enrolled 14 charts

Keratosis, Actinic

NCT01449513 2025-03-07

PEP005 Gel - Biological Effects in Actinic Keratosis Assessed by Reflectance Confocal Microscopy

24 enrolled 26 charts

Keratosis, Actinic

NCT01926496 2025-03-07

Risk of Squamous Cell Carcinoma on Skin Areas Treated With Ingenol Mebutate Gel, 0.015% and Imiquimod Cream, 5%

485 enrolled 17 charts

Keratosis, Actinic

NCT01387711 2025-02-24

PEP005 Gel - Biological Effects in Actinic Keratosis Assessed by Histology

27 enrolled

Keratosis, Actinic

NCT01787383 2025-02-24

A Simultaneous Treatment Regimen Compared to a Sequential Treatment Regimen With Ingenol Mebutate Gel 0.015% and 0.05% of Two Areas With Actinic Keratosis on Face/Scalp and Trunk/Extremities

200 enrolled 16 charts

Keratosis, Actinic

NCT01803477 2025-02-24

Safety and Dose Finding Study of New Vehicle Formulations Containing Ingenol Mebutate to Treat Actinic Keratosis on the Forearm

Phase 1/2 Completed

37 enrolled

Keratosis, Actinic

NCT02124239 2025-02-24

Pharmacokinetics of Ingenol Mebutate Gel in Actinic Keratosis Under Maximum Use Conditions

79 enrolled

Keratosis, Actinic

NCT02406014 2025-02-24

Efficacy and Safety of Ingenol Mebutate Gel 0.015% Compared to Diclofenac Sodium Gel 3% in Subjects With Actinic Keratoses on the Face or Scalp

502 enrolled

Keratosis, Actinic

NCT02866695 2022-03-09

Safety and Efficacy of Ingenol Mebutate Gel 0.015% for Treatment of AK on the Face in Solid Organ Transplant Recipients

20 enrolled 12 charts

Phase EARLY_PHASE1 Withdrawn

Keratosis, Actinic

NCT01735942 2021-12-06

Ingenol Mebutate Compared to Cryotherapy for the Treatment of Skin Lesions

Keratosis, Actinic

NCT02385318 2021-11-02

To Compare Safety and Efficacy of Perrigo's Drug Product Compared to an FDA Approved Drug Product in the Treatment of Actinic Keratosis

519 enrolled 11 charts

Keratosis, Actinic

NCT02459795 2021-11-02

To Compare Safety and Efficacy of Perrigo's Drug Compared to an FDA Approved Drug in the Treatment of Actinic Keratosis

469 enrolled 10 charts

Keratosis, Actinic

NCT02654769 2020-05-12

A Study of Equivalence of Generic Ingenol Mebutate Gel 0.05% and Picato Gel 0.05% in Subjects With Actinic Keratosis

441 enrolled 9 charts

Keratosis, Actinic

NCT03200912 2020-01-14

An Equivalence Study of Generic Ingenol Mebutate Gel 0.015% and Picato Gel 0.015% in Subjects With Actinic Keratosis

507 enrolled 11 charts

Keratosis, Actinic

NCT02990221 2019-09-24

Efficacy of Ingenol Mebutate on Actinic Keratoses and Field Cancerization vs Cryotherapy

50 enrolled

Keratosis, Actinic

NCT02354391 2019-03-26

Ingenol Mebutate (Picato®) With Methyl Aminolevulinate Photodynamic Therapy for the Treatment of Actinic Keratosis

Phase 2 Unknown

20 enrolled

Keratosis, Actinic

NCT03508856 2018-04-26

Clinical and Histologic Evaluation of Picato 0.15% Gel in the Cosmetic Improvement of Photoaged Skin

Phase NA Completed

23 enrolled

Keratosis, Actinic

NCT02281682 2017-10-30

Akti

Phase 4 Unknown

624 enrolled

Keratosis, Actinic

NCT02251652 2017-04-26

Safety and Efficacy of Ingenol Mebutate 0.05% Gel When Used After Cryotherapy in the Hypertrophic Actinic Keratoses

16 enrolled 5 charts

Keratosis, Actinic

NCT00375739 2016-01-28

Study to Determine the Safety of PEP005 0.025% and 0.05% Topical Gel in Patients With Actinic Keratoses

200 enrolled

Melanosis, Keratosis, Actinic

NCT00427050 2015-09-14

A Study to Determine the Optimal Tolerated Regime and Safety of PEP005 Topical Gel

50 enrolled

Keratosis, Actinic

NCT00850681 2015-09-09

A Study to Evaluate the Photoallergic Potential of PEP005 (Ingenol Mebutate) Gel, 0.01% in Healthy Volunteers

50 enrolled

Keratosis, Actinic

NCT00850811 2015-09-09

A Study to Evaluate the Photoirritation Potential of PEP005 (Ingenol Mebutate) Gel, 0.01% in Healthy Volunteers

30 enrolled

Keratosis, Actinic

NCT00917306 2015-04-15

A Multi-center Study to Evaluate the Safety and Efficacy of PEP005 (Ingenol Mebutate) Gel, When Used to Treat Actinic Keratoses on Non-head Locations (Trunk and Extremities)

102 enrolled

Keratosis, Actinic

NCT00544297 2015-04-02

A Study to Examine the Safety and Toleration of PEP005 Topical Gel in Patients With Actinic Keratoses on the Top of the Hand

12 enrolled

Keratosis, Actinic

NCT00916006 2015-04-02

A Multi-center Study to Evaluate the Efficacy and Safety of PEP005 (Ingenol Mebutate) Gel, When Used to Treat Actinic Keratoses on the Head (Face or Scalp)

269 enrolled 9 charts

Keratosis, Actinic

NCT00107965 2015-03-25

Study to Determine the Safety of Two Applications of PEP005 Topical Gel to Actinic Keratoses

60 enrolled

Melanosis, Keratosis, Actinic

NCT00239135 2015-03-25

Study to Determine the Maximum Tolerated Dose and Safety of PEP005 Topical Gel

34 enrolled

Keratosis, Melanosis, Keratosis, Actinic

NCT00742391 2015-03-06

A Multicenter Study to Evaluate the Efficacy and Safety of PEP005 (Ingenol Mebutate) Gel When Used to Treat Actinic Keratoses (AKs) on the Non Head Locations

255 enrolled 9 charts

Keratosis, Actinic

NCT00852137 2015-03-06

A Study to Evaluate the Pharmacokinetics of PEP005 (Ingenol Mebutate) Gel, 0.05%, When Applied in a Maximal Use Setting to the Dorsal Aspect of the Forearm in Patients With Actinic Keratosis

16 enrolled 9 charts

Keratosis, Actinic

NCT00915551 2015-03-06

A Multi-Center Study to Evaluate the Efficacy and Safety of PEP005 (Ingenol Mebutate) Gel, When Used to Treat Actinic Keratoses on the Head (Face or Scalp)

278 enrolled 9 charts

Keratosis, Actinic

NCT00942604 2015-03-06

A Multicenter Study to Evaluate the Efficacy and Safety of PEP005 (Ingenol Mebutate) Gel When Used to Treat Actinic Keratoses (AKs) on the Non Head Locations

203 enrolled 8 charts

Keratosis, Actinic

NCT00544258 2015-02-12

Pharmacokinetic Study to Evaluate the Extent of Systemic Absorption of PEP005

8 enrolled

Keratosis, Actinic

NCT00108121 2015-01-19

Study to Determine the Safety of Two Applications of PEP005 Topical Gel to Nodular Basal Cell Carcinoma

60 enrolled

Carcinoma, Basal Cell

NCT02242747 2014-09-17

Safety and Tolerability Study of Ingenol Mebutate Compared to 5-FU to Treat Facial Actinic Keratosis

Phase NA Completed

100 enrolled

Keratosis, Actinic

NCT01836367 2013-12-31

Ingenol Mebutate 0.015% Gel in the Treatment of Actinic Keratoses (AK) on the Face and Scalp

20 enrolled

Facies, Keratosis, Actinic

NCT01214564 2011-01-25

Study to Evaluate the Safety and Efficacy of PEP005(Ingenol Mebutate) Gel, 0.05%, in Patients With Seborrhoeic Keratosis

24 enrolled

Keratosis, Seborrheic, Keratosis, Actinic

NCT00108134 2008-12-24

Study to Determine the Safety of Two Applications of PEP005 Topical Gel to Superficial Basal Cell Carcinoma

60 enrolled