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Interventional 1

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Other hematologic neoplasm 17 Myeloid 9 Lymphoid 6 Thoracic 3 Other solid neoplasm 3 Tumor-Agnostic 2 Plasma cell 2 Sarcoma 1 Gastrointestinal 1 Dermatologic 1 CNS 1

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pembrolizumab 303 Nivolumab 268 Ipilimumab 241 Cyclophosphamide 179 aldesleukin 137 Interleukin-2 98 fludarabine phosphate 96 trametinib 79 fludarabine 77 Temozolomide 73 Dacarbazine 73 Radiotherapy 70 dabrafenib 69 Biopsy 68 Vemurafenib 64 Imiquimod 49 Radiosurgery 48 Bevacizumab 48 Magnetic Resonance Spectroscopy 46 Blood Specimen Collection 46 sargramostim 44 Aminolevulinic Acid 44 3-ingenyl angelate 44 Specimen Handling 43 Peripheral Blood Stem Cell Transplantation 43 Cisplatin 42 Paclitaxel 41 binimetinib 40 atezolizumab 39 Carboplatin 39

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NCT01011530 2013-07-16

Dose Escalation Study of MLN4924 in Adults With Melanoma

Millennium Pharmaceuticals, Inc.

Phase 1 Completed

Melanoma

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