Clinical Trials

Carcinoma, Basal Cell

NCT05135715 2024-02-20

A Study of RC48-ADC in Advanced Melanoma Subjects With HER2 Variant (Mutation, Amplification, Overexpression)

50 enrolled

Melanoma

NCT06239623 2024-02-02

ERK Inhibitor JSI-1187 in Advanced Solid Tumors

60 enrolled

Melanoma

NCT05022901 2023-12-21

An Open-Label Expanded Access Study of the Melphalan/Hepatic Delivery System (HDS) in Patients With Hepatic Dominant Ocular Melanoma

30 enrolled

Uveal Melanoma

NCT02557321 2023-11-21

PV-10 in Combination With Pembrolizumab for Treatment of Metastatic Melanoma

50 enrolled

Melanoma

NCT05094804 2023-11-02

A Study of OR2805, a Monoclonal Antibody Targeting CD163, Alone and in Combination With Anticancer Agents

DermatologicHead & NeckSarcomaThoracic

172 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Leiomyosarcoma, Liposarcoma, Melanoma, Neoplasm Metastasis, Neoplasms

NCT04362722 2023-10-10

DUNCAN

40 enrolled

Carcinoma, Carcinoma, Basal Cell

NCT05986331 2023-09-21

Clinical Study of the Efficacy and Safety of BCD-201 and Keytruda in Subjects With Advanced Melanoma

366 enrolled

Melanoma

NCT05148325 2023-09-08

Assessment of Safety ,Tolerance and Pharmacokinetics Clinical Efficacy With BAT4706 in Advanced Solid Tumors

64 enrolled

Phase EARLY_PHASE1 Unknown

Melanoma

NCT05932511 2023-08-30

Topical Ascorbic Acid for Treatment of Squamous Cell Skin Cancer

15 enrolled

Carcinoma, Squamous Cell, Skin Neoplasms, Neoplasms, Squamous Cell

NCT05739006 2023-08-02

Clinical Trial to Evaluate the PK and Safety of BCD-201 and Keytruda® in Patients With Advanced Malignancies

131 enrolled

Carcinoma, Non-Small-Cell Lung, Melanoma

NCT05708950 2023-07-13

A Clinical Trial of KVA12123 Treatment Alone and in Combination With Pembrolizumab In Advanced Solid Tumors (VISTA-101)

BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckSarcomaThoracic

314 enrolled

Breast Neoplasms, Carcinoma, Colonic Neoplasms, Esophageal Neoplasms, Head and Neck Neoplasms, Kidney Neoplasms, Lung Neoplasms, Melanoma, Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Sarcoma, Stomach Neoplasms, Thyroid Neoplasms, Uterine Neoplasms

NCT04763083 2023-07-07

First in Human Study of NVG-111 in Relapsed/Refractory ROR1+ Malignancies

DermatologicLymphoidOther hematologic neoplasmThoracic

90 enrolled

Carcinoma, Non-Small-Cell Lung, Lymphoma, Follicular, Melanoma, Leukemia, B-Cell, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, Large B-Cell, Diffuse, Lymphoma, Mantle-Cell

NCT05451407 2023-07-07

Efficacy and Safety of TQB2618 Injection Combined With Toripalimab Injection in Patients With Advanced Melanoma

50 enrolled

Melanoma

NCT03803397 2023-07-06

Arm 1: Lysate Pulsed Dendritic Cells (PV-001-DC) in Patients With Melanoma

10 enrolled

Melanoma

NCT05223218 2023-07-03

Investigating the Diagnostic Potential of Tear Proteins in Cancer - A Pilot Study

BreastDermatologicGastrointestinalGenitourinaryGynecologic

500 enrolled

Breast Neoplasms, Melanoma, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms

NCT05263453 2023-05-31

HL-085+Vemurafenib to Treat Advanced Melanoma Patients With BRAF V600E/K Mutation

104 enrolled

Melanoma

NCT05823246 2023-05-26

Safety and Efficacy Study of QLF31907 in Advanced Melanoma and Urothelial Carcinoma

DermatologicGenitourinary

66 enrolled

Carcinoma, Transitional Cell, Melanoma

NCT05539157 2023-04-04

Study to Evaluate JCXH-211 as Monotherapy in Patients With Malignant Solid Tumors

1 enrolled

Neoplasms, Skin Neoplasms

NCT03132675 2023-03-27

Keynote-695

143 enrolled

Melanoma

NCT05783882 2023-03-24

FLAT

114 enrolled

Melanoma

NCT05727839 2023-03-20

Study to Evaluate JCXH-211 as Monotherapy in Patients With Malignant Solid Tumors

156 enrolled

Neoplasms, Skin Neoplasms

NCT03787602 2023-03-02

Navtemadlin (KRT-232) With or Without Anti-PD-1/Anti-PD-L1 for the Treatment of Patients With Merkel Cell Carcinoma

115 enrolled

Carcinoma, Merkel Cell

NCT03913923 2023-02-10

OBERTON

117 enrolled

Melanoma

NCT03775525 2022-12-23

GEN602

BreastDermatologicGastrointestinalHead & NeckLymphoidSarcoma

127 enrolled

Squamous Cell Carcinoma of Head and Neck, Breast Neoplasms, Carcinoma, Basal Cell, Colonic Neoplasms, Lymphoma, Pancreatic Neoplasms, Sarcoma, Stomach Neoplasms, Lymphoma, T-Cell, Cutaneous

NCT05647954 2022-12-13

A Study of HX008 Plus Transcatheter Arterial Chemoembolization (TACE) in the First-Line Treatment of Subjects With Stage IV (M1c) Melanoma That is Metastatic to the Liver

350 enrolled

DermatologicEndocrineNET

Melanoma Neuroendocrine Tumors Neuroectodermal Tumors Neoplasms Germ Cell and Embryonal Neoplasms by Histologic Type Neoplasms Neoplasms

NCT00986661 2022-11-02

A Study to Assess PV-10 Chemoablation of Cancer of the Liver

BreastDermatologicEndocrineGastrointestinalThoracic

78 enrolled

Uveal Melanoma, Breast Neoplasms, Carcinoid Tumor, Colonic Neoplasms, Carcinoma, Hepatocellular, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Pancreatic Neoplasms, Colorectal Neoplasms

NCT04118868 2022-10-12

Pembrolizumab Administered Via the Sofusa® DoseConnect™ in Patients With Relapsed/Refractory Cutaneous T-cell Lymphoma.

10 enrolled

DermatologicLymphoid

Mycosis Fungoides, Lymphoma, T-Cell, Cutaneous

NCT05569057 2022-10-07

A Phase I Trial of SIM1811-03 in Subjects With Advanced Solid Tumors and Cutaneous T-cell Lymphoma

100 enrolled

DermatologicLymphoid

Lymphoma, T-Cell, Cutaneous

NCT03634982 2022-09-01

Dose Escalation of RMC-4630 Monotherapy in Relapsed/Refractory Solid Tumors

DermatologicGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

133 enrolled

Urinary Bladder Neoplasms, Bronchial Neoplasms, Carcinoma, Bronchogenic, Carcinoma, Non-Small-Cell Lung, Carcinoma, Squamous Cell, Uterine Cervical Neoplasms, Digestive System Diseases, Digestive System Neoplasms, Esophageal Diseases, Esophageal Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Head and Neck Neoplasms, Lung Diseases, Lung Neoplasms, Melanoma, Neoplasms, Neoplasms by Site, Neoplasms, Glandular and Epithelial, Noonan Syndrome, Ovarian Neoplasms, Respiratory Tract Diseases, Respiratory Tract Neoplasms, Skin Neoplasms, Thoracic Neoplasms, Uterine Neoplasms, Neoplasms, Squamous Cell

NCT03385486 2022-05-03

Study of TBX-3400 in Patients With Stage III and IV Melanoma Resistant or Refractory to Immune Checkpoint Inhibitors

72 enrolled

Melanoma

NCT02076646 2022-04-14

A Phase I/II Dose Escalation Study of the Tumor-targeting Human L19-IL2 Monoclonal Antibody-cytokine Fusion Protein in Combination With Dacarbazine for Patients With Metastatic Melanoma

96 enrolled

Melanoma, Neoplasm Metastasis

NCT02637531 2022-04-04

A Dose-Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of IPI-549

BreastDermatologicEndocrineOther solid neoplasmThoracic

219 enrolled

Carcinoma, Non-Small-Cell Lung, Melanoma, Mesothelioma, Adrenocortical Carcinoma, Triple Negative Breast Neoplasms

NCT05230186 2022-02-09

A Tissue Collection Study in Patients Who Respond to Immune Checkpoint Inhibitors to Identify Targets of Tumor-Reactive T Cells.

BreastDermatologicGastrointestinalGenitourinaryGynecologicThoracic

200 enrolled

Urinary Bladder Neoplasms, Carcinoma, Renal Cell, Colonic Neoplasms, Lung Neoplasms, Melanoma, Endometrial Neoplasms, Triple Negative Breast Neoplasms

NCT05164393 2022-01-27

COAKS

60 enrolled

Keratosis, Actinic

NCT05190185 2022-01-13

A Clinical Trial of TAA06 Injection in Advanced Solid Tumors

DermatologicGastrointestinalThoracic

18 enrolled

Lung Neoplasms, Melanoma, Colorectal Neoplasms

NCT05152407 2021-12-30

MRB 0.3% Serum Effectiveness on 2 Early Clinical Markers of Photoinduced Cutaneous Aging: Actinic Lentigo and Actinic Keratosis

Phase NA Unknown

35 enrolled

Keratosis, Actinic

NCT05103891 2021-12-01

Relative Bioavailability of Binimetinib 3 x 15 mg and 45 mg Formulations

14 enrolled

Melanoma

NCT05117138 2021-11-11

Safety and Efficacy of Chimeric Antigen Receptor T Lymphocytes for Patients With Intermediate and Advanced Tumors

DermatologicHead & NeckThoracic

39 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Melanoma

NCT03291002 2021-11-04

Study of Intratumoral CV8102 in cMEL, cSCC, hnSCC, and ACC

98 enrolled

DermatologicHead & Neck

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Adenoid Cystic, Melanoma

NCT04521075 2021-08-16

A Phase Ib Trial to Evaluate the Safety and Efficacy of FMT and Nivolumab in Subjects With Metastatic or Inoperable Melanoma, MSI-H, dMMR or NSCLC

42 enrolled

Carcinoma, Non-Small-Cell Lung, Melanoma

NCT04860076 2021-04-26

Open-label, Uncontrolled, Non-Interventional, Retrospective Study to Evaluate Molecular Determinants of Outcome to the Immune Checkpoint Inhibitors (Anti-PD-1/Anti-PD-L1 Monoclonal Antibodies) Treatment for Solid Tumors

400 enrolled

Lung Neoplasms, Melanoma

NCT04756934 2021-02-16

A Study of HX008 Plus LP002 for the Treatment of Patients With Advanced Melanoma

63 enrolled

Melanoma

NCT04749485 2021-02-11

A Study of HX008 for the Treatment of Patients With Malignant Melanoma

119 enrolled

Melanoma

NCT03896958 2020-12-04

PIONEER

BreastCNSDermatologicEndocrineGastrointestinalGenitourinaryGynecologicHead & NeckSarcomaThoracic

1,000 enrolled

Adenocarcinoma of Lung, Adrenal Gland Neoplasms, Anus Neoplasms, Bile Duct Neoplasms, Urinary Bladder Neoplasms, Brain Neoplasms, Breast Neoplasms, Adenocarcinoma, Bronchiolo-Alveolar, Carcinoma, Renal Cell, Carcinoma, Squamous Cell, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Glioblastoma, Head and Neck Neoplasms, Carcinoma, Hepatocellular, Kidney Neoplasms, Laryngeal Neoplasms, Liver Neoplasms, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Neoplasms, Neoplasms, Unknown Primary, Neurologic Manifestations, Oligodendroglioma, Pancreatic Neoplasms, Prostatic Neoplasms, Rectal Neoplasms, Sarcoma, Skin Neoplasms, Stomach Neoplasms, Testicular Neoplasms, Uterine Neoplasms, Vulvar Neoplasms, Cholangiocarcinoma, Small Cell Lung Carcinoma, Thyroid Carcinoma, Anaplastic

NCT03269565 2020-09-18

MIRACULUM

126 enrolled

Melanoma

NCT04136470 2020-08-10

BioForte Technology for in Silico Identification of Candidates for a New Microbiome-based Therapeutics and Diagnostics

130 enrolled

Carcinoma, Non-Small-Cell Lung, Melanoma, Neoplasms

NCT03734913 2020-07-22

A Phase 1 Study of ZSP1602 in Participants With Advanced Solid Tumors

CNSDermatologicEndocrineNETThoracic

65 enrolled

Carcinoma, Basal Cell, Glioblastoma, Medulloblastoma, Neuroendocrine Tumors, Small Cell Lung Carcinoma

NCT03544723 2020-06-09

Safety and Efficacy of p53 Gene Therapy Combined With Immune Checkpoint Inhibitors in Solid Tumors.