Clinical Trials Browser

ACTH Syndrome, Ectopic × Endocrine × Clear all

ACTH Syndrome, Ectopic, Adrenal Gland Neoplasms, Bone Diseases, Metabolic, Cardiovascular Diseases, Hyperaldosteronism, Hyperinsulinism, Hypertension

NCT03604198 2026-02-19

Extension Study to Evaluate the Safety of Long-Term Use of Relacorilant in Patients With Cushing Syndrome

Phase 2 Active not recruiting

125 enrolled

Endocrine

ACTH Syndrome, Ectopic, Adrenal Cortex Neoplasms, Cushing Syndrome, Diabetes Mellitus, Type 2, Hypertension, Adrenocortical Carcinoma, Pituitary ACTH Hypersecretion

NCT05307328 2025-10-08

RESCUE

Phase 2 Completed

26 enrolled

Endocrine

ACTH Syndrome, Ectopic, Cushing Syndrome, Pituitary ACTH Hypersecretion

NCT03697109 2025-07-16

GRACE

Phase 3 Completed

152 enrolled 28 charts

Endocrine

ACTH Syndrome, Ectopic, Cushing Syndrome, Diabetes Mellitus, Type 2, Hypertension, Pituitary ACTH Hypersecretion

NCT05804669 2025-04-10

A Study to Evaluate the Safety and PK of CRN04894 for the Treatment of Cushing's Syndrome

Phase 1/2 Recruiting

18 enrolled

Endocrine

ACTH Syndrome, Ectopic, Cushing Syndrome, Pituitary ACTH Hypersecretion

NCT06576336 2024-08-28

3DAdrenal

Phase 4 Completed

350 enrolled

Endocrine

ACTH Syndrome, Ectopic, Adrenal Gland Neoplasms

NCT05446779 2024-04-16

SuddenDeath

Active not recruiting

400 enrolled

Endocrine

ACTH Syndrome, Ectopic, Endocrine Gland Neoplasms, Hyperaldosteronism, Pheochromocytoma

NCT04373265 2024-02-23

Study of Relacorilant in Combination With Pembrolizumab for Patients With Adrenocortical Carcinoma Which Produces Too Much Stress Hormone (Cortisol)

Phase 1 Completed

15 enrolled

Endocrine

ACTH Syndrome, Ectopic, Adrenal Cortex Neoplasms, Adrenal Gland Diseases, Adrenocortical Hyperfunction, Cushing Syndrome, Diabetes Mellitus, Type 2, Endocrine System Diseases, Hyperglycemia, Hypertension, Pathologic Processes, Glucose Intolerance, Adrenocortical Carcinoma

NCT05361083 2022-05-04

First-in-human Evaluation of [18F]CETO

Phase EARLY_PHASE1 Completed

20 enrolled

Endocrine

ACTH Syndrome, Ectopic, Adrenocortical Carcinoma

NCT04890444 2022-02-14

CASE

Recruiting

2,000 enrolled

Endocrine

Adrenal incidentaloma, ACTH Syndrome, Ectopic, Adrenal Cortex Neoplasms, Adrenal Insufficiency, Adrenal Hyperplasia, Congenital, Cushing Syndrome, Hyperaldosteronism, Pheochromocytoma

NCT04433819 2020-06-16

Nailfold Capillaroscopy Evaluation in Cushing Syndrome Patients

Unknown

200 enrolled

Endocrine

ACTH Syndrome, Ectopic, Cushing Syndrome, Pituitary ACTH Hypersecretion

NCT03474237 2020-03-18

A Prospective Cohort Study for Patients With Adrenal Diseases

Enrolling by invitation

1,500 enrolled

Endocrine

Adrenal incidentaloma, ACTH Syndrome, Ectopic, Cushing Syndrome, Hyperaldosteronism, Pheochromocytoma, Adrenocortical Carcinoma

NCT02804750 2019-10-15

Study to Evaluate CORT125134 in Participants With Cushing's Syndrome

Phase 2 Completed

35 enrolled 13 charts

Endocrine

ACTH Syndrome, Ectopic, Adrenal Cortex Neoplasms, Cushing Syndrome, Diabetes Mellitus, Type 2, Hypertension, Adrenocortical Carcinoma, Pituitary ACTH Hypersecretion

NCT03830593 2019-10-10

Laparoscopic Adrenalectomy for Large Adrenal Tumors.

Completed

102 enrolled

Endocrine

ACTH Syndrome, Ectopic, Adrenal Gland Neoplasms

NCT00958841 2016-07-26

Study of Pasireotide in Patients With Rare Tumors of Neuroendocrine Origin

Phase 2 Terminated

118 enrolled 11 charts

EndocrineGastrointestinal

ACTH Syndrome, Ectopic, Nelson Syndrome, Pancreatic Neoplasms, Pituitary Neoplasms, Neuroectodermal Tumors, Primitive

NCT00796783 2014-06-20

A Study to Confirm Recurrent or Persistent Cushing's Syndrome in Patients With Signs or Symptoms of Hypercortisolemia

Terminated

2 enrolled

Endocrine

ACTH Syndrome, Ectopic, Adrenal Cortex Neoplasms, Choristoma, Cushing Syndrome, Hirsutism, Pituitary Diseases, Pituitary ACTH Hypersecretion

NCT00936741 2014-04-02

An Extension Study of CORLUX in the Treatment of Endogenous Cushing's Syndrome

Phase 3 Completed

30 enrolled 8 charts

Endocrine

ACTH Syndrome, Ectopic, Adrenal Cortex Neoplasms, Choristoma, Cushing Syndrome, Hirsutism, Pituitary Diseases, Pituitary ACTH Hypersecretion

NCT01371565 2014-03-18

Compassionate Use of CORLUX® (Mifepristone) in the Treatment of Signs and Symptoms of Endogenous Cushing's Syndrome

Phase 3 Completed

4 enrolled 7 charts

Endocrine

ACTH Syndrome, Ectopic, Cushing Syndrome, Pituitary Diseases, Pituitary ACTH Hypersecretion

NCT00569582 2013-08-22

SEISMIC

Phase 3 Completed

50 enrolled 8 charts

Endocrine

ACTH Syndrome, Ectopic, Adrenal Cortex Neoplasms, Choristoma, Cushing Syndrome, Hirsutism, Pituitary Diseases, Pituitary ACTH Hypersecretion

Clinical Trials

Clinical and Molecular Characteristics of Primary Aldosteronism in Blacks

Extension Study to Evaluate the Safety of Long-Term Use of Relacorilant in Patients With Cushing Syndrome

RESCUE

GRACE

A Study to Evaluate the Safety and PK of CRN04894 for the Treatment of Cushing's Syndrome

3DAdrenal

SuddenDeath

Study of Relacorilant in Combination With Pembrolizumab for Patients With Adrenocortical Carcinoma Which Produces Too Much Stress Hormone (Cortisol)

First-in-human Evaluation of [18F]CETO

CASE

Nailfold Capillaroscopy Evaluation in Cushing Syndrome Patients

A Prospective Cohort Study for Patients With Adrenal Diseases

Study to Evaluate CORT125134 in Participants With Cushing's Syndrome

Laparoscopic Adrenalectomy for Large Adrenal Tumors.

Study of Pasireotide in Patients With Rare Tumors of Neuroendocrine Origin

A Study to Confirm Recurrent or Persistent Cushing's Syndrome in Patients With Signs or Symptoms of Hypercortisolemia

An Extension Study of CORLUX in the Treatment of Endogenous Cushing's Syndrome

Compassionate Use of CORLUX® (Mifepristone) in the Treatment of Signs and Symptoms of Endogenous Cushing's Syndrome

SEISMIC