Clinical Trials

Neuroblastoma, Pheochromocytoma

NCT05199584 2026-03-05

A Study Evaluating the Safety and Efficacy of ENV-101 (Taladegib) in Patients With Advanced Solid Tumors Harboring PTCH1 Loss of Function Mutations

CNSDermatologicEndocrineHead & NeckOther solid neoplasmSarcomaThoracic

20 enrolled

Uveal Melanoma, Glioma, Adenoma, Islet Cell, Laryngeal Diseases, Medulloblastoma, Melanoma, Mesothelioma, Neuroblastoma, Pituitary Diseases, Retinoblastoma, Rhabdomyosarcoma, Sarcoma, Osteosarcoma

NCT04706910 2026-02-09

18F-DOPA II - PET Imaging Optimization

Phase 3 Recruiting

800 enrolled

Phase 1/2 Active not recruiting

Brain Neoplasms, Neuroblastoma, Parkinson Disease, Neuroendocrine Tumors, Lewy Body Disease, Congenital Hyperinsulinism

NCT02650401 2025-12-24

STARTRK-NG

69 enrolled 1 FDA

CNSEndocrineGenitourinaryHead & NeckSarcoma

Thyroid Cancer, Papillary, Brain Neoplasms, Glioma, Medulloblastoma, Neoplasm Metastasis, Wilms Tumor, Neuroblastoma, Recurrence, Salivary Gland Neoplasms, Sarcoma, Sarcoma, Ewing, Central Nervous System Neoplasms, Nephroma, Mesoblastic

NCT01850888 2025-12-18

MIBG for Refractory Neuroblastoma and Pheochromocytoma

Phase NA Completed

15 enrolled

Phase 2 Active not recruiting

Neuroblastoma, Pheochromocytoma

NCT04284774 2025-12-04

Tipifarnib for the Treatment of Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders With HRAS Gene Alterations, a Pediatric MATCH Treatment Trial

5 enrolled 9 charts

CNSDermatologicEndocrineGastrointestinalGenitourinaryHead & NeckLymphoidMyeloidSarcoma

Ependymoma, Glioma, Histiocytosis, Langerhans-Cell, Lymphoma, Non-Hodgkin, Medulloblastoma, Melanoma, Wilms Tumor, Neuroblastoma, Pheochromocytoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Thyroid Neoplasms, Hepatoblastoma, Neuroectodermal Tumors, Primitive, Peripheral, Rhabdoid Tumor

NCT03541720 2025-12-03

18F-Fluorodopamine PET Studies of Neuroblastoma and Pheochromocytoma

Phase EARLY_PHASE1 Active not recruiting

13 enrolled

Neuroblastoma, Pheochromocytoma

NCT06041516 2025-07-11

Antibody Drug Conjugate ADCT-701 in Neuroendocrine Tumors and Carcinomas

Phase 1 Recruiting

70 enrolled

Phase 2 Active not recruiting

Neuroblastoma, Paraganglioma, Pheochromocytoma, Adrenocortical Carcinoma, Carcinoma, Neuroendocrine, Neuroendocrine Tumors

NCT06638931 2025-05-28

ANTARES

28 enrolled

BreastCNSEndocrineGastrointestinalGenitourinaryGynecologicHead & NeckNETOther solid neoplasmSarcomaThoracic

Urachal adenocarcinoma, Urachal cancer, Fibrolamellar hepatocellular carcinoma, Secretory breast carcinoma, Carcinoma, Ovarian Epithelial, Adrenal Gland Neoplasms, Anus Neoplasms, Biliary Tract Neoplasms, Carcinosarcoma, Carcinoma, Adenoid Cystic, Fallopian Tube Neoplasms, Fibrosarcoma, Gallbladder Neoplasms, Granulosa Cell Tumor, Hemangiosarcoma, Leiomyosarcoma, Mesothelioma, Neuroblastoma, Parathyroid Neoplasms, Penile Neoplasms, Sarcoma, Sarcoma, Kaposi, Osteosarcoma, Thyroid Neoplasms, Trophoblastic Neoplasms, Urethral Neoplasms, Vaginal Neoplasms, Vulvar Neoplasms, Hepatoblastoma, Endodermal Sinus Tumor, Neuroectodermal Tumors, Primitive, Cholangiocarcinoma, Sertoli-Leydig Cell Tumor, Neurofibrosarcoma, Hemangioblastoma, Neuroendocrine Tumors

NCT06233903 2025-01-21

18F-mFBG Expression in Neural Crest Tumors and Organs Innervated by the Sympathetic Nervous System

Phase 2 Withdrawn

Phase EARLY_PHASE1 Recruiting

Neuroblastoma, Paraganglioma, Pheochromocytoma

NCT05069220 2024-03-01

18F-MFBG PET/CT in the Evaluation of Neural Crest Tumor

150 enrolled

Neuroblastoma, Paraganglioma, Pheochromocytoma, Neuroendocrine Tumors

NCT03273712 2023-02-09

Dosimetry-Guided, Peptide Receptor Radiotherapy (PRRT) With 90Y-DOTA- tyr3-Octreotide (90Y-DOTATOC)

39 enrolled 9 charts

Medulloblastoma, Meningioma, Neuroblastoma, Neuroendocrine Tumors

NCT03042416 2022-01-10

18F-DOPA PET Imaging: an Evaluation of Biodistribution and Safety

Phase 3 Completed

400 enrolled

Neuroblastoma, Parkinson Disease, Neuroendocrine Tumors, Congenital Hyperinsulinism

NCT01869725 2021-09-22

Comparative Study of Sensitivity of Ga-DOTATOC PET vs Octreoscan SPECT + CT

68 enrolled 8 charts

Medulloblastoma, Neuroblastoma, Somatostatinoma, Neuroendocrine Tumors

NCT02441062 2020-12-21

Impact of Ga-68 DOTATOC PET-CT Imaging in Management of Neuroendocrine Tumors

122 enrolled 6 charts

Carcinoid Tumor, Medulloblastoma, Neuroblastoma, Neuroendocrine Tumors

NCT02177773 2019-11-12

DOTA-TOC

Phase 1/2 Terminated

300 enrolled 5 charts

Carcinoid Tumor, Neuroblastoma, Paraganglioma, Neuroendocrine Tumors

NCT00126412 2019-05-31

Meta-Iodobenzylguanidine (123I mIBG) Scintigraphy in Patients Being Evaluated for Phaeochromocytoma or Neuroblastoma

Phase 3 Completed

251 enrolled

Disease, Neuroblastoma, Pheochromocytoma

NCT00947167 2017-03-03

A Phase II Study of Pertuzumab and Erlotinib for Metastatic or Unresectable Neuroendocrine Tumors

Phase 2 Terminated

4 enrolled 5 charts

Adrenal Gland Neoplasms, Carcinoid Tumor, Multiple Endocrine Neoplasia, Neuroblastoma, Neuroendocrine Tumors

NCT00049023 2016-06-21

Radiolabeled Octreotide in Treating Children With Advanced or Refractory Solid Tumors

27 enrolled

CNSEndocrineSarcoma

Familial ependymoma, Insulinoma, Adenoma, Islet Cell, Medulloblastoma, Neuroblastoma, Pheochromocytoma, Sarcoma, Gastrinoma, Central Nervous System Neoplasms, Neuroectodermal Tumors, Primitive, Peripheral, Carcinoma, Islet Cell

NCT01048086 2016-06-21

90Y DOTA/Retinoic Acid for Neuroblastoma and Neuroendocrine Tumor (NET)

Phase 2 Withdrawn

Neuroblastoma, Neuroendocrine Tumors

NCT00831844 2015-03-30

Cixutumumab in Treating Patients With Relapsed or Refractory Solid Tumors

CNSEndocrineGastrointestinalGenitourinaryOther solid neoplasmSarcoma

116 enrolled 8 charts

Wilms Tumor, Neuroblastoma, Retinoblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Sarcoma, Synovial, Neuroectodermal Tumors, Hepatoblastoma, Adrenocortical Carcinoma

NCT01048892 2014-01-30

Seneca Valley Virus-001 and Cyclophosphamide in Treating Young Patients With Relapsed or Refractory Neuroblastoma, Rhabdomyosarcoma, or Rare Tumors With Neuroendocrine Features

CNSEndocrineGenitourinaryOther solid neoplasmSarcoma

22 enrolled

Kidney Neoplasms, Wilms Tumor, Neuroblastoma, Retinoblastoma, Sarcoma, Adrenocortical Carcinoma

NCT00091182 2013-06-05

Oxaliplatin in Treating Young Patients With Recurrent Solid Tumors That Have Not Responded to Previous Treatment

CNSEndocrineGastrointestinalGenitourinaryGynecologicHead & NeckSarcoma

180 enrolled

Familial ependymoma, Ovarian Germ Cell Cancer, Astrocytoma, Carcinoma, Renal Cell, Colonic Neoplasms, Nasopharyngeal Neoplasms, Neuroblastoma, Rectal Neoplasms, Osteosarcoma, Teratoma, Testicular Neoplasms, Hepatoblastoma, Neuroectodermal Tumors, Primitive, Peripheral, Adrenocortical Carcinoma, Optic Nerve Glioma

NCT00436657 2012-04-02

Continuous Hyperthermic Peritoneal Perfusion (CHPP) With Cisplatin for Children With Peritoneal Cancer

CNSEndocrineGastrointestinalGenitourinaryGynecologicSarcoma

10 enrolled

Adenocarcinoma, Gastrointestinal Neoplasms, Neoplasms, Wilms Tumor, Neuroblastoma, Ovarian Neoplasms, Peritoneal Neoplasms, Retroperitoneal Neoplasms, Rhabdomyosarcoma, Sarcoma, Adrenocortical Carcinoma, Desmoplastic Small Round Cell Tumor

NCT01373736 2011-06-15

123I-MIBG Scintigraphy in Patients Being Evaluated for Neuroendocrine Tumors

Phase 3 Unknown

Carcinoid Tumor, Neuroblastoma, Paraganglioma, Pheochromocytoma, Carcinoma, Medullary

NCT00005860 2011-04-26

Oxaliplatin With Or Without Floxuridine and Leucovorin in Treating Patients With Metastatic Cancer of the Peritoneum