Clinical Trials

Neuroendocrine Tumors

NCT04505553 2026-01-21

Oral Cryotherapy Plus Acupressure and Acupuncture Versus Oral Cryotherapy for Decreasing Chemotherapy-Induced Peripheral Neuropathy From Oxaliplatin-Based Chemotherapy in Patients With Gastrointestinal Cancer

78 enrolled 14 charts

Gastro-enteropancreatic neuroendocrine tumor, Anus Neoplasms, Appendiceal Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Gastrointestinal Neoplasms, Carcinoma, Hepatocellular, Adenoma, Islet Cell, Pancreatic Neoplasms, Rectal Neoplasms, Stomach Neoplasms

NCT00410761 2025-09-24

An Efficacy Study Comparing ZD6474 to Placebo in Medullary Thyroid Cancer

331 enrolled 15 charts

Familial medullary thyroid carcinoma, Thyroid Neoplasms, Carcinoma, Medullary

NCT04702737 2025-09-12

DeLLpro-300

Phase 1 Completed

41 enrolled 19 charts

EndocrineGenitourinary

Neuroendocrine Prostate Cancer

NCT04462471 2025-09-08

Vemurafenib Plus Copanlisib in Radioiodine-Refractory (RAIR) Thyroid Cancers

Phase 1 Completed

8 enrolled 8 charts

Thyroid cancer, follicular, Thyroid Cancer, Papillary, Thyroid Neoplasms

NCT02973997 2025-08-29

Lenvatinib and Pembrolizumab in Differentiated Thyroid Cancers (DTC)

57 enrolled 14 charts

Thyroid cancer, Hurthle cell, Thyroid Cancer, Papillary, Adenocarcinoma, Follicular

NCT01471639 2025-08-15

Sprix

37 enrolled 7 charts

Emergencies, Multiple Endocrine Neoplasia Type 1

NCT03697109 2025-07-16

GRACE

152 enrolled 28 charts

ACTH Syndrome, Ectopic, Cushing Syndrome, Diabetes Mellitus, Type 2, Hypertension, Pituitary ACTH Hypersecretion

NCT04400474 2025-06-19

CABATEN

CNSEndocrineHead & NeckNET

93 enrolled 17 charts

Adenocarcinoma, Paraganglioma, Pheochromocytoma, Neuroendocrine Tumors, Thyroid Carcinoma, Anaplastic

NCT04552769 2025-06-05

Abemaciclib in Metastatic or Locally Advanced Anaplastic/Undifferentiated Thyroid Cancer

9 enrolled 10 charts

Thyroid Neoplasms, Thyroid Carcinoma, Anaplastic

NCT03037385 2025-05-31

ARROW

590 enrolled 58 charts 5 FDA

EndocrineGastrointestinalHead & NeckNETThoracic

Thyroid Cancer, Papillary, Adenocarcinoma, Adenocarcinoma, Papillary, Bronchial Neoplasms, Carcinoma, Carcinoma, Bronchogenic, Carcinoma, Non-Small-Cell Lung, Colonic Diseases, Colonic Neoplasms, Digestive System Diseases, Digestive System Neoplasms, Endocrine System Diseases, Endocrine Gland Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Head and Neck Neoplasms, Intestinal Diseases, Intestinal Neoplasms, Lung Diseases, Lung Neoplasms, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Glandular and Epithelial, Neoplasms, Nerve Tissue, Respiratory Tract Diseases, Respiratory Tract Neoplasms, Thoracic Neoplasms, Thyroid Diseases, Thyroid Neoplasms, Colorectal Neoplasms, Neuroectodermal Tumors, Carcinoma, Medullary, Carcinoma, Neuroendocrine, Neuroendocrine Tumors, Multiple Endocrine Neoplasia Type 2a

NCT04129411 2025-05-20

Treatment of Papillary Thyroid Carcinoma With Radiofrequency Ablation

5 enrolled 7 charts

Papillary Thyroid Microcarcinoma, Thyroid Cancer, Papillary, Thyroid Neoplasms

NCT02246127 2025-05-11

SEQTOR

141 enrolled 27 charts

Neuroendocrine Tumors

NCT03289741 2025-05-09

A Study to Evaluate Patient Experience in the Therapy of Neuroendocrine Tumors Treated With Octreotide Long Acting Release Versus Lanreotide

51 enrolled 10 charts

Neuroendocrine Tumors

NCT00113360 2025-05-01

RAD001 Plus Octreotide Depot in Metastatic or Unresectable Low Grade Neuroendocrine Carcinoma

67 enrolled 6 charts

Carcinoma, Islet Cell, Carcinoma, Neuroendocrine

NCT06456723 2025-05-01

FETONET

56 enrolled 9 charts

Neuroendocrine Tumors

NCT04772469 2025-04-29

Self-Test Strategies and Linkage Incentives to Improve ART and PrEP Uptake in Men

934 enrolled 13 charts

Acquired Immunodeficiency Syndrome, Retroviridae Infections, RNA Virus Infections, Virus Diseases, Sexually Transmitted Diseases, Viral, HIV Infections, Multiple Endocrine Neoplasia Type 1

NCT02487095 2025-04-13

Trial of Topotecan With VX-970 (M6620), an ATR Kinase Inhibitor, in Small Cell Cancers and Extrapulmonary Small Cell Cancers

EndocrineGynecologicThoracic

62 enrolled 29 charts

Carcinoma, Non-Small-Cell Lung, Uterine Cervical Neoplasms, Ovarian Neoplasms, Carcinoma, Neuroendocrine, Small Cell Lung Carcinoma

NCT00381641 2025-03-28

Sunitinib Malate in Treating Patients With Thyroid Cancer That Did Not Respond to Iodine I 131 and Cannot Be Removed by Surgery

63 enrolled 12 charts

Thyroid Cancer, Papillary, Thyroid Neoplasms, Adenocarcinoma, Follicular, Carcinoma, Medullary

NCT04986085 2025-03-28

NUTRIGETNE

Completed

399 enrolled 17 charts

Gastro-enteropancreatic neuroendocrine tumor, Neuroendocrine Tumors

NCT02489903 2025-03-17

RRx-001 in Lung Cancer, Ovarian Cancer and Neuroendocrine Tumors Prior to Re-administration of Platinum Based Doublet Regimens (QUADRUPLE THREAT)

EndocrineGynecologicNETThoracic

139 enrolled 14 charts

Carcinoma, Ovarian Epithelial, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Carcinoma, Small Cell, Neuroendocrine Tumors

NCT04032106 2025-03-14

HPV Vaccine Intervention for Young Sexual Minority Men

1,227 enrolled 8 charts

Multiple Endocrine Neoplasia Type 1

NCT02795858 2025-02-19

A Phase II Study of Ramucirumab With Somatostatin Analog Therapy in Patients With Advanced, Progressive Carcinoid Tumors

43 enrolled 11 charts

Carcinoid Tumor

NCT02437318 2025-02-13

SOLAR-1

572 enrolled 22 charts 1 FDA

BreastEndocrine

Breast Neoplasms, Neoplasms, Multiple Endocrine Neoplasia Type 1

NCT02842749 2025-02-10

Phase IV Study of the Safety and Efficacy of Everolimus in Adult Patients With Progressive pNET in China

61 enrolled 9 charts

Pancreatic Neuroendocrine Tumors

NCT05680675 2025-02-06

Dual-Tracer Theranostic PET

EndocrineGenitourinaryNET

50 enrolled 8 charts

Prostatic Neoplasms, Neuroendocrine Tumors

NCT04524442 2025-01-24

Post-Authorization Safety Study (PASS) of LysaKare® in Adult Gastroenteropancreatic Neuroendocrine Tumor (GEP-NET) Patients

42 enrolled 11 charts

Gastro-enteropancreatic neuroendocrine tumor, Carcinoid Tumor, Neuroendocrine Tumors

NCT03980925 2025-01-13

Platinum-doublet Chemotherapy and Nivolumab for the Treatment of Subjects With Neuroendocrine Neoplasms (NENs) of the Gastroenteropancreatic (GEP) Tract or of Unknown (UK) Origin.

37 enrolled 25 charts

Gastro-enteropancreatic neuroendocrine tumor, Neuroendocrine Tumors

NCT03095274 2025-01-09

DUNE

126 enrolled 18 charts

Neuroendocrine Tumors

NCT03034200 2024-11-26

Phase 2 Study of ONC201 in Neuroendocrine Tumors

30 enrolled 12 charts

Neuroendocrine Tumors

NCT03070301 2024-10-10

A Study of LEE011 With Everolimus in Patients With Advanced Neuroendocrine Tumors

21 enrolled 8 charts

Neuroendocrine Tumors

NCT01794793 2024-10-01

Study to Allow Access to Pasireotide for Patients Benefiting From Pasireotide Treatment in Novartis-sponsored Studies

DermatologicEndocrineGenitourinaryNET

337 enrolled 8 charts

Acromegaly, Dumping Syndrome, Melanoma, Neoplasms, Pituitary Neoplasms, Prostatic Neoplasms, Neuroendocrine Tumors, Pituitary ACTH Hypersecretion

NCT01678664 2024-09-25

EVACEL

74 enrolled 10 charts

Neoplasm Metastasis, Neoplasms, Neuroendocrine Tumors

NCT02393690 2024-07-26

Iodine I-131 With or Without Selumetinib in Treating Patients With Recurrent or Metastatic Thyroid Cancer

60 enrolled 12 charts

Thyroid Cancer, Papillary, Thyroid Neoplasms, Adenocarcinoma, Follicular

NCT03223428 2024-07-24

RELAX

Completed

223 enrolled 16 charts

Neuroendocrine Tumors, Serotonin Syndrome

NCT02282059 2024-06-20

The Safety And Efficacy Of Sunitinib In Chinese Patients With Progressive Advanced Or Metastatic Well-Differentiated Unresectable Pancreatic Neuroendocrine Tumors

Completed

100 enrolled 13 charts

Pancreatic Neuroendocrine Tumors

NCT01466036 2024-03-05

Cabozantinib in Advanced Pancreatic Neuroendocrine and Carcinoid Tumors

61 enrolled 9 charts

Carcinoid Tumor, Adenoma, Islet Cell, Neoplasm Metastasis

NCT03008369 2024-02-20

Lenvatinib in Treating Patients With Metastatic or Advanced Pheochromocytoma or Paraganglioma That Cannot Be Removed by Surgery

3 enrolled 9 charts

CNSEndocrine

Paraganglioma, Extra-Adrenal, Pheochromocytoma

NCT00390325 2024-02-06

Sorafenib Tosylate in Treating Patients With Metastatic, Locally Advanced, or Recurrent Medullary Thyroid Cancer

21 enrolled 15 charts

Familial medullary thyroid carcinoma, Carcinoma, Medullary, Multiple Endocrine Neoplasia Type 2a, Multiple Endocrine Neoplasia Type 2b

NCT02244463 2024-01-12

A Phase I/II Study of MLN0128 in Metastatic Anaplastic Thyroid Cancer and Incurably Poorly Differentiated or Radioidodine Refractory Differentiated Thyroid Cancer

46 enrolled 18 charts

Thyroid Neoplasms, Thyroid Carcinoma, Anaplastic

NCT02318784 2023-12-05

Carfilzomib for the Treatment of Patients With Advanced Neuroendocrine Cancers

62 enrolled 10 charts

Carcinoid Tumor, Carcinoma, Neuroendocrine

NCT02422615 2023-11-30

MONALEESA-3

726 enrolled 17 charts 1 FDA

BreastEndocrine

Breast Diseases, Breast Neoplasms, Neoplasms, Neoplasms by Site, Multiple Endocrine Neoplasia Type 1

NCT03176693 2023-11-20

Preoperative Alpha Blockade for Pheochromocytoma

39 enrolled 8 charts

CNSEndocrine

Paraganglioma, Pheochromocytoma

NCT03329079 2023-10-04

Engaging Rural Men With Mobile Technologies for Weight Loss

80 enrolled 10 charts

Weight Loss, Multiple Endocrine Neoplasia Type 1

NCT01607879 2023-09-22

Use of β-hydroxy-β-methylbutyrate to Counteract Muscle Loss in Men With Prostate Cancer on Androgen Ablation

48 enrolled 15 charts

EndocrineGenitourinary

Prostatic Neoplasms, Multiple Endocrine Neoplasia Type 1

NCT02034110 2023-08-21

Efficacy and Safety of the Combination Therapy of Dabrafenib and Trametinib in Subjects With BRAF V600E- Mutated Rare Cancers