Clinical Trials

100 enrolled

Metastatic Digestive System Neuroendocrine Tumor G1

NCT06406465 2026-03-18

A UGT1A1 Genotype-Directed Study of Belinostat Pharmacokinetics and Toxicity

Carcinoma, Neuroendocrine, Neuroendocrine Tumors

NCT06900595 2026-03-18

Testing the Addition of an Anti-Cancer Drug, Cabozantinib to the Immunotherapy Drug Cemiplimab (REGN2810), in Adolescents and Adults With Advanced Adrenocortical Cancer

48 enrolled

Adrenocortical Carcinoma

NCT03412877 2026-03-17

Administration of Autologous T-Cells Genetically Engineered to Express T-Cell Receptors Reactive Against Neoantigens in People With Metastatic Cancer

BreastEndocrineGynecologicNETPlasma cellThoracic

285 enrolled

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Multiple Myeloma, Ovarian Neoplasms, Urogenital Neoplasms, Neuroendocrine Tumors

NCT04665739 2026-03-17

Testing Lutetium Lu 177 Dotatate in Patients With Somatostatin Receptor Positive Advanced Bronchial Neuroendocrine Tumors

70 enrolled

Advanced Lung Neuroendocrine Tumor

NCT05746208 2026-03-17

Lenvatinib Plus Pembrolizumab in Well Differentiated G3 Neuroendocrine Tumors

29 enrolled

Neuroendocrine Tumors

NCT00107289 2026-03-13

Iodine I 131 Metaiodobenzylguanidine in Treating Patients With Recurrent, Progressive, or Refractory Neuroblastoma or Malignant Pheochromocytoma or Paraganglioma

200 enrolled

CNSEndocrine

Neuroblastoma, Pheochromocytoma

NCT06957691 2026-03-09

Fezo-ADT

EndocrineGenitourinary

Adenocarcinoma, Prostatic Neoplasms, Multiple Endocrine Neoplasia Type 1, Hot Flashes

NCT05988918 2026-03-06

Multicenter Trial of ESK981 in Patients With Select Solid Tumors

EndocrineGastrointestinalNET

66 enrolled

Gastro-enteropancreatic neuroendocrine tumor, Adenoma, Islet Cell, Somatostatinoma, Carcinoma, Adenosquamous

NCT06295952 2026-03-04

A Study of Pasireotide in People With Prolactinoma

10 enrolled

Prolactin-Producing Pituitary Tumor

NCT04074135 2026-02-24

Natural History and Management of Von Hippel-Lindau (VHL) Associated Pancreatic Neuroendocrine Tumors

EndocrineGastrointestinalNET

740 enrolled

von Hippel-Lindau Disease, Pancreatic Neoplasms, Neuroectodermal Tumors, Primitive, Neuroendocrine Tumors, Multiple Endocrine Neoplasia Type 1

NCT04924075 2026-02-24

MK-6482-015

322 enrolled 1 FDA

CNSEndocrine

von Hippel-Lindau Disease, Adenoma, Islet Cell, Paraganglioma, Pheochromocytoma

NCT05286814 2026-02-24

PDS01ADC in Combination With Hepatic Artery Infusion Pump (HAIP) and Systemic Therapy for Subjects With Metastatic Colorectal Cancer, Intrahepatic Cholangiocarcinoma, or Metastatic Adrenocortical Carcinoma

EndocrineGastrointestinal

70 enrolled

Cirrhosis, Familial, with Pulmonary Hypertension, Adrenal Cortex Neoplasms, Adrenal Gland Neoplasms, Bile Duct Neoplasms, Colorectal Neoplasms, Adrenocortical Carcinoma, Cholangiocarcinoma

NCT06006013 2026-02-18

Cabozantinib in Combination With Pembrolizumab for the Treatment of Patients With Locally Advanced, Metastatic, or Unresectable Adrenal Cortical Cancer

21 enrolled

Adrenal Cortex Neoplasms, Adrenocortical Carcinoma

NCT03206060 2026-02-17

Lu-177-DOTATATE (Lutathera) in Therapy of Inoperable Pheochromocytoma/ Paraganglioma

130 enrolled

CNSEndocrineNET

Hypertension, Paraganglioma, Pheochromocytoma, Neuroendocrine Tumors

NCT07404176 2026-02-11

TENET

20 enrolled

Neoplasms, Neuroendocrine Tumors

NCT04954820 2026-02-05

ReLUTH

146 enrolled

Neuroendocrine Tumors, Disease Progression

NCT06066333 2026-02-03

Study of Radiotherapy and Pembrolizumab in People With Adrenocortical Carcinoma

12 enrolled

Adrenocortical Carcinoma

NCT06440850 2026-02-02

Vemurafenib and Cobimetinib for the Treatment of Patients With High Risk Differentiated Thyroid Carcinoma With BRAFV600E Mutation

21 enrolled

Thyroid Cancer, Papillary, Adenocarcinoma, Follicular

NCT05088798 2025-12-19

18FDOPA HI

100 enrolled

Hyperinsulinism, Hypoglycemia, Infant, Newborn, Diseases, Insulinoma, Glucose Metabolism Disorders

NCT06926634 2025-12-17

Zanzalintinib Maintenance in Patients With High Grade Neuroendocrine Neoplasms (HG-NENs)

32 enrolled

Neuroendocrine Tumors

NCT04339036 2025-12-10

CapTemY90

70 enrolled

Neuroendocrine Tumors

NCT05263050 2025-12-03

Trial of an Alternative Cabozantinib Dosing Schedule in Metastatic Renal Cell Carcinoma and Neuroendocrine Tumors

EndocrineGenitourinaryNET

111 enrolled

Clear-cell metastatic renal cell carcinoma, Carcinoid Tumor, Carcinoma, Renal Cell, Neuroendocrine Tumors

NCT06333314 2025-12-02

Pan-MSI-ACSE

120 enrolled

EndocrineSarcoma

Neoplasm Metastasis, Neoplasms, Sarcoma, Adrenocortical Carcinoma, Carcinoma, Neuroendocrine

NCT06503146 2025-11-12

18F-Fibroblast Activation Protein Inhibitor ([18F]FAPI-74) PET Imaging for Cancer Detection

CNSEndocrineGastrointestinalGenitourinaryGynecologicOther solid neoplasmSarcomaThoracic

320 enrolled

Urinary Bladder Neoplasms, Carcinoma, Hepatocellular, Mesothelioma, Ovarian Neoplasms, Paraganglioma, Pheochromocytoma, Sarcoma, Stomach Neoplasms, Cholangiocarcinoma, Small Cell Lung Carcinoma

NCT06790706 2025-10-06

IMMUNORARE5

EndocrineGastrointestinalGynecologicHead & NeckNETThoracic

154 enrolled

Gastro-enteropancreatic neuroendocrine tumor, Carcinoid Tumor, Thymoma, Gestational Trophoblastic Disease, Thyroid Carcinoma, Anaplastic

NCT07085572 2025-10-06

INTERVAL

31 enrolled

Adrenocortical Carcinoma

NCT03127774 2025-10-03

Surgery and Heated Intraperitoneal Chemotherapy for Adrenocortical Carcinoma

30 enrolled

EndocrineGynecologic

Peritoneal Neoplasms, Adrenocortical Carcinoma

NCT04325425 2025-09-30

FOLFIRINEC

218 enrolled

Carcinoma, Neuroendocrine

NCT07167329 2025-09-11

BELIEVE-VHL

CNSEndocrineGenitourinary

100 enrolled

Carcinoma, Renal Cell, von Hippel-Lindau Disease, Paraganglioma, Pheochromocytoma, Neuroectodermal Tumors, Primitive, Hemangioblastoma

NCT06893783 2025-09-08

DeLLight

Carcinoma, Neuroendocrine

NCT06374602 2025-09-05

Efficacy of Pembrolizumab and Lenvatinib in Patients With Anaplastic Thyroid Cancer

20 enrolled

Thyroid Carcinoma, Anaplastic

NCT06359847 2025-08-24

Study of ST-1898 in Locally Advanced or Metastatic Radioiodine-Refractory Differentiated Thyroid Cancer

Differentiated Thyroid Carcinoma

NCT06683846 2025-08-24

Ivonescimab in the Treatment of Multiple Advanced Tumors

CNSDermatologicEndocrineGenitourinarySarcoma

400 enrolled

Urachal cancer, Carcinoma, Carcinoma, Basal Cell, Carcinoma, Transitional Cell, Kidney Neoplasms, Paget Disease, Extramammary, Paraganglioma, Penile Neoplasms, Pheochromocytoma, Prostatic Neoplasms, Rhabdomyosarcoma, Sarcoma, Angiomyolipoma, Carcinoma, Neuroendocrine, Perivascular Epithelioid Cell Neoplasms

NCT06345079 2025-08-14

STOPNET

78 enrolled

Neuroendocrine Tumors

NCT04268121 2025-07-23

NEONEC

EndocrineGastrointestinal

78 enrolled

Gastrointestinal Neoplasms, Carcinoma, Neuroendocrine

NCT04837885 2025-07-23

LUTARTERIAL

23 enrolled

Neoplasms, Neuroendocrine Tumors

NCT06395402 2025-07-22

LUMOD-ID

120 enrolled

Neuroendocrine Tumors

NCT03935893 2025-07-10

Adoptive Transfer of Tumor Infiltrating Lymphocytes for Advanced Solid Cancers

DermatologicEndocrineGastrointestinalNETOther solid neoplasmSarcomaThoracic

240 enrolled

Turcot syndrome, Mesothelioma, Pancreatic Neoplasms, Sarcoma, Stomach Neoplasms, Colorectal Neoplasms, Carcinoma, Merkel Cell, Neoplasms, Squamous Cell, Neuroendocrine Tumors, Microsatellite Instability

NCT06959641 2025-06-11

XL092 for the Treatment of Locally Advanced or Metastatic Radioiodine Refractory Differentiated Thyroid Cancer

33 enrolled

Thyroid Cancer, Papillary, Adenocarcinoma, Follicular

NCT06831175 2025-06-03

Phase II Study of PD-1 Inhibitor Combined With Apatinib and Mitotane in the Treatment of Advanced Adrenal Cortical Carcinoma

28 enrolled

Adrenal Gland Neoplasms, Adrenocortical Carcinoma

NCT04888481 2025-05-07

68Ga-HA-DOTATATE Imaging of Suspected Somatostatin Receptor Positive Tumors

600 enrolled

Neuroendocrine Tumors

NCT06587802 2025-04-29

Phase II Study of PD-1 Antibody Combined With Radiotherapy in Recurrent or Metastatic Adrenal Cortical Carcinoma

18 enrolled

Adrenocortical Carcinoma

NCT05852223 2025-04-13

NePenThe

25 enrolled

Differentiated Thyroid Cancer

NCT05563467 2025-04-02

PEMBR-01

24 enrolled

Adrenocortical Carcinoma

NCT05165407 2025-03-14

NESSIE

30 enrolled

Neuroendocrine Tumors

NCT05879055 2024-12-19

A Study of PM8002 in Combination With Chemotherapy in Patients With NEN

Neuroendocrine Tumors

NCT05668962 2024-12-12

Restor. I-131 Upt. + Selpercatinib in RET F-P RAI-R TC

30 enrolled

Thyroid Cancer, Papillary, Thyroid Neoplasms, Adenocarcinoma, Follicular

NCT02185443 2024-12-09

Stereotactic Body Radiation Therapy (SBRT) for Unresectable Liver Metastases