Clinical Trials Browser

Terminated × NIH × Endocrine × Clear all

NCT03165721 2026-02-18

A Phase II Trial of the DNA Methyl Transferase Inhibitor, Guadecitabine (SGI-110), in Children and Adults With Wild Type GIST,Pheochromocytoma and Paraganglioma Associated With Succinate Dehydrogenase Deficiency and HLRCC-associated Kidney Cancer

Phase 2 Terminated

9 enrolled 11 charts

CNSEndocrineGastrointestinalGenitourinarySarcoma

Carcinoma, Renal Cell, Kidney Neoplasms, Paraganglioma, Pheochromocytoma, Gastrointestinal Stromal Tumors

NCT04538378 2025-01-27

Olaparib (LYNPARZA) Plus Durvalumab (IMFINZI) in EGFR-Mutated Adenocarcinomas That Transform to Small Cell Lung Cancer (SCLC) and Other Neuroendocrine Tumors

Phase 2 Terminated

4 enrolled 11 charts

EndocrineThoracic

EGFR-Mutated Non-Small-Cell Lung Carcinoma

NCT04447014 2023-01-17

Natural History Study of Children and Adults With Adrenocortical Cancer (ACC)

Adrenal Cortex Neoplasms, Adrenocortical Carcinoma

NCT02315625 2020-09-09

Study of Mutation-Targeted Therapy With Sunitinib or Everolimus in People With Advanced Low- or Intermediate-Grade Neuroendocrine Tumors of the Gastrointestinal Tract and Pancreas With or Without Cytoreductive Surgery

Phase 2 Terminated

16 enrolled 15 charts

Neoplasms, Carcinoma, Neuroendocrine, Neuroendocrine Tumors

NCT01086696 2019-12-17

A Pilot Study of F-18 Paclitaxel (FPAC) PET for Evaluating Drug Delivery of Solid Tumors in Breast, Lung, Renal, and Adrenal Cancers

Phase EARLY_PHASE1 Terminated

BreastEndocrineGenitourinaryThoracic

Adrenal Gland Neoplasms, Breast Neoplasms, Kidney Neoplasms, Lung Neoplasms

NCT00005664 2019-12-16

Evaluation of Patients With Endocrine-Related Conditions

Adrenal Insufficiency, Obesity, Pituitary Neoplasms

NCT03002623 2018-12-21

CUDC-907 Treatment in People With Metastatic and Locally Advanced Thyroid Cancer

Phase 2 Terminated

7 enrolled 13 charts

EndocrineHead & Neck

Thyroid Neoplasms, Thyroid Carcinoma, Anaplastic

NCT01348698 2018-11-26

Evaluation of Molecular Markers in Adrenal Tumors

74 enrolled 10 charts

Adrenal Gland Neoplasms, Pheochromocytoma

NCT02001051 2018-06-14

Study of Adrenalectomy Versus Observation for Subclinical Hypercortisolism

Phase 2 Terminated

4 enrolled 10 charts

Adrenal incidentaloma, Adrenal Gland Neoplasms, Cushing Syndrome, Diabetes Mellitus, Hypercholesterolemia, Hypertension, Obesity, Osteoporosis

NCT00126568 2018-01-19

Sorafenib in Treating Patients With Advanced Anaplastic Thyroid Cancer

Phase 2 Terminated

20 enrolled 10 charts

EndocrineHead & Neck

Thyroid Neoplasms, Thyroid Carcinoma, Anaplastic

NCT01340794 2017-09-21

Pazopanib Hydrochloride in Treating Patients With Advanced or Progressive Malignant Pheochromocytoma or Paraganglioma

Phase 2 Terminated

7 enrolled 8 charts

Paraganglioma, Paraganglioma, Extra-Adrenal, Pheochromocytoma

NCT01088763 2014-11-05

Gamma-Secretase Inhibitor RO4929097 in Treating Young Patients With Relapsed or Refractory Solid Tumors, CNS Tumors, Lymphoma, or T-Cell Leukemia

Phase 1 Terminated

CNSEndocrineLymphoidOther hematologic neoplasmSarcoma

Familial ependymoma, Adenoma, Basophil, Adenoma, Chromophobe, Adenoma, Acidophil, Astrocytoma, Burkitt Lymphoma, Medulloblastoma, Oligodendroglioma, Pituitary Neoplasms, Recurrence, Spinal Cord Neoplasms, Prolactinoma, Choroid Plexus Neoplasms, Lymphoma, Large-Cell, Anaplastic, Rhabdoid Tumor, Optic Nerve Glioma, Leukemia, Large Granular Lymphocytic, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Dendritic Cell Sarcoma, Interdigitating

NCT00778817 2014-04-29

IMC-A12 With Mitotane vs Mitotane Alone in Recurrent, Metastatic, or Primary ACC That Cannot Be Removed by Surgery

Phase 2 Terminated

20 enrolled 17 charts

Adrenocortical Carcinoma

NCT00095693 2014-01-16

Sorafenib Tosylate in Treating Patients With Locally Advanced, Metastatic, or Locally Recurrent Thyroid Cancer

Phase 2 Terminated

EndocrineHead & Neck

Thyroid Cancer, Papillary, Thyroid Neoplasms, Adenocarcinoma, Follicular, Thyroid Carcinoma, Anaplastic

NCT00084461 2013-06-04

Romidepsin in Treating Patients With Locally Advanced or Metastatic Neuroendocrine Tumors

Phase 2 Terminated

Glucagonoma, Insulinoma, Somatostatinoma, Gastrinoma, Carcinoma, Islet Cell