Clinical Trials Browser

Interventional × Cachexia × Gastrointestinal × Clear all

NCT06989437 2026-02-06

A Study to Learn About the Medicine Ponsegromab in Adults With Cancer of the Pancreas Which Has Spread and Caused Significant Body Weight Loss and Fatigue

Phase 2/3 Recruiting

Gastrointestinal

Anorexia, Cachexia, Fatigue, Neoplasm Metastasis, Neoplasms, Pancreatic Neoplasms, Weight Loss

NCT07356037 2026-01-21

Nanocrystalline Megestrol Acetate for Cachectic Stage Locally Advanced Hepatocellular Carcinoma

Phase 3 Not yet recruiting

Gastrointestinal

Cachexia, Carcinoma, Hepatocellular

NCT06937177 2025-12-12

Safely Optimizing Body Weight With TCMCB07 in Patients With Newly Diagnosed Metastatic Colorectal Cancer Undergoing Chemotherapy

Phase 2 Recruiting

Gastrointestinal

Cachexia, Colorectal Neoplasms, Weight Loss

NCT04844970 2025-11-17

Anamorelin Study for Advanced Pancreatic Cancer

Phase 2 Terminated

4 enrolled 12 charts

Gastrointestinal

Anorexia, Cachexia, Pancreatic Neoplasms, Weight Loss

NCT05546476 2025-05-31

PROACC-1

Phase 2 Completed

187 enrolled 24 charts

GastrointestinalThoracic

Anorexia, Cachexia, Carcinoma, Non-Small-Cell Lung, Fatigue, Neoplasms, Pancreatic Neoplasms, Colorectal Neoplasms, Weight Loss

NCT05420259 2024-03-19

Combined Exercise and Nutritional Intervention in GI Cancer Patients

Phase NA Recruiting

Gastrointestinal

Cachexia, Motor Activity, Pancreatic Neoplasms, Stomach Neoplasms, Malnutrition

NCT04803305 2024-01-12

Study to Compare the Effects of Repeated Doses of an Investigational New Drug and a Placebo on Appetite in Advanced Cancer and Anorexia

Phase 1 Completed

18 enrolled 14 charts

BreastGastrointestinalGenitourinaryGynecologicThoracic

Anorexia, Breast Neoplasms, Cachexia, Carcinoma, Non-Small-Cell Lung, Fatigue, Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Colorectal Neoplasms, Weight Loss

NCT03245658 2023-12-18

The Effect of Cannabis in Pancreatic Cancer

Phase 2 Withdrawn

Gastrointestinal

Anorexia, Cachexia, Marijuana Abuse, Neoplasms, Pancreatic Neoplasms

NCT04299048 2023-12-14

Study to Assess the Safety and Tolerability of Repeated Doses of an Investigational New Drug in Patients With Cancer and Cachexia.

Phase 1 Completed

11 enrolled 13 charts

GastrointestinalThoracic

Anorexia, Cachexia, Carcinoma, Non-Small-Cell Lung, Fatigue, Muscular Atrophy, Pancreatic Neoplasms, Colorectal Neoplasms, Weight Loss

NCT04131426 2023-08-15

Evaluating the Combined Intervention of Nutritional Supplementation (Remune) and Exercise in Patients With Cancer Cachexia

Phase 1 Completed

GastrointestinalThoracic

Cachexia, Gastrointestinal Neoplasms, Lung Neoplasms, Motor Activity, Neoplasms, Weight Loss

NCT02515513 2023-06-28

The Role of Muscle Cachexia in Pancreatic Cancer

Phase NA Withdrawn

Gastrointestinal

Cachexia, Pancreatic Neoplasms

NCT05856500 2023-05-18

A Study of Creatine Combined With Curcumin in the Intervention of Early Cachexia in Upper Gastrointestinal Tumors

Phase NA Unknown

Gastrointestinal

Cachexia, Esophageal Neoplasms, Stomach Neoplasms

NCT04600154 2023-01-19

MS-20 on Gut Microbiota and Risk/Severity of Cachexia in Pancreatic Cancer Patients

Phase NA Unknown

Gastrointestinal

Cachexia, Pancreatic Neoplasms

NCT03172403 2022-08-25

MYOCAC

Phase NA Terminated

Gastrointestinal

Cachexia, Digestive System Neoplasms

NCT04907864 2021-06-01

MIRACLE

Phase 2 Unknown

GastrointestinalThoracic

Biliary Tract Neoplasms, Cachexia, Lung Neoplasms, Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Colorectal Neoplasms

NCT04802486 2021-03-17

The Effects of a 12 Week Home-based Exercise Intervention on Physical Performance in Patients With Cancers of the Gastrointestinal Tract With Pre- Cachexia or Cachexia

Phase NA Completed

Gastrointestinal

Cachexia, Gastrointestinal Neoplasms, Motor Activity, Weight Loss

NCT03207724 2020-12-30

OnFX

Phase 1 Completed

Gastrointestinal

Adenocarcinoma, Cachexia, Disease, Pancreatic Neoplasms, Weight Loss

NCT02148159 2019-01-17

Acupuncture for Unintentional Weight Loss and Anorexia With GI Cancer

Phase NA Completed

Gastrointestinal

Anorexia, Cachexia, Gastrointestinal Neoplasms, Neoplasms

NCT02199912 2018-11-23

ANC2

Phase NA Completed

Gastrointestinal

Cachexia, Neoplasms, Colorectal Neoplasms

NCT02500004 2018-08-03

BAT-Cachexia

Phase NA Completed

Gastrointestinal

Cachexia, Neoplasms, Pancreatic Neoplasms, Pulmonary Disease, Chronic Obstructive

NCT00637728 2016-06-23

Treatment of Cancer-anorexia Using Megestrol Acetate Concentrated Suspension in Lung or Pancreatic Cancer Patients

Phase 3 Terminated

5 enrolled 8 charts

GastrointestinalThoracic

Anorexia, Body Weight, Cachexia, Lung Neoplasms, Pancreatic Neoplasms, Weight Loss

NCT01433263 2016-03-02

Clinical Study of BYM338 for the Treatment of Unintentional Weight Loss in Patients With Cancer of the Lung or the Pancreas

Phase 2 Completed

57 enrolled 16 charts

GastrointestinalThoracic

Adenocarcinoma, Cachexia, Emaciation, Lung Neoplasms, Pancreatic Neoplasms, Wasting Syndrome

NCT01132547 2015-07-02

Cyproheptadine in Preventing Weight Loss in Children Receiving Chemotherapy for Cancer

Phase 3 Terminated

22 enrolled 9 charts

CNSGastrointestinalGenitourinaryGynecologicLymphoidSarcoma

Familial ependymoma, Ovarian Germ Cell Cancer, Astrocytoma, Body Weight Changes, Bone Neoplasms, Cachexia, Chondrosarcoma, Fibrosarcoma, Glioblastoma, Hemangiosarcoma, Liposarcoma, Medulloblastoma, Nausea, Neoplasms, Wilms Tumor, Neuroblastoma, Oligodendroglioma, Sarcoma, Sarcoma, Ewing, Mast-Cell Sarcoma, Osteosarcoma, Testicular Neoplasms, Vomiting, Choroid Plexus Neoplasms, Lymphoma, Large-Cell, Anaplastic, Hepatoblastoma, Sarcoma, Endometrial Stromal, Neuroectodermal Tumors, Primitive, Peripheral, Neoplasms, Neuroepithelial, Optic Nerve Glioma

NCT01395563 2015-03-13

STOPC

Phase NA Withdrawn

Gastrointestinal

Cachexia, Muscular Diseases, Pancreatic Neoplasms

NCT00467844 2014-07-11

Study of GTx-024 on Muscle Wasting (Cachexia) Cancer.

Phase 2 Completed

159 enrolled 11 charts

GastrointestinalLymphoidThoracic

Cachexia, Carcinoma, Non-Small-Cell Lung, Lymphoma, Non-Hodgkin, Muscular Atrophy, Colorectal Neoplasms

NCT00710632 2013-09-17

Screening to Predict Weight Loss in Patients With Cancer

Phase NA Unknown

GastrointestinalOther hematologic neoplasmThoracic

Cachexia, Gastrointestinal Neoplasms, Lung Neoplasms, Hematologic Neoplasms

NCT00513357 2012-12-11

Melatonin Versus Placebo and the Effect on Appetite in Advanced Cancer Patients

Phase 3 Completed

82 enrolled 7 charts

GastrointestinalThoracic

Anorexia, Cachexia, Gastrointestinal Neoplasms, Lung Neoplasms, Weight Loss

NCT00060502 2011-05-17

A Study of the Safety and Effectiveness of Infliximab (Remicade) in Patients With Pancreatic Cancer Related Cachexia

Phase 2 Completed

Classical hematologyGastrointestinal

Anemia, Anorexia, Cachexia, Pancreatic Neoplasms