Clinical Trials

44 enrolled

Phase 2 Active not recruiting

Adenocarcinoma, Carcinoma, Colorectal Neoplasms

NCT05063565 2026-03-02

ROWAN

100 enrolled

Phase 2 Active not recruiting

Adenocarcinoma, Carcinoma, Digestive System Diseases, Digestive System Neoplasms, Carcinoma, Hepatocellular, Liver Diseases, Liver Neoplasms, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Glandular and Epithelial

NCT05014776 2026-02-24

Study of CRS-207, Pembrolizumab, Ipilimumab, and Tadalafil in Metastatic Pancreatic Cancer

17 enrolled 8 charts

Adenocarcinoma, Carcinoma, Pancreatic Neoplasms

NCT04379596 2026-02-23

DG-03

450 enrolled

Adenocarcinoma, Carcinoma, Esophageal Neoplasms, Stomach Neoplasms

NCT03993353 2026-02-12

Tadalafil and Pembrolizumab in Recurrent or Metastatic Head and Neck Cancer

GastrointestinalHead & Neck

7 enrolled 14 charts

Pyridoxine-dependent epilepsy, Parkinson Disease 4, Autosomal Dominant Lewy Body, Squamous Cell Carcinoma of Head and Neck, Carcinoma, Esophageal Neoplasms, Head and Neck Neoplasms, Mouth Neoplasms, Neoplasm Metastasis, Neoplasms

NCT07281768 2025-12-15

Capecitabine/Oxaliplatin Chemotherapy and Cemiplimab With or Without Fianlimab or REGN7075 in Locally Advanced Rectal Cancer

Phase 2 Not yet recruiting

66 enrolled

Adenocarcinoma, Carcinoma, Rectal Neoplasms, Colorectal Neoplasms

NCT06001658 2025-12-03

Perioperative Gemcitabine, Cisplatin, and Pembrolizumab in Potentially Resectable Biliary Tract Cancers

27 enrolled

Biliary Tract Neoplasms, Carcinoma

NCT06941857 2025-12-03

NC410 and FOLFIRINOX in Combination With Nivolumab With or Without Ipilimumab in Patients With Untreated Metastatic Pancreatic Cancer

20 enrolled

Carcinoma, Pancreatic Neoplasms

NCT07246668 2025-11-24

A Phase II Single-Arm Clinical Study to Evaluate the Efficacy and Safety of Carbon Ion Radiotherapy With Atezolizumab and Bevacizumab Combination Therapy in Patients With Advanced Hepatocellular Carcinoma

52 enrolled

Carcinoma, Carcinoma, Hepatocellular, Liver Neoplasms

NCT07145801 2025-10-07

TARE

Phase 2 Not yet recruiting

Carcinoma, Carcinoma, Hepatocellular, Liver Neoplasms

NCT06813079 2025-02-18

Using Tumor Models to Determine Treatments

25 enrolled

Phase 2 Not yet recruiting

Carcinoma, Carcinoma, Pancreatic Ductal

NCT06551896 2024-08-13

Pemigatinib and Immune Checkpoint Inhibitor Treated FGFR1/2/3 Alteration Advanced Solid Tumor

BreastGastrointestinalGenitourinarySarcomaThoracic

Breast Neoplasms, Carcinoma, Carcinoma, Transitional Cell, Lung Neoplasms, Sarcoma, Stomach Neoplasms

NCT03190265 2024-08-07

Study of CRS-207, Nivolumab, and Ipilimumab With or Without GVAX Pancreas Vaccine (With Cy) in Patients With Pancreatic Cancer

61 enrolled 11 charts

Adenocarcinoma, Carcinoma, Neoplasms, Pancreatic Neoplasms

NCT06134193 2023-11-18

Combination Therapy of HAIC, Surufatinib and Tislelizumab for Unresectable or Metastatic Biliary Tract Cancer

41 enrolled

Carcinoma, Gallbladder Neoplasms, Cholangiocarcinoma

NCT05494060 2023-11-07

EXPLORING

80 enrolled

Carcinoma, Digestive System Diseases, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Stomach Neoplasms

NCT04962958 2023-06-22

Hepatic Artery Infusion Chemotherapy Plus Donafenib in Patients With Hepatocellular Carcinoma After Surgery

Carcinoma, Digestive System Neoplasms, Carcinoma, Hepatocellular, Liver Neoplasms

NCT05913661 2023-06-22

Pemigatinib Combined With PD-1 Inhibitor in Unresectable or Metastatic Intrahepatic Cholangiocarcinoma

Carcinoma, Digestive System Neoplasms, Cholangiocarcinoma

NCT05541146 2023-03-23

Intraperitoneal Chemotherapy in Gastric Cancer With Peritoneal Carcinomatosis

GastrointestinalGynecologic

Carcinoma, Peritoneal Neoplasms, Stomach Neoplasms

NCT02115542 2021-10-12

Single Agent Regorafenib in Refractory Advanced Biliary Cancers

39 enrolled 11 charts

Bile Duct Diseases, Bile Duct Neoplasms, Carcinoma, Gallbladder Diseases, Gallbladder Neoplasms, Neoplasm Metastasis

NCT00671645 2020-10-19

Preoperative Combined RadioChemo-Molecular Target Therapy With Capecitabine, Bevacizumab, and Radiotherapy

8 enrolled

Carcinoma, Erythema Multiforme, Rectal Neoplasms

NCT03549338 2020-09-28

Sym004 Versus Futuximab or Modotuximab in Patients With mCRC

2 enrolled 9 charts

Carcinoma, Colorectal Neoplasms

NCT03544723 2020-06-09

Safety and Efficacy of p53 Gene Therapy Combined With Immune Checkpoint Inhibitors in Solid Tumors.

BreastDermatologicGastrointestinalGenitourinaryGynecologicLymphoidThoracic

40 enrolled

Carcinoma, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Esophageal Neoplasms, Hodgkin Disease, Liver Neoplasms, Lymphoma, Melanoma, Stomach Neoplasms, Carcinoma, Merkel Cell, Neoplasms, Squamous Cell, Small Cell Lung Carcinoma, Triple Negative Breast Neoplasms

NCT01088815 2019-04-26

Hedgehog Inhibitors for Metastatic Adenocarcinoma of the Pancreas

98 enrolled 14 charts

Adenocarcinoma, Carcinoma, Digestive System Diseases, Digestive System Neoplasms, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Pancreatic Diseases, Pancreatic Neoplasms

NCT01037049 2018-09-17

Optimum Timing for Surgery After Pre-operative Radiotherapy 6 vs 12 Weeks

237 enrolled

Adenocarcinoma, Carcinoma, Adenocarcinoma, Mucinous, Digestive System Diseases, Digestive System Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Intestinal Diseases, Intestinal Neoplasms, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Glandular and Epithelial, Rectal Diseases, Rectal Neoplasms, Colorectal Neoplasms, Neoplasms, Cystic, Mucinous, and Serous

NCT00417287 2018-05-16

Phase II Study of PX-12 in Patients With Advanced Pancreatic Cancer

17 enrolled

Carcinoma, Neoplasms, Pancreatic Neoplasms

NCT02473094 2017-11-28

NEOMETRE

3 enrolled

Adenocarcinoma, Carcinoma, Rectal Neoplasms

NCT00682786 2017-10-06

Genotype-directed Neoadjuvant Chemoradiation for Rectal Carcinoma

135 enrolled 17 charts

Carcinoma, Neoplasms, Rectal Neoplasms

NCT01177007 2017-08-28

Intra-arterial Y-90 TheraSpheres for Hepatic Metastases From Solid Tumors

EndocrineGastrointestinalNET

50 enrolled 10 charts

Adenocarcinoma, Carcinoma, Colonic Diseases, Digestive System Diseases, Digestive System Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Intestinal Diseases, Intestinal Neoplasms, Liver Diseases, Liver Neoplasms, Neoplasm Metastasis, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Glandular and Epithelial, Neoplasms, Nerve Tissue, Neoplastic Processes, Pathologic Processes, Rectal Diseases, Colorectal Neoplasms, Neuroectodermal Tumors, Carcinoma, Neuroendocrine, Neuroendocrine Tumors

NCT00386516 2017-08-01

Study to Test the Benefit and Safety of GM-CT-01 in Combination With 5-FU to Treat Bile Duct and Gall Bladder Cancer

Phase 2 Withdrawn

Bile Duct Neoplasms, Carcinoma, Gallbladder Neoplasms, Neoplasm Metastasis, Neoplasms, Recurrence, Cholangiocarcinoma

NCT01576380 2017-02-27

A Phase II Study to Evaluate Efficacy and Safety of Dovitinib (TKI258) in Advanced Scirrhous Gastric Carcinoma Patients

11 enrolled

Carcinoma, Adenocarcinoma, Scirrhous, Genital Diseases, Female, Linitis Plastica, Neoplasms, Neoplasms by Site, Stomach Diseases, Stomach Neoplasms

NCT00576056 2017-02-15

Effectiveness and Safety Study of TACE Plus Oral Sorafenib for Unresectable HCC

19 enrolled 7 charts

Carcinoma, Carcinoma, Hepatocellular

NCT01507103 2017-01-13

SPRINT

124 enrolled 9 charts

GastrointestinalGynecologic

Carcinoma, Neoplasms, Neoplasms by Site, Rectal Neoplasms

NCT01342653 2016-11-21

HIPEC

Phase 2 Suspended

50 enrolled

Carcinoma, Neoplasms, Peritoneal Neoplasms, Stomach Neoplasms

NCT00975039 2016-04-18

Study Using WST11 in Patients With Non-Resectable or Inoperable Cholangiocarcinoma

8 enrolled

Carcinoma, Cholangiocarcinoma

NCT01469598 2015-12-29

Study of Docetaxel and Gemcitabine in Metastatic Esophageal Squamous Cell Cancer

24 enrolled

Esophageal Squamous Cell Carcinoma, Carcinoma

NCT00752570 2015-09-02

A Phase 2, Randomized, Double Blind, Placebo Controlled Study of AMG 386 in Combination With FOLFIRI in Subjects With Previously Treated Metastatic Colorectal Carcinoma

144 enrolled

Carcinoma, Colonic Neoplasms, Gastrointestinal Neoplasms, Neoplasm Metastasis, Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT01215578 2015-04-30

NET

EndocrineGastrointestinalNET

33 enrolled

Adenocarcinoma, Adenoma, Carcinoma, Digestive System Diseases, Digestive System Neoplasms, Endocrine System Diseases, Endocrine Gland Neoplasms, Adenoma, Islet Cell, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Glandular and Epithelial, Neoplasms, Nerve Tissue, Pancreatic Diseases, Pancreatic Neoplasms, Neuroectodermal Tumors, Neuroendocrine Tumors

NCT01019382 2014-12-04

A Study of the Effect of Gemcitabine With Fish Oil in Patients With Advanced Pancreatic Cancer

50 enrolled

Carcinoma, Neoplasms, Pancreatic Neoplasms

NCT01215565 2014-03-13

Fibrolam

4 enrolled

Fibrolamellar hepatocellular carcinoma, Adenocarcinoma, Carcinoma, Digestive System Neoplasms, Fibrosis, Carcinoma, Hepatocellular, Liver Diseases, Liver Neoplasms, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Glandular and Epithelial, Pathologic Processes

NCT00035087 2013-12-04

EPO906 Therapy in Patients With Advanced Colorectal Cancer

62 enrolled

Carcinoma, Colonic Neoplasms, Neoplasms, Colorectal Neoplasms

NCT00111774 2013-05-14

Evaluating ABX-EGF in Patients With Metastatic ColorectalCarcinoma

150 enrolled

Carcinoma, Colonic Neoplasms, Neoplasm Metastasis, Rectal Neoplasms, Colorectal Neoplasms

NCT00363051 2013-05-10

Safety/Efficacy of Everolimus in Adults With Advanced Pancreatic Neuroendocrine Cancer Not Responsive to Chemotherapy

EndocrineGastrointestinalNET

160 enrolled 17 charts

Carcinoma, Neoplasms, Pancreatic Neoplasms, Carcinoma, Islet Cell, Carcinoma, Neuroendocrine, Neuroendocrine Tumors

NCT00401570 2013-01-30

A Study of Volociximab in Combination With Gemcitabine in Metastatic Pancreatic Cancer

40 enrolled

Carcinoma, Neoplasms, Pancreatic Neoplasms

NCT01556815 2012-04-25

Sorafenib Combined With Transarterial Chemoembolization in Treating HBV-infected Patients With Intermediate Hepatocellular Carcinoma

40 enrolled