Clinical Trials Browser

Pyridoxine-dependent epilepsy, Parkinson Disease 4, Autosomal Dominant Lewy Body, Squamous Cell Carcinoma of Head and Neck, Carcinoma, Esophageal Neoplasms, Head and Neck Neoplasms, Mouth Neoplasms, Neoplasm Metastasis, Neoplasms

NCT06027086 2026-02-12

DRP-104 (Glutamine Antagonist) in Combination With Durvalumab in Patients With Advanced Stage Fibrolamellar Carcinoma (FLC)

Phase 1/2 Recruiting

27 enrolled

Gastrointestinal

Fibrolamellar hepatocellular carcinoma, Carcinoma

NCT07365124 2026-01-26

MRinRT

Not yet recruiting

165 enrolled

CNSGastrointestinal

Carcinoma, Esophageal Neoplasms, Glioblastoma, Neoplasms, Neurologic Manifestations, Pancreatic Neoplasms, Stomach Neoplasms

NCT07281768 2025-12-15

Capecitabine/Oxaliplatin Chemotherapy and Cemiplimab With or Without Fianlimab or REGN7075 in Locally Advanced Rectal Cancer

Phase 2 Not yet recruiting

66 enrolled

Gastrointestinal

Adenocarcinoma, Carcinoma, Rectal Neoplasms, Colorectal Neoplasms

NCT06564623 2025-12-05

Targeting Driver Oncogenes With a Peptide Vaccine Plus Durvalumab and Tremelimumab for Patients With Biliary Tract Cancers (BTC)

Phase 1 Recruiting

25 enrolled

Gastrointestinal

Diabetes Mellitus, Insulin-Dependent, 12, Biliary Tract Neoplasms, Carcinoma

NCT06001658 2025-12-03

Perioperative Gemcitabine, Cisplatin, and Pembrolizumab in Potentially Resectable Biliary Tract Cancers

Phase 2 Recruiting

27 enrolled

Gastrointestinal

Biliary Tract Neoplasms, Carcinoma

NCT06782932 2025-12-03

Comparing Neoadjuvant/Adjuvant GVAX vs a mKRASvax Given With Anti-PD-1 and Anti-CD137 for Surgically Resectable Pancreatic Cancer

Phase 1/2 Recruiting

38 enrolled

Gastrointestinal

Adenocarcinoma, Carcinoma, Pancreatic Neoplasms

NCT06941857 2025-12-03

NC410 and FOLFIRINOX in Combination With Nivolumab With or Without Ipilimumab in Patients With Untreated Metastatic Pancreatic Cancer

Phase 2 Recruiting

20 enrolled

Gastrointestinal

Carcinoma, Pancreatic Neoplasms

NCT07252323 2025-11-26

A Single-arm Phase II Clinical Study Investigating the Safety and Efficacy of Carbon Ion Radiotherapy in Patients With Hepatocellular Carcinoma Previously Treated With Transarterial Radioembolization (TARE)

Phase NA Recruiting

48 enrolled

Gastrointestinal

Carcinoma, Carcinoma, Hepatocellular

NCT07246668 2025-11-24

A Phase II Single-Arm Clinical Study to Evaluate the Efficacy and Safety of Carbon Ion Radiotherapy With Atezolizumab and Bevacizumab Combination Therapy in Patients With Advanced Hepatocellular Carcinoma

Phase 2 Recruiting

52 enrolled

Gastrointestinal

Carcinoma, Carcinoma, Hepatocellular, Liver Neoplasms

NCT03618381 2025-11-20

EGFR806 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults

Phase 1 Active not recruiting

44 enrolled

CNSGastrointestinalGenitourinaryOther solid neoplasmSarcoma

Carcinoma, Neoplasms, Germ Cell and Embryonal, Wilms Tumor, Neuroblastoma, Retinoblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Sarcoma, Synovial, Hepatoblastoma, Sarcoma, Clear Cell, Neurofibrosarcoma, Rhabdoid Tumor, Desmoplastic Small Round Cell Tumor

NCT04483778 2025-11-20

B7H3 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults

Phase 1 Active not recruiting

68 enrolled

CNSDermatologicGastrointestinalGenitourinaryOther solid neoplasmSarcoma

Carcinoma, Melanoma, Neoplasms, Germ Cell and Embryonal, Wilms Tumor, Neuroblastoma, Retinoblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Sarcoma, Synovial, Hepatoblastoma, Sarcoma, Clear Cell, Neurofibrosarcoma, Rhabdoid Tumor, Desmoplastic Small Round Cell Tumor

NCT07201012 2025-11-17

SMT-SL

Phase NA Not yet recruiting

150 enrolled

DermatologicGastrointestinal

Carcinoma, Carcinoma, Basal Cell, Carcinoma, Squamous Cell, Colorectal Neoplasms, Hereditary Nonpolyposis, Skin Neoplasms, Muir-Torre Syndrome

NCT04897321 2025-10-24

B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)

Phase 1 Recruiting

32 enrolled

CNSDermatologicGastrointestinalGenitourinarySarcoma

Adrenal Cortex Neoplasms, Carcinoma, Melanoma, Neoplasms, Germ Cell and Embryonal, Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Hepatoblastoma, Sarcoma, Clear Cell, Neurofibrosarcoma, Rhabdoid Tumor, Desmoplastic Small Round Cell Tumor

NCT07145801 2025-10-07

TARE

Phase 2 Recruiting

30 enrolled

Gastrointestinal

Carcinoma, Carcinoma, Hepatocellular, Liver Neoplasms

NCT07180459 2025-09-18

The Treatment of Unresectable Liver Cancer With E-TACE Combined With Donafenib：A Prospective, Single-arm, Multicenter, Observational Study

Not yet recruiting

118 enrolled

Gastrointestinal

Carcinoma, Carcinoma, Hepatocellular

NCT06096688 2025-09-04

Discovering New Targets for Colorectal and Endometrial Cancer Risk Reduction

Recruiting

1,120 enrolled

GastrointestinalGynecologic

Carcinoma, Neoplastic Syndromes, Hereditary, Polyps, Colorectal Neoplasms, Endometrial Neoplasms

NCT06950814 2025-04-30

Prognostic Impact of Adjuvant Therapy in Primary Hepatic Sarcomatoid Carcinoma

Recruiting

50 enrolled

Gastrointestinal

Carcinoma, Liver Neoplasms

NCT05340569 2025-03-20

DWI-PDAC

Phase NA Completed

40 enrolled

GastrointestinalGynecologic

Carcinoma, Pancreatic Neoplasms, Peritoneal Neoplasms

NCT05623787 2025-03-20

DWI-HighRisk

Phase NA Active not recruiting

30 enrolled

GastrointestinalGynecologic

Appendiceal Neoplasms, Carcinoma, Peritoneal Neoplasms, Colorectal Neoplasms

NCT05297734 2025-03-19

Comparative Effectiveness Trial of Two Supportive Cancer Care Delivery Models for Adults With Cancer

Phase NA Recruiting

2,996 enrolled

BreastCNSDermatologicGastrointestinalGenitourinaryGynecologicMyeloidSarcomaThoracic

Carcinoma, Ovarian Epithelial, Breast Neoplasms, Carcinoma, Carcinoma, Bronchogenic, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Colonic Neoplasms, Death, Esophageal Neoplasms, Glioblastoma, Lung Diseases, Lung Neoplasms, Melanoma, Myelodysplastic Syndromes, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Glandular and Epithelial, Ovarian Neoplasms, Pancreatic Neoplasms, Rectal Neoplasms, Respiratory Tract Diseases, Respiratory Tract Neoplasms, Sarcoma, Osteosarcoma, Skin Neoplasms, Stomach Neoplasms, Thoracic Neoplasms, Urogenital Neoplasms, Disease Progression, Small Cell Lung Carcinoma

NCT05023928 2025-03-12

Tumor Antigen-sensitized DC Vaccine As an Adjuvant Therapy for Esophagus Cancer

Phase 1 Completed

25 enrolled

Gastrointestinal

Carcinoma, Esophageal Neoplasms

NCT06813079 2025-02-18

Using Tumor Models to Determine Treatments

Phase 2 Not yet recruiting

25 enrolled

Gastrointestinal

Carcinoma, Carcinoma, Pancreatic Ductal

NCT06380816 2024-08-20

A Phase I/II Trial of UCB4594 in Participants With Advanced Cancer

Phase 1/2 Recruiting

167 enrolled

BreastGastrointestinalGynecologicHead & NeckThoracic

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Carcinoma, Non-Small-Cell Lung, Uterine Cervical Neoplasms, Esophageal Neoplasms, Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Triple Negative Breast Neoplasms

NCT06551896 2024-08-13

Pemigatinib and Immune Checkpoint Inhibitor Treated FGFR1/2/3 Alteration Advanced Solid Tumor

Phase 2 Not yet recruiting

30 enrolled

BreastGastrointestinalGenitourinarySarcomaThoracic

Breast Neoplasms, Carcinoma, Carcinoma, Transitional Cell, Lung Neoplasms, Sarcoma, Stomach Neoplasms

NCT06545630 2024-08-09

Tumor Antigen-sensitized DC Vaccine for Colorectal Cancer Liver Metastases

Phase 1 Recruiting

10 enrolled

Gastrointestinal

Carcinoma, Colorectal Neoplasms

NCT03190265 2024-08-07

Study of CRS-207, Nivolumab, and Ipilimumab With or Without GVAX Pancreas Vaccine (With Cy) in Patients With Pancreatic Cancer

Phase 2 Completed

61 enrolled 11 charts

Gastrointestinal

Adenocarcinoma, Carcinoma, Neoplasms, Pancreatic Neoplasms

NCT02539537 2024-01-09

NEOPAN

Phase 3 Completed

171 enrolled

Gastrointestinal

Carcinoma, Pancreatic Neoplasms

NCT06134193 2023-11-18

Combination Therapy of HAIC, Surufatinib and Tislelizumab for Unresectable or Metastatic Biliary Tract Cancer

Phase 2 Unknown

41 enrolled

Gastrointestinal

Carcinoma, Gallbladder Neoplasms, Cholangiocarcinoma

NCT05494060 2023-11-07

EXPLORING

Phase 2 Recruiting

80 enrolled

Gastrointestinal

Carcinoma, Digestive System Diseases, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Stomach Neoplasms

NCT06116019 2023-11-03

ART-02

Recruiting

649 enrolled

GastrointestinalGenitourinaryGynecologicHead & Neck

Urinary Bladder Neoplasms, Carcinoma, Uterine Cervical Neoplasms, Esophageal Neoplasms, Head and Neck Neoplasms, Prostatic Neoplasms, Rectal Neoplasms

NCT04555265 2023-08-31