Clinical Trials

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT05806931 2026-03-18

SCOTI

50 enrolled

Colonic Neoplasms, Rectal Neoplasms

NCT06802991 2026-03-18

Optimised Post-discharge Care in Older Patients After Surgery for Colon Cancer (ERAS 3.0)

Phase NA Recruiting

60 enrolled

Frailty, Colonic Neoplasms

NCT07284849 2026-03-16

A Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer

Phase 3 Recruiting

700 enrolled

Colonic Neoplasms, Colorectal Neoplasms

NCT07474025 2026-03-16

Integrating Peritoneal Histological Growth Patterns Into Preoperative Decision-Making for Colorectal Peritoneal Metastses

Not yet recruiting

30 enrolled

Colonic Neoplasms, Neoplasm Metastasis, Neoplasms, Colorectal Neoplasms

NCT00905047 2026-03-13

COLOCROSS

Phase 3 Completed

89 enrolled

Colonic Neoplasms, Neoplasm Metastasis, Colorectal Neoplasms

NCT03516942 2026-03-13

Financial Burden Assessment in Patients With Stage I-III Colon or Rectal Cancer Undergoing Treatment

Active not recruiting

565 enrolled 16 charts

Phase 1 Active not recruiting

Colonic Neoplasms, Rectal Neoplasms

NCT06607185 2026-03-13

A Study of the Pan-KRAS Inhibitor LY4066434 in Participants With KRAS Mutant Solid Tumors

750 enrolled

GastrointestinalGynecologicThoracic

Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Esophageal Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Ovarian Neoplasms, Pancreatic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms, Cholangiocarcinoma

NCT06654622 2026-03-13

Exosome-based Detection of Molecular Residual Disease in Stage II-III Colorectal Cancer

175 enrolled

Phase 1 Active not recruiting

Colonic Neoplasms, Colorectal Neoplasms

NCT06704724 2026-03-13

A Study to Learn About the Study Medicine PF-07985045 When Given Alone or With Other Anti-cancer Therapies in People With Advanced Solid Tumors That Have a Change in a Gene.

30 enrolled

GastrointestinalThoracic

Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Lung Neoplasms, Rectal Neoplasms, Colorectal Neoplasms, Carcinoma, Pancreatic Ductal

NCT07469709 2026-03-13

PRO-ACTIVE

BreastDermatologicGastrointestinalGynecologicThoracic

850 enrolled

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Melanoma, Ovarian Neoplasms

NCT07470658 2026-03-13

Optimal Surveillance Strategy After Positive FIT and Negative Colonoscopy

Enrolling by invitation

1,274 enrolled

Colonic Neoplasms

NCT04668872 2026-03-12

Biopsy After Radioembolization to Identify Changes in Tumor Cells From the Radiation

80 enrolled

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT06567782 2026-03-12

AZUR-4

120 enrolled

Colonic Neoplasms

NCT07468630 2026-03-12

TRIUNITE-08

106 enrolled

Colonic Neoplasms

NCT00469339 2026-03-11

Risk Communication Within Mexican-American Families

Phase EARLY_PHASE1 Active not recruiting

498 enrolled

BreastGastrointestinal

Breast Neoplasms, Cardiovascular Diseases, Colonic Neoplasms, Diabetes Mellitus

NCT06011772 2026-03-11

EGF-Depleting Therapy CIMAvax-EGF in Combination With Standard Therapy for RAS- and BRAF Wild-Type Metastatic Colorectal Cancer

2 enrolled

Phase NA Enrolling by invitation

Colonic Neoplasms

NCT06191185 2026-03-11

IMPACTT

2,000 enrolled

Phase 3 Active not recruiting

Colonic Neoplasms, Colorectal Neoplasms

NCT01918527 2026-03-10

Neoadjuvant Chemotherapy Versus Standard Treatment in Patients With Locally Advanced Colon Cancer

250 enrolled

Colonic Neoplasms

NCT03446157 2026-03-10

Palbociclib and Cetuximab in Metastatic Colorectal Cancer

Phase 2 Completed

24 enrolled 14 charts

Phase 2/3 Not yet recruiting

Colonic Neoplasms

NCT07462143 2026-03-10

A Phase Ⅱ/Ⅲ Clinical Trial of RC148 Plus Chemotherapy as 1L Therapy for Unresectable or Metastatic Colorectal Cancer

700 enrolled

Colonic Neoplasms

NCT00102011 2026-03-09

00-046

Phase 3 Completed

4,952 enrolled

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT02595957 2026-03-09

Genomic Services Research Program

Phase NA Active not recruiting

5,000 enrolled

BreastGastrointestinal

Breast Neoplasms, Colonic Neoplasms

NCT05677048 2026-03-09

Feasibility Study: IGNITE-TX (Identifying Individuals for Genetic Testing & Treatment) Intervention

205 enrolled

BreastGastrointestinalGynecologic

Breast Neoplasms, Colonic Neoplasms, Colorectal Neoplasms, Hereditary Nonpolyposis, Ovarian Neoplasms, Pancreatic Neoplasms, Uterine Neoplasms, Endometrial Neoplasms, Hereditary Breast and Ovarian Cancer Syndrome

NCT06835569 2026-03-09

A Study to Learn About Study Medicine ALTA3263 in Adults With Advanced Solid Tumors With KRAS Mutations

188 enrolled

GastrointestinalThoracic

Carcinoma, Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Neoplasms, Neoplasms by Site, Pancreatic Neoplasms, Colorectal Neoplasms

NCT06281925 2026-03-06

Cryotherapy & Oxaliplatin

Phase NA Suspended

40 enrolled

Colonic Neoplasms, Peripheral Nervous System Diseases

NCT07432399 2026-03-06

PILDI

100 enrolled

Colonic Neoplasms, Colorectal Neoplasms

NCT00899626 2026-03-05

Gastrointestinal Biomarkers in Tissue and Biological Fluid Samples From Colorectal Cancer Patients

GastrointestinalOther neoplasm

5,000 enrolled

Colonic Neoplasms, Esophageal Neoplasms, Pancreatic Neoplasms, Precancerous Conditions, Stomach Neoplasms, Colorectal Neoplasms, Adenomatous Polyps

NCT03026140 2026-03-05

NICHE

353 enrolled

Phase NA Active not recruiting

Colonic Neoplasms

NCT03151564 2026-03-05

Lesion Detection Assessment in the Liver: Standard vs Low Radiation Dose Using Varied Post-Processing Techniques

146 enrolled

Colonic Neoplasms, Digestive System Diseases, Colorectal Neoplasms

NCT05433142 2026-03-05

Study of XmAb®819 in Subjects With Advanced Clear Cell Renal Cell Carcinoma

GastrointestinalGenitourinaryThoracic

307 enrolled

Carcinoma, Renal Cell, Colonic Neoplasms, Kidney Neoplasms, Lung Neoplasms

NCT05672108 2026-03-05

Phase II Trial of Lung Chemoemobolization

GastrointestinalSarcomaThoracic

30 enrolled

Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Mediastinal Neoplasms, Pleural Neoplasms, Sarcoma

NCT05722327 2026-03-04

Phase I Trial of Adagrasib (MRTX849) in Combination With Cetuximab and Irinotecan in Patients With Colorectal Cancer

Phase 1 Active not recruiting

24 enrolled

Colonic Neoplasms, Colorectal Neoplasms

NCT07448662 2026-03-04

COLBRAIN

Active not recruiting

700 enrolled

CNSGastrointestinal

Brain Neoplasms, Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT07450612 2026-03-04

BEACON

1,200 enrolled

Turcot syndrome, Lynch syndrome I (site-specific colonic cancer), Colonic Diseases, Colonic Neoplasms, Colorectal Neoplasms, Hereditary Nonpolyposis, Colorectal Neoplasms, Lynch Syndrome II

NCT05080673 2026-03-03

FORTE

Phase NA Recruiting

9,500 enrolled

Colonic Neoplasms, Rectal Neoplasms

NCT05174169 2026-03-03

CIRCULATE-US

Phase 2/3 Recruiting

1,912 enrolled

Colonic Neoplasms

NCT07321106 2026-03-03

A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Anti-tumor Activity of CBI-1214 T Cell Engager in Participants With Advanced or Metastatic MSS/MSI-L Colorectal Cancer

80 enrolled

Colonic Neoplasms, Neoplasms, Colorectal Neoplasms

NCT07445178 2026-03-03

Piecemeal Resection and Advanced Histology Independently Predict Local Recurrence After Colorectal Snare-based Endoscopic Resection: a Time-to-event Cohort Study

255 enrolled

Phase 1/2 Active not recruiting

Colonic Neoplasms

NCT04068610 2026-03-02

COLUMBIA-1: Novel Oncology Therapies in Combination With Chemotherapy and Bevacizumab as First- Line Therapy in MSS-CRC

61 enrolled 35 charts

BreastCNSDermatologicGastrointestinalGynecologicHead & NeckLymphoidOther hematologic neoplasmSarcoma

Colonic Neoplasms

NCT05108298 2026-03-02

Improving Adolescent and Young Adult Self-Reported Data in ECOG-ACRIN Trials

Phase NA Recruiting

400 enrolled

Bone Neoplasms, Breast Neoplasms, Uterine Cervical Neoplasms, Colonic Neoplasms, Leukemia, Lymphoma, Melanoma, Sarcoma, Thyroid Neoplasms, Central Nervous System Neoplasms, Pyloric Stenosis, Hypertrophic

NCT07440888 2026-02-27

The Factors Influencing the Success of Redo Surgery and Anal Function for Anastomosis Failure or Local Tumor Recurrence

143 enrolled

Colonic Neoplasms

NCT06447662 2026-02-25

A Study to Learn About the Study Medicine PF-07934040 When Given Alone or With Other Anti-cancer Therapies in People With Advanced Solid Tumors That Have a Genetic Mutation.