Clinical Trials

Esophageal Neoplasms

NCT04780256 2025-10-03

Endoscopic Resection of Gastrointestinal Neoplasms

Recruiting

2,000 enrolled

Colonic Neoplasms, Duodenal Neoplasms, Esophageal Neoplasms, Stomach Neoplasms

NCT07203690 2025-10-02

Development and Application of AI-Based Therapeutic Strategies for Esophageal Cancer Integrating Multimodal Imaging and Digital Pathology

Not yet recruiting

7,000 enrolled

Esophageal Neoplasms

NCT07188103 2025-09-23

Ivonescimab Plus Short-Course Hypofractionated Radiotherapy as Second-Line Therapy for Esophageal Squamous Cell Carcinoma

Phase 2 Recruiting

37 enrolled

Phase NA Active not recruiting

Esophageal Squamous Cell Carcinoma, Esophageal Neoplasms

NCT03161535 2025-07-28

Effectiveness of a Rehabilitation Program in Improving Quality of Life in Patients With Esophageal Cancer

85 enrolled

Phase 2 Not yet recruiting

Esophageal Neoplasms

NCT07046221 2025-07-20

Tislelizumab Combined With Chemotherapy for Resectable Esophageal Squamous Cell Carcinoma Followed by CRT or Surgery

60 enrolled

GastrointestinalGynecologicThoracic

Esophageal Neoplasms

NCT06232083 2025-07-09

A Multi Tumor, Open Phase I Clinical Study on the Progression of First-line Anti-tumor Therapy Using Cardonizumab Combined With Pulsed Low-dose Rate External Irradiation (PLDR)

Phase 1 Recruiting

20 enrolled

Uterine Cervical Neoplasms, Esophageal Neoplasms, Lung Neoplasms

NCT06277921 2025-07-02

ESOSTAT

230 enrolled

Phase 1 Not yet recruiting

Esophageal Neoplasms

NCT07034118 2025-06-24

Definitive Proton Radiotherapy Combined With Chemotherapy and Immunotherapy for Locally Advanced Esophageal Squamous Cell Carcinoma: A Phase I Clinical Study

23 enrolled

Phase NA Not yet recruiting

Esophageal Neoplasms

NCT06979986 2025-05-20

SLND Versus Non-Dissection Following ESD for T1a Stage Esophageal Squamous Cell Carcinoma

102 enrolled

Phase 2 Not yet recruiting

Esophageal Neoplasms

NCT06862479 2025-03-10

ES-LCCE-UDFM

Enrolling by invitation

180 enrolled

GastrointestinalOther

Esophageal Neoplasms, Fistula, Obesity, Obesity, Morbid, Stomach Neoplasms, Anastomotic Leak

NCT06692270 2025-02-28

Tislelizumab as Single-Agent Neoadjuvant Immunotherapy in Resectable Esophageal Squamous Cell Carcinoma

20 enrolled

Esophageal Neoplasms

NCT06833775 2025-02-20

Evaluation of Neoadjuvant Therapy Efficacy and Postoperative Pathological Indicators in Esophageal Cancer Using CT and Multimodal MRI

Not yet recruiting

400 enrolled

Esophageal Neoplasms

NCT06818214 2025-02-10

Mechanistic Study on the Diagnosis of Esophageal Cancer Lymph Node Metastasis Using Spectral CT, Multimodal MRI, FAPI PET-CT, Pathology, and AI Evaluation System

Not yet recruiting

400 enrolled

Esophageal Neoplasms

NCT05937438 2025-01-29

Postoperative Radiotherapy Followed by Immunotherapy for Locally Advanced Esophageal Carcinoma

Phase 1/2 Recruiting

70 enrolled

Phase 1 Not yet recruiting

Esophageal Neoplasms

NCT06760676 2025-01-07

A Multiple Tumor Species, Open and Multi-center Clinical Study of Alpaloritovorelli Antibodies (QL-1706) Combined with Pulsed Low Dose Rate External Irradiation (PLDR) for Disease Progression After Previous Anti-tumor Therapy

90 enrolled

GastrointestinalGynecologicThoracic

Carcinoma, Non-Small-Cell Lung, Uterine Cervical Neoplasms, Esophageal Neoplasms

NCT05628610 2024-08-13

Tislelizumab Combined With Chemotherapy or Radiotherapy in the Treatment of Advanced or Recurrent Metastatic Elderly Esophageal Cancer

Phase 2 Not yet recruiting

130 enrolled

GastrointestinalHead & Neck

Esophageal Neoplasms

NCT06365866 2024-04-15

Evaluate the Efficacy of Adding Intraluminal Brachytherapy After CCRT for Local-regional Thoracic Esophageal Cancer.

Phase NA Recruiting

20 enrolled

Digestive System Diseases, Digestive System Neoplasms, Esophageal Diseases, Esophageal Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Head and Neck Neoplasms, Neoplasms, Neoplasms by Site

NCT06231680 2024-03-29

Thalidomide Prevention or Treatment of Camrelizumab-induced Reactive Cutaneous Capillary Endothelial Proliferation (RCCEP)

132 enrolled

GastrointestinalThoracic

Carcinoma, Non-Small-Cell Lung, Esophageal Neoplasms

NCT06068127 2024-03-15

GESOM

Recruiting

30 enrolled

Esophageal Neoplasms, Gastroparesis

NCT05624099 2023-10-19

Camrelizumab Combined With Chemoradiotherapy in Advanced Esophageal Cancer.

Phase 2 Recruiting

75 enrolled

Digestive System Neoplasms, Esophageal Diseases, Esophageal Neoplasms

NCT04188990 2023-09-21

Cost Effectiveness of an Intervention in Hospitalized Patients With Disease-related Malnutrition

Phase NA Completed

1,051 enrolled

Colitis, Ulcerative, Crohn Disease, Esophageal Neoplasms, Pancreatic Neoplasms, Pancreatitis, Stomach Neoplasms, Colorectal Neoplasms, Inflammatory Bowel Diseases

NCT05688020 2023-08-09

Tranexamic Acid During Upper GI Endoscopic Resection Procedures

Phase 4 Unknown

200 enrolled

Polyposis, Gastric, Duodenal Neoplasms, Esophageal Neoplasms, Stomach Neoplasms

NCT05569668 2022-10-06

Neoadjuvant Chemotherapy Compared With Surgery for Esophageal Carcinoma

826 enrolled

Esophageal Neoplasms

NCT02395705 2022-10-05

Neoadjuvant Chemotherapy Versus Surgery Alone for Esophageal Squamous Cell Carcinoma

528 enrolled

Esophageal Neoplasms

NCT04316078 2022-04-28

A Novel Patient Engagement Platform Among Patients With Gastrointestinal Malignancies

Phase NA Completed

126 enrolled

Colonic Neoplasms, Esophageal Neoplasms, Pancreatic Neoplasms, Rectal Neoplasms, Stomach Neoplasms, Cholangiocarcinoma

NCT05007145 2021-12-21

REVO

92 enrolled

Esophageal Squamous Cell Carcinoma, Esophageal Neoplasms

NCT05013697 2021-08-19

TQB2450 Solution for Injection (TQB2450)+Paclitaxel+Cisplatin ± Anlotinib in the Treatment of Esophageal Cancer.

48 enrolled

Esophageal Neoplasms

NCT03719716 2021-03-09

GI-ACP

Phase NA Completed

46 enrolled

Esophageal Neoplasms, Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms

NCT03032224 2020-07-28

Analysis of Body Composition in Relation to Outcome After Surgery in a Cohort of Patients With Esophageal Cancer

76 enrolled

Deglutition Disorders, Esophageal Neoplasms, Stomach Neoplasms, Sarcopenia

NCT03066167 2020-07-28

Validation of Instruments Used for Assessment of Dysphagia in Patients With Esophageal Cancer

64 enrolled

Deglutition Disorders, Esophageal Neoplasms

NCT03985670 2019-12-12

Teripalimab Plus Chemotherapy in Local Advanced Esophageal Cancer

30 enrolled

GastrointestinalGenitourinaryGynecologicHead & NeckLymphoidSarcoma

Carcinoma, Squamous Cell, Esophageal Neoplasms

NCT04158414 2019-11-08

Applying PET/MR in Oncology - a Prospective Project

Phase NA Unknown

500 enrolled

Uterine Cervical Neoplasms, Esophageal Neoplasms, Lymphoma, Nasopharyngeal Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Sarcoma

NCT01915693 2019-06-04

ROCS

220 enrolled

Esophageal Neoplasms

NCT02741856 2018-10-25

SCOPE2

Phase 2/3 Unknown

584 enrolled

Esophageal Neoplasms

NCT02611245 2018-06-08

NIR Fluorescence Imaging Technique in Thoracic Surgery With ICG

Phase 1 Completed

36 enrolled

GastrointestinalThoracic

Esophageal Neoplasms, Lung Neoplasms

NCT02924909 2018-03-20

QUIMERA

50 enrolled

Esophageal Neoplasms

NCT03415815 2018-01-30

An Observational Study to Evaluate Lymph Metastases and Prognoses of the Patients With Esophageal Cancer

Unknown

3,673 enrolled

Esophageal Neoplasms

NCT01325883 2016-07-12

The Effect of Chemotherapy and Surgery for Cancer on Exercise Capacity

253 enrolled

Esophageal Neoplasms

NCT01998230 2015-10-16

Early Oral Feeding Following Thoracolaparoscopic Oesophagectomy in Patients With Esophageal Cancer

280 enrolled

Esophageal Neoplasms

NCT01843829 2014-03-24

NeoSCOPE

85 enrolled

Esophageal Neoplasms

NCT00665197 2011-10-13

Palliative Radiotherapy and Brachytherapy for Oesophageal Cancer Dysphagia

200 enrolled

Deglutition Disorders, Esophageal Neoplasms

NCT00453323 2010-07-12

Paclitaxel and Capecitabine in Patients With Metastatic/Recurrence Esophageal Cancer

33 enrolled

Esophageal Neoplasms

NCT00559351 2007-11-16

RCT on the Combined Modality Treatment of Squamous Cell Carcinoma of the Esophagus

Phase 3 Terminated

84 enrolled

Esophageal Neoplasms, Neoplasms, Squamous Cell

NCT00193817 2006-02-07

Three Field Radical Esophagectomy Versus Two Field Esophagectomy - a Prospective Trial

Phase 3 Unknown

700 enrolled