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Intestinal Diseases × Gastrointestinal × Clear all

NCT07222800 2026-01-30

A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer

Phase 3 Recruiting

Gastrointestinal

Colonic Diseases, Colonic Neoplasms, Digestive System Diseases, Digestive System Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Intestinal Diseases, Intestinal Neoplasms, Neoplasm Metastasis, Neoplasms by Site, Rectal Diseases, Colorectal Neoplasms

NCT07253298 2025-11-28

BFT in LARS

Phase NA Not yet recruiting

Gastrointestinal

Low Anterior Resection Syndrome, Intestinal Diseases, Rectal Neoplasms

NCT02246725 2025-09-12

ALLAN

Gastrointestinal

Depression, Digestive System Diseases, Digestive System Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Intestinal Diseases, Intestinal Neoplasms, Colorectal Neoplasms

NCT04607421 2025-08-14

A Study of Encorafenib Plus Cetuximab With or Without Chemotherapy in People With Previously Untreated Metastatic Colorectal Cancer

Phase 3 Active not recruiting

831 enrolled 2 FDA

Gastrointestinal

Colonic Diseases, Colonic Neoplasms, Digestive System Diseases, Digestive System Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Intestinal Diseases, Intestinal Neoplasms, Neoplasms, Rectal Diseases, Rectal Neoplasms, Colorectal Neoplasms

NCT07086833 2025-07-25

The Food Environment, Microbial Cysteine Metabolism, and Cancer Disparities

Phase NA Recruiting

Gastrointestinal

Colonic Diseases, Intestinal Diseases, Intestinal Neoplasms, Neoplasms, Colorectal Neoplasms

NCT03093116 2025-07-10

TRIDENT-1

Phase 1/2 Recruiting

500 enrolled 2 FDA

EndocrineGastrointestinalHead & NeckNETSarcomaThoracic

Adenocarcinoma, Bronchial Neoplasms, Carcinoma, Carcinoma, Bronchogenic, Carcinoma, Non-Small-Cell Lung, Colonic Diseases, Colonic Neoplasms, Digestive System Neoplasms, Endocrine System Diseases, Endocrine Gland Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Head and Neck Neoplasms, Intestinal Diseases, Intestinal Neoplasms, Lung Diseases, Lung Neoplasms, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Respiratory Tract Diseases, Respiratory Tract Neoplasms, Sarcoma, Thoracic Neoplasms, Thyroid Diseases, Thyroid Neoplasms, Neuroectodermal Tumors, Carcinoma, Neuroendocrine, Neuroendocrine Tumors

NCT03037385 2025-05-31

ARROW

Phase 1/2 Completed

590 enrolled 58 charts 5 FDA

EndocrineGastrointestinalHead & NeckNETThoracic

Thyroid Cancer, Papillary, Adenocarcinoma, Adenocarcinoma, Papillary, Bronchial Neoplasms, Carcinoma, Carcinoma, Bronchogenic, Carcinoma, Non-Small-Cell Lung, Colonic Diseases, Colonic Neoplasms, Digestive System Diseases, Digestive System Neoplasms, Endocrine System Diseases, Endocrine Gland Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Head and Neck Neoplasms, Intestinal Diseases, Intestinal Neoplasms, Lung Diseases, Lung Neoplasms, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Glandular and Epithelial, Neoplasms, Nerve Tissue, Respiratory Tract Diseases, Respiratory Tract Neoplasms, Thoracic Neoplasms, Thyroid Diseases, Thyroid Neoplasms, Colorectal Neoplasms, Neuroectodermal Tumors, Carcinoma, Medullary, Carcinoma, Neuroendocrine, Neuroendocrine Tumors, Multiple Endocrine Neoplasia Type 2a

NCT05551052 2025-05-29

CRC-DRAW

Active not recruiting

Gastrointestinal

Adenoma, Colonic Diseases, Colonic Diseases, Functional, Colonic Neoplasms, Colonic Polyps, Gastrointestinal Neoplasms, Intestinal Diseases, Intestinal Neoplasms, Polyps, Rectal Diseases, Rectal Neoplasms, Colorectal Neoplasms

NCT01550510 2025-05-06

Research Study of IV Vitamin C in Combination With Irinotecan vs Irinotecan Alone for Advanced Colorectal CA

Phase 1/2 Terminated

4 enrolled 5 charts

Gastrointestinal

Colonic Diseases, Digestive System Diseases, Digestive System Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Intestinal Diseases, Intestinal Neoplasms, Neoplasms, Neoplasms by Site, Rectal Diseases, Colorectal Neoplasms

NCT06524362 2024-07-29

PERECARE

Phase NA Not yet recruiting

Gastrointestinal

Low Anterior Resection Syndrome, Fecal Incontinence, Intestinal Diseases, Rectal Neoplasms

NCT06435975 2024-05-30

Physical Activity in Rectal Cancer Survivors

Phase NA Completed

Gastrointestinal

Intestinal Diseases, Motor Activity, Rectal Neoplasms

NCT02831556 2024-05-21

Point of Care 3D Ultrasound for Various Applications: A Pilot Study

GastrointestinalGenitourinaryGynecologic

Abdominal Injuries, Aortic Aneurysm, Appendicitis, Digestive System Diseases, Diverticulitis, Gastrointestinal Diseases, Intestinal Diseases, Kidney Calculi, Leiomyoma, Neoplasms, Ovarian Cysts, Pancreatitis, Polyps, Pregnancy, Ectopic, Vascular Diseases, Gallstones, Intraabdominal Infections

NCT04755920 2024-05-09

SGM-CBM

Phase 2 Recruiting

CNSGastrointestinal

Brain Diseases, Brain Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Intestinal Diseases, Intestinal Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00838578 2024-04-26

Phase I/II Study of KRN330 Plus Irinotecan in Patients With Metastatic Colorectal Cancer

Phase 1/2 Terminated

65 enrolled 7 charts

Gastrointestinal

Colonic Diseases, Digestive System Diseases, Digestive System Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Intestinal Diseases, Intestinal Neoplasms, Neoplasms, Neoplasms by Site, Rectal Diseases, Colorectal Neoplasms

NCT03464305 2024-03-19

ASPIRIN

Phase 3 Active not recruiting

Gastrointestinal

Colonic Diseases, Colonic Neoplasms, Digestive System Diseases, Digestive System Neoplasms, Gastrointestinal Neoplasms, Intestinal Diseases, Intestinal Neoplasms, Neoplasms, Neoplasms by Site, Pathologic Processes, Recurrence, Colorectal Neoplasms, Disease Attributes

NCT03559543 2024-02-07

Evaluation of Ocoxin®-Viusid® in Metastatic Colorectal Adenocarcinoma

Phase 2 Completed

Gastrointestinal

Colonic Diseases, Digestive System Diseases, Digestive System Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Intestinal Diseases, Intestinal Neoplasms, Rectal Diseases, Colorectal Neoplasms

NCT02753127 2023-11-15

CanStem303C

Phase 3 Completed

1,253 enrolled 18 charts

Gastrointestinal

Colonic Diseases, Digestive System Diseases, Digestive System Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Intestinal Diseases, Intestinal Neoplasms, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Glandular and Epithelial, Rectal Diseases, Colorectal Neoplasms

NCT04644315 2023-08-07

ALpha-T

Phase 2 Terminated

1 enrolled 5 charts

BreastCNSDermatologicEndocrineGastrointestinalGenitourinaryGynecologicHead & NeckLymphoidNETSarcomaThoracic

Thyroid Cancer, Papillary, Brain Neoplasms, Breast Neoplasms, Bronchial Neoplasms, Carcinoma, Bronchogenic, Carcinoma, Renal Cell, Colonic Diseases, Digestive System Diseases, Digestive System Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Head and Neck Neoplasms, Intestinal Diseases, Intestinal Neoplasms, Melanoma, Neoplasms, Neoplasms by Site, Ovarian Neoplasms, Pancreatic Neoplasms, Respiratory Tract Diseases, Respiratory Tract Neoplasms, Salivary Gland Neoplasms, Sarcoma, Thoracic Neoplasms, Thyroid Neoplasms, Colorectal Neoplasms, Lymphoma, Large-Cell, Anaplastic, Cholangiocarcinoma, Neuroendocrine Tumors

NCT05605600 2023-04-05

Translation of the International Consensus Definition of LARS Into a Bowl Dysfunction Severity Scoring Tool (New LARS Score)

Gastrointestinal

Low Anterior Resection Syndrome, Intestinal Diseases, Colorectal Neoplasms

NCT04970316 2023-02-28

LOSAPEX

GastrointestinalOther

Intestinal Diseases, Lymphedema, Pain, Sexual Dysfunction, Physiological, Colorectal Neoplasms

NCT04949282 2022-12-23

SEPTRALU

EndocrineGastrointestinalNET

Gastro-enteropancreatic neuroendocrine tumor, Digestive System Diseases, Digestive System Neoplasms, Endocrine System Diseases, Endocrine Gland Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Intestinal Diseases, Intestinal Neoplasms, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, Pancreatic Diseases, Pancreatic Neoplasms, Stomach Neoplasms, Neuroectodermal Tumors, Neuroendocrine Tumors

NCT04893876 2022-08-18

The OPERa Study: Evaluating QoL After Rectal Cancer Surgery

Not yet recruiting

GastrointestinalOther

Intestinal Diseases, Rectal Neoplasms, Sexual Dysfunction, Physiological

NCT04080843 2022-07-13

ALTER-C-002

Phase 2 Completed

Gastrointestinal

Colonic Diseases, Digestive System Diseases, Digestive System Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Intestinal Diseases, Intestinal Neoplasms, Neoplasms, Neoplasms by Site, Rectal Diseases, Colorectal Neoplasms

NCT05322486 2022-04-11

Palliative Primary Tumor Resection in Minimally Symptomatic Patients With Colorectal Cancer and Synchronous Unresectable Metastases

Gastrointestinal

Colonic Diseases, Digestive System Diseases, Digestive System Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Intestinal Diseases, Intestinal Neoplasms, Neoplasm Metastasis, Neoplasms, Neoplasms by Site, Rectal Diseases, Colorectal Neoplasms, Neoplasms, Second Primary

NCT01966289 2021-03-30

SGI-110 in Combination With an Allogeneic Colon Cancer Cell Vaccine (GVAX) and Cyclophosphamide (CY) in Metastatic Colorectal Cancer (mCRC)

Phase 1 Completed

Gastrointestinal

Colonic Diseases, Digestive System Diseases, Digestive System Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Intestinal Diseases, Intestinal Neoplasms, Neoplasms, Neoplasms by Site, Rectal Diseases, Colorectal Neoplasms

NCT03723447 2021-02-17

TINGLE

Phase 4 Completed

102 enrolled 9 charts

Gastrointestinal

Crohn Disease, Digestive System Diseases, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Intestinal Diseases, Neuralgia, Pain, Pain, Postoperative, Colorectal Neoplasms, Inflammatory Bowel Diseases

NCT02981524 2021-02-10

Study of GVAX (With CY) and Pembrolizumab in MMR-p Advanced Colorectal Cancer

Phase 2 Completed

17 enrolled 12 charts

Gastrointestinal

Colonic Diseases, Digestive System Diseases, Digestive System Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Intestinal Diseases, Neoplasms, Neoplasms by Site, Rectal Diseases, Colorectal Neoplasms

NCT04733794 2021-02-03

Feasibility Bowel Dysfunction Program After Low Anterior Resection

Phase NA Completed

Gastrointestinal

Intestinal Diseases, Rectal Neoplasms

NCT04662853 2020-12-10

CCR-microbiota

Gastrointestinal

Colonic Neoplasms, Disease, Intestinal Diseases, Neoplasms

NCT04287335 2020-12-08

CLEAR-C

Gastrointestinal

Adenoma, Colonic Diseases, Digestive System Diseases, Digestive System Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Intestinal Diseases, Intestinal Neoplasms, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Rectal Diseases, Colorectal Neoplasms, Adenomatous Polyps

NCT01397305 2020-09-09

An Extended Feasibility Phase I/II Study of Methylenetetrahydrofolate (Arfolitixorin) and Pemetrexed Single Agent, Given as Neoadjuvant Treatment in Patients With Resectable Rectal Cancer

Phase 1/2 Completed

Gastrointestinal

Digestive System Diseases, Digestive System Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Intestinal Diseases, Intestinal Neoplasms, Neoplasms, Neoplasms by Site, Rectal Diseases, Rectal Neoplasms, Colorectal Neoplasms

NCT03920202 2019-04-18

LongLARS

Gastrointestinal

Low Anterior Resection Syndrome, Intestinal Diseases, Rectal Neoplasms, Irritable Bowel Syndrome

NCT02785783 2019-02-04

Erings™

Phase NA Completed

Gastrointestinal

Digestive System Diseases, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Intestinal Diseases, Intestinal Neoplasms

NCT02005965 2018-09-18

MERCURY II

Gastrointestinal

Adenocarcinoma, Carcinoma, Adenocarcinoma, Mucinous, Digestive System Diseases, Digestive System Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Intestinal Diseases, Intestinal Neoplasms, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Glandular and Epithelial, Rectal Diseases, Rectal Neoplasms, Colorectal Neoplasms, Neoplasms, Cystic, Mucinous, and Serous

NCT01037049 2018-09-17

Optimum Timing for Surgery After Pre-operative Radiotherapy 6 vs 12 Weeks

Phase 2 Unknown

Gastrointestinal

Adenocarcinoma, Carcinoma, Adenocarcinoma, Mucinous, Digestive System Diseases, Digestive System Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Intestinal Diseases, Intestinal Neoplasms, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Glandular and Epithelial, Rectal Diseases, Rectal Neoplasms, Colorectal Neoplasms, Neoplasms, Cystic, Mucinous, and Serous

NCT01995942 2018-09-14

MARVEL

Gastrointestinal

Adenocarcinoma, Carcinoma, Adenocarcinoma, Mucinous, Digestive System Diseases, Digestive System Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Intestinal Diseases, Intestinal Neoplasms, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Glandular and Epithelial, Rectal Diseases, Rectal Neoplasms, Colorectal Neoplasms, Neoplasms, Cystic, Mucinous, and Serous

NCT03072472 2018-09-06

B-ADENOMA

Phase NA Completed

GastrointestinalOther neoplasm

Adenoma, Colonic Diseases, Colonic Polyps, Digestive System Diseases, Digestive System Neoplasms, Intestinal Diseases, Intestinal Neoplasms, Intestinal Polyps, Neoplasms, Glandular and Epithelial, Polyps, Rectal Diseases, Colorectal Neoplasms, Pathological Conditions, Anatomical

NCT02503631 2018-04-06

Stool Sample Collection Protocol for Development of Screening Test for Colorectal Cancer and Other Digestive Tract Cancers

Gastrointestinal

Colonic Diseases, Digestive System Diseases, Digestive System Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Intestinal Diseases, Intestinal Neoplasms, Neoplasms, Neoplasms by Site, Rectal Diseases, Colorectal Neoplasms

NCT01177007 2017-08-28

Intra-arterial Y-90 TheraSpheres for Hepatic Metastases From Solid Tumors

Phase 2 Completed

50 enrolled 10 charts

EndocrineGastrointestinalNET

Adenocarcinoma, Carcinoma, Colonic Diseases, Digestive System Diseases, Digestive System Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Intestinal Diseases, Intestinal Neoplasms, Liver Diseases, Liver Neoplasms, Neoplasm Metastasis, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Glandular and Epithelial, Neoplasms, Nerve Tissue, Neoplastic Processes, Pathologic Processes, Rectal Diseases, Colorectal Neoplasms, Neuroectodermal Tumors, Carcinoma, Neuroendocrine, Neuroendocrine Tumors

NCT02141945 2017-03-28

Microbiome Test for the Detection of Colorectal Polyps and Cancer

Gastrointestinal

Colonic Diseases, Colonic Neoplasms, Digestive System Diseases, Digestive System Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Intestinal Diseases, Intestinal Neoplasms, Neoplasms, Neoplasms by Site, Rectal Diseases, Colorectal Neoplasms

NCT01819766 2017-02-17

OCEANIA

Gastrointestinal

Colonic Diseases, Digestive System Diseases, Digestive System Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Intestinal Diseases, Intestinal Neoplasms, Neoplasms, Neoplasms by Site, Colorectal Neoplasms, Cholangitis, Sclerosing, Inflammatory Bowel Diseases

NCT03009747 2017-01-04

PMCRBDSPS

Gastrointestinal

Intestinal Diseases, Rectal Neoplasms

NCT02503696 2016-08-10

Sample Collection Study to Evaluate DNA Markers in Subjects With Inflammatory Bowel Disease (IBD)

Gastrointestinal

Colonic Diseases, Digestive System Diseases, Digestive System Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Intestinal Diseases, Intestinal Neoplasms, Neoplasms, Neoplasms by Site, Rectal Diseases, Colorectal Neoplasms, Inflammatory Bowel Diseases

NCT01397747 2015-12-03

DeeP-C

12,776 enrolled 8 charts

Gastrointestinal

Colonic Diseases, Digestive System Diseases, Digestive System Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Intestinal Diseases, Intestinal Neoplasms, Neoplasms, Neoplasms by Site, Rectal Diseases, Colorectal Neoplasms

NCT01269567 2015-07-23

GRECCAR 5

Phase 3 Completed

Gastrointestinal

Digestive System Diseases, Digestive System Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Intestinal Diseases, Intestinal Neoplasms, Neoplasms by Site, Rectal Diseases, Colorectal Neoplasms

NCT01260168 2015-05-13

Multi-marker Stool Test for Detection of Colorectal Neoplasia: Marker Panel Selection and Technical Development Studies

Gastrointestinal

Colonic Diseases, Digestive System Diseases, Digestive System Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Intestinal Diseases, Intestinal Neoplasms, Neoplasms, Neoplasms by Site, Rectal Diseases, Colorectal Neoplasms

NCT01600209 2015-05-13

Exact CRC Screening Test: Stool Sample Collection Study to Support Assay Validation Testing

Gastrointestinal

Colonic Diseases, Digestive System Diseases, Digestive System Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Intestinal Diseases, Intestinal Neoplasms, Neoplasms, Neoplasms by Site, Rectal Diseases, Colorectal Neoplasms

NCT00808743 2013-05-16

PreDuoFAP

Phase 2/3 Completed

Gastrointestinal

Adenoma, Digestive System Diseases, Digestive System Neoplasms, Duodenal Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Intestinal Diseases, Intestinal Neoplasms, Neoplastic Syndromes, Hereditary, Adenomatous Polyposis Coli, Polyps, Adenomatous Polyps, Genetic Diseases, Inborn

NCT01549418 2012-03-09

ASAPOL

Phase 4 Unknown

Gastrointestinal

Colonic Diseases, Digestive System Diseases, Digestive System Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Gastrointestinal Hemorrhage, Intestinal Diseases, Intestinal Neoplasms, Neoplasms, Neoplasms by Site, Rectal Diseases, Colorectal Neoplasms