Clinical Trials

100 enrolled

Adenocarcinoma, Carcinoma, Digestive System Diseases, Digestive System Neoplasms, Carcinoma, Hepatocellular, Liver Diseases, Liver Neoplasms, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Glandular and Epithelial

NCT03993353 2026-02-12

Tadalafil and Pembrolizumab in Recurrent or Metastatic Head and Neck Cancer

GastrointestinalHead & Neck

7 enrolled 14 charts

Pyridoxine-dependent epilepsy, Parkinson Disease 4, Autosomal Dominant Lewy Body, Squamous Cell Carcinoma of Head and Neck, Carcinoma, Esophageal Neoplasms, Head and Neck Neoplasms, Mouth Neoplasms, Neoplasm Metastasis, Neoplasms

NCT07405736 2026-02-12

Lubiprostone Combined With Maintenance Therapy for Prevention of Postoperative Recurrence in Peritoneal Metastatic Colorectal Cancer

124 enrolled

Neoplasm Metastasis, Neoplasms, Colorectal Neoplasms

NCT07354919 2026-01-21

AxeCan

BreastGastrointestinalGenitourinaryThoracic

34 enrolled

Breast Neoplasms, Lung Neoplasms, Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms

NCT05152472 2026-01-08

ATEZOGIST

110 enrolled

GastrointestinalSarcoma

Neoplasms, Gastrointestinal Stromal Tumors

NCT04141449 2025-12-31

Potlako+

BreastGastrointestinalGynecologicHead & Neck

874 enrolled

Squamous Cell Carcinoma of Head and Neck, Acquired Immunodeficiency Syndrome, Anus Neoplasms, Breast Neoplasms, Uterine Cervical Neoplasms, Neoplasms, Vulvar Neoplasms

NCT05257590 2025-12-17

CVM-1118 in Combination With Nivolumab for Unresectable Advanced Hepatocellular Carcinoma

95 enrolled

Carcinoma, Hepatocellular, Neoplasms

NCT06846346 2025-11-28

GRACIE

88 enrolled

Adenocarcinoma Of Esophagus, Adenocarcinoma, Neoplasm Metastasis, Neoplasms

NCT02576431 2025-11-12

NAVIGATE

BreastDermatologicGastrointestinalHead & NeckSarcomaThoracic

215 enrolled 3 FDA

Biliary Tract Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Melanoma, Neoplasms, Salivary Gland Neoplasms, Sarcoma, Thyroid Neoplasms, Colorectal Neoplasms

NCT03505320 2025-10-20

ILUSTRO

143 enrolled

Neoplasms, Stomach Neoplasms

NCT04363801 2025-10-09

DisTinGuish

247 enrolled 38 charts

Adenocarcinoma, Neoplasms, Stomach Neoplasms

NCT03915678 2025-10-06

AGADIR

BreastDermatologicGastrointestinalGenitourinaryThoracic

247 enrolled

Urinary Bladder Neoplasms, Carcinoma, Non-Small-Cell Lung, Melanoma, Neoplasm Metastasis, Neoplasms, Pancreatic Neoplasms, Triple Negative Breast Neoplasms

NCT05221320 2025-09-25

Trial of Ulixertinib in Combination With Hydroxychloroquine in Patients With Advanced Gastrointestinal (GI) Malignancies

47 enrolled 18 charts

Gastrointestinal Neoplasms, Neoplasms

NCT03929666 2025-09-12

A Safety and Efficacy Study of ZW25 (Zanidatamab) Plus Combination Chemotherapy in HER2-expressing Gastrointestinal Cancers, Including Gastroesophageal Adenocarcinoma, Biliary Tract Cancer, and Colorectal Cancer

74 enrolled

Biliary Tract Neoplasms, Esophageal Neoplasms, Gastrointestinal Neoplasms, Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Cholangiocarcinoma

NCT05678257 2025-09-12

A Study of NUC-3373 in Combination With Other Agents in Patients With Colorectal Cancer

180 enrolled 16 charts

Colonic Neoplasms, Neoplasm Metastasis, Neoplasms, Colorectal Neoplasms

NCT06690281 2025-09-11

A Phase II Study of Adjuvant Immunotherapy Targeting KRAS G12D, KRAS G12V, or TP53 R175H for Participants With Advanced Gastrointestinal Malignancies

Phase 2 Withdrawn

Duodenal Neoplasms, Liver Neoplasms, Neoplasms, Pancreatic Neoplasms, Colorectal Neoplasms, Cholangiocarcinoma

NCT00924027 2025-09-05

A Study of Patients Receiving High-Dose Rate Brachytherapy

GastrointestinalGenitourinaryGynecologic

43 enrolled 13 charts

Biliary Tract Neoplasms, Uterine Cervical Neoplasms, Esophageal Neoplasms, Neoplasms, Prostatic Neoplasms, Endometrial Neoplasms

NCT05822752 2025-08-14

LIVIGNO-1

130 enrolled

Carcinoma, Hepatocellular, Neoplasms

NCT03697564 2025-08-06

Nivolumab + Cabiralizumab + Gemcitabine in Patients With Stage IV Pancreatic Cancer

2 enrolled 10 charts

Neoplasms, Pancreatic Neoplasms

NCT02078700 2025-06-25

Feasibility of an Early Palliative Care Intervention for Metastatic Cancer Patients. A Phase 2 Study.

GastrointestinalOther solid neoplasmThoracic

40 enrolled

Lung Neoplasms, Mesothelioma, Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms

NCT07018063 2025-06-12

YOUNG-NEOS

35 enrolled

Neoplasms, Stomach Neoplasms

NCT03611712 2025-06-04

PG2 Concurrent With Chemoradiation for Locally Advanced Esophageal Cancer

48 enrolled

Esophageal Neoplasms, Neoplasms

NCT05546476 2025-05-31

PROACC-1

187 enrolled 24 charts

GastrointestinalThoracic

Anorexia, Cachexia, Carcinoma, Non-Small-Cell Lung, Fatigue, Neoplasms, Pancreatic Neoplasms, Colorectal Neoplasms, Weight Loss

NCT06978400 2025-05-18

A Study of Dabrafenib Plus Cetuximab/Panitumumab With FOLFOX in the First Line of Therapy in People With Metastatic Colorectal Cancer

64 enrolled

Neoplasms, Colorectal Neoplasms

NCT06589830 2025-05-15

TL938 and Trastuzumab for Patients With HER2-positive Metastatic Colorectal Cancer

80 enrolled

Neoplasms, Colorectal Neoplasms

NCT01555489 2025-05-04

Assessing the Efficacy and Safety of IV Vitamin C in Combination With Standard Chemotherapy for Pancreatic Ca

11 enrolled 8 charts

Digestive System Diseases, Digestive System Neoplasms, Endocrine System Diseases, Endocrine Gland Neoplasms, Neoplasms, Neoplasms by Site, Pancreatic Diseases, Pancreatic Neoplasms

NCT02699606 2025-04-27

A Study to Evaluate the Clinical Efficacy of JNJ-42756493 (Erdafitinib), A Pan-Fibroblast Growth Factor Receptor (FGFR) Tyrosine Kinase Inhibitor, In Asian Participants With Advanced Non-Small-Cell Lung Cancer, Urothelial Cancer, Esophageal Cancer Or Cholangiocarcinoma

35 enrolled

GastrointestinalThoracic

Acrocephalosyndactylia, Carcinoma, Non-Small-Cell Lung, Esophageal Neoplasms, Neoplasms, Cholangiocarcinoma

NCT02650804 2025-03-26

BPM31510 Administered Intravenously With Gemcitabine in Advanced Pancreatic Cancer Patients

45 enrolled 14 charts

Neoplasms, Pancreatic Neoplasms

NCT05304481 2025-03-06

Efficacy and Safety of Activated T Lymphocytes (ATL) in Hepatocellular Carcinoma

95 enrolled

Carcinoma, Hepatocellular, Neoplasms

NCT06475352 2025-01-27

FUDOSE

400 enrolled

Gastrointestinal Neoplasms, Neoplasm Metastasis, Neoplasms, Recurrence, Colorectal Neoplasms

NCT06119217 2024-12-04

Phase 2 Study of TTX-030 and Chemotherapy With or Without Budigalimab for 1L mPDAC Patients

194 enrolled

Neoplasm Metastasis, Neoplasms, Pancreatic Neoplasms

NCT03678883 2024-11-07

9-ING-41 in Patients with Advanced Cancers

BreastCNSGastrointestinalGenitourinaryLymphoidOther hematologic neoplasmSarcomaThoracic

350 enrolled

Bone Neoplasms, Breast Neoplasms, Glioma, Kidney Neoplasms, Lung Neoplasms, Lymphoma, Non-Hodgkin, Neoplasm Metastasis, Neoplasms, Hereditary Sensory and Autonomic Neuropathies, Pancreatic Neoplasms, Sarcoma, Colorectal Neoplasms, Leukemia-Lymphoma, Adult T-Cell

NCT03556384 2024-11-04

Temozolomide (TMZ) in Advanced Succinate Dehydrogenase (SDH)-Mutant/Deficient Gastrointestinal Stromal Tumor (GIST)

23 enrolled

GastrointestinalSarcoma

Hematoma, Subdural, Neoplasms, Gastrointestinal Stromal Tumors

NCT06575127 2024-08-28

Modified FOLFOXIRI Plus Target Therapy as a First Line Treatment for Advanced Colorectal Cancer a Prospective Phase Two Study

60 enrolled

Colonic Neoplasms, Neoplasms

NCT00378482 2024-08-22

A Rollover Study for Patients Who Received Tremelimumab in Other Protocols, to Allow the Patients Access to Tremelimumab Until This Agent Becomes Commercially Available or Development is Discontinued.

DermatologicGastrointestinalGenitourinary

37 enrolled 13 charts

Carcinoma, Renal Cell, Melanoma, Neoplasms, Prostatic Neoplasms, Colorectal Neoplasms

NCT01863745 2024-08-19

Nilotinib Roll-over Protocol for Patients in Novartis-sponsored Nilotinib Study and Benefiting From Nilotinib Treatment

15 enrolled 7 charts

GastrointestinalSarcoma

Neoplasms, Gastrointestinal Stromal Tumors

NCT03274882 2024-07-25

Study of Efficacy and Safety of S 95005 (TAS-102) in Patients With Metastatic Colorectal Cancer Who Failed Standard Chemotherapies

26 enrolled

Neoplasm Metastasis, Neoplasms, Colorectal Neoplasms

NCT02091141 2024-07-23

My Pathway: A Study Evaluating Herceptin/Perjeta, Tarceva, Zelboraf/Cotellic, Erivedge, Alecensa, and Tecentriq Treatment Targeted Against Certain Molecular Alterations in Participants With Advanced Solid Tumors

GastrointestinalGenitourinary

673 enrolled 22 charts

Biliary Tract Neoplasms, Urinary Bladder Neoplasms, Neoplasms

NCT02352337 2024-07-10

PANOPTIMOX

276 enrolled 12 charts

Neoplasms, Pancreatic Neoplasms

NCT02842580 2024-07-10

HIGH-LIGHT

21 enrolled 12 charts

Neoplasm Metastasis, Neoplasms, Colorectal Neoplasms

NCT00940225 2024-04-25

Study of Cabozantinib (XL184) in Adults With Advanced Malignancies

BreastDermatologicGastrointestinalGenitourinaryGynecologicThoracic

730 enrolled 25 charts

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Hepatocellular, Melanoma, Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Small Cell Lung Carcinoma

NCT03339843 2024-03-15

MiMe-A

GastrointestinalGenitourinaryGynecologic

85 enrolled

Adenocarcinoma Of Esophagus, Esophageal Squamous Cell Carcinoma, Neoplasms, Urologic Neoplasms, Endometrial Neoplasms, Cholangiocarcinoma

NCT06229340 2024-01-29

NТО-RAS